Gene Symbol | Wasf2 |
Entrez Gene ID | 242687 |
Full Name | WAS protein family, member 2 |
Synonyms | AW742646,D4Ertd13e,WAVE2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Wasf2 cDNA ORF clone
gRNAs
Gene Symbol | Wasf2 |
Entrez Gene ID | 242687 |
Full Name | WAS protein family, member 2 |
Synonyms | AW742646,D4Ertd13e,WAVE2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006538849.3 | XP_006538912.1 | wiskott-Aldrich syndrome protein family member 2 isoform X1 |
XM_006538848.4 | XP_006538911.1 | wiskott-Aldrich syndrome protein family member 2 isoform X1 |
NM_153423.6 | NP_700472.1 | wiskott-Aldrich syndrome protein family member 2 |
XM_006538850.4 | XP_006538913.1 | wiskott-Aldrich syndrome protein family member 2 isoform X1 |
XM_006538850.3 | XP_006538913.1 | wiskott-Aldrich syndrome protein family member 2 isoform X1 |
XM_006538848.3 | XP_006538911.1 | wiskott-Aldrich syndrome protein family member 2 isoform X1 |
XM_006538849.4 | XP_006538912.1 | wiskott-Aldrich syndrome protein family member 2 isoform X1 |
Bos taurus (cattle) | WASF2 | NP_001074980.1 |
Mus musculus (house mouse) | Wasf2 | NP_700472.1 |
Gallus gallus (chicken) | WASF2 | XP_424015.3 |
Danio rerio (zebrafish) | wasf2 | NP_957375.1 |
Pan troglodytes (chimpanzee) | WASF2 | XP_513245.3 |
Homo sapiens (human) | WASF2 | NP_008921.1 |
LOC716082 | XP_001111312.2 | |
Canis lupus familiaris (dog) | WASF2 | XP_544469.1 |
Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
Gromnitza S, Lepa C, Weide T, Schwab A, Pavenst?dt H, George B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology(2017 Nov)
Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)
The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.
Sudhaharan T, Sem KP, Liew HF, Yu YH, Goh WI, Chou AM, Ahmed S
Journal of cell science129(14)2829-40(2016 07)
Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics.
Roybal KT, Buck TE, Ruan X, Cho BH, Clark DJ, Ambler R, Tunbridge HM, Zhang J, Verkade P, W?lfing C, Murphy RF
Science signaling9(424)rs3(2016 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology.
Title: The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.
Data show that the primary effect of costimulation blockade was to decrease recruitment of the activator of actin nucleation WAVE2 (Wiskott-Aldrich syndrome protein family member protein 2) and cofilin (actin-severing protein) to F-actin.
Title: Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics.
The expression of NESH/Abi-3 caused degradation of endogenous Abi-1, which led to the formation of a NESH/Abi-3-based WAVE2 complex.
Title: The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.
Results of the present study show that the nucleation-promoting factors JMY and WAVE2 are critical for cytokinesis during development of mouse embryos.
Title: Role of nucleation-promoting factors in mouse early embryo development.
These results identify Wasf2 as a novel target of intermittent PTH administration via the Wnt and phosphoinositide-dependent protein kinase signaling pathways.
Title: Wasf2: a novel target of intermittent parathyroid hormone administration.
The following Wasf2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wasf2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu15996 | |
Clone ID Related Accession (Same CDS sequence) | XM_006538849.3 , XM_006538848.4 , NM_153423.6 , XM_006538850.4 , XM_006538850.3 , XM_006538848.3 , XM_006538849.4 | |
Accession Version | NM_153423.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-20 | |
Organism | Mus musculus(house mouse) | |
Product | wiskott-Aldrich syndrome protein family member 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL671858.6. On Oct 19, 2007 this sequence version replaced NM_153423.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK085458.1, AK150140.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_700472.1 |
CDS | 139..1632 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15996 | |
Clone ID Related Accession (Same CDS sequence) | XM_006538849.3 , XM_006538848.4 , NM_153423.6 , XM_006538850.4 , XM_006538850.3 , XM_006538848.3 , XM_006538849.4 | |
Accession Version | XM_006538849.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | wiskott-Aldrich syndrome protein family member 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538849.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006538912.1 |
CDS | 386..1879 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15996 | |
Clone ID Related Accession (Same CDS sequence) | XM_006538849.3 , XM_006538848.4 , NM_153423.6 , XM_006538850.4 , XM_006538850.3 , XM_006538848.3 , XM_006538849.4 | |
Accession Version | XM_006538850.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | wiskott-Aldrich syndrome protein family member 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538850.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006538913.1 |
CDS | 236..1729 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15996 | |
Clone ID Related Accession (Same CDS sequence) | XM_006538849.3 , XM_006538848.4 , NM_153423.6 , XM_006538850.4 , XM_006538850.3 , XM_006538848.3 , XM_006538849.4 | |
Accession Version | XM_006538848.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | wiskott-Aldrich syndrome protein family member 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538848.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006538911.1 |
CDS | 108..1601 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15996 | |
Clone ID Related Accession (Same CDS sequence) | XM_006538849.3 , XM_006538848.4 , NM_153423.6 , XM_006538850.4 , XM_006538850.3 , XM_006538848.3 , XM_006538849.4 | |
Accession Version | XM_006538848.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | wiskott-Aldrich syndrome protein family member 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006538848.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006538911.1 |
CDS | 108..1601 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15996 | |
Clone ID Related Accession (Same CDS sequence) | XM_006538849.3 , XM_006538848.4 , NM_153423.6 , XM_006538850.4 , XM_006538850.3 , XM_006538848.3 , XM_006538849.4 | |
Accession Version | XM_006538850.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | wiskott-Aldrich syndrome protein family member 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006538850.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006538913.1 |
CDS | 236..1729 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15996 | |
Clone ID Related Accession (Same CDS sequence) | XM_006538849.3 , XM_006538848.4 , NM_153423.6 , XM_006538850.4 , XM_006538850.3 , XM_006538848.3 , XM_006538849.4 | |
Accession Version | XM_006538849.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | wiskott-Aldrich syndrome protein family member 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006538849.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006538912.1 |
CDS | 386..1879 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTAG TAACCAGGAA CATCGAGCCA AGGCACCTGT GCCGTCAGAC GTTGCCTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation. |
Evolution of complexity in the zebrafish synapse proteome. |
The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia. |
Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics. |