Gene Symbol | Manba |
Entrez Gene ID | 310864 |
Full Name | mannosidase beta |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Manba cDNA ORF clone
gRNAs
Gene Symbol | Manba |
Entrez Gene ID | 310864 |
Full Name | mannosidase beta |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001031655.1 | NP_001026825.1 | beta-mannosidase precursor |
Danio rerio (zebrafish) | manba | NP_956453.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01178 | XP_003714062.1 |
Neurospora crassa | NCU00890 | XP_964806.1 |
Pan troglodytes (chimpanzee) | MANBA | XP_001169005.1 |
MANBA | XP_001101549.2 | |
Drosophila melanogaster (fruit fly) | CG12582 | NP_649436.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000143 | XP_311001.5 |
Xenopus tropicalis (tropical clawed frog) | manba | XP_002934804.2 |
Homo sapiens (human) | MANBA | NP_005899.3 |
Bos taurus (cattle) | MANBA | NP_776812.1 |
Gallus gallus (chicken) | MANBA | XP_420666.3 |
Danio rerio (zebrafish) | LOC100331766 | XP_002664183.1 |
Caenorhabditis elegans (roundworm) | C33G3.4 | NP_510342.1 |
Canis lupus familiaris (dog) | MANBA | XP_005639293.1 |
Mus musculus (house mouse) | Manba | NP_081564.3 |
Rattus norvegicus (Norway rat) | Manba | NP_001026825.1 |
Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity.
Boonen M, Vogel P, Platt KA, Dahms N, Kornfeld S
Molecular biology of the cell20(20)4381-9(2009 Oct)
Beta-mannosidosis mice: a model for the human lysosomal storage disease.
Zhu M, Lovell KL, Patterson JS, Saunders TL, Hughes ED, Friderici KH
Human molecular genetics15(3)493-500(2006 Feb)
Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis.
Sleat DE, Sohar I, Lackland H, Majercak J, Lobel P
The Journal of biological chemistry271(32)19191-8(1996 Aug)
A gene (Bmn) controlling beta-mannosidase activity in the mouse is located in the distal part of chromosome 3.
Lundin LG
Biochemical genetics25(7-8)603-10(1987 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Manba gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Manba cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa42820 | |
Clone ID Related Accession (Same CDS sequence) | NM_001031655.1 | |
Accession Version | NM_001031655.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2646bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | beta-mannosidase precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099094.1. On Aug 12, 2005 this sequence version replaced XM_227701.3. ##Evidence-Data-START## Transcript exon combination :: BC099094.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCATCTCC ACCTGCTCTT TCTGTTGGCG CTGTGCGGGG CAGGCTGTAT GGCCGCAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001026825.1 |
CDS | 16..2661 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCATCTCC ACCTGCTCTT TCTGTTGGCG CTGTGCGGGG CAGGCTGTAT GGCCGCAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity. |
Beta-mannosidosis mice: a model for the human lysosomal storage disease. |
Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis. |
A gene (Bmn) controlling beta-mannosidase activity in the mouse is located in the distal part of chromosome 3. |