About the Fc epsilon receptor (FCERI) signaling pathway
Mast cells (MC) are distributed in tissues throughout the human body and have long been recognized as key cells of type I hypersensitivity reactions. They also play important roles in inflammatory and immediate allergic reactions.
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
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Gene Symbol | Full Name |
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ACTN2 | actinin, alpha 2 |
AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
ANGPT1 | angiopoietin 1 |
ARAF | A-Raf proto-oncogene, serine/threonine kinase |
ARRB1 | arrestin, beta 1 |
ARRB2 | arrestin, beta 2 |
BAD | BCL2-associated agonist of cell death |
BRAF | B-Raf proto-oncogene, serine/threonine kinase |
BTC | betacellulin |
BTK | Bruton agammaglobulinemia tyrosine kinase |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
CAMK2D | calcium/calmodulin-dependent protein kinase II delta |
CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
CASP9 | caspase 9, apoptosis-related cysteine peptidase |
CD19 | CD19 molecule |
CD28 | CD28 molecule |
CD80 | CD80 molecule |
CD86 | CD86 molecule |
CDC34 | cell division cycle 34 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CHUK | conserved helix-loop-helix ubiquitous kinase |
CREB1 | cAMP responsive element binding protein 1 |
CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
CSK | c-src tyrosine kinase |
DLG4 | discs, large homolog 4 (Drosophila) |
HBEGF | heparin-binding EGF-like growth factor |
DUSP1 | dual specificity phosphatase 1 |
DUSP2 | dual specificity phosphatase 2 |
DUSP4 | dual specificity phosphatase 4 |
DUSP5 | dual specificity phosphatase 5 |
DUSP6 | dual specificity phosphatase 6 |
DUSP7 | dual specificity phosphatase 7 |
DUSP8 | dual specificity phosphatase 8 |
DUSP9 | dual specificity phosphatase 9 |
EGF | epidermal growth factor |
EGFR | epidermal growth factor receptor |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
ERBB4 | erb-b2 receptor tyrosine kinase 4 |
EREG | epiregulin |
FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 |
FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
FGA | fibrinogen alpha chain |
FGB | fibrinogen beta chain |
FGF1 | fibroblast growth factor 1 (acidic) |
FGF2 | fibroblast growth factor 2 (basic) |
FGF3 | fibroblast growth factor 3 |
FGF4 | fibroblast growth factor 4 |
FGF5 | fibroblast growth factor 5 |
FGF6 | fibroblast growth factor 6 |
FGF7 | fibroblast growth factor 7 |
FGF8 | fibroblast growth factor 8 (androgen-induced) |
FGF9 | fibroblast growth factor 9 |
FGF10 | fibroblast growth factor 10 |
FGFR1 | fibroblast growth factor receptor 1 |
FGFR3 | fibroblast growth factor receptor 3 |
FGFR2 | fibroblast growth factor receptor 2 |
FGFR4 | fibroblast growth factor receptor 4 |
FGG | fibrinogen gamma chain |
FOXO1 | forkhead box O1 |
FOXO3 | forkhead box O3 |
FN1 | fibronectin 1 |
FOS | FBJ murine osteosarcoma viral oncogene homolog |
MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GAB1 | GRB2-associated binding protein 1 |
GRB2 | growth factor receptor-bound protein 2 |
GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
GSK3A | glycogen synthase kinase 3 alpha |
GSK3B | glycogen synthase kinase 3 beta |
NRG1 | neuregulin 1 |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
HRAS | Harvey rat sarcoma viral oncogene homolog |
IGHE | immunoglobulin heavy constant epsilon |
IGKC | immunoglobulin kappa constant |
IGLC1 | immunoglobulin lambda constant 1 (Mcg marker) |
IGLC2 | immunoglobulin lambda constant 2 (Kern-Oz- marker) |
IGLC3 | immunoglobulin lambda constant 3 (Kern-Oz+ marker) |
IGLC6 | immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene) |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
IL2 | interleukin 2 |
IL2RA | interleukin 2 receptor, alpha |
IL2RB | interleukin 2 receptor, beta |
IL2RG | interleukin 2 receptor, gamma |
IL3 | interleukin 3 |
IL3RA | interleukin 3 receptor, alpha (low affinity) |
IL5 | interleukin 5 |