Gene Symbol | Pgp |
Entrez Gene ID | 67078 |
Full Name | phosphoglycolate phosphatase |
Synonyms | 1700012G19Rik,AI481330,AUM,G3PP |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Pgp cDNA ORF clone
Gene Symbol | Pgp |
Entrez Gene ID | 67078 |
Full Name | phosphoglycolate phosphatase |
Synonyms | 1700012G19Rik,AI481330,AUM,G3PP |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_025954.4 | NP_080230.2 | glycerol-3-phosphate phosphatase |
NM_025954.3 | NP_080230.2 | glycerol-3-phosphate phosphatase |
Pan troglodytes (chimpanzee) | PGP | XP_001162359.2 |
LOC695591 | XP_001084229.2 | |
Canis lupus familiaris (dog) | PGP | XP_005622146.1 |
Rattus norvegicus (Norway rat) | Pgp | NP_001162623.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011350 | XP_309300.4 |
Caenorhabditis elegans (roundworm) | C53A3.2 | NP_504511.1 |
Caenorhabditis elegans (roundworm) | CELE_K09H11.7 | NP_504509.1 |
Caenorhabditis elegans (roundworm) | C45E5.1 | NP_500857.2 |
Saccharomyces cerevisiae (baker's yeast) | PHO13 | NP_010045.1 |
Kluyveromyces lactis | KLLA0D19382g | XP_453922.1 |
Schizosaccharomyces pombe (fission yeast) | pho2 | NP_596255.1 |
Neurospora crassa | NCU00088 | XP_957212.1 |
Bos taurus (cattle) | PGP | NP_001033261.1 |
Caenorhabditis elegans (roundworm) | F44E7.2 | NP_504512.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_10149 | XP_003713787.1 |
Arabidopsis thaliana (thale cress) | PGLP2 | NP_199587.1 |
Gallus gallus (chicken) | PGP | NP_001025809.1 |
Caenorhabditis elegans (roundworm) | K02D10.1 | NP_001122707.1 |
Oryza sativa (rice) | Os09g0261300 | NP_001062708.2 |
Xenopus tropicalis (tropical clawed frog) | pgp | XP_002932481.1 |
Homo sapiens (human) | PGP | NP_001035830.1 |
Mus musculus (house mouse) | Pgp | NP_080230.2 |
Danio rerio (zebrafish) | pgp | NP_997891.2 |
Drosophila melanogaster (fruit fly) | CG5567 | NP_649015.2 |
Eremothecium gossypii | AGOS_ABL184W | NP_982763.1 |
An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation.
Segerer G, Hadamek K, Zundler M, Fekete A, Seifried A, Mueller MJ, Koentgen F, Gessler M, Jeanclos E, Gohla A
Scientific reports635160(2016 Oct)
Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM.
Seifried A, Bergeron A, Boivin B, Gohla A
Free radical biology & medicine9775-84(2016 08)
Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic ?-cells and hepatocytes.
Mugabo Y, Zhao S, Seifried A, Gezzar S, Al-Mass A, Zhang D, Lamontagne J, Attane C, Poursharifi P, Iglesias J, Joly E, Peyot ML, Gohla A, Madiraju SR, Prentki M
Proceedings of the National Academy of Sciences of the United States of America113(4)E430-9(2016 Jan)
Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities.
Seifried A, Knobloch G, Duraphe PS, Segerer G, Manhard J, Schindelin H, Schultz J, Gohla A
The Journal of biological chemistry289(6)3416-31(2014 Feb)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
our findings establish that PGP, an aspartate-dependent HAD phosphatase, is transiently inactivated by reversible oxidation in cells
Title: Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM.
A previously known phosphoglycolate phosphatase (PGP) with an uncertain function acts as a specific glycerol-3-phosphate phosphatase and plays a role in the glucose and lipid metabolism and signaling, and the response to metabolic stress.
Title: Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic ?-cells and hepatocytes.
Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities.
Title: Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities.
The following Pgp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pgp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu17793 | |
Clone ID Related Accession (Same CDS sequence) | NM_025954.4 , NM_025954.3 | |
Accession Version | NM_025954.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-01 | |
Organism | Mus musculus(house mouse) | |
Product | glycerol-3-phosphate phosphatase | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC154237.1. On Feb 9, 2019 this sequence version replaced NM_025954.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.4017591.1, SRR7345562.3948949.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGAGG CGGAAGCCGG TGGCGACGAA GCCCGCTGCG TGCGGCTGAG CGCCGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_080230.2 |
CDS | 85..1050 |
Translation |
Target ORF information:
Target ORF information:
|
NM_025954.4 |
1 | ATGGCAGAGG CGGAAGCCGG TGGCGACGAA GCCCGCTGCG TGCGGCTGAG CGCCGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17793 | |
Clone ID Related Accession (Same CDS sequence) | NM_025954.4 , NM_025954.3 | |
Accession Version | NM_025954.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-09-22 | |
Organism | Mus musculus(house mouse) | |
Product | glycerol-3-phosphate phosphatase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC154237.1. On Nov 17, 2006 this sequence version replaced NM_025954.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC040100.1, SRR1660817.40808.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCAGAGG CGGAAGCCGG TGGCGACGAA GCCCGCTGCG TGCGGCTGAG CGCCGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_080230.2 |
CDS | 38..1003 |
Translation |
Target ORF information:
Target ORF information:
|
NM_025954.3 |
1 | ATGGCAGAGG CGGAAGCCGG TGGCGACGAA GCCCGCTGCG TGCGGCTGAG CGCCGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation. |
Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM. |
Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic ?-cells and hepatocytes. |
Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |