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Spo11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Spo11
Entrez Gene ID 366261
Full Name SPO11, initiator of meiotic double stranded breaks
General protein information
Preferred Names

SPO11, initiator of meiotic double stranded breaks

Names

meiotic recombination protein SPO11
SPO11 meiotic protein covalently bound to DSB homolog
sporulation protein, meiosis-specific, SPO11 homolog
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

3

3q42

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006235698.3 XP_006235760.1 meiotic recombination protein SPO11 isoform X1
XM_006235701.2 XP_006235763.1 meiotic recombination protein SPO11 isoform X2
XM_008762527.2 XP_008760749.1 meiotic recombination protein SPO11 isoform X3
XM_008762525.2 XP_008760747.1 meiotic recombination protein SPO11 isoform X3
NM_001108964.1 NP_001102434.1 meiotic recombination protein SPO11

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) SPO11 XP_514741.2
Bos taurus (cattle) SPO11 NP_001180019.1
Rattus norvegicus (Norway rat) Spo11 NP_001102434.1
Gallus gallus (chicken) SPO11 XP_001232076.2
Drosophila melanogaster (fruit fly) mei-W68 NP_995901.1
Arabidopsis thaliana (thale cress) RHL2 NP_195902.1
Oryza sativa (rice) Os03g0284800 NP_001049765.2
Canis lupus familiaris (dog) SPO11 XP_853487.1
Mus musculus (house mouse) Spo11 NP_036176.1
Danio rerio (zebrafish) spo11 NP_991245.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP010898 XP_309793.4
Homo sapiens (human) SPO11 NP_036576.1
SPO11 XP_001088572.1

Gene Ontology


Bibliography

Related articles in PubMed

Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein.
Finsterbusch F, Ravindranathan R, Dereli I, Stanzione M, Tr?nkner D, T?th A
PLoS genetics12(10)e1006393(2016 Oct)

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes.
Ishiguro K, Kim J, Shibuya H, Hern?ndez-Hern?ndez A, Suzuki A, Fukagawa T, Shioi G, Kiyonari H, Li XC, Schimenti J, H??g C, Watanabe Y
Genes & development28(6)594-607(2014 Mar)

HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes.
Kogo H, Tsutsumi M, Ohye T, Inagaki H, Abe T, Kurahashi H
Genes to cells : devoted to molecular & cellular mechanisms17(6)439-54(2012 Jun)

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
Kumar R, Bourbon HM, de Massy B
Genes & development24(12)1266-80(2010 Jun)

Zscan4 regulates telomere elongation and genomic stability in ES cells.
Zalzman M, Falco G, Sharova LV, Nishiyama A, Thomas M, Lee SL, Stagg CA, Hoang HG, Yang HT, Indig FE, Wersto RP, Ko MS
Nature464(7290)858-63(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Spo11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Spo11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa00404 NM_001108964.1
Latest version!		 Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
ORa26757 XM_006235698.3
Latest version!		 Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
ORa26760 XM_006235701.2
Latest version!		 Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
ORa48800 XM_008762527.2
Latest version!		 Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
ORa48800 XM_008762525.2
Latest version!		 Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone 40% OFF
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All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa00404
Clone ID Related Accession (Same CDS sequence) NM_001108964.1
Accession Version NM_001108964.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 996bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-05-27
Organism Rattus norvegicus(Norway rat)
Product meiotic recombination protein SPO11
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474062.2. On or before Oct 4, 2007 this sequence version replaced XM_345476.3, XM_001053782.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689594, SAMEA2689597 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GTCCGGGAGC ACGTGCTCAT 
TCAGTGTTGA CCTTACATTT GCACAGAGAC ATATACTACA CTGAGAGCCA GCTCTTCAGG 
AACCAGGCTG CAGTGGACAG CATTATAGAT GACATTTCCT GTATGCTGAA AGTGCCCAGG 
AGGAGTCTGC ATGTGATATC TACATCGAAG GGATTGATTG CTGGCAACTT GAGATACGTG 
GAGGAAGATG GTACCCAAGT CCAGTGCATG TGTAGTGCCA CGGCTACTGC TGTGCCATCT 
AACATTCAAG GGATGCAGAA TCTGGTCACA GATGCGAAGT TTCTGCTAAT CGTAGAGAAG 
GATGCAACAT TTCAGCGGCT CCTGGACGAC AACTTCTGCA GCAGGATGTC CCCGTGCATC 
ATGGTTACGG GAAAGGGTAC TCCAGATCTG AACACGAGGC TCTTGGTAAA GAAGCTGTGG 
GACACCTTTC ATATTCCTGT CTTCACACTG GTAGATGCTG ACCCCTACGG CATCGAGATA 
ATGTGCATCT ATAAGTACGG ATCCATGTCC ATGTCTTTTG AAGCCCACAA TCTCACTGTC 
CCAACAATCA GATGGCTTGG TCTCCTCCCT TCTGATATTA AAAGGTTAAA TATACCTAAG 
GATAGTTTGA TCCCACTGAC AAGGCGTGAC CAGATGAAGC TGGACAGTAT CCTGAGGAGG 
CCTTACATTA CCTATCACCC CTTCTGGAAA AAAGAGATGG AGATGCTGGC CGACTCTAAG 
ACGAAGGCGG AGATCCAAGC CTTGAGCTTC CTGTCGTCAG ACTATCTGTC CAGAGTGTAC 
TTGCCCAACA AGCTGAGGTT TGGAGGGTGG ATATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001102434.1
CDS114..1109
Translation

Target ORF information:

RefSeq Version NM_001108964.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001108964.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GTCCGGGAGC ACGTGCTCAT 
TCAGTGTTGA CCTTACATTT GCACAGAGAC ATATACTACA CTGAGAGCCA GCTCTTCAGG 
AACCAGGCTG CAGTGGACAG CATTATAGAT GACATTTCCT GTATGCTGAA AGTGCCCAGG 
AGGAGTCTGC ATGTGATATC TACATCGAAG GGATTGATTG CTGGCAACTT GAGATACGTG 
GAGGAAGATG GTACCCAAGT CCAGTGCATG TGTAGTGCCA CGGCTACTGC TGTGCCATCT 
AACATTCAAG GGATGCAGAA TCTGGTCACA GATGCGAAGT TTCTGCTAAT CGTAGAGAAG 
GATGCAACAT TTCAGCGGCT CCTGGACGAC AACTTCTGCA GCAGGATGTC CCCGTGCATC 
ATGGTTACGG GAAAGGGTAC TCCAGATCTG AACACGAGGC TCTTGGTAAA GAAGCTGTGG 
GACACCTTTC ATATTCCTGT CTTCACACTG GTAGATGCTG ACCCCTACGG CATCGAGATA 
ATGTGCATCT ATAAGTACGG ATCCATGTCC ATGTCTTTTG AAGCCCACAA TCTCACTGTC 
CCAACAATCA GATGGCTTGG TCTCCTCCCT TCTGATATTA AAAGGTTAAA TATACCTAAG 
GATAGTTTGA TCCCACTGAC AAGGCGTGAC CAGATGAAGC TGGACAGTAT CCTGAGGAGG 
CCTTACATTA CCTATCACCC CTTCTGGAAA AAAGAGATGG AGATGCTGGC CGACTCTAAG 
ACGAAGGCGG AGATCCAAGC CTTGAGCTTC CTGTCGTCAG ACTATCTGTC CAGAGTGTAC 
TTGCCCAACA AGCTGAGGTT TGGAGGGTGG ATATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa26757
Clone ID Related Accession (Same CDS sequence) XM_006235698.3
Accession Version XM_006235698.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1191bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product meiotic recombination protein SPO11 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235698.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGCGTTAG CGCCTATGGG GCCCGAGGCC TCGTTCTTCG ACGCCTTGGA TCGGCACAGG 
GCTTCCCTGT TGGCCATGGT GAAGAAAGGC GCAGGGGAGA CCCCTGACAG GGCCACCCGT 
GTGCCCTCTA GTTCTGAGGT TCTTACGTCT ATAGAAAATA TTATCCAAGA CATAATCAAA 
AGCTTGGCAA GAAATGAAGC GCCCGCCTTC ACAATAGACA ACAGATCGAG CTGGGAAAAC 
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGTCCATGTC TTTTGAAGCC 
CACAATCTCA CTGTCCCAAC AATCAGATGG CTTGGTCTCC TCCCTTCTGA TATTAAAAGG 
TTAAATATAC CTAAGGATAG TTTGATCCCA CTGACAAGGC GTGACCAGAT GAAGCTGGAC 
AGTATCCTGA GGAGGCCTTA CATTACCTAT CACCCCTTCT GGAAAAAAGA GATGGAGATG 
CTGGCCGACT CTAAGACGAA GGCGGAGATC CAAGCCTTGA GCTTCCTGTC GTCAGACTAT 
CTGTCCAGAG TGTACTTGCC CAACAAGCTG AGGTTTGGAG GGTGGATATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006235760.1
CDS79..1269
Translation

Target ORF information:

RefSeq Version XM_006235698.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006235698.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGCGTTAG CGCCTATGGG GCCCGAGGCC TCGTTCTTCG ACGCCTTGGA TCGGCACAGG 
GCTTCCCTGT TGGCCATGGT GAAGAAAGGC GCAGGGGAGA CCCCTGACAG GGCCACCCGT 
GTGCCCTCTA GTTCTGAGGT TCTTACGTCT ATAGAAAATA TTATCCAAGA CATAATCAAA 
AGCTTGGCAA GAAATGAAGC GCCCGCCTTC ACAATAGACA ACAGATCGAG CTGGGAAAAC 
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGTCCATGTC TTTTGAAGCC 
CACAATCTCA CTGTCCCAAC AATCAGATGG CTTGGTCTCC TCCCTTCTGA TATTAAAAGG 
TTAAATATAC CTAAGGATAG TTTGATCCCA CTGACAAGGC GTGACCAGAT GAAGCTGGAC 
AGTATCCTGA GGAGGCCTTA CATTACCTAT CACCCCTTCT GGAAAAAAGA GATGGAGATG 
CTGGCCGACT CTAAGACGAA GGCGGAGATC CAAGCCTTGA GCTTCCTGTC GTCAGACTAT 
CTGTCCAGAG TGTACTTGCC CAACAAGCTG AGGTTTGGAG GGTGGATATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa26760
Clone ID Related Accession (Same CDS sequence) XM_006235701.2
Accession Version XM_006235701.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1017bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product meiotic recombination protein SPO11 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006235701.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCGTTAG CGCCTATGGG GCCCGAGGCC TCGTTCTTCG ACGCCTTGGA TCGGCACAGG 
GCTTCCCTGT TGGCCATGGT GAAGAAAGGC GCAGGGGAGA CCCCTGACAG GGCCACCCGT 
GTGCCCTCTA GTTCTGAGGT TCTTACGTCT ATAGAAAATA TTATCCAAGA CATAATCAAA 
AGCTTGGCAA GAAATGAAGC GCCCGCCTTC ACAATAGACA ACAGATCGAG CTGGGAAAAC 
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGGTGAGTAC AGCCAAGCGA 
GTCTGCTCCT CTGCCTCCAT ACACAGTGTG CATTCGTTGG GGCGGCTGAC TTATAGCCCA 
GTAAGGCGAG GCTTTCCAGA GTGTCCTAGG GGAGCCAATC TGTGCTTCAT GGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006235763.1
CDS79..1095
Translation

Target ORF information:

RefSeq Version XM_006235701.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006235701.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCGTTAG CGCCTATGGG GCCCGAGGCC TCGTTCTTCG ACGCCTTGGA TCGGCACAGG 
GCTTCCCTGT TGGCCATGGT GAAGAAAGGC GCAGGGGAGA CCCCTGACAG GGCCACCCGT 
GTGCCCTCTA GTTCTGAGGT TCTTACGTCT ATAGAAAATA TTATCCAAGA CATAATCAAA 
AGCTTGGCAA GAAATGAAGC GCCCGCCTTC ACAATAGACA ACAGATCGAG CTGGGAAAAC 
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGGTGAGTAC AGCCAAGCGA 
GTCTGCTCCT CTGCCTCCAT ACACAGTGTG CATTCGTTGG GGCGGCTGAC TTATAGCCCA 
GTAAGGCGAG GCTTTCCAGA GTGTCCTAGG GGAGCCAATC TGTGCTTCAT GGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa48800
Clone ID Related Accession (Same CDS sequence) XM_008762527.2 , XM_008762525.2
Accession Version XM_008762527.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 951bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product meiotic recombination protein SPO11 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008762527.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGTCCATGTC TTTTGAAGCC 
CACAATCTCA CTGTCCCAAC AATCAGATGG CTTGGTCTCC TCCCTTCTGA TATTAAAAGG 
TTAAATATAC CTAAGGATAG TTTGATCCCA CTGACAAGGC GTGACCAGAT GAAGCTGGAC 
AGTATCCTGA GGAGGCCTTA CATTACCTAT CACCCCTTCT GGAAAAAAGA GATGGAGATG 
CTGGCCGACT CTAAGACGAA GGCGGAGATC CAAGCCTTGA GCTTCCTGTC GTCAGACTAT 
CTGTCCAGAG TGTACTTGCC CAACAAGCTG AGGTTTGGAG GGTGGATATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008760749.1
CDS579..1529
Translation

Target ORF information:

RefSeq Version XM_008762527.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008762527.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGTCCATGTC TTTTGAAGCC 
CACAATCTCA CTGTCCCAAC AATCAGATGG CTTGGTCTCC TCCCTTCTGA TATTAAAAGG 
TTAAATATAC CTAAGGATAG TTTGATCCCA CTGACAAGGC GTGACCAGAT GAAGCTGGAC 
AGTATCCTGA GGAGGCCTTA CATTACCTAT CACCCCTTCT GGAAAAAAGA GATGGAGATG 
CTGGCCGACT CTAAGACGAA GGCGGAGATC CAAGCCTTGA GCTTCCTGTC GTCAGACTAT 
CTGTCCAGAG TGTACTTGCC CAACAAGCTG AGGTTTGGAG GGTGGATATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa48800
Clone ID Related Accession (Same CDS sequence) XM_008762527.2 , XM_008762525.2
Accession Version XM_008762525.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 951bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product meiotic recombination protein SPO11 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008762525.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGTCCATGTC TTTTGAAGCC 
CACAATCTCA CTGTCCCAAC AATCAGATGG CTTGGTCTCC TCCCTTCTGA TATTAAAAGG 
TTAAATATAC CTAAGGATAG TTTGATCCCA CTGACAAGGC GTGACCAGAT GAAGCTGGAC 
AGTATCCTGA GGAGGCCTTA CATTACCTAT CACCCCTTCT GGAAAAAAGA GATGGAGATG 
CTGGCCGACT CTAAGACGAA GGCGGAGATC CAAGCCTTGA GCTTCCTGTC GTCAGACTAT 
CTGTCCAGAG TGTACTTGCC CAACAAGCTG AGGTTTGGAG GGTGGATATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008760747.1
CDS1004..1954
Translation

Target ORF information:

RefSeq Version XM_008762525.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus SPO11, initiator of meiotic double stranded breaks (Spo11), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008762525.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGACGTTCG AAGATGCTTT TGGCCTTCAG ATGAGACCTC AGTGTACCAC AAGAAAAATC 
AAAAGCGATT CACTAAGATC AGTTAGAAAA TTTGCTCTAA TTCTGAAAAT ATTGTCCATG 
ATTTATAAAT TAATACAGAG CAACACTTAC GCAACCAAGA GAGACATATA CTACACTGAG 
AGCCAGCTCT TCAGGAACCA GGCTGCAGTG GACAGCATTA TAGATGACAT TTCCTGTATG 
CTGAAAGTGC CCAGGAGGAG TCTGCATGTG ATATCTACAT CGAAGGGATT GATTGCTGGC 
AACTTGAGAT ACGTGGAGGA AGATGGTACC CAAGTCCAGT GCATGTGTAG TGCCACGGCT 
ACTGCTGTGC CATCTAACAT TCAAGGGATG CAGAATCTGG TCACAGATGC GAAGTTTCTG 
CTAATCGTAG AGAAGGATGC AACATTTCAG CGGCTCCTGG ACGACAACTT CTGCAGCAGG 
ATGTCCCCGT GCATCATGGT TACGGGAAAG GGTACTCCAG ATCTGAACAC GAGGCTCTTG 
GTAAAGAAGC TGTGGGACAC CTTTCATATT CCTGTCTTCA CACTGGTAGA TGCTGACCCC 
TACGGCATCG AGATAATGTG CATCTATAAG TACGGATCCA TGTCCATGTC TTTTGAAGCC 
CACAATCTCA CTGTCCCAAC AATCAGATGG CTTGGTCTCC TCCCTTCTGA TATTAAAAGG 
TTAAATATAC CTAAGGATAG TTTGATCCCA CTGACAAGGC GTGACCAGAT GAAGCTGGAC 
AGTATCCTGA GGAGGCCTTA CATTACCTAT CACCCCTTCT GGAAAAAAGA GATGGAGATG 
CTGGCCGACT CTAAGACGAA GGCGGAGATC CAAGCCTTGA GCTTCCTGTC GTCAGACTAT 
CTGTCCAGAG TGTACTTGCC CAACAAGCTG AGGTTTGGAG GGTGGATATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein.
PLoS genetics12(10)e1006393(2016 Oct)
Finsterbusch F,Ravindranathan R,Dereli I,Stanzione M,Tr?nkner D,T?th A


book

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes.
Genes & development28(6)594-607(2014 Mar)
Ishiguro K,Kim J,Shibuya H,Hern?ndez-Hern?ndez A,Suzuki A,Fukagawa T,Shioi G,Kiyonari H,Li XC,Schimenti J,H??g C,Watanabe Y


book

HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes.
Genes to cells : devoted to molecular & cellular mechanisms17(6)439-54(2012 Jun)
Kogo H,Tsutsumi M,Ohye T,Inagaki H,Abe T,Kurahashi H


book

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
Genes & development24(12)1266-80(2010 Jun)
Kumar R,Bourbon HM,de Massy B


book

Zscan4 regulates telomere elongation and genomic stability in ES cells.
Nature464(7290)858-63(2010 Apr)
Zalzman M,Falco G,Sharova LV,Nishiyama A,Thomas M,Lee SL,Stagg CA,Hoang HG,Yang HT,Indig FE,Wersto RP,Ko MS