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FGFR4 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol FGFR4
Entrez Gene ID 2264
Full Name fibroblast growth factor receptor 4
Synonyms CD334,JTK2,TKF
General protein information
Preferred Names

fibroblast growth factor receptor 4

Names

fibroblast growth factor receptor 4
hydroxyaryl-protein kinase
protein-tyrosine kinase
tyrosine kinase related to fibroblast growth factor receptor
tyrosylprotein kinase

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

5

5q35.2

Disorder MIM:

134935

Disorder Html: {Cancer progression/metastasis} (3)

mRNA and Protein(s)

mRNA Protein Name
XM_011534464.2 XP_011532766.1 fibroblast growth factor receptor 4 isoform X1
XM_011534465.2 XP_011532767.1 fibroblast growth factor receptor 4 isoform X3
NM_213647.2 NP_998812.1 fibroblast growth factor receptor 4 isoform 1 precursor
NM_002011.4 NP_002002.3 fibroblast growth factor receptor 4 isoform 1 precursor
XM_005265838.3 XP_005265895.1 fibroblast growth factor receptor 4 isoform X2
NM_001291980.1 NP_001278909.1 fibroblast growth factor receptor 4 isoform 3 precursor
XM_005265838.2 XP_005265895.1 fibroblast growth factor receptor 4 isoform X1
NM_022963.3 NP_075252.2 fibroblast growth factor receptor 4 isoform 2 precursor



Homo sapiens (human) FGFR4 NP_002002.3
Canis lupus familiaris (dog) FGFR4 XP_005619229.1
Gallus gallus (chicken) FGFR4 XP_003642120.2
Pan troglodytes (chimpanzee) FGFR4 XP_518127.4
Bos taurus (cattle) FGFR4 NP_001179513.1
Mus musculus (house mouse) Fgfr4 NP_032037.2
Rattus norvegicus (Norway rat) Fgfr4 NP_001103374.1
Xenopus tropicalis (tropical clawed frog) fgfr4 NP_001016323.1
Danio rerio (zebrafish) fgfr4 NP_571505.1
Macaca mulatta (rhesus monkey) FGFR4 XP_001087243.1


Related articles in PubMed

Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea.
Johnston IM, Nolan JD, Pattni SS, Appleby RN, Zhang JH, Kennie SL, Madhan GK, Jameie-Oskooei S, Pathmasrirengam S, Lin J, Hong A, Dixon PH, Williamson C, Walters JR
The American journal of gastroenterology111(3)423-32(2016 Mar)

Silencing of FGFR4 could influence the biological features of gastric cancer cells and its therapeutic value in gastric cancer.
Ye Y, Jiang D, Li J, Wang M, Han C, Zhang X, Zhao C, Wen J, Kan Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(3)3185-95(2016 Mar)

A Polymorphism in the FGFR4 Gene Is Associated With Risk of Neuroblastoma and Altered Receptor Degradation.
Whittle SB, Reyes S, Du M, Gireud M, Zhang L, Woodfield SE, Ittmann M, Scheurer ME, Bean AJ, Zage PE
Journal of pediatric hematology/oncology38(2)131-8(2016 Mar)

Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site.
Ulaganathan VK, Sperl B, Rapp UR, Ullrich A
Nature528(7583)570-4(2015 Dec)

FGFR4 Is a Potential Predictive Biomarker in Oral and Oropharyngeal Squamous Cell Carcinoma.
Koole K, van Kempen PM, van Bockel LW, Smets T, van der Klooster Z, Dutman AC, Peeters T, Koole R, van Diest P, van Es RJ, Willems SM
Pathobiology : journal of immunopathology, molecular and cellular biology82(6)280-9(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These observations suggest a crucial role for cancer-associated fibroblasts and fibroblast growth factor-1/fibroblast growth factor receptor 4 signaling in the progression of ovarian cancer. the expression level of Snail1 and MMP3 was reduced, while the expression level of E-cadherin increased
Title: Cancer-associated fibroblasts secrete FGF-1 to promote ovarian proliferation, migration, and invasion through the activation of FGF-1/FGFR4 signaling.

High FGFR4 expression was significantly associated with the depth of invasion, lymph-node metastasis, pathological stage, and distant metastasis or recurrent disease in gastric cancer.
Title: Different clinical significance of FGFR1-4 expression between diffuse-type and intestinal-type gastric cancer.

Enhanced myocardial expression of FGFR4 is associated with left ventricular hypertrophy in chronic kidney disease.
Title: Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease.

The FGFR4 single-nucleotide polymorphism rs376618 had borderline significant differences in Patients With Primary Bile Acid Diarrhea.
Title: Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea.

Our study provides the first evidence of a role for FGFR4 in neuroblastoma
Title: A Polymorphism in the FGFR4 Gene Is Associated With Risk of Neuroblastoma and Altered Receptor Degradation.

The following FGFR4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGFR4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu27932 NM_002011.4
Latest version!
Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu27932 NM_213647.2
Latest version!
Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu27932 XM_005265838.3
Latest version!
Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu57776 XM_011534465.2
Latest version!
Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $391.30
$559.00
OHu27930 NM_022963.3
Latest version!
Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $538.30
$769.00
OHu27942 NM_001291980.1
Latest version!
Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu57775 XM_011534464.2
Latest version!
Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
View Old Accession Versions >>
OHu27932 XM_005265838.2 Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu27932
Clone ID Related Accession (Same CDS sequence) NM_213647.2 , NM_002011.4 , XM_005265838.3 , XM_005265838.2
Accession Version NM_213647.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2409bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM453707.1, BC011847.2 and AK225909.1. This sequence is a reference standard in the RefSeqGene project. On May 14, 2014 this sequence version replaced NM_213647.1. Transcript Variant: This variant (3) uses an alternative splice site for the first exon compared to variant 1. Both variants 1 and 3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011847.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_998812.1
CDS260..2668
Misc Feature(1)164..166
Misc Feature(2)386..610
Misc Feature(3)407..580
Misc Feature(4)728..982
Misc Feature(5)743..982
Misc Feature(6)1025..1309
Misc Feature(7)1049..1312
Misc Feature(8)order(1076..1078,1091..1099,1184..1189,1205..1207,1268..1270)
Misc Feature(9)1367..1429
Misc Feature(10)1619..2560
Misc Feature(11)1658..2488
Misc Feature(12)order(1676..1687,1694..1696,1700..1702,1760..1762,1766..1768,1859..1861,1907..1918,2093..2095,2105..2110,2114..2116,2144..2149)
Misc Feature(13)1976..1978
Misc Feature(14)2183..2185
Misc Feature(15)2186..2188
Misc Feature(16)2519..2521
Misc Feature(17)2519..2521
Exon (1)1..206
Exon (2)207..350
Exon (3)351..614
Exon (4)615..695
Exon (5)696..862
Exon (6)863..986
Exon (7)987..1177
Exon (8)1178..1316
Exon (9)1317..1510
Exon (10)1511..1656
Exon (11)1657..1778
Exon (12)1779..1889
Exon (13)1890..2080
Exon (14)2081..2203
Exon (15)2204..2274
Exon (16)2275..2412
Exon (17)2413..2518
Exon (18)2519..3134
Translation

Target ORF information:

RefSeq Version NM_213647.2
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_213647.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27932
Clone ID Related Accession (Same CDS sequence) NM_213647.2 , NM_002011.4 , XM_005265838.3 , XM_005265838.2
Accession Version NM_002011.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2409bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM453707.1, AK225909.1 and BC011847.2. On May 14, 2014 this sequence version replaced NM_002011.3. Transcript Variant: This variant (1) encodes the longest isoform (1), which contains a transmembrane domain, suggesting a membrane bound receptor. Variants 1 and 3 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225909.1, L03840.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002002.3
CDS216..2624
Misc Feature(1)342..566
Misc Feature(2)363..536
Misc Feature(3)684..938
Misc Feature(4)699..938
Misc Feature(5)981..1265
Misc Feature(6)1005..1268
Misc Feature(7)order(1032..1034,1047..1055,1140..1145,1161..1163,1224..1226)
Misc Feature(8)1323..1385
Misc Feature(9)1575..2516
Misc Feature(10)1614..2444
Misc Feature(11)order(1632..1643,1650..1652,1656..1658,1716..1718,1722..1724,1815..1817,1863..1874,2049..2051,2061..2066,2070..2072,2100..2105)
Misc Feature(12)1932..1934
Misc Feature(13)2139..2141
Misc Feature(14)2142..2144
Misc Feature(15)2475..2477
Misc Feature(16)2475..2477
Exon (1)1..162
Exon (2)163..306
Exon (3)307..570
Exon (4)571..651
Exon (5)652..818
Exon (6)819..942
Exon (7)943..1133
Exon (8)1134..1272
Exon (9)1273..1466
Exon (10)1467..1612
Exon (11)1613..1734
Exon (12)1735..1845
Exon (13)1846..2036
Exon (14)2037..2159
Exon (15)2160..2230
Exon (16)2231..2368
Exon (17)2369..2474
Exon (18)2475..3090
Translation

Target ORF information:

RefSeq Version NM_002011.4
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002011.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27932
Clone ID Related Accession (Same CDS sequence) NM_213647.2 , NM_002011.4 , XM_005265838.3 , XM_005265838.2
Accession Version XM_005265838.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2409bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005265838.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005265895.1
CDS168..2576
Misc Feature(1)294..518
Misc Feature(2)315..488
Misc Feature(3)636..890
Misc Feature(4)651..890
Misc Feature(5)933..1217
Misc Feature(6)957..1220
Misc Feature(7)order(984..986,999..1007,1092..1097,1113..1115,1176..1178)
Misc Feature(8)1527..2468
Misc Feature(9)1566..2396
Misc Feature(10)order(1584..1595,1602..1604,1608..1610,1668..1670,1674..1676,1767..1769,1815..1826,2001..2003,2013..2018,2022..2024,2052..2057)
Translation

Target ORF information:

RefSeq Version XM_005265838.3
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005265838.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27932
Clone ID Related Accession (Same CDS sequence) NM_213647.2 , NM_002011.4 , XM_005265838.3 , XM_005265838.2
Accession Version XM_005265838.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2409bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005265895.1
Translation

Target ORF information:

RefSeq Version XM_005265838.2
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005265838.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGGTA TACGGACATC ATCCTGTACG CGTCGGGCTC CCTGGCCTTG
GCTGTGCTCC TGCTGCTGGC CGGGCTGTAT CGAGGGCAGG CGCTCCACGG CCGGCACCCC
CGCCCGCCCG CCACTGTGCA GAAGCTCTCC CGCTTCCCTC TGGCCCGACA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu57776
Clone ID Related Accession (Same CDS sequence) XM_011534465.2
Accession Version XM_011534465.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2091bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534465.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGATCGTCC TGCAGAATCT CACCTTGATT ACAGGTGACT CCTTGACCTC CAGCAACGAT 
GATGAGGACC CCAAGTCCCA TAGGGACCCC TCGAATAGGC ACAGTTACCC CCAGCAAGCA
CCCTACTGGA CACACCCCCA GCGCATGGAG AAGAAACTGC ATGCAGTACC TGCGGGGAAC
ACCGTCAAGT TCCGCTGTCC AGCTGCAGGC AACCCCACGC CCACCATCCG CTGGCTTAAG
GATGGACAGG CCTTTCATGG GGAGAACCGC ATTGGAGGCA TTCGGCTGCG CCATCAGCAC
TGGAGTCTCG TGATGGAGAG CGTGGTGCCC TCGGACCGCG GCACATACAC CTGCCTGGTA
GAGAACGCTG TGGGCAGCAT CCGCTATAAC TACCTGCTAG ATGTGCTGGA GCGGTCCCCG
CACCGGCCCA TCCTGCAGGC CGGGCTCCCG GCCAACACCA CAGCCGTGGT GGGCAGCGAC
GTGGAGCTGC TGTGCAAGGT GTACAGCGAT GCCCAGCCCC ACATCCAGTG GCTGAAGCAC
ATCGTCATCA ACGGCAGCAG CTTCGGAGCC GACGGTTTCC CCTATGTGCA AGTCCTAAAG
ACTGCAGACA TCAATAGCTC AGAGGTGGAG GTCCTGTACC TGCGGAACGT GTCAGCCGAG
GACGCAGGCG AGTACACCTG CCTCGCAGGC AATTCCATCG GCCTCTCCTA CCAGTCTGCC
TGGCTCACGG TGCTGCCAGA GGAGGACCCC ACATGGACCG CAGCAGCGCC CGAGGCCAGG
TATACGGACA TCATCCTGTA CGCGTCGGGC TCCCTGGCCT TGGCTGTGCT CCTGCTGCTG
GCCGGGCTGT ATCGAGGGCA GGCGCTCCAC GGCCGGCACC CCCGCCCGCC CGCCACTGTG
CAGAAGCTCT CCCGCTTCCC TCTGGCCCGA CAGTTCTCCC TGGAGTCAGG CTCTTCCGGC
AAGTCAAGCT CATCCCTGGT ACGAGGCGTG CGTCTCTCCT CCAGCGGCCC CGCCTTGCTC
GCCGGCCTCG TGAGTCTAGA TCTACCTCTC GACCCACTAT GGGAGTTCCC CCGGGACAGG
CTGGTGCTTG GGAAGCCCCT AGGCGAGGGC TGCTTTGGCC AGGTAGTACG TGCAGAGGCC
TTTGGCATGG ACCCTGCCCG GCCTGACCAA GCCAGCACTG TGGCCGTCAA GATGCTCAAA
GACAACGCCT CTGACAAGGA CCTGGCCGAC CTGGTCTCGG AGATGGAGGT GATGAAGCTG
ATCGGCCGAC ACAAGAACAT CATCAACCTG CTTGGTGTCT GCACCCAGGA AGGGCCCCTG
TACGTGATCG TGGAGTGCGC CGCCAAGGGA AACCTGCGGG AGTTCCTGCG GGCCCGGCGC
CCCCCAGGCC CCGACCTCAG CCCCGACGGT CCTCGGAGCA GTGAGGGGCC GCTCTCCTTC
CCAGTCCTGG TCTCCTGCGC CTACCAGGTG GCCCGAGGCA TGCAGTATCT GGAGTCCCGG
AAGTGTATCC ACCGGGACCT GGCTGCCCGC AATGTGCTGG TGACTGAGGA CAATGTGATG
AAGATTGCTG ACTTTGGGCT GGCCCGCGGC GTCCACCACA TTGACTACTA TAAGAAAACC
AGCAACGGCC GCCTGCCTGT GAAGTGGATG GCGCCCGAGG CCTTGTTTGA CCGGGTGTAC
ACACACCAGA GTGACGTGTG GTCTTTTGGG ATCCTGCTAT GGGAGATCTT CACCCTCGGG
GGCTCCCCGT ATCCTGGCAT CCCGGTGGAG GAGCTGTTCT CGCTGCTGCG GGAGGGACAT
CGGATGGACC GACCCCCACA CTGCCCCCCA GAGCTGTACG GGCTGATGCG TGAGTGCTGG
CACGCAGCGC CCTCCCAGAG GCCTACCTTC AAGCAGCTGG TGGAGGCGCT GGACAAGGTC
CTGCTGGCCG TCTCTGAGGA GTACCTCGAC CTCCGCCTGA CCTTCGGACC CTATTCCCCC
TCTGGTGGGG ACGCCAGCAG CACCTGCTCC TCCAGCGATT CTGTCTTCAG CCACGACCCC
CTGCCATTGG GATCCAGCTC CTTCCCCTTC GGGTCTGGGG TGCAGACATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011532767.1
CDS571..2661
Misc Feature(1)721..975
Misc Feature(2)736..975
Misc Feature(3)1018..1302
Misc Feature(4)1042..1305
Misc Feature(5)order(1069..1071,1084..1092,1177..1182,1198..1200,1261..1263)
Misc Feature(6)1612..2553
Misc Feature(7)1651..2481
Misc Feature(8)order(1669..1680,1687..1689,1693..1695,1753..1755,1759..1761,1852..1854,1900..1911,2086..2088,2098..2103,2107..2109,2137..2142)
Translation

Target ORF information:

RefSeq Version XM_011534465.2
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011534465.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGATCGTCC TGCAGAATCT CACCTTGATT ACAGGTGACT CCTTGACCTC CAGCAACGAT 
GATGAGGACC CCAAGTCCCA TAGGGACCCC TCGAATAGGC ACAGTTACCC CCAGCAAGCA
CCCTACTGGA CACACCCCCA GCGCATGGAG AAGAAACTGC ATGCAGTACC TGCGGGGAAC
ACCGTCAAGT TCCGCTGTCC AGCTGCAGGC AACCCCACGC CCACCATCCG CTGGCTTAAG
GATGGACAGG CCTTTCATGG GGAGAACCGC ATTGGAGGCA TTCGGCTGCG CCATCAGCAC
TGGAGTCTCG TGATGGAGAG CGTGGTGCCC TCGGACCGCG GCACATACAC CTGCCTGGTA
GAGAACGCTG TGGGCAGCAT CCGCTATAAC TACCTGCTAG ATGTGCTGGA GCGGTCCCCG
CACCGGCCCA TCCTGCAGGC CGGGCTCCCG GCCAACACCA CAGCCGTGGT GGGCAGCGAC
GTGGAGCTGC TGTGCAAGGT GTACAGCGAT GCCCAGCCCC ACATCCAGTG GCTGAAGCAC
ATCGTCATCA ACGGCAGCAG CTTCGGAGCC GACGGTTTCC CCTATGTGCA AGTCCTAAAG
ACTGCAGACA TCAATAGCTC AGAGGTGGAG GTCCTGTACC TGCGGAACGT GTCAGCCGAG
GACGCAGGCG AGTACACCTG CCTCGCAGGC AATTCCATCG GCCTCTCCTA CCAGTCTGCC
TGGCTCACGG TGCTGCCAGA GGAGGACCCC ACATGGACCG CAGCAGCGCC CGAGGCCAGG
TATACGGACA TCATCCTGTA CGCGTCGGGC TCCCTGGCCT TGGCTGTGCT CCTGCTGCTG
GCCGGGCTGT ATCGAGGGCA GGCGCTCCAC GGCCGGCACC CCCGCCCGCC CGCCACTGTG
CAGAAGCTCT CCCGCTTCCC TCTGGCCCGA CAGTTCTCCC TGGAGTCAGG CTCTTCCGGC
AAGTCAAGCT CATCCCTGGT ACGAGGCGTG CGTCTCTCCT CCAGCGGCCC CGCCTTGCTC
GCCGGCCTCG TGAGTCTAGA TCTACCTCTC GACCCACTAT GGGAGTTCCC CCGGGACAGG
CTGGTGCTTG GGAAGCCCCT AGGCGAGGGC TGCTTTGGCC AGGTAGTACG TGCAGAGGCC
TTTGGCATGG ACCCTGCCCG GCCTGACCAA GCCAGCACTG TGGCCGTCAA GATGCTCAAA
GACAACGCCT CTGACAAGGA CCTGGCCGAC CTGGTCTCGG AGATGGAGGT GATGAAGCTG
ATCGGCCGAC ACAAGAACAT CATCAACCTG CTTGGTGTCT GCACCCAGGA AGGGCCCCTG
TACGTGATCG TGGAGTGCGC CGCCAAGGGA AACCTGCGGG AGTTCCTGCG GGCCCGGCGC
CCCCCAGGCC CCGACCTCAG CCCCGACGGT CCTCGGAGCA GTGAGGGGCC GCTCTCCTTC
CCAGTCCTGG TCTCCTGCGC CTACCAGGTG GCCCGAGGCA TGCAGTATCT GGAGTCCCGG
AAGTGTATCC ACCGGGACCT GGCTGCCCGC AATGTGCTGG TGACTGAGGA CAATGTGATG
AAGATTGCTG ACTTTGGGCT GGCCCGCGGC GTCCACCACA TTGACTACTA TAAGAAAACC
AGCAACGGCC GCCTGCCTGT GAAGTGGATG GCGCCCGAGG CCTTGTTTGA CCGGGTGTAC
ACACACCAGA GTGACGTGTG GTCTTTTGGG ATCCTGCTAT GGGAGATCTT CACCCTCGGG
GGCTCCCCGT ATCCTGGCAT CCCGGTGGAG GAGCTGTTCT CGCTGCTGCG GGAGGGACAT
CGGATGGACC GACCCCCACA CTGCCCCCCA GAGCTGTACG GGCTGATGCG TGAGTGCTGG
CACGCAGCGC CCTCCCAGAG GCCTACCTTC AAGCAGCTGG TGGAGGCGCT GGACAAGGTC
CTGCTGGCCG TCTCTGAGGA GTACCTCGAC CTCCGCCTGA CCTTCGGACC CTATTCCCCC
TCTGGTGGGG ACGCCAGCAG CACCTGCTCC TCCAGCGATT CTGTCTTCAG CCACGACCCC
CTGCCATTGG GATCCAGCTC CTTCCCCTTC GGGTCTGGGG TGCAGACATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27930
Clone ID Related Accession (Same CDS sequence) NM_022963.3
Accession Version NM_022963.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2289bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011847.2, AF202063.1 and AK225909.1. On May 14, 2014 this sequence version replaced NM_022963.2. Transcript Variant: This variant (2) lacks an internal exon but has an alternate segment in the central coding region, compared to variant 1. The resulting isoform (2) has a distinct and shorter internal segment, compared to isoform 1, and it is missing the transmembrane region, suggesting a soluble rather than membrane-bound receptor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF202063.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGGTA CTGGGCGCAT CCCCCACCTC
ACATGTGACA GCCTGACTCC AGCAGGCAGA ACCAAGTCTC CCACTTTGCA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_075252.2
CDS54..2342
Misc Feature(1)180..404
Misc Feature(2)201..374
Misc Feature(3)522..776
Misc Feature(4)537..776
Misc Feature(5)819..1103
Misc Feature(6)843..1106
Misc Feature(7)order(870..872,885..893,978..983,999..1001,1062..1064)
Misc Feature(8)1293..2234
Misc Feature(9)1332..2162
Misc Feature(10)order(1350..1361,1368..1370,1374..1376,1434..1436,1440..1442,1533..1535,1581..1592,1767..1769,1779..1784,1788..1790,1818..1823)
Misc Feature(11)2193..2195
Exon (1)1..144
Exon (2)145..408
Exon (3)409..489
Exon (4)490..656
Exon (5)657..780
Exon (6)781..971
Exon (7)972..1110
Exon (8)1111..1330
Exon (9)1331..1452
Exon (10)1453..1563
Exon (11)1564..1754
Exon (12)1755..1877
Exon (13)1878..1948
Exon (14)1949..2086
Exon (15)2087..2192
Exon (16)2193..2808
Translation

Target ORF information:

RefSeq Version NM_022963.3
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022963.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGGTA CTGGGCGCAT CCCCCACCTC
ACATGTGACA GCCTGACTCC AGCAGGCAGA ACCAAGTCTC CCACTTTGCA GTTCTCCCTG
GAGTCAGGCT CTTCCGGCAA GTCAAGCTCA TCCCTGGTAC GAGGCGTGCG TCTCTCCTCC
AGCGGCCCCG CCTTGCTCGC CGGCCTCGTG AGTCTAGATC TACCTCTCGA CCCACTATGG
GAGTTCCCCC GGGACAGGCT GGTGCTTGGG AAGCCCCTAG GCGAGGGCTG CTTTGGCCAG
GTAGTACGTG CAGAGGCCTT TGGCATGGAC CCTGCCCGGC CTGACCAAGC CAGCACTGTG
GCCGTCAAGA TGCTCAAAGA CAACGCCTCT GACAAGGACC TGGCCGACCT GGTCTCGGAG
ATGGAGGTGA TGAAGCTGAT CGGCCGACAC AAGAACATCA TCAACCTGCT TGGTGTCTGC
ACCCAGGAAG GGCCCCTGTA CGTGATCGTG GAGTGCGCCG CCAAGGGAAA CCTGCGGGAG
TTCCTGCGGG CCCGGCGCCC CCCAGGCCCC GACCTCAGCC CCGACGGTCC TCGGAGCAGT
GAGGGGCCGC TCTCCTTCCC AGTCCTGGTC TCCTGCGCCT ACCAGGTGGC CCGAGGCATG
CAGTATCTGG AGTCCCGGAA GTGTATCCAC CGGGACCTGG CTGCCCGCAA TGTGCTGGTG
ACTGAGGACA ATGTGATGAA GATTGCTGAC TTTGGGCTGG CCCGCGGCGT CCACCACATT
GACTACTATA AGAAAACCAG CAACGGCCGC CTGCCTGTGA AGTGGATGGC GCCCGAGGCC
TTGTTTGACC GGGTGTACAC ACACCAGAGT GACGTGTGGT CTTTTGGGAT CCTGCTATGG
GAGATCTTCA CCCTCGGGGG CTCCCCGTAT CCTGGCATCC CGGTGGAGGA GCTGTTCTCG
CTGCTGCGGG AGGGACATCG GATGGACCGA CCCCCACACT GCCCCCCAGA GCTGTACGGG
CTGATGCGTG AGTGCTGGCA CGCAGCGCCC TCCCAGAGGC CTACCTTCAA GCAGCTGGTG
GAGGCGCTGG ACAAGGTCCT GCTGGCCGTC TCTGAGGAGT ACCTCGACCT CCGCCTGACC
TTCGGACCCT ATTCCCCCTC TGGTGGGGAC GCCAGCAGCA CCTGCTCCTC CAGCGATTCT
GTCTTCAGCC ACGACCCCCT GCCATTGGGA TCCAGCTCCT TCCCCTTCGG GTCTGGGGTG
CAGACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27942
Clone ID Related Accession (Same CDS sequence) NM_001291980.1
Accession Version NM_001291980.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2205bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM453707.1, AK301169.1, BC011847.2 and AK225909.1. Transcript Variant: This variant (4) has two alternate splice sites in the coding region, compared to variant 1. The resulting isoform (3) has a distinct and shorter internal segment, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGTTC TCCCTGGAGT CAGGCTCTTC CGGCAAGTCA AGCTCATCCC
TGGTACGAGG CGTGCGTCTC TCCTCCAGCG GCCCCGCCTT GCTCGCCGGC CTCGCTGGTG
CTTGGGAAGC CCCTAGGCGA GGGCTGCTTT GGCCAGGTAG TACGTGCAGA GGCCTTTGGC
ATGGACCCTG CCCGGCCTGA CCAAGCCAGC ACTGTGGCCG TCAAGATGCT CAAAGACAAC
GCCTCTGACA AGGACCTGGC CGACCTGGTC TCGGAGATGG AGGTGATGAA GCTGATCGGC
CGACACAAGA ACATCATCAA CCTGCTTGGT GTCTGCACCC AGGAAGGGCC CCTGTACGTG
ATCGTGGAGT GCGCCGCCAA GGGAAACCTG CGGGAGTTCC TGCGGGCCCG GCGCCCCCCA
GGCCCCGACC TCAGCCCCGA CGGTCCTCGG AGCAGTGAGG GGCCGCTCTC CTTCCCAGTC
CTGGTCTCCT GCGCCTACCA GGTGGCCCGA GGCATGCAGT ATCTGGAGTC CCGGAAGTGT
ATCCACCGGG ACCTGGCTGC CCGCAATGTG CTGGTGACTG AGGACAATGT GATGAAGATT
GCTGACTTTG GGCTGGCCCG CGGCGTCCAC CACATTGACT ACTATAAGAA AACCAGCAAC
GGCCGCCTGC CTGTGAAGTG GATGGCGCCC GAGGCCTTGT TTGACCGGGT GTACACACAC
CAGAGTGACG TGTGGTCTTT TGGGATCCTG CTATGGGAGA TCTTCACCCT CGGGGGCTCC
CCGTATCCTG GCATCCCGGT GGAGGAGCTG TTCTCGCTGC TGCGGGAGGG ACATCGGATG
GACCGACCCC CACACTGCCC CCCAGAGCTG TACGGGCTGA TGCGTGAGTG CTGGCACGCA
GCGCCCTCCC AGAGGCCTAC CTTCAAGCAG CTGGTGGAGG CGCTGGACAA GGTCCTGCTG
GCCGTCTCTG AGGAGTACCT CGACCTCCGC CTGACCTTCG GACCCTATTC CCCCTCTGGT
GGGGACGCCA GCAGCACCTG CTCCTCCAGC GATTCTGTCT TCAGCCACGA CCCCCTGCCA
TTGGGATCCA GCTCCTTCCC CTTCGGGTCT GGGGTGCAGA CATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278909.1
CDS216..2420
Misc Feature(1)342..566
Misc Feature(2)363..536
Misc Feature(3)684..938
Misc Feature(4)699..938
Misc Feature(5)981..1265
Misc Feature(6)1005..1268
Misc Feature(7)order(1032..1034,1047..1055,1140..1145,1161..1163,1224..1226)
Misc Feature(8)1410..2312
Misc Feature(9)1410..2240
Misc Feature(10)order(1428..1439,1446..1448,1452..1454,1512..1514,1518..1520,1611..1613,1659..1670,1845..1847,1857..1862,1866..1868,1896..1901)
Exon (1)1..162
Exon (2)163..306
Exon (3)307..570
Exon (4)571..651
Exon (5)652..818
Exon (6)819..942
Exon (7)943..1133
Exon (8)1134..1272
Exon (9)1273..1312
Exon (10)1313..1408
Exon (11)1409..1530
Exon (12)1531..1641
Exon (13)1642..1832
Exon (14)1833..1955
Exon (15)1956..2026
Exon (16)2027..2164
Exon (17)2165..2270
Exon (18)2271..2886
Translation

Target ORF information:

RefSeq Version NM_001291980.1
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291980.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCGGCTGC TGCTGGCCCT GTTGGGGGTC CTGCTGAGTG TGCCTGGGCC TCCAGTCTTG 
TCCCTGGAGG CCTCTGAGGA AGTGGAGCTT GAGCCCTGCC TGGCTCCCAG CCTGGAGCAG
CAAGAGCAGG AGCTGACAGT AGCCCTTGGG CAGCCTGTGC GTCTGTGCTG TGGGCGGGCT
GAGCGTGGTG GCCACTGGTA CAAGGAGGGC AGTCGCCTGG CACCTGCTGG CCGTGTACGG
GGCTGGAGGG GCCGCCTAGA GATTGCCAGC TTCCTACCTG AGGATGCTGG CCGCTACCTC
TGCCTGGCAC GAGGCTCCAT GATCGTCCTG CAGAATCTCA CCTTGATTAC AGGTGACTCC
TTGACCTCCA GCAACGATGA TGAGGACCCC AAGTCCCATA GGGACCCCTC GAATAGGCAC
AGTTACCCCC AGCAAGCACC CTACTGGACA CACCCCCAGC GCATGGAGAA GAAACTGCAT
GCAGTACCTG CGGGGAACAC CGTCAAGTTC CGCTGTCCAG CTGCAGGCAA CCCCACGCCC
ACCATCCGCT GGCTTAAGGA TGGACAGGCC TTTCATGGGG AGAACCGCAT TGGAGGCATT
CGGCTGCGCC ATCAGCACTG GAGTCTCGTG ATGGAGAGCG TGGTGCCCTC GGACCGCGGC
ACATACACCT GCCTGGTAGA GAACGCTGTG GGCAGCATCC GCTATAACTA CCTGCTAGAT
GTGCTGGAGC GGTCCCCGCA CCGGCCCATC CTGCAGGCCG GGCTCCCGGC CAACACCACA
GCCGTGGTGG GCAGCGACGT GGAGCTGCTG TGCAAGGTGT ACAGCGATGC CCAGCCCCAC
ATCCAGTGGC TGAAGCACAT CGTCATCAAC GGCAGCAGCT TCGGAGCCGA CGGTTTCCCC
TATGTGCAAG TCCTAAAGAC TGCAGACATC AATAGCTCAG AGGTGGAGGT CCTGTACCTG
CGGAACGTGT CAGCCGAGGA CGCAGGCGAG TACACCTGCC TCGCAGGCAA TTCCATCGGC
CTCTCCTACC AGTCTGCCTG GCTCACGGTG CTGCCAGAGG AGGACCCCAC ATGGACCGCA
GCAGCGCCCG AGGCCAGTTC TCCCTGGAGT CAGGCTCTTC CGGCAAGTCA AGCTCATCCC
TGGTACGAGG CGTGCGTCTC TCCTCCAGCG GCCCCGCCTT GCTCGCCGGC CTCGCTGGTG
CTTGGGAAGC CCCTAGGCGA GGGCTGCTTT GGCCAGGTAG TACGTGCAGA GGCCTTTGGC
ATGGACCCTG CCCGGCCTGA CCAAGCCAGC ACTGTGGCCG TCAAGATGCT CAAAGACAAC
GCCTCTGACA AGGACCTGGC CGACCTGGTC TCGGAGATGG AGGTGATGAA GCTGATCGGC
CGACACAAGA ACATCATCAA CCTGCTTGGT GTCTGCACCC AGGAAGGGCC CCTGTACGTG
ATCGTGGAGT GCGCCGCCAA GGGAAACCTG CGGGAGTTCC TGCGGGCCCG GCGCCCCCCA
GGCCCCGACC TCAGCCCCGA CGGTCCTCGG AGCAGTGAGG GGCCGCTCTC CTTCCCAGTC
CTGGTCTCCT GCGCCTACCA GGTGGCCCGA GGCATGCAGT ATCTGGAGTC CCGGAAGTGT
ATCCACCGGG ACCTGGCTGC CCGCAATGTG CTGGTGACTG AGGACAATGT GATGAAGATT
GCTGACTTTG GGCTGGCCCG CGGCGTCCAC CACATTGACT ACTATAAGAA AACCAGCAAC
GGCCGCCTGC CTGTGAAGTG GATGGCGCCC GAGGCCTTGT TTGACCGGGT GTACACACAC
CAGAGTGACG TGTGGTCTTT TGGGATCCTG CTATGGGAGA TCTTCACCCT CGGGGGCTCC
CCGTATCCTG GCATCCCGGT GGAGGAGCTG TTCTCGCTGC TGCGGGAGGG ACATCGGATG
GACCGACCCC CACACTGCCC CCCAGAGCTG TACGGGCTGA TGCGTGAGTG CTGGCACGCA
GCGCCCTCCC AGAGGCCTAC CTTCAAGCAG CTGGTGGAGG CGCTGGACAA GGTCCTGCTG
GCCGTCTCTG AGGAGTACCT CGACCTCCGC CTGACCTTCG GACCCTATTC CCCCTCTGGT
GGGGACGCCA GCAGCACCTG CTCCTCCAGC GATTCTGTCT TCAGCCACGA CCCCCTGCCA
TTGGGATCCA GCTCCTTCCC CTTCGGGTCT GGGGTGCAGA CATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu57775
Clone ID Related Accession (Same CDS sequence) XM_011534464.2
Accession Version XM_011534464.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2502bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor 4 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534464.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGGACTGGA AGTGGAGTGG CAGTGACCAA GGAGGAGGAG GAAGGCAGTT GGTGGGAAGT 
CCAGCTTGGG TCCCTGAGAG CTGTGAGAAG GAGATGCGGC TGCTGCTGGC CCTGTTGGGG
GTCCTGCTGA GTGTGCCTGG GCCTCCAGTC TTGTCCCTGG AGGCCTCTGA GGAAGTGGAG
CTTGAGCCCT GCCTGGCTCC CAGCCTGGAG CAGCAAGAGC AGGAGCTGAC AGTAGCCCTT
GGGCAGCCTG TGCGTCTGTG CTGTGGGCGG GCTGAGCGTG GTGGCCACTG GTACAAGGAG
GGCAGTCGCC TGGCACCTGC TGGCCGTGTA CGGGGCTGGA GGGGCCGCCT AGAGATTGCC
AGCTTCCTAC CTGAGGATGC TGGCCGCTAC CTCTGCCTGG CACGAGGCTC CATGATCGTC
CTGCAGAATC TCACCTTGAT TACAGGTGAC TCCTTGACCT CCAGCAACGA TGATGAGGAC
CCCAAGTCCC ATAGGGACCC CTCGAATAGG CACAGTTACC CCCAGCAAGC ACCCTACTGG
ACACACCCCC AGCGCATGGA GAAGAAACTG CATGCAGTAC CTGCGGGGAA CACCGTCAAG
TTCCGCTGTC CAGCTGCAGG CAACCCCACG CCCACCATCC GCTGGCTTAA GGATGGACAG
GCCTTTCATG GGGAGAACCG CATTGGAGGC ATTCGGCTGC GCCATCAGCA CTGGAGTCTC
GTGATGGAGA GCGTGGTGCC CTCGGACCGC GGCACATACA CCTGCCTGGT AGAGAACGCT
GTGGGCAGCA TCCGCTATAA CTACCTGCTA GATGTGCTGG AGCGGTCCCC GCACCGGCCC
ATCCTGCAGG CCGGGCTCCC GGCCAACACC ACAGCCGTGG TGGGCAGCGA CGTGGAGCTG
CTGTGCAAGG TGTACAGCGA TGCCCAGCCC CACATCCAGT GGCTGAAGCA CATCGTCATC
AACGGCAGCA GCTTCGGAGC CGACGGTTTC CCCTATGTGC AAGTCCTAAA GACTGCAGAC
ATCAATAGCT CAGAGGTGGA GGTCCTGTAC CTGCGGAACG TGTCAGCCGA GGACGCAGGC
GAGTACACCT GCCTCGCAGG CAATTCCATC GGCCTCTCCT ACCAGTCTGC CTGGCTCACG
GTGCTGCCAG AGGAGGACCC CACATGGACC GCAGCAGCGC CCGAGGCCAG GTATACGGAC
ATCATCCTGT ACGCGTCGGG CTCCCTGGCC TTGGCTGTGC TCCTGCTGCT GGCCGGGCTG
TATCGAGGGC AGGCGCTCCA CGGCCGGCAC CCCCGCCCGC CCGCCACTGT GCAGAAGCTC
TCCCGCTTCC CTCTGGCCCG ACAGTTCTCC CTGGAGTCAG GCTCTTCCGG CAAGTCAAGC
TCATCCCTGG TACGAGGCGT GCGTCTCTCC TCCAGCGGCC CCGCCTTGCT CGCCGGCCTC
GTGAGTCTAG ATCTACCTCT CGACCCACTA TGGGAGTTCC CCCGGGACAG GCTGGTGCTT
GGGAAGCCCC TAGGCGAGGG CTGCTTTGGC CAGGTAGTAC GTGCAGAGGC CTTTGGCATG
GACCCTGCCC GGCCTGACCA AGCCAGCACT GTGGCCGTCA AGATGCTCAA AGACAACGCC
TCTGACAAGG ACCTGGCCGA CCTGGTCTCG GAGATGGAGG TGATGAAGCT GATCGGCCGA
CACAAGAACA TCATCAACCT GCTTGGTGTC TGCACCCAGG AAGGGCCCCT GTACGTGATC
GTGGAGTGCG CCGCCAAGGG AAACCTGCGG GAGTTCCTGC GGGCCCGGCG CCCCCCAGGC
CCCGACCTCA GCCCCGACGG TCCTCGGAGC AGTGAGGGGC CGCTCTCCTT CCCAGTCCTG
GTCTCCTGCG CCTACCAGGT GGCCCGAGGC ATGCAGTATC TGGAGTCCCG GAAGTGTATC
CACCGGGACC TGGCTGCCCG CAATGTGCTG GTGACTGAGG ACAATGTGAT GAAGATTGCT
GACTTTGGGC TGGCCCGCGG CGTCCACCAC ATTGACTACT ATAAGAAAAC CAGCAACGGC
CGCCTGCCTG TGAAGTGGAT GGCGCCCGAG GCCTTGTTTG ACCGGGTGTA CACACACCAG
AGTGACGTGT GGTCTTTTGG GATCCTGCTA TGGGAGATCT TCACCCTCGG GGGCTCCCCG
TATCCTGGCA TCCCGGTGGA GGAGCTGTTC TCGCTGCTGC GGGAGGGACA TCGGATGGAC
CGACCCCCAC ACTGCCCCCC AGAGCTGTAC GGGCTGATGC GTGAGTGCTG GCACGCAGCG
CCCTCCCAGA GGCCTACCTT CAAGCAGCTG GTGGAGGCGC TGGACAAGGT CCTGCTGGCC
GTCTCTGAGG AGTACCTCGA CCTCCGCCTG ACCTTCGGAC CCTATTCCCC CTCTGGTGGG
GACGCCAGCA GCACCTGCTC CTCCAGCGAT TCTGTCTTCA GCCACGACCC CCTGCCATTG
GGATCCAGCT CCTTCCCCTT CGGGTCTGGG GTGCAGACAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011532766.1
CDS237..2738
Misc Feature(1)456..680
Misc Feature(2)477..650
Misc Feature(3)798..1052
Misc Feature(4)813..1052
Misc Feature(5)1095..1379
Misc Feature(6)1119..1382
Misc Feature(7)order(1146..1148,1161..1169,1254..1259,1275..1277,1338..1340)
Misc Feature(8)1689..2630
Misc Feature(9)1728..2558
Misc Feature(10)order(1746..1757,1764..1766,1770..1772,1830..1832,1836..1838,1929..1931,1977..1988,2163..2165,2175..2180,2184..2186,2214..2219)
Translation

Target ORF information:

RefSeq Version XM_011534464.2
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011534464.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGGACTGGA AGTGGAGTGG CAGTGACCAA GGAGGAGGAG GAAGGCAGTT GGTGGGAAGT 
CCAGCTTGGG TCCCTGAGAG CTGTGAGAAG GAGATGCGGC TGCTGCTGGC CCTGTTGGGG
GTCCTGCTGA GTGTGCCTGG GCCTCCAGTC TTGTCCCTGG AGGCCTCTGA GGAAGTGGAG
CTTGAGCCCT GCCTGGCTCC CAGCCTGGAG CAGCAAGAGC AGGAGCTGAC AGTAGCCCTT
GGGCAGCCTG TGCGTCTGTG CTGTGGGCGG GCTGAGCGTG GTGGCCACTG GTACAAGGAG
GGCAGTCGCC TGGCACCTGC TGGCCGTGTA CGGGGCTGGA GGGGCCGCCT AGAGATTGCC
AGCTTCCTAC CTGAGGATGC TGGCCGCTAC CTCTGCCTGG CACGAGGCTC CATGATCGTC
CTGCAGAATC TCACCTTGAT TACAGGTGAC TCCTTGACCT CCAGCAACGA TGATGAGGAC
CCCAAGTCCC ATAGGGACCC CTCGAATAGG CACAGTTACC CCCAGCAAGC ACCCTACTGG
ACACACCCCC AGCGCATGGA GAAGAAACTG CATGCAGTAC CTGCGGGGAA CACCGTCAAG
TTCCGCTGTC CAGCTGCAGG CAACCCCACG CCCACCATCC GCTGGCTTAA GGATGGACAG
GCCTTTCATG GGGAGAACCG CATTGGAGGC ATTCGGCTGC GCCATCAGCA CTGGAGTCTC
GTGATGGAGA GCGTGGTGCC CTCGGACCGC GGCACATACA CCTGCCTGGT AGAGAACGCT
GTGGGCAGCA TCCGCTATAA CTACCTGCTA GATGTGCTGG AGCGGTCCCC GCACCGGCCC
ATCCTGCAGG CCGGGCTCCC GGCCAACACC ACAGCCGTGG TGGGCAGCGA CGTGGAGCTG
CTGTGCAAGG TGTACAGCGA TGCCCAGCCC CACATCCAGT GGCTGAAGCA CATCGTCATC
AACGGCAGCA GCTTCGGAGC CGACGGTTTC CCCTATGTGC AAGTCCTAAA GACTGCAGAC
ATCAATAGCT CAGAGGTGGA GGTCCTGTAC CTGCGGAACG TGTCAGCCGA GGACGCAGGC
GAGTACACCT GCCTCGCAGG CAATTCCATC GGCCTCTCCT ACCAGTCTGC CTGGCTCACG
GTGCTGCCAG AGGAGGACCC CACATGGACC GCAGCAGCGC CCGAGGCCAG GTATACGGAC
ATCATCCTGT ACGCGTCGGG CTCCCTGGCC TTGGCTGTGC TCCTGCTGCT GGCCGGGCTG
TATCGAGGGC AGGCGCTCCA CGGCCGGCAC CCCCGCCCGC CCGCCACTGT GCAGAAGCTC
TCCCGCTTCC CTCTGGCCCG ACAGTTCTCC CTGGAGTCAG GCTCTTCCGG CAAGTCAAGC
TCATCCCTGG TACGAGGCGT GCGTCTCTCC TCCAGCGGCC CCGCCTTGCT CGCCGGCCTC
GTGAGTCTAG ATCTACCTCT CGACCCACTA TGGGAGTTCC CCCGGGACAG GCTGGTGCTT
GGGAAGCCCC TAGGCGAGGG CTGCTTTGGC CAGGTAGTAC GTGCAGAGGC CTTTGGCATG
GACCCTGCCC GGCCTGACCA AGCCAGCACT GTGGCCGTCA AGATGCTCAA AGACAACGCC
TCTGACAAGG ACCTGGCCGA CCTGGTCTCG GAGATGGAGG TGATGAAGCT GATCGGCCGA
CACAAGAACA TCATCAACCT GCTTGGTGTC TGCACCCAGG AAGGGCCCCT GTACGTGATC
GTGGAGTGCG CCGCCAAGGG AAACCTGCGG GAGTTCCTGC GGGCCCGGCG CCCCCCAGGC
CCCGACCTCA GCCCCGACGG TCCTCGGAGC AGTGAGGGGC CGCTCTCCTT CCCAGTCCTG
GTCTCCTGCG CCTACCAGGT GGCCCGAGGC ATGCAGTATC TGGAGTCCCG GAAGTGTATC
CACCGGGACC TGGCTGCCCG CAATGTGCTG GTGACTGAGG ACAATGTGAT GAAGATTGCT
GACTTTGGGC TGGCCCGCGG CGTCCACCAC ATTGACTACT ATAAGAAAAC CAGCAACGGC
CGCCTGCCTG TGAAGTGGAT GGCGCCCGAG GCCTTGTTTG ACCGGGTGTA CACACACCAG
AGTGACGTGT GGTCTTTTGG GATCCTGCTA TGGGAGATCT TCACCCTCGG GGGCTCCCCG
TATCCTGGCA TCCCGGTGGA GGAGCTGTTC TCGCTGCTGC GGGAGGGACA TCGGATGGAC
CGACCCCCAC ACTGCCCCCC AGAGCTGTAC GGGCTGATGC GTGAGTGCTG GCACGCAGCG
CCCTCCCAGA GGCCTACCTT CAAGCAGCTG GTGGAGGCGC TGGACAAGGT CCTGCTGGCC
GTCTCTGAGG AGTACCTCGA CCTCCGCCTG ACCTTCGGAC CCTATTCCCC CTCTGGTGGG
GACGCCAGCA GCACCTGCTC CTCCAGCGAT TCTGTCTTCA GCCACGACCC CCTGCCATTG
GGATCCAGCT CCTTCCCCTT CGGGTCTGGG GTGCAGACAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea.
The American journal of gastroenterology111(3)423-32(2016 Mar)
Johnston IM,Nolan JD,Pattni SS,Appleby RN,Zhang JH,Kennie SL,Madhan GK,Jameie-Oskooei S,Pathmasrirengam S,Lin J,Hong A,Dixon PH,Williamson C,Walters JR


book

Silencing of FGFR4 could influence the biological features of gastric cancer cells and its therapeutic value in gastric cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(3)3185-95(2016 Mar)
Ye Y,Jiang D,Li J,Wang M,Han C,Zhang X,Zhao C,Wen J,Kan Q


book

A Polymorphism in the FGFR4 Gene Is Associated With Risk of Neuroblastoma and Altered Receptor Degradation.
Journal of pediatric hematology/oncology38(2)131-8(2016 Mar)
Whittle SB,Reyes S,Du M,Gireud M,Zhang L,Woodfield SE,Ittmann M,Scheurer ME,Bean AJ,Zage PE


book

Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site.
Nature528(7583)570-4(2015 Dec)
Ulaganathan VK,Sperl B,Rapp UR,Ullrich A


book

FGFR4 Is a Potential Predictive Biomarker in Oral and Oropharyngeal Squamous Cell Carcinoma.
Pathobiology : journal of immunopathology, molecular and cellular biology82(6)280-9(2015)
Koole K,van Kempen PM,van Bockel LW,Smets T,van der Klooster Z,Dutman AC,Peeters T,Koole R,van Diest P,van Es RJ,Willems SM


 
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