About the NGF signalling via TRKA from the plasma membrane pathway
Trk receptors signal from the plasma membrane and from intracellular membranes, particularly from early endosomes. Signalling from the plasma membrane is fast but transient; signalling from endosomes is slower but long lasting. Signalling from the plasma membrane is annotated here.
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
356 gene Click for more »
| Gene Symbol | Full Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADCY3 | adenylate cyclase 3 |
| ADCY5 | adenylate cyclase 5 |
| ADCY6 | adenylate cyclase 6 |
| ADCY7 | adenylate cyclase 7 |
| ADCY8 | adenylate cyclase 8 (brain) |
| ADCY9 | adenylate cyclase 9 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) |
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I |
| ADORA2A | adenosine A2a receptor |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ANGPT1 | angiopoietin 1 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| RHOA | ras homolog family member A |
| ARRB1 | arrestin, beta 1 |
| ARRB2 | arrestin, beta 2 |
| ATF1 | activating transcription factor 1 |
| BAD | BCL2-associated agonist of cell death |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTC | betacellulin |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CD19 | CD19 molecule |
| CD28 | CD28 molecule |
| CD80 | CD80 molecule |
| CD86 | CD86 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit |
| CLTA | clathrin, light chain A |
| CREB1 | cAMP responsive element binding protein 1 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| MAPK14 | mitogen-activated protein kinase 14 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CSK | c-src tyrosine kinase |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DNM1 | dynamin 1 |
| DNM2 | dynamin 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP3 | dual specificity phosphatase 3 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP6 | dual specificity phosphatase 6 |
| DUSP7 | dual specificity phosphatase 7 |
| DUSP8 | dual specificity phosphatase 8 |
| DUSP9 | dual specificity phosphatase 9 |
| EGF | epidermal growth factor |
| EGFR | epidermal growth factor receptor |
| ELK1 | ELK1, member of ETS oncogene family |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| EREG | epiregulin |
| FGA | fibrinogen alpha chain |
| FGB | fibrinogen beta chain |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGF3 | fibroblast growth factor 3 |
| FGF4 | fibroblast growth factor 4 |
| FGF5 | fibroblast growth factor 5 |
| FGF6 | fibroblast growth factor 6 |
| FGF7 | fibroblast growth factor 7 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FGF9 | fibroblast growth factor 9 |
| FGF10 | fibroblast growth factor 10 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FGG | fibrinogen gamma chain |
| FOXO1 | forkhead box O1 |
| FOXO3 | forkhead box O3 |
| FN1 | fibronectin 1 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GAB1 | GRB2-associated binding protein 1 |
| GRB2 | growth factor receptor-bound protein 2 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
