Gene Symbol | MAPK3 |
Entrez Gene ID | 531391 |
Full Name | mitogen-activated protein kinase 3 |
Synonyms | ERK1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » MAPK3 cDNA ORF clone
Gene Symbol | MAPK3 |
Entrez Gene ID | 531391 |
Full Name | mitogen-activated protein kinase 3 |
Synonyms | ERK1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005224919.4 | XP_005224976.1 | mitogen-activated protein kinase 3 isoform X1 |
NM_001110018.1 | NP_001103488.1 | mitogen-activated protein kinase 3 |
XM_005224919.3 | XP_005224976.1 | mitogen-activated protein kinase 3 isoform X1 |
Pan troglodytes (chimpanzee) | MAPK3 | XP_510921.3 |
Canis lupus familiaris (dog) | LOC479790 | NP_001238964.1 |
Bos taurus (cattle) | MAPK3 | NP_001103488.1 |
Danio rerio (zebrafish) | mapk3 | NP_958915.1 |
Arabidopsis thaliana (thale cress) | MPK2 | NP_564746.1 |
Oryza sativa (rice) | Os02g0148100 | NP_001045889.1 |
Rattus norvegicus (Norway rat) | Mapk3 | NP_059043.1 |
Arabidopsis thaliana (thale cress) | MPK1 | NP_001031017.1 |
MAPK3 | XP_002802489.1 | |
Mus musculus (house mouse) | Mapk3 | NP_036082.1 |
Eremothecium gossypii | AGOS_AFR019W | NP_985566.1 |
Neurospora crassa | NCU02393 | XP_959713.2 |
Oryza sativa (rice) | Os06g0699400 | NP_001058471.1 |
Saccharomyces cerevisiae (baker's yeast) | FUS3 | NP_009537.1 |
Homo sapiens (human) | MAPK3 | NP_002737.2 |
Kluyveromyces lactis | KLLA0E10539g | XP_454426.1 |
Schizosaccharomyces pombe (fission yeast) | spk1 | NP_594009.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_09565 | XP_003712175.1 |
MAPK3/1 is conducive to luteinizing hormone-mediated C-type natriuretic peptide decrease in bovine granulosa cells.
Yang L, Wei Q, Ge J, Zhao X, Ma B
The Journal of reproduction and development62(2)137-42(2016 Apr)
Endoplasmic reticulum Ca2+ release modulates endothelial nitric-oxide synthase via extracellular signal-regulated kinase (ERK) 1/2-mediated serine 635 phosphorylation.
Xiao Z, Wang T, Qin H, Huang C, Feng Y, Xia Y
The Journal of biological chemistry286(22)20100-8(2011 Jun)
Thrombospondin 1, fibronectin, and vitronectin are differentially dependent upon RAS, ERK1/2, and p38 for induction of vascular smooth muscle cell chemotaxis.
Willis AI, Sadowitz B, Fuse S, Maier KG, Lee TS, Wang XJ, Tuszynski GP, Sumpio BE, Gahtan V
Vascular and endovascular surgery45(1)55-62(2011 Jan)
Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia.
Hartney T, Birari R, Venkataraman S, Villegas L, Martinez M, Black SM, Stenmark KR, Nozik-Grayck E
PloS one6(11)e27531(2011)
Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38.
Nemoto T, Miyazaki S, Kanai T, Maruta T, Satoh S, Yoshikawa N, Yanagita T, Wada A
European journal of pharmacology640(1-3)20-8(2010 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
MAPK3/1 is involved in luteinizing hormone-mediated decrease of C-type natriuretic peptide and this process is related to the EGFR and MAPK3/1 signal pathways
Title: MAPK3/1 is conducive to luteinizing hormone-mediated C-type natriuretic peptide decrease in bovine granulosa cells.
ER Ca(2+) release enhances eNOS Ser-635 phosphorylation and function via ERK1/2 activation.
Title: Endoplasmic reticulum Ca2+ release modulates endothelial nitric-oxide synthase via extracellular signal-regulated kinase (ERK) 1/2-mediated serine 635 phosphorylation.
Thrombospondin 1, fibronectin, and vitronectin are differentially dependent upon RAS, ERK1/2, and p38 for induction of vascular smooth muscle cell chemotaxis.
Title: Thrombospondin 1, fibronectin, and vitronectin are differentially dependent upon RAS, ERK1/2, and p38 for induction of vascular smooth muscle cell chemotaxis.
Chronic hypoxia induces Egr-1 via activation of ERK1/2 and contributes to pulmonary vascular remodeling.
Title: Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia.
results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation
Title: Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38.
The following MAPK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAPK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01825 | |
Clone ID Related Accession (Same CDS sequence) | NM_001110018.1 | |
Accession Version | NM_001110018.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-28 | |
Organism | Bos taurus(cattle) | |
Product | mitogen-activated protein kinase 3 | |
Comment | Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from NKLS02000025.1. On Oct 20, 2007 this sequence version replaced XM_609884.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGAGATAG TAAAGGGGCA GCCGTTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001103488.1 |
CDS | 1..1089 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001110018.1 |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGAGATAG TAAAGGGGCA GCCGTTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa33105 | |
Clone ID Related Accession (Same CDS sequence) | XM_005224919.4 , XM_005224919.3 | |
Accession Version | XM_005224919.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | mitogen-activated protein kinase 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037352.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005224919.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGGCGGGG AGCCCCGGGG AACTGATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005224976.1 |
CDS | 13..1155 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005224919.4 |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGGCGGGG AGCCCCGGGG AACTGATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa33105 | |
Clone ID Related Accession (Same CDS sequence) | XM_005224919.4 , XM_005224919.3 | |
Accession Version | XM_005224919.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | mitogen-activated protein kinase 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005224919.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGGCGGGG AGCCCCGGGG AACTGATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005224976.1 |
CDS | 11..1153 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005224919.3 |
1 | ATGGCGGCGG CGGCGGCGGC TCAGGGGGGC GGGGGCGGGG AGCCCCGGGG AACTGATGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
MAPK3/1 is conducive to luteinizing hormone-mediated C-type natriuretic peptide decrease in bovine granulosa cells. |
Endoplasmic reticulum Ca2+ release modulates endothelial nitric-oxide synthase via extracellular signal-regulated kinase (ERK) 1/2-mediated serine 635 phosphorylation. |
Thrombospondin 1, fibronectin, and vitronectin are differentially dependent upon RAS, ERK1/2, and p38 for induction of vascular smooth muscle cell chemotaxis. |
Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia. |
Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38. |