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Home » Gene Synthesis & Molecular Biology Services » ORF » Hot Human pathways » SLC-mediated transmembrane transport

Overview

About the SLC-mediated transmembrane transport pathway

Proteins with transporting functions can be roughly classified into 3 categories: ATP-powered pumps, ion channels, and transporters. Pumps utilize the energy released by ATP hydrolysis to power the movement of the substrates across the membrane, against their electrochemical gradient. Channels at the open state can transfer the substrates (ions or water) down their electrochemical gradient, at an extremely high efficiency (up to 108 s-1). Transporters facilitate the movement of a specific substrate either against or following their concentration gradient, at a lower speed (about 102 -104 s-1); as generally believed, conformational change of the transporter protein is involved in the transfer process.

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.

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Gene Symbol Full Name
ALB albumin
APOD apolipoprotein D
AVP arginine vasopressin
RUNX1 runt-related transcription factor 1
SLC31A1 solute carrier family 31 (copper transporter), member 1
CP ceruloplasmin (ferroxidase)
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
CTNS cystinosin, lysosomal cystine transporter
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
G6PC glucose-6-phosphatase, catalytic subunit
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
GCK glucokinase (hexokinase 4)
GCKR glucokinase (hexokinase 4) regulator
HK1 hexokinase 1
HK2 hexokinase 2
HK3 hexokinase 3 (white cell)
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
LCN1 lipocalin 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
NUP88 nucleoporin 88kDa
NUP98 nucleoporin 98kDa
SLC22A18 solute carrier family 22, member 18
RANBP2 RAN binding protein 2
RHAG Rh-associated glycoprotein
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC17A1 solute carrier family 17 (organic anion transporter), member 1
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
TPR translocated promoter region, nuclear basket protein
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC39A7 solute carrier family 39 (zinc transporter), member 7
NUP214 nucleoporin 214kDa
AAAS achalasia, adrenocortical insufficiency, alacrimia
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC14A2 solute carrier family 14 (urea transporter), member 2
RAE1 ribonucleic acid export 1

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