esama cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	esama
Entrez Gene ID	799432
Full Name	endothelial cell adhesion molecule a
Synonyms	ESAM,sc:d0254
General protein information	Preferred Names endothelial cell adhesion molecule a Names endothelial cell-selective adhesion molecule endothelial cell-specific adhesion molecule zESAMa
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001115066.1	NP_001108538.1	endothelial cell-selective adhesion molecule precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ESAM	NP_001071534.1
Gallus gallus (chicken)	ESAM	XP_417851.4
Pan troglodytes (chimpanzee)	ESAM	XP_508839.1
Canis lupus familiaris (dog)	ESAM	XP_546427.2
Rattus norvegicus (Norway rat)	Esam	NP_001004245.1
Danio rerio (zebrafish)	esama	NP_001108538.1
Danio rerio (zebrafish)	LOC562934	XP_691391.5
Xenopus tropicalis (tropical clawed frog)	esam	NP_001135525.1
Homo sapiens (human)	ESAM	NP_620411.2
	ESAM	XP_001110293.1
Mus musculus (house mouse)	Esam	NP_081378.1

Gene Ontology
Bibliography

Related articles in PubMed

Distinct and redundant functions of Esama and VE-cadherin during vascular morphogenesis.
Sauteur L, Affolter M, Belting HG
Development (Cambridge, England)144(8)1554-1565(2017 04)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Cdh5/VE-cadherin promotes endothelial cell interface elongation via cortical actin polymerization during angiogenic sprouting.
Sauteur L, Krudewig A, Herwig L, Ehrenfeuchter N, Lenard A, Affolter M, Belting HG
Cell reports9(2)504-13(2014 Oct)

Hyaluronic acid receptor Stabilin-2 regulates Erk phosphorylation and arterial--venous differentiation in zebrafish.
Rost MS, Sumanas S
PloS one9(2)e88614(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

VE-cadherin and Esama have distinct and redundant functions during blood vessel morphogenesis
Title: Distinct and redundant functions of Esama and VE-cadherin during vascular morphogenesis.

The following esama gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the esama cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa34076	NM_001115066.1 Latest version!	Danio rerio endothelial cell adhesion molecule a (esama), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

esama ( NM_001115066.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001108538.1 Danio rerio endothelial cell adhesion molecule a (esama), mRNA.

Price & Availability↑

CloneID	ODa34076
Clone ID Related Accession (Same CDS sequence)	NM_001115066.1
Accession Version	NM_001115066.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1287bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Danio rerio(zebrafish)
Product	endothelial cell-selective adhesion molecule precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CU638747.1. On Mar 2, 2008 this sequence version replaced XM_001339751.1. ##Evidence-Data-START## Transcript exon combination :: CU638747.1, FJ205704.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAGAC GAACTTCAAC AAAATTTCAC AACTACCTGT CAATATTCAC GTTTCTCTGC 
TGTTTCTCAT CAGGTGAGCT GGCCCAACTT GTGTTGCCTT ATGAAAATGT GGATGTGATC 
CAAGGGAAGA TGGTGGTGCT GCAGGCTTCA TATTCGAGTA CGGACTTTCA GAAAAACACA 
GTCGTCTGGA ACTACATGCA GTCTGCTACC AGCACTGAAA TGATTATCTC ATTCGTCAAT 
GGAGACTTCA GCCATGGCAC CTCACAGTTT GCTGGTCGAG TTGGTTTTTT CCACAATATG 
CCCAACACCA ACCTGTCCCT GTACATTAAC AACACCAAAG TATCAGACTC AGGGCGGTAC 
GTGTGCCAGG TCATGATCCC CGGGGCCTCA GGACTCACTG GAACACTAAA CCTTAATGTT 
AAAGTACCTC CTTCTATACC AGTGTGTAAG GTTAAAGAAA AGCCTGTCCT TAAAGCAAAC 
ATTACTCTTT CCTGTAACTC CAATGAGGGT AAACCGGCCC CCAAATACAA GTGGATCAAA 
ACCAGCCCCA CATCAGAGGT CTTCTTCTCT CCTGCATTGA ATGAAACGGC AGGAACTTTA 
AAACTGAACA ACCTAAGCAG TAACATGTCA GGGAAATATG TGTGCACTTC AACCAACTCT 
GCAGGAGAGG AGACCTGCTA CATCAACCTG GAGGTCATCA CATCGACAAA TGCCGGAATG 
ATCGCTGGCG TTACATTCGG CTGTATAGTG GCTCTCATCC TGATCGTTAT CTTCCTCATC 
TTCATGTGGA CGAGACGGAA AGACACCGAG GAGGATCTGG CCAATGACAT CAAGGAGGAT 
GCTCAGGCTC CCAAACGCGT CTCGTGGGCC AAGAGTGGCA CAGGCTCTGA CATCATCTCT 
AAAAACGGCA CCCTGTCCTC CATTCACACC AGCTCTTACC CACGAGATGC CCACAACCAC 
CATCATTACC CTCACTCCGA CACCGCGTCC ATTATTACAG CCACAGGCAG CACAGCCGGA 
TACCGTTCGC AACCTCCAGT CGATGCCACC CTGGAGCGCT CATTGCCAGG ATACAACACC 
AACCCAGCCC CGACCCGTGG GCCATTTGGA CCCCCTAGTA CCAATGGAGG CTCCCAGCAC 
ACCTCCATGC CCCGGACAGC CCCTGCCCAG CCTCAGATTC CCCGTCCGCC TGTCCTCCCC 
ACCACCGTAA CTGCTGCCAA TATCTCCCGC ATGGGAGGGG TGCCCATTAT GGTGCCAGCA 
CAAAACCAAG CCGGCTCTCT GGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001108538.1
CDS	62..1348
Translation	MERRTSTKFHNYLSIFTFLCCFSSGELAQLVLPYENVDVIQGKMVVLQASYSSTDFQKNTVVWNYMQSATSTEMIISFVNGDFSHGTSQFAGRVGFFHNMPNTNLSLYINNTKVSDSGRYVCQVMIPGASGLTGTLNLNVKVPPSIPVCKVKEKPVLKANITLSCNSNEGKPAPKYKWIKTSPTSEVFFSPALNETAGTLKLNNLSSNMSGKYVCTSTNSAGEETCYINLEVITSTNAGMIAGVTFGCIVALILIVIFLIFMWTRRKDTEEDLANDIKEDAQAPKRVSWAKSGTGSDIISKNGTLSSIHTSSYPRDAHNHHHYPHSDTASIITATGSTAGYRSQPPVDATLERSLPGYNTNPAPTRGPFGPPSTNGGSQHTSMPRTAPAQPQIPRPPVLPTTVTAANISRMGGVPIMVPAQNQAGSLV

Target ORF information:

RefSeq Version	NM_001115066.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio endothelial cell adhesion molecule a (esama), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001115066.1

ORF Insert Sequence:

ATGGAGAGAC GAACTTCAAC AAAATTTCAC AACTACCTGT CAATATTCAC GTTTCTCTGC 
TGTTTCTCAT CAGGTGAGCT GGCCCAACTT GTGTTGCCTT ATGAAAATGT GGATGTGATC 
CAAGGGAAGA TGGTGGTGCT GCAGGCTTCA TATTCGAGTA CGGACTTTCA GAAAAACACA 
GTCGTCTGGA ACTACATGCA GTCTGCTACC AGCACTGAAA TGATTATCTC ATTCGTCAAT 
GGAGACTTCA GCCATGGCAC CTCACAGTTT GCTGGTCGAG TTGGTTTTTT CCACAATATG 
CCCAACACCA ACCTGTCCCT GTACATTAAC AACACCAAAG TATCAGACTC AGGGCGGTAC 
GTGTGCCAGG TCATGATCCC CGGGGCCTCA GGACTCACTG GAACACTAAA CCTTAATGTT 
AAAGTACCTC CTTCTATACC AGTGTGTAAG GTTAAAGAAA AGCCTGTCCT TAAAGCAAAC 
ATTACTCTTT CCTGTAACTC CAATGAGGGT AAACCGGCCC CCAAATACAA GTGGATCAAA 
ACCAGCCCCA CATCAGAGGT CTTCTTCTCT CCTGCATTGA ATGAAACGGC AGGAACTTTA 
AAACTGAACA ACCTAAGCAG TAACATGTCA GGGAAATATG TGTGCACTTC AACCAACTCT 
GCAGGAGAGG AGACCTGCTA CATCAACCTG GAGGTCATCA CATCGACAAA TGCCGGAATG 
ATCGCTGGCG TTACATTCGG CTGTATAGTG GCTCTCATCC TGATCGTTAT CTTCCTCATC 
TTCATGTGGA CGAGACGGAA AGACACCGAG GAGGATCTGG CCAATGACAT CAAGGAGGAT 
GCTCAGGCTC CCAAACGCGT CTCGTGGGCC AAGAGTGGCA CAGGCTCTGA CATCATCTCT 
AAAAACGGCA CCCTGTCCTC CATTCACACC AGCTCTTACC CACGAGATGC CCACAACCAC 
CATCATTACC CTCACTCCGA CACCGCGTCC ATTATTACAG CCACAGGCAG CACAGCCGGA 
TACCGTTCGC AACCTCCAGT CGATGCCACC CTGGAGCGCT CATTGCCAGG ATACAACACC 
AACCCAGCCC CGACCCGTGG GCCATTTGGA CCCCCTAGTA CCAATGGAGG CTCCCAGCAC 
ACCTCCATGC CCCGGACAGC CCCTGCCCAG CCTCAGATTC CCCGTCCGCC TGTCCTCCCC 
ACCACCGTAA CTGCTGCCAA TATCTCCCGC ATGGGAGGGG TGCCCATTAT GGTGCCAGCA 
CAAAACCAAG CCGGCTCTCT GGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Distinct and redundant functions of Esama and VE-cadherin during vascular morphogenesis.
Development (Cambridge, England)144(8)1554-1565(2017 04)
Sauteur L,Affolter M,Belting HG

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Cdh5/VE-cadherin promotes endothelial cell interface elongation via cortical actin polymerization during angiogenic sprouting.
Cell reports9(2)504-13(2014 Oct)
Sauteur L,Krudewig A,Herwig L,Ehrenfeuchter N,Lenard A,Affolter M,Belting HG

Hyaluronic acid receptor Stabilin-2 regulates Erk phosphorylation and arterial--venous differentiation in zebrafish.
PloS one9(2)e88614(2014)
Rost MS,Sumanas S