Kcnip1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnip1
Entrez Gene ID	65023
Full Name	potassium voltage-gated channel interacting protein 1
Synonyms	Kchip1
General protein information	Preferred Names potassium voltage-gated channel interacting protein 1 Names Kv channel-interacting protein 1 A-type potassium channel modulatory protein 1 potassium channel-interacting protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q12
Summary	amino terminal is involved in the regulation of closed inactivation gating [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022929.2	NP_075218.2	Kv channel-interacting protein 1 isoform 4
NM_001261389.1	NP_001248318.1	Kv channel-interacting protein 1 isoform 3
NM_001261387.1	NP_001248316.1	Kv channel-interacting protein 1 isoform 1
NM_001261388.1	NP_001248317.1	Kv channel-interacting protein 1 isoform 2
XM_006246105.3	XP_006246167.1	Kv channel-interacting protein 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KCNIP1	XP_527113.2
Mus musculus (house mouse)	Kcnip1	NP_001177814.1
	LOC706021	XP_001094347.2
Xenopus tropicalis (tropical clawed frog)	kcnip1	XP_004912876.1
Drosophila melanogaster (fruit fly)	CG5890	NP_001163739.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002000	XP_321059.2
Homo sapiens (human)	KCNIP1	NP_001030009.1
Rattus norvegicus (Norway rat)	Kcnip1	NP_001248318.1
Gallus gallus (chicken)	KCNIP1	XP_004944838.1
Danio rerio (zebrafish)	kcnip1a	XP_001346380.2
Canis lupus familiaris (dog)	KCNIP1	XP_005619276.1
Bos taurus (cattle)	KCNIP1	NP_001013622.1

Gene Ontology
Bibliography

Related articles in PubMed

Neuroprotective or neurotoxic effects of 4-aminopyridine mediated by KChIP1 regulation through adjustment of Kv 4.3 potassium channels expression and GABA-mediated transmission in primary hippocampal cells.
Del Pino J, Frejo MT, Baselga MJ, Capo MA, Moyano P, Garc?a JM, D?az MJ
Toxicology333107-17(2015 Jul)

Distribution and functional expression of Kv4 family ? subunits and associated KChIP ? subunits in the bed nucleus of the stria terminalis.
Rainnie DG, Hazra R, Dabrowska J, Guo JD, Li CC, Dewitt S, Muly EC
The Journal of comparative neurology522(3)609-25(2014 Feb)

Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.
Dabrowska J, Rainnie DG
Neuroscience171(3)721-33(2010 Dec)

The diversity of calcium sensor proteins in the regulation of neuronal function.
McCue HV, Haynes LP, Burgoyne RD
Cold Spring Harbor perspectives in biology2(8)a004085(2010 Aug)

Gene expression profiling in brain regions of a rat model displaying schizophrenia-related features.
Van Schijndel JE, Van Zweeden M, Van Loo KM, Martens GJ
Behavioural brain research207(2)476-9(2010 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

KChIP1 plays a neuroprotective role against 4-AP acute induced cell death in primary hippocampal cells through regulation of Kv 4.3 and GABA transmission but this is lost after long term exposure.
Title: Neuroprotective or neurotoxic effects of 4-aminopyridine mediated by KChIP1 regulation through adjustment of Kv 4.3 potassium channels expression and GABA-mediated transmission in primary hippocampal cells.

This study demonistrared that the expression and function of KCHIP1 channels in neurons of the rat bed nucleus of the stria terminalis.
Title: Distribution and functional expression of Kv4 family ? subunits and associated KChIP ? subunits in the bed nucleus of the stria terminalis.

KChIP1 is selectively expressed in BLA interneurons where it may function to regulate the activity of A-type potassium channels. Hence, KChIP1 might be considered as a specific regulator of GABAergic inhibitory circuits in the basolateral amygdala.
Title: Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.

Aph1b and KCnIP1 are significantly differentially expressed in a number of brain tissues of a schizophrenia model; KCnIP1 is an attractive novel candidate gene that may play a role in the complex phenotype
Title: Gene expression profiling in brain regions of a rat model displaying schizophrenia-related features.

PUFAs inhibit Kv4/KChIP channels by facilitating inactivation from open and closed gating states and access of the fatty acid to the internal leaflet of the membrane is important
Title: Inhibitory effects of polyunsaturated fatty acids on Kv4/KChIP potassium channels.

The following Kcnip1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnip1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06439	NM_022929.2 Latest version!	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa09189	NM_001261387.1 Latest version!	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa09193	NM_001261388.1 Latest version!	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa09196	NM_001261389.1 Latest version!	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa32951	XM_006246105.3 Latest version!	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnip1 ( NM_022929.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_075218.2 Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	ORa06439
Clone ID Related Accession (Same CDS sequence)	NM_022929.2
Accession Version	NM_022929.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	Kv channel-interacting protein 1 isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029265.1 and AABR07029260.1. On May 10, 2012 this sequence version replaced NM_022929.1. Transcript Variant: This variant (4) uses an alternate 5' exon and lacks an exon in the 5' coding region compared to variant 1. The resulting protein (isoform 4) has a distinct N-terminus and is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY082658.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGGCCG TCATGGGTAC CTTCTCGTCC CTGCAGACCA AACAAAGGCG ACCCTCTAAA 
GACAAGATCG AGGATGATCT GGAGATGACC ATGGTTTGCC ATCGGCCTGA GGGACTGGAG 
CAGCTTGAGG CACAGACGAA CTTCACCAAG AGAGAACTGC AAGTCCTTTA CCGGGGATTC 
AAAAACGAGT GCCCCAGTGG TGTGGTTAAC GAAGAGACAT TCAAGCAGAT CTACGCTCAG 
TTTTTCCCTC ATGGAGATGC CAGCACATAC GCACATTACC TCTTCAATGC CTTCGACACC 
ACCCAGACAG GCTCTGTAAA GTTCGAGGAC TTTGTGACTG CTCTGTCGAT TTTACTGAGA 
GGAACGGTCC ATGAAAAACT GAGGTGGACG TTTAATTTGT ACGACATCAA TAAAGACGGC 
TACATAAACA AAGAGGAGAT GATGGACATA GTGAAAGCCA TCTATGACAT GATGGGGAAA 
TACACCTATC CTGTGCTCAA AGAGGACACT CCCAGGCAGC ACGTGGACGT CTTCTTCCAG 
AAAATGGATA AAAATAAAGA TGGCATTGTA ACGTTAGACG AATTTCTCGA GTCCTGTCAG 
GAGGATGACA ACATCATGAG GTCTCTACAG CTGTTCCAAA ATGTCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075218.2
CDS	1..651
Translation	MGAVMGTFSSLQTKQRRPSKDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM

Target ORF information:

RefSeq Version	NM_022929.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022929.2

ORF Insert Sequence:

ATGGGGGCCG TCATGGGTAC CTTCTCGTCC CTGCAGACCA AACAAAGGCG ACCCTCTAAA 
GACAAGATCG AGGATGATCT GGAGATGACC ATGGTTTGCC ATCGGCCTGA GGGACTGGAG 
CAGCTTGAGG CACAGACGAA CTTCACCAAG AGAGAACTGC AAGTCCTTTA CCGGGGATTC 
AAAAACGAGT GCCCCAGTGG TGTGGTTAAC GAAGAGACAT TCAAGCAGAT CTACGCTCAG 
TTTTTCCCTC ATGGAGATGC CAGCACATAC GCACATTACC TCTTCAATGC CTTCGACACC 
ACCCAGACAG GCTCTGTAAA GTTCGAGGAC TTTGTGACTG CTCTGTCGAT TTTACTGAGA 
GGAACGGTCC ATGAAAAACT GAGGTGGACG TTTAATTTGT ACGACATCAA TAAAGACGGC 
TACATAAACA AAGAGGAGAT GATGGACATA GTGAAAGCCA TCTATGACAT GATGGGGAAA 
TACACCTATC CTGTGCTCAA AGAGGACACT CCCAGGCAGC ACGTGGACGT CTTCTTCCAG 
AAAATGGATA AAAATAAAGA TGGCATTGTA ACGTTAGACG AATTTCTCGA GTCCTGTCAG 
GAGGATGACA ACATCATGAG GTCTCTACAG CTGTTCCAAA ATGTCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnip1 ( NM_001261387.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001248316.1 Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa09189
Clone ID Related Accession (Same CDS sequence)	NM_001261387.1
Accession Version	NM_001261387.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	Kv channel-interacting protein 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029266.1 and AABR07029260.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN02642596, SAMN02642606 [ECO:0000350] ##Evidence-Data-END##

ATGAGCGGCT GCTCCAAAAG ATGCAGACTC GGGTTCGTGA AATTTGCCCA GACCATCTTT 
AAACTCATCA CCGGGACCCT CAGCAAAGAC ATCGCCTGGT GGTATTACCA GTATCAGAGA 
GACAAGATCG AGGATGATCT GGAGATGACC ATGGTTTGCC ATCGGCCTGA GGGACTGGAG 
CAGCTTGAGG CACAGACGAA CTTCACCAAG AGAGAACTGC AAGTCCTTTA CCGGGGATTC 
AAAAACGAGT GCCCCAGTGG TGTGGTTAAC GAAGAGACAT TCAAGCAGAT CTACGCTCAG 
TTTTTCCCTC ATGGAGATGC CAGCACATAC GCACATTACC TCTTCAATGC CTTCGACACC 
ACCCAGACAG GCTCTGTAAA GTTCGAGGAC TTTGTGACTG CTCTGTCGAT TTTACTGAGA 
GGAACGGTCC ATGAAAAACT GAGGTGGACG TTTAATTTGT ACGACATCAA TAAAGACGGC 
TACATAAACA AAGAGGAGAT GATGGACATA GTGAAAGCCA TCTATGACAT GATGGGGAAA 
TACACCTATC CTGTGCTCAA AGAGGACACT CCCAGGCAGC ACGTGGACGT CTTCTTCCAG 
AAAATGGATA AAAATAAAGA TGGCATTGTA ACGTTAGACG AATTTCTCGA GTCCTGTCAG 
GAGGATGACA ACATCATGAG GTCTCTACAG CTGTTCCAAA ATGTCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248316.1
CDS	138..848
Translation	MSGCSKRCRLGFVKFAQTIFKLITGTLSKDIAWWYYQYQRDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM

Target ORF information:

RefSeq Version	NM_001261387.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261387.1

ORF Insert Sequence:

ATGAGCGGCT GCTCCAAAAG ATGCAGACTC GGGTTCGTGA AATTTGCCCA GACCATCTTT 
AAACTCATCA CCGGGACCCT CAGCAAAGAC ATCGCCTGGT GGTATTACCA GTATCAGAGA 
GACAAGATCG AGGATGATCT GGAGATGACC ATGGTTTGCC ATCGGCCTGA GGGACTGGAG 
CAGCTTGAGG CACAGACGAA CTTCACCAAG AGAGAACTGC AAGTCCTTTA CCGGGGATTC 
AAAAACGAGT GCCCCAGTGG TGTGGTTAAC GAAGAGACAT TCAAGCAGAT CTACGCTCAG 
TTTTTCCCTC ATGGAGATGC CAGCACATAC GCACATTACC TCTTCAATGC CTTCGACACC 
ACCCAGACAG GCTCTGTAAA GTTCGAGGAC TTTGTGACTG CTCTGTCGAT TTTACTGAGA 
GGAACGGTCC ATGAAAAACT GAGGTGGACG TTTAATTTGT ACGACATCAA TAAAGACGGC 
TACATAAACA AAGAGGAGAT GATGGACATA GTGAAAGCCA TCTATGACAT GATGGGGAAA 
TACACCTATC CTGTGCTCAA AGAGGACACT CCCAGGCAGC ACGTGGACGT CTTCTTCCAG 
AAAATGGATA AAAATAAAGA TGGCATTGTA ACGTTAGACG AATTTCTCGA GTCCTGTCAG 
GAGGATGACA ACATCATGAG GTCTCTACAG CTGTTCCAAA ATGTCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnip1 ( NM_001261388.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001248317.1 Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa09193
Clone ID Related Accession (Same CDS sequence)	NM_001261388.1
Accession Version	NM_001261388.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	Kv channel-interacting protein 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029266.1 and AABR07029260.1. Transcript Variant: This variant (2) lacks an exon in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C- termini compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAGCGGCT GCTCCAAAAG ATGCAGACTC GGGTTCGTGA AATTTGCCCA GACCATCTTT 
AAACTCATCA CCGGGACCCT CAGCAAAGAC AAGATCGAGG ATGATCTGGA GATGACCATG 
GTTTGCCATC GGCCTGAGGG ACTGGAGCAG CTTGAGGCAC AGACGAACTT CACCAAGAGA 
GAACTGCAAG TCCTTTACCG GGGATTCAAA AACGAGTGCC CCAGTGGTGT GGTTAACGAA 
GAGACATTCA AGCAGATCTA CGCTCAGTTT TTCCCTCATG GAGATGCCAG CACATACGCA 
CATTACCTCT TCAATGCCTT CGACACCACC CAGACAGGCT CTGTAAAGTT CGAGGACTTT 
GTGACTGCTC TGTCGATTTT ACTGAGAGGA ACGGTCCATG AAAAACTGAG GTGGACGTTT 
AATTTGTACG ACATCAATAA AGACGGCTAC ATAAACAAAG AGGAGATGAT GGACATAGTG 
AAAGCCATCT ATGACATGAT GGGGAAATAC ACCTATCCTG TGCTCAAAGA GGACACTCCC 
AGGCAGCACG TGGACGTCTT CTTCCAGAAA ATGGATAAAA ATAAAGATGG CATTGTAACG 
TTAGACGAAT TTCTCGAGTC CTGTCAGGAG GATGACAACA TCATGAGGTC TCTACAGCTG 
TTCCAAAATG TCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248317.1
CDS	138..815
Translation	MSGCSKRCRLGFVKFAQTIFKLITGTLSKDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM

Target ORF information:

RefSeq Version	NM_001261388.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261388.1

ORF Insert Sequence:

ATGAGCGGCT GCTCCAAAAG ATGCAGACTC GGGTTCGTGA AATTTGCCCA GACCATCTTT 
AAACTCATCA CCGGGACCCT CAGCAAAGAC AAGATCGAGG ATGATCTGGA GATGACCATG 
GTTTGCCATC GGCCTGAGGG ACTGGAGCAG CTTGAGGCAC AGACGAACTT CACCAAGAGA 
GAACTGCAAG TCCTTTACCG GGGATTCAAA AACGAGTGCC CCAGTGGTGT GGTTAACGAA 
GAGACATTCA AGCAGATCTA CGCTCAGTTT TTCCCTCATG GAGATGCCAG CACATACGCA 
CATTACCTCT TCAATGCCTT CGACACCACC CAGACAGGCT CTGTAAAGTT CGAGGACTTT 
GTGACTGCTC TGTCGATTTT ACTGAGAGGA ACGGTCCATG AAAAACTGAG GTGGACGTTT 
AATTTGTACG ACATCAATAA AGACGGCTAC ATAAACAAAG AGGAGATGAT GGACATAGTG 
AAAGCCATCT ATGACATGAT GGGGAAATAC ACCTATCCTG TGCTCAAAGA GGACACTCCC 
AGGCAGCACG TGGACGTCTT CTTCCAGAAA ATGGATAAAA ATAAAGATGG CATTGTAACG 
TTAGACGAAT TTCTCGAGTC CTGTCAGGAG GATGACAACA TCATGAGGTC TCTACAGCTG 
TTCCAAAATG TCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnip1 ( NM_001261389.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001248318.1 Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	ORa09196
Clone ID Related Accession (Same CDS sequence)	NM_001261389.1
Accession Version	NM_001261389.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	Kv channel-interacting protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029265.1 and AABR07029260.1. Transcript Variant: This variant (3) uses an alternate exon in the 5' coding region compared to variant 1. The resulting protein (isoform 3) has a distinct N-terminus and is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY082657.1, AY142709.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGGCCG TCATGGGTAC CTTCTCGTCC CTGCAGACCA AACAAAGGCG ACCCTCTAAA 
GACATCGCCT GGTGGTATTA CCAGTATCAG AGAGACAAGA TCGAGGATGA TCTGGAGATG 
ACCATGGTTT GCCATCGGCC TGAGGGACTG GAGCAGCTTG AGGCACAGAC GAACTTCACC 
AAGAGAGAAC TGCAAGTCCT TTACCGGGGA TTCAAAAACG AGTGCCCCAG TGGTGTGGTT 
AACGAAGAGA CATTCAAGCA GATCTACGCT CAGTTTTTCC CTCATGGAGA TGCCAGCACA 
TACGCACATT ACCTCTTCAA TGCCTTCGAC ACCACCCAGA CAGGCTCTGT AAAGTTCGAG 
GACTTTGTGA CTGCTCTGTC GATTTTACTG AGAGGAACGG TCCATGAAAA ACTGAGGTGG 
ACGTTTAATT TGTACGACAT CAATAAAGAC GGCTACATAA ACAAAGAGGA GATGATGGAC 
ATAGTGAAAG CCATCTATGA CATGATGGGG AAATACACCT ATCCTGTGCT CAAAGAGGAC 
ACTCCCAGGC AGCACGTGGA CGTCTTCTTC CAGAAAATGG ATAAAAATAA AGATGGCATT 
GTAACGTTAG ACGAATTTCT CGAGTCCTGT CAGGAGGATG ACAACATCAT GAGGTCTCTA 
CAGCTGTTCC AAAATGTCAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248318.1
CDS	1..684
Translation	MGAVMGTFSSLQTKQRRPSKDIAWWYYQYQRDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM

Target ORF information:

RefSeq Version	NM_001261389.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261389.1

ORF Insert Sequence:

ATGGGGGCCG TCATGGGTAC CTTCTCGTCC CTGCAGACCA AACAAAGGCG ACCCTCTAAA 
GACATCGCCT GGTGGTATTA CCAGTATCAG AGAGACAAGA TCGAGGATGA TCTGGAGATG 
ACCATGGTTT GCCATCGGCC TGAGGGACTG GAGCAGCTTG AGGCACAGAC GAACTTCACC 
AAGAGAGAAC TGCAAGTCCT TTACCGGGGA TTCAAAAACG AGTGCCCCAG TGGTGTGGTT 
AACGAAGAGA CATTCAAGCA GATCTACGCT CAGTTTTTCC CTCATGGAGA TGCCAGCACA 
TACGCACATT ACCTCTTCAA TGCCTTCGAC ACCACCCAGA CAGGCTCTGT AAAGTTCGAG 
GACTTTGTGA CTGCTCTGTC GATTTTACTG AGAGGAACGG TCCATGAAAA ACTGAGGTGG 
ACGTTTAATT TGTACGACAT CAATAAAGAC GGCTACATAA ACAAAGAGGA GATGATGGAC 
ATAGTGAAAG CCATCTATGA CATGATGGGG AAATACACCT ATCCTGTGCT CAAAGAGGAC 
ACTCCCAGGC AGCACGTGGA CGTCTTCTTC CAGAAAATGG ATAAAAATAA AGATGGCATT 
GTAACGTTAG ACGAATTTCT CGAGTCCTGT CAGGAGGATG ACAACATCAT GAGGTCTCTA 
CAGCTGTTCC AAAATGTCAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnip1 ( XM_006246105.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246167.1 Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant X1, mRNA.

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CloneID	ORa32951
Clone ID Related Accession (Same CDS sequence)	XM_006246105.3
Accession Version	XM_006246105.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	Kv channel-interacting protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246105.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGCCC GCGTTCTGCT TGCCTACCCG GGAACGGAGA TGTTGACCCA GGGCGAGTCT 
GAAGGGCTCC AGACCTTGGG GATAGTAGTG GTCCTGTGTT CCTCTCTGAA ACTACTGCAC 
TACCTCGGGC TGATTGACTT GTCGGATGAC AAGATCGAGG ATGATCTGGA GATGACCATG 
GTTTGCCATC GGCCTGAGGG ACTGGAGCAG CTTGAGGCAC AGACGAACTT CACCAAGAGA 
GAACTGCAAG TCCTTTACCG GGGATTCAAA AACGAGTGCC CCAGTGGTGT GGTTAACGAA 
GAGACATTCA AGCAGATCTA CGCTCAGTTT TTCCCTCATG GAGATGCCAG CACATACGCA 
CATTACCTCT TCAATGCCTT CGACACCACC CAGACAGGCT CTGTAAAGTT CGAGGACTTT 
GTGACTGCTC TGTCGATTTT ACTGAGAGGA ACGGTCCATG AAAAACTGAG GTGGACGTTT 
AATTTGTACG ACATCAATAA AGACGGCTAC ATAAACAAAG AGGAGATGAT GGACATAGTG 
AAAGCCATCT ATGACATGAT GGGGAAATAC ACCTATCCTG TGCTCAAAGA GGACACTCCC 
AGGCAGCACG TGGACGTCTT CTTCCAGAAA ATGGATAAAA ATAAAGATGG CATTGTAACG 
TTAGACGAAT TTCTCGAGTC CTGTCAGGAG GATGACAACA TCATGAGGTC TCTACAGCTG 
TTCCAAAATG TCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246167.1
CDS	946..1683
Translation	MPARVLLAYPGTEMLTQGESEGLQTLGIVVVLCSSLKLLHYLGLIDLSDDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM

Target ORF information:

RefSeq Version	XM_006246105.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel interacting protein 1 (Kcnip1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246105.3

ORF Insert Sequence:

ATGCCTGCCC GCGTTCTGCT TGCCTACCCG GGAACGGAGA TGTTGACCCA GGGCGAGTCT 
GAAGGGCTCC AGACCTTGGG GATAGTAGTG GTCCTGTGTT CCTCTCTGAA ACTACTGCAC 
TACCTCGGGC TGATTGACTT GTCGGATGAC AAGATCGAGG ATGATCTGGA GATGACCATG 
GTTTGCCATC GGCCTGAGGG ACTGGAGCAG CTTGAGGCAC AGACGAACTT CACCAAGAGA 
GAACTGCAAG TCCTTTACCG GGGATTCAAA AACGAGTGCC CCAGTGGTGT GGTTAACGAA 
GAGACATTCA AGCAGATCTA CGCTCAGTTT TTCCCTCATG GAGATGCCAG CACATACGCA 
CATTACCTCT TCAATGCCTT CGACACCACC CAGACAGGCT CTGTAAAGTT CGAGGACTTT 
GTGACTGCTC TGTCGATTTT ACTGAGAGGA ACGGTCCATG AAAAACTGAG GTGGACGTTT 
AATTTGTACG ACATCAATAA AGACGGCTAC ATAAACAAAG AGGAGATGAT GGACATAGTG 
AAAGCCATCT ATGACATGAT GGGGAAATAC ACCTATCCTG TGCTCAAAGA GGACACTCCC 
AGGCAGCACG TGGACGTCTT CTTCCAGAAA ATGGATAAAA ATAAAGATGG CATTGTAACG 
TTAGACGAAT TTCTCGAGTC CTGTCAGGAG GATGACAACA TCATGAGGTC TCTACAGCTG 
TTCCAAAATG TCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neuroprotective or neurotoxic effects of 4-aminopyridine mediated by KChIP1 regulation through adjustment of Kv 4.3 potassium channels expression and GABA-mediated transmission in primary hippocampal cells.
Toxicology333107-17(2015 Jul)
Del Pino J,Frejo MT,Baselga MJ,Capo MA,Moyano P,Garc?a JM,D?az MJ

Distribution and functional expression of Kv4 family ? subunits and associated KChIP ? subunits in the bed nucleus of the stria terminalis.
The Journal of comparative neurology522(3)609-25(2014 Feb)
Rainnie DG,Hazra R,Dabrowska J,Guo JD,Li CC,Dewitt S,Muly EC

Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.
Neuroscience171(3)721-33(2010 Dec)
Dabrowska J,Rainnie DG

The diversity of calcium sensor proteins in the regulation of neuronal function.
Cold Spring Harbor perspectives in biology2(8)a004085(2010 Aug)
McCue HV,Haynes LP,Burgoyne RD

Gene expression profiling in brain regions of a rat model displaying schizophrenia-related features.
Behavioural brain research207(2)476-9(2010 Mar)
Van Schijndel JE,Van Zweeden M,Van Loo KM,Martens GJ

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Kcnip1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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