Gene Symbol | Mpc2 |
Entrez Gene ID | 100359982 |
Full Name | mitochondrial pyruvate carrier 2 |
Synonyms | Brp44,RGD1563422,SLC54A2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Mpc2 cDNA ORF clone
gRNAs
Gene Symbol | Mpc2 |
Entrez Gene ID | 100359982 |
Full Name | mitochondrial pyruvate carrier 2 |
Synonyms | Brp44,RGD1563422,SLC54A2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006250126.2 | XP_006250188.1 | mitochondrial pyruvate carrier 2 isoform X1 |
NM_001077643.2 | NP_001071111.1 | mitochondrial pyruvate carrier 2 isoform 1 |
NM_001322942.1 | NP_001309871.1 | mitochondrial pyruvate carrier 2 isoform 2 |
Mus musculus (house mouse) | Mpc2 | NP_081706.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_02668 | XP_003721106.1 |
Homo sapiens (human) | MPC2 | NP_001137146.1 |
BRP44 | XP_001091697.1 | |
Drosophila melanogaster (fruit fly) | CG9396 | NP_649912.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC24B11.09 | NP_592846.1 |
Neurospora crassa | NCU03155 | XP_964561.1 |
Oryza sativa (rice) | Os08g0344300 | NP_001061597.1 |
Xenopus tropicalis (tropical clawed frog) | mpc2 | NP_001016695.1 |
Bos taurus (cattle) | BRP44 | NP_001180050.1 |
Gallus gallus (chicken) | BRP44 | NP_001265053.1 |
Danio rerio (zebrafish) | mpc2 | NP_997757.1 |
Drosophila melanogaster (fruit fly) | CG9399 | NP_001163571.1 |
Arabidopsis thaliana (thale cress) | AT4G22310 | NP_193962.1 |
Pan troglodytes (chimpanzee) | BRP44 | XP_001174837.1 |
Oryza sativa (rice) | Os07g0449100 | NP_001059546.1 |
Canis lupus familiaris (dog) | MPC2 | XP_537209.1 |
Rattus norvegicus (Norway rat) | Mpc2 | NP_001071111.1 |
Kluyveromyces lactis | KLLA0A05500g | XP_451243.1 |
Eremothecium gossypii | AGOS_AEL210C | NP_984651.1 |
Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion.
Vigueira PA, McCommis KS, Schweitzer GG, Remedi MS, Chambers KT, Fu X, McDonald WG, Cole SL, Colca JR, Kletzien RF, Burgess SC, Finck BN
Cell reports7(6)2042-2053(2014 Jun)
Identification and functional expression of the mitochondrial pyruvate carrier.
Herzig S, Raemy E, Montessuit S, Veuthey JL, Zamboni N, Westermann B, Kunji ER, Martinou JC
Science (New York, N.Y.)337(6090)93-6(2012 Jul)
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.
Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J
Science (New York, N.Y.)337(6090)96-100(2012 Jul)
Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Mpc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mpc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa35537 | |
Clone ID Related Accession (Same CDS sequence) | NM_001322942.1 | |
Accession Version | NM_001322942.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-24 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | mitochondrial pyruvate carrier 2 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07021646.1. On Apr 15, 2016 this sequence version replaced XM_006250127.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BE112736.1, FQ216993.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGCAGCTG CCGGCGCCCG AGGCCTGCGG GCCACCTACC ACCGACTCAT GGATAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001309871.1 |
CDS | 247..573 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCTG CCGGCGCCCG AGGCCTGCGG GCCACCTACC ACCGACTCAT GGATAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa35536 | |
Clone ID Related Accession (Same CDS sequence) | XM_006250126.2 | |
Accession Version | XM_006250126.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 351bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | mitochondrial pyruvate carrier 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006250126.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTG CCGGCGCCCG AGGCCTGCGG GCCACCTACC ACCGACTCAT GGATAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006250188.1 |
CDS | 796..1146 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCTG CCGGCGCCCG AGGCCTGCGG GCCACCTACC ACCGACTCAT GGATAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa63214 | |
Clone ID Related Accession (Same CDS sequence) | NM_001077643.2 | |
Accession Version | NM_001077643.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | mitochondrial pyruvate carrier 2 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07021646.1 and FM061478.1. On Apr 15, 2016 this sequence version replaced NM_001077643.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BQ192616.1, CF110543.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGCAGCTG CCGGCGCCCG AGGCCTGCGG GCCACCTACC ACCGACTCAT GGATAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001071111.1 |
CDS | 247..630 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCTG CCGGCGCCCG AGGCCTGCGG GCCACCTACC ACCGACTCAT GGATAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. |
Identification and functional expression of the mitochondrial pyruvate carrier. |
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. |
Proteomic characterization of the human sperm nucleus. |
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. |