Eif4h cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Eif4h
Entrez Gene ID	288599
Full Name	eukaryotic translation initiation factor 4H
Synonyms	Wbscr1
General protein information	Preferred Names eukaryotic translation initiation factor 4H Names eukaryotic translation initiation factor 4H Williams-Beuren syndrome chromosome region 1 homolog eIF-4H williams-Beuren syndrome chromosomal region 1 protein homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q12

mRNA and Protein(s)

mRNA Protein Name

NM_001006957.2 NP_001006958.1 eukaryotic translation initiation factor 4H

XM_006249134.2 XP_006249196.2 eukaryotic translation initiation factor 4H isoform X1
Pathways from BioSystems

mRNA	Protein	Name
NM_001006957.2	NP_001006958.1	eukaryotic translation initiation factor 4H
XM_006249134.2	XP_006249196.2	eukaryotic translation initiation factor 4H isoform X1

Homologies

	EIF4H	XP_001082007.1
Canis lupus familiaris (dog)	EIF4H	XP_005621070.1
Bos taurus (cattle)	EIF4H	NP_001069220.1
Rattus norvegicus (Norway rat)	Eif4h	NP_001006958.1
Pan troglodytes (chimpanzee)	EIF4H	XP_003951096.1
Mus musculus (house mouse)	Eif4h	NP_291039.1
Gallus gallus (chicken)	LOC100859865	XP_003642445.1
Danio rerio (zebrafish)	eif4h	NP_991258.2
Xenopus tropicalis (tropical clawed frog)	eif4h	NP_001096677.1
Homo sapiens (human)	EIF4H	NP_071496.1

Gene Ontology
Bibliography

Related articles in PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Growth defects and impaired cognitive-behavioral abilities in mice with knockout for Eif4h, a gene located in the mouse homolog of the Williams-Beuren syndrome critical region.
Capossela S, Muzio L, Bertolo A, Bianchi V, Dati G, Chaabane L, Godi C, Politi LS, Biffo S, D'Adamo P, Mallamaci A, Pannese M
The American journal of pathology180(3)1121-35(2012 Mar)

mRNA helicases: the tacticians of translational control.
Parsyan A, Svitkin Y, Shahbazian D, Gkogkas C, Lasko P, Merrick WC, Sonenberg N
Nature reviews. Molecular cell biology12(4)235-45(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif4h gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif4h cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10890	NM_001006957.2 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 4H (Eif4h), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa57796	XM_006249134.2 Latest version!	Rattus norvegicus eukaryotic translation initiation factor 4H (Eif4h), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif4h ( NM_001006957.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001006958.1 Rattus norvegicus eukaryotic translation initiation factor 4H (Eif4h), mRNA.

Price & Availability↑

CloneID	ORa10890
Clone ID Related Accession (Same CDS sequence)	NM_001006957.2
Accession Version	NM_001006957.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 4H
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB718613.1 and BC083818.1. On Aug 4, 2012 this sequence version replaced NM_001006957.1. ##Evidence-Data-START## Transcript exon combination :: BC083818.1, FQ099171.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACT TCGATACCTA CGACGATCGG GCCTACAGCA GCTTCGGCGG CGGTAGAGGG 
TCCCGCGGCA GTGCTGGTGG CCATGGGTCC CGAAGCCAGA AGGAGCTACC CACAGAGCCC 
CCCTACACAG CTTACGTAGG AAATCTCCCT TTTAACACAG TTCAGGGTGA CATAGATGCT 
ATCTTTAAGG ATCTCAGCAT ACGGAGTGTG CGGCTAGTCA GAGACAAAGA CACAGACAAA 
TTTAAAGGGT TCTGCTATGT AGAATTTGAT GAGGTGGATT CCCTGAAGGA GGCTCTGACC 
TACGACGGTG CACTCTTGGG TGACCGGTCA CTTCGTGTGG ACATTGCAGA AGGCAGAAAA 
CAAGACAAAG GTGGCTTTGG GTTCAGGAAA GGCGGACCTG ATGACAGAGG AATGGGTGGC 
TCTCGAGAAC CGAGAGGTGG ATGGGATTCC CGGGATGACT TCAGCTCTGG CTACAGGGAT 
GACTTCTTAG GGGGTAGGGG GGGCAGTCGC CCTGGGGACC GGCGAGCAGG CCCTCCAATG 
GGGAGTCGCT TTCGAGATGG CCCTCCTCTG CGTGGCTCCA ACATGGACTT CAGAGAACCC 
ACAGAAGAGG AACGAGCACA GAGACCGCGG CTGCAGCTTA AACCTCGGAC AGTGGCAACA 
CCCCTCAATC AAGTAGCCAA CCCCAACTCA GCCATCTTCG GGGGAGCCAG GCCCAGAGAG 
GAAGTGGTTC AGAAGGAGCA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006958.1
CDS	39..785
Translation	MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGGSREPRGGWDSRDDFSSGYRDDFLGGRGGSRPGDRRAGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE

Target ORF information:

RefSeq Version	NM_001006957.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 4H (Eif4h), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001006957.2

ORF Insert Sequence:

ATGGCGGACT TCGATACCTA CGACGATCGG GCCTACAGCA GCTTCGGCGG CGGTAGAGGG 
TCCCGCGGCA GTGCTGGTGG CCATGGGTCC CGAAGCCAGA AGGAGCTACC CACAGAGCCC 
CCCTACACAG CTTACGTAGG AAATCTCCCT TTTAACACAG TTCAGGGTGA CATAGATGCT 
ATCTTTAAGG ATCTCAGCAT ACGGAGTGTG CGGCTAGTCA GAGACAAAGA CACAGACAAA 
TTTAAAGGGT TCTGCTATGT AGAATTTGAT GAGGTGGATT CCCTGAAGGA GGCTCTGACC 
TACGACGGTG CACTCTTGGG TGACCGGTCA CTTCGTGTGG ACATTGCAGA AGGCAGAAAA 
CAAGACAAAG GTGGCTTTGG GTTCAGGAAA GGCGGACCTG ATGACAGAGG AATGGGTGGC 
TCTCGAGAAC CGAGAGGTGG ATGGGATTCC CGGGATGACT TCAGCTCTGG CTACAGGGAT 
GACTTCTTAG GGGGTAGGGG GGGCAGTCGC CCTGGGGACC GGCGAGCAGG CCCTCCAATG 
GGGAGTCGCT TTCGAGATGG CCCTCCTCTG CGTGGCTCCA ACATGGACTT CAGAGAACCC 
ACAGAAGAGG AACGAGCACA GAGACCGCGG CTGCAGCTTA AACCTCGGAC AGTGGCAACA 
CCCCTCAATC AAGTAGCCAA CCCCAACTCA GCCATCTTCG GGGGAGCCAG GCCCAGAGAG 
GAAGTGGTTC AGAAGGAGCA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Eif4h ( XM_006249134.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249196.2 Rattus norvegicus eukaryotic translation initiation factor 4H (Eif4h), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa57796
Clone ID Related Accession (Same CDS sequence)	XM_006249134.2
Accession Version	XM_006249134.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	eukaryotic translation initiation factor 4H isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249134.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGACT TCGATACCTA CGACGATCGG GCCTACAGCA GCTTCGGCGG CGGTAGAGGG 
TCCCGCGGCA GTGCTGGTGG CCATGGGTCC CGAAGCCAGA AGGAGCTACC CACAGAGCCC 
CCCTACACAG CTTACGTAGG AAATCTCCCT TTTAACACAG TTCAGGGTGA CATAGATGCT 
ATCTTTAAGG ATCTCAGCAT ACGGAGTGTG CGGCTAGTCA GAGACAAAGA CACAGACAAA 
TTTAAAGGGT TCTGCTATGT AGAATTTGAT GAGGTGGATT CCCTGAAGGA GGCTCTGACC 
TACGACGGTG CACTCTTGGG TGACCGGTCA CTTCGTGTGG ACATTGCAGA AGGCAGAAAA 
CAAGACAAAG GTGGCTTTGG GTTCAGGAAA GGCGGACCTG ATGACAGAGG CTACAGGGAT 
GACTTCTTAG GGGGTAGGGG GGGCAGTCGC CCTGGGGACC GGCGAGCAGG CCCTCCAATG 
GGGAGTCGCT TTCGAGATGG CCCTCCTCTG CGTGGCTCCA ACATGGACTT CAGAGAACCC 
ACAGAAGAGG AACGAGCACA GAGACCGCGG CTGCAGCTTA AACCTCGGAC AGTGGCAACA 
CCCCTCAATC AAGTAGCCAA CCCCAACTCA GCCATCTTCG GGGGAGCCAG GCCCAGAGAG 
GAAGTGGTTC AGAAGGAGCA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249196.2
CDS	69..755
Translation	MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGYRDDFLGGRGGSRPGDRRAGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE

Target ORF information:

RefSeq Version	XM_006249134.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus eukaryotic translation initiation factor 4H (Eif4h), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249134.2

ORF Insert Sequence:

ATGGCGGACT TCGATACCTA CGACGATCGG GCCTACAGCA GCTTCGGCGG CGGTAGAGGG 
TCCCGCGGCA GTGCTGGTGG CCATGGGTCC CGAAGCCAGA AGGAGCTACC CACAGAGCCC 
CCCTACACAG CTTACGTAGG AAATCTCCCT TTTAACACAG TTCAGGGTGA CATAGATGCT 
ATCTTTAAGG ATCTCAGCAT ACGGAGTGTG CGGCTAGTCA GAGACAAAGA CACAGACAAA 
TTTAAAGGGT TCTGCTATGT AGAATTTGAT GAGGTGGATT CCCTGAAGGA GGCTCTGACC 
TACGACGGTG CACTCTTGGG TGACCGGTCA CTTCGTGTGG ACATTGCAGA AGGCAGAAAA 
CAAGACAAAG GTGGCTTTGG GTTCAGGAAA GGCGGACCTG ATGACAGAGG CTACAGGGAT 
GACTTCTTAG GGGGTAGGGG GGGCAGTCGC CCTGGGGACC GGCGAGCAGG CCCTCCAATG 
GGGAGTCGCT TTCGAGATGG CCCTCCTCTG CGTGGCTCCA ACATGGACTT CAGAGAACCC 
ACAGAAGAGG AACGAGCACA GAGACCGCGG CTGCAGCTTA AACCTCGGAC AGTGGCAACA 
CCCCTCAATC AAGTAGCCAA CCCCAACTCA GCCATCTTCG GGGGAGCCAG GCCCAGAGAG 
GAAGTGGTTC AGAAGGAGCA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Growth defects and impaired cognitive-behavioral abilities in mice with knockout for Eif4h, a gene located in the mouse homolog of the Williams-Beuren syndrome critical region.
The American journal of pathology180(3)1121-35(2012 Mar)
Capossela S,Muzio L,Bertolo A,Bianchi V,Dati G,Chaabane L,Godi C,Politi LS,Biffo S,D'Adamo P,Mallamaci A,Pannese M

mRNA helicases: the tacticians of translational control.
Nature reviews. Molecular cell biology12(4)235-45(2011 Apr)
Parsyan A,Svitkin Y,Shahbazian D,Gkogkas C,Lasko P,Merrick WC,Sonenberg N

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Eif4h cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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