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SERPINB9 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol SERPINB9
Entrez Gene ID 5272
Full Name serpin family B member 9
Synonyms CAP-3,CAP3,PI-9,PI9
General protein information
Preferred Names

serpin family B member 9

Names

serpin B9
cytoplasmic antiproteinase 3
peptidase inhibitor 9
protease inhibitor 9 (ovalbumin type)
serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
serpin peptidase inhibitor, clade B, member 9
testicular tissue protein Li 180
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

6

6p25.2
Summary This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012].
Disorder MIM:

601799


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_005249184.4 XP_005249241.1 serpin B9 isoform X1
XM_005249184.3 XP_005249241.1 serpin B9 isoform X1
XM_005249184.5 XP_005249241.1 serpin B9 isoform X1
XM_017010943.1 XP_016866432.1 serpin B9 isoform X2
NM_004155.5 NP_004146.1 serpin B9
XM_017010942.1 XP_016866431.1 serpin B9 isoform X2
NM_004155.6 NP_004146.1 serpin B9
XM_011514678.2 XP_011512980.1 serpin B9 isoform X2

Pathways from BioSystems


Homologies


Homo sapiens (human) SERPINB9 NP_004146.1
SERPINB9 XP_001091156.1
Canis lupus familiaris (dog) SERPINB9 XP_005640036.1
Mus musculus (house mouse) Serpinb9 NP_033282.1
Rattus norvegicus (Norway rat) Serpinb9 NP_001007733.1
Pan troglodytes (chimpanzee) SERPINB9 XP_001160054.1
Bos taurus (cattle) SERPINB9 NP_001069327.1

Gene Ontology


Bibliography

Related articles in PubMed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Glavey SV, Naba A, Manier S, Clauser K, Tahri S, Park J, Reagan MR, Moschetta M, Mishima Y, Gambella M, Rocci A, Sacco A, O'Dwyer ME, Asara JM, Palumbo A, Roccaro AM, Hynes RO, Ghobrial IM
Leukemia31(11)2426-2434(2017 Nov)

The analysis of estrogen receptor-? positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms.
Lauricella M, Carlisi D, Giuliano M, Calvaruso G, Cernigliaro C, Vento R, D'Anneo A
International journal of oncology49(1)352-60(2016 Jul)

Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors.
van Kempen PM, Noorlag R, Swartz JE, Bovenschen N, Braunius WW, Vermeulen JF, Van Cann EM, Grolman W, Willems SM
Cancer immunology, immunotherapy : CII65(5)575-85(2016 May)

Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease.
van der Burgh R, Meeldijk J, Jongeneel L, Frenkel J, Bovenschen N, van Gijn M, Boes M
Oncotarget7(15)19265-71(2016 Apr)

Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors.
Vermeulen JF, van Hecke W, Spliet WG, Villacorta Hidalgo J, Fisch P, Broekhuizen R, Bovenschen N
PloS one11(3)e0151465(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Treatment with estrogens further increased PI-9 level while decreased that of ERalpha66 isoform thus excluding the involvement of this receptor isoform in the event. Moreover, our studies also provided evidence that tertiary tumorspheres express elevated levels of CXCR4 and phospho-p38, suggesting that the high PI-9 content might be ascribed to the activation of the proliferative CXCR4/phospho-p38 axis.
Title: The analysis of estrogen receptor-? positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms.

Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1, SERPINB4 and SERPINB9 for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.
Title: Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors.

Data show that the serine protease inhibitor B9 (serpinB9) mediated caspase-1 inhibition regulates IL-1beta release in monocytes.
Title: Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease.

Data suggest that reactive oxygen species (ROS) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B) into the cytosol and for inactivation of serpin B9.
Title: A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOP.

Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC-I and CD1d expression. Intriguingly, expression of SERPINB9, SERPINB1, and SERPINB4 is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors
Title: Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors.

The following SERPINB9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SERPINB9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu01596 NM_004155.6
Latest version!		 Homo sapiens serpin family B member 9 (SERPINB9), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu01596 XM_005249184.5
Latest version!		 Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu59678 XM_017010943.1
Latest version!		 Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu59678 XM_011514678.2
Latest version!		 Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu59678 XM_017010942.1
Latest version!		 Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
View Old Accession Versions >>
OHu01596 XM_005249184.3 Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 9 (SERPINB9), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu01596 XM_005249184.4 Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
OHu01596 NM_004155.5 Homo sapiens serpin family B member 9 (SERPINB9), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu01596
Clone ID Related Accession (Same CDS sequence) XM_005249184.4 , XM_005249184.3 , XM_005249184.5 , NM_004155.5 , NM_004155.6
Accession Version NM_004155.5 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1131bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-12-05
Organism Homo sapiens(human)
Product serpin B9
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL133351.34, BC002538.2 and BX485378.1. On Mar 14, 2012 this sequence version replaced NM_004155.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC002538.2, SRR1803611.155048.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_004146.1
CDS123..1253
Translation

Target ORF information:

RefSeq Version NM_004155.5
Organism Homo sapiens(human)
Definition Homo sapiens serpin family B member 9 (SERPINB9), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_004155.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu01596
Clone ID Related Accession (Same CDS sequence) XM_005249184.4 , XM_005249184.3 , XM_005249184.5 , NM_004155.5 , NM_004155.6
Accession Version NM_004155.6 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1131bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-23
Organism Homo sapiens(human)
Product serpin B9
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL133351.34, BC002538.2 and BX485378.1. On Nov 22, 2018 this sequence version replaced NM_004155.5. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC002538.2, SRR1660805.99844.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000380698.5/ ENSP00000370074.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_004146.1
CDS120..1250
Translation

Target ORF information:

RefSeq Version NM_004155.6
Organism Homo sapiens(human)
Definition Homo sapiens serpin family B member 9 (SERPINB9), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_004155.6

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu01596
Clone ID Related Accession (Same CDS sequence) XM_005249184.4 , XM_005249184.3 , XM_005249184.5 , NM_004155.5 , NM_004155.6
Accession Version XM_005249184.4 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1131bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product serpin B9 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249184.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005249241.1
CDS286..1416
Translation

Target ORF information:

RefSeq Version XM_005249184.4
Organism Homo sapiens(human)
Definition Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005249184.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu01596
Clone ID Related Accession (Same CDS sequence) XM_005249184.4 , XM_005249184.3 , XM_005249184.5 , NM_004155.5 , NM_004155.6
Accession Version XM_005249184.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1131bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-03-11
Organism Homo sapiens(Human)
Product serpin B9 isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005249241.1
Translation

Target ORF information:

RefSeq Version XM_005249184.3
Organism Homo sapiens(Human)
Definition Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 9 (SERPINB9), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005249184.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu01596
Clone ID Related Accession (Same CDS sequence) XM_005249184.4 , XM_005249184.3 , XM_005249184.5 , NM_004155.5 , NM_004155.6
Accession Version XM_005249184.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1131bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product serpin B9 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005249184.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005249241.1
CDS286..1416
Translation

Target ORF information:

RefSeq Version XM_005249184.5
Organism Homo sapiens(human)
Definition Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005249184.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGAAACTC TTTCTAATGC AAGTGGTACT TTTGCCATAC GCCTTTTAAA GATACTGTGT 
CAAGATAACC CTTCGCACAA CGTGTTCTGT TCTCCTGTGA GCATCTCCTC TGCCCTGGCC 
ATGGTTCTCC TAGGGGCAAA GGGAAACACC GCAACCCAGA TGGCCCAGGC ACTGTCTTTA 
AACACAGAGG AAGACATTCA TCGGGCTTTC CAGTCGCTTC TCACTGAAGT GAACAAGGCT 
GGCACACAGT ACCTGCTGAG AACGGCCAAC AGGCTCTTTG GAGAGAAAAC TTGTCAGTTC 
CTCTCAACGT TTAAGGAATC CTGTCTTCAA TTCTACCATG CTGAGCTGAA GGAGCTTTCC 
TTTATCAGAG CTGCAGAAGA GTCCAGGAAA CACATCAACA CCTGGGTCTC AAAAAAGACC 
GAAGGTAAAA TTGAAGAGTT GTTGCCGGGT AGCTCAATTG ATGCAGAAAC CAGGCTGGTT 
CTTGTCAATG CCATCTACTT CAAAGGAAAG TGGAATGAAC CGTTTGACGA AACATACACA 
AGGGAAATGC CCTTTAAAAT AAACCAGGAG GAGCAAAGGC CAGTGCAGAT GATGTATCAG 
GAGGCCACGT TTAAGCTCGC CCACGTGGGC GAGGTGCGCG CGCAGCTGCT GGAGCTGCCC 
TACGCCAGGA AGGAGCTGAG CCTGCTGGTG CTGCTGCCTG ACGACGGCGT GGAGCTCAGC 
ACGGTGGAAA AAAGTCTCAC TTTTGAGAAA CTCACAGCCT GGACCAAGCC AGACTGTATG 
AAGAGTACTG AGGTTGAAGT TCTCCTTCCA AAATTTAAAC TACAAGAGGA TTATGACATG 
GAATCTGTGC TTCGGCATTT GGGAATTGTT GATGCCTTCC AACAGGGCAA GGCTGACTTG 
TCGGCAATGT CAGCGGAGAG AGACCTGTGT CTGTCCAAGT TCGTGCACAA GAGTTTTGTG 
GAGGTGAATG AAGAAGGCAC CGAGGCAGCG GCAGCGTCGA GCTGCTTTGT AGTTGCAGAG 
TGCTGCATGG AATCTGGCCC CAGGTTCTGT GCTGACCACC CTTTCCTTTT CTTCATCAGG 
CACAACAGAG CCAACAGCAT TCTGTTCTGT GGCAGGTTCT CATCGCCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu59678
Clone ID Related Accession (Same CDS sequence) XM_017010943.1 , XM_017010942.1 , XM_011514678.2
Accession Version XM_017010943.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 978bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product serpin B9 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCACCAT GCCTGGCACT GTCTTTAAAC ACAGAGGAAG ACATTCATCG GGCTTTCCAG 
TCGCTTCTCA CTGAAGTGAA CAAGGCTGGC ACACAGTACC TGCTGAGAAC GGCCAACAGG 
CTCTTTGGAG AGAAAACTTG TCAGTTCCTC TCAACGTTTA AGGAATCCTG TCTTCAATTC 
TACCATGCTG AGCTGAAGGA GCTTTCCTTT ATCAGAGCTG CAGAAGAGTC CAGGAAACAC 
ATCAACACCT GGGTCTCAAA AAAGACCGAA GGTAAAATTG AAGAGTTGTT GCCGGGTAGC 
TCAATTGATG CAGAAACCAG GCTGGTTCTT GTCAATGCCA TCTACTTCAA AGGAAAGTGG 
AATGAACCGT TTGACGAAAC ATACACAAGG GAAATGCCCT TTAAAATAAA CCAGGAGGAG 
CAAAGGCCAG TGCAGATGAT GTATCAGGAG GCCACGTTTA AGCTCGCCCA CGTGGGCGAG 
GTGCGCGCGC AGCTGCTGGA GCTGCCCTAC GCCAGGAAGG AGCTGAGCCT GCTGGTGCTG 
CTGCCTGACG ACGGCGTGGA GCTCAGCACG GTGGAAAAAA GTCTCACTTT TGAGAAACTC 
ACAGCCTGGA CCAAGCCAGA CTGTATGAAG AGTACTGAGG TTGAAGTTCT CCTTCCAAAA 
TTTAAACTAC AAGAGGATTA TGACATGGAA TCTGTGCTTC GGCATTTGGG AATTGTTGAT 
GCCTTCCAAC AGGGCAAGGC TGACTTGTCG GCAATGTCAG CGGAGAGAGA CCTGTGTCTG 
TCCAAGTTCG TGCACAAGAG TTTTGTGGAG GTGAATGAAG AAGGCACCGA GGCAGCGGCA 
GCGTCGAGCT GCTTTGTAGT TGCAGAGTGC TGCATGGAAT CTGGCCCCAG GTTCTGTGCT 
GACCACCCTT TCCTTTTCTT CATCAGGCAC AACAGAGCCA ACAGCATTCT GTTCTGTGGC 
AGGTTCTCAT CGCCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016866432.1
CDS584..1561
Translation

Target ORF information:

RefSeq Version XM_017010943.1
Organism Homo sapiens(human)
Definition Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017010943.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCACCAT GCCTGGCACT GTCTTTAAAC ACAGAGGAAG ACATTCATCG GGCTTTCCAG 
TCGCTTCTCA CTGAAGTGAA CAAGGCTGGC ACACAGTACC TGCTGAGAAC GGCCAACAGG 
CTCTTTGGAG AGAAAACTTG TCAGTTCCTC TCAACGTTTA AGGAATCCTG TCTTCAATTC 
TACCATGCTG AGCTGAAGGA GCTTTCCTTT ATCAGAGCTG CAGAAGAGTC CAGGAAACAC 
ATCAACACCT GGGTCTCAAA AAAGACCGAA GGTAAAATTG AAGAGTTGTT GCCGGGTAGC 
TCAATTGATG CAGAAACCAG GCTGGTTCTT GTCAATGCCA TCTACTTCAA AGGAAAGTGG 
AATGAACCGT TTGACGAAAC ATACACAAGG GAAATGCCCT TTAAAATAAA CCAGGAGGAG 
CAAAGGCCAG TGCAGATGAT GTATCAGGAG GCCACGTTTA AGCTCGCCCA CGTGGGCGAG 
GTGCGCGCGC AGCTGCTGGA GCTGCCCTAC GCCAGGAAGG AGCTGAGCCT GCTGGTGCTG 
CTGCCTGACG ACGGCGTGGA GCTCAGCACG GTGGAAAAAA GTCTCACTTT TGAGAAACTC 
ACAGCCTGGA CCAAGCCAGA CTGTATGAAG AGTACTGAGG TTGAAGTTCT CCTTCCAAAA 
TTTAAACTAC AAGAGGATTA TGACATGGAA TCTGTGCTTC GGCATTTGGG AATTGTTGAT 
GCCTTCCAAC AGGGCAAGGC TGACTTGTCG GCAATGTCAG CGGAGAGAGA CCTGTGTCTG 
TCCAAGTTCG TGCACAAGAG TTTTGTGGAG GTGAATGAAG AAGGCACCGA GGCAGCGGCA 
GCGTCGAGCT GCTTTGTAGT TGCAGAGTGC TGCATGGAAT CTGGCCCCAG GTTCTGTGCT 
GACCACCCTT TCCTTTTCTT CATCAGGCAC AACAGAGCCA ACAGCATTCT GTTCTGTGGC 
AGGTTCTCAT CGCCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu59678
Clone ID Related Accession (Same CDS sequence) XM_017010943.1 , XM_017010942.1 , XM_011514678.2
Accession Version XM_017010942.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 978bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product serpin B9 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCACCAT GCCTGGCACT GTCTTTAAAC ACAGAGGAAG ACATTCATCG GGCTTTCCAG 
TCGCTTCTCA CTGAAGTGAA CAAGGCTGGC ACACAGTACC TGCTGAGAAC GGCCAACAGG 
CTCTTTGGAG AGAAAACTTG TCAGTTCCTC TCAACGTTTA AGGAATCCTG TCTTCAATTC 
TACCATGCTG AGCTGAAGGA GCTTTCCTTT ATCAGAGCTG CAGAAGAGTC CAGGAAACAC 
ATCAACACCT GGGTCTCAAA AAAGACCGAA GGTAAAATTG AAGAGTTGTT GCCGGGTAGC 
TCAATTGATG CAGAAACCAG GCTGGTTCTT GTCAATGCCA TCTACTTCAA AGGAAAGTGG 
AATGAACCGT TTGACGAAAC ATACACAAGG GAAATGCCCT TTAAAATAAA CCAGGAGGAG 
CAAAGGCCAG TGCAGATGAT GTATCAGGAG GCCACGTTTA AGCTCGCCCA CGTGGGCGAG 
GTGCGCGCGC AGCTGCTGGA GCTGCCCTAC GCCAGGAAGG AGCTGAGCCT GCTGGTGCTG 
CTGCCTGACG ACGGCGTGGA GCTCAGCACG GTGGAAAAAA GTCTCACTTT TGAGAAACTC 
ACAGCCTGGA CCAAGCCAGA CTGTATGAAG AGTACTGAGG TTGAAGTTCT CCTTCCAAAA 
TTTAAACTAC AAGAGGATTA TGACATGGAA TCTGTGCTTC GGCATTTGGG AATTGTTGAT 
GCCTTCCAAC AGGGCAAGGC TGACTTGTCG GCAATGTCAG CGGAGAGAGA CCTGTGTCTG 
TCCAAGTTCG TGCACAAGAG TTTTGTGGAG GTGAATGAAG AAGGCACCGA GGCAGCGGCA 
GCGTCGAGCT GCTTTGTAGT TGCAGAGTGC TGCATGGAAT CTGGCCCCAG GTTCTGTGCT 
GACCACCCTT TCCTTTTCTT CATCAGGCAC AACAGAGCCA ACAGCATTCT GTTCTGTGGC 
AGGTTCTCAT CGCCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016866431.1
CDS426..1403
Translation

Target ORF information:

RefSeq Version XM_017010942.1
Organism Homo sapiens(human)
Definition Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017010942.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCACCAT GCCTGGCACT GTCTTTAAAC ACAGAGGAAG ACATTCATCG GGCTTTCCAG 
TCGCTTCTCA CTGAAGTGAA CAAGGCTGGC ACACAGTACC TGCTGAGAAC GGCCAACAGG 
CTCTTTGGAG AGAAAACTTG TCAGTTCCTC TCAACGTTTA AGGAATCCTG TCTTCAATTC 
TACCATGCTG AGCTGAAGGA GCTTTCCTTT ATCAGAGCTG CAGAAGAGTC CAGGAAACAC 
ATCAACACCT GGGTCTCAAA AAAGACCGAA GGTAAAATTG AAGAGTTGTT GCCGGGTAGC 
TCAATTGATG CAGAAACCAG GCTGGTTCTT GTCAATGCCA TCTACTTCAA AGGAAAGTGG 
AATGAACCGT TTGACGAAAC ATACACAAGG GAAATGCCCT TTAAAATAAA CCAGGAGGAG 
CAAAGGCCAG TGCAGATGAT GTATCAGGAG GCCACGTTTA AGCTCGCCCA CGTGGGCGAG 
GTGCGCGCGC AGCTGCTGGA GCTGCCCTAC GCCAGGAAGG AGCTGAGCCT GCTGGTGCTG 
CTGCCTGACG ACGGCGTGGA GCTCAGCACG GTGGAAAAAA GTCTCACTTT TGAGAAACTC 
ACAGCCTGGA CCAAGCCAGA CTGTATGAAG AGTACTGAGG TTGAAGTTCT CCTTCCAAAA 
TTTAAACTAC AAGAGGATTA TGACATGGAA TCTGTGCTTC GGCATTTGGG AATTGTTGAT 
GCCTTCCAAC AGGGCAAGGC TGACTTGTCG GCAATGTCAG CGGAGAGAGA CCTGTGTCTG 
TCCAAGTTCG TGCACAAGAG TTTTGTGGAG GTGAATGAAG AAGGCACCGA GGCAGCGGCA 
GCGTCGAGCT GCTTTGTAGT TGCAGAGTGC TGCATGGAAT CTGGCCCCAG GTTCTGTGCT 
GACCACCCTT TCCTTTTCTT CATCAGGCAC AACAGAGCCA ACAGCATTCT GTTCTGTGGC 
AGGTTCTCAT CGCCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu59678
Clone ID Related Accession (Same CDS sequence) XM_017010943.1 , XM_017010942.1 , XM_011514678.2
Accession Version XM_011514678.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 978bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product serpin B9 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514678.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCACCAT GCCTGGCACT GTCTTTAAAC ACAGAGGAAG ACATTCATCG GGCTTTCCAG 
TCGCTTCTCA CTGAAGTGAA CAAGGCTGGC ACACAGTACC TGCTGAGAAC GGCCAACAGG 
CTCTTTGGAG AGAAAACTTG TCAGTTCCTC TCAACGTTTA AGGAATCCTG TCTTCAATTC 
TACCATGCTG AGCTGAAGGA GCTTTCCTTT ATCAGAGCTG CAGAAGAGTC CAGGAAACAC 
ATCAACACCT GGGTCTCAAA AAAGACCGAA GGTAAAATTG AAGAGTTGTT GCCGGGTAGC 
TCAATTGATG CAGAAACCAG GCTGGTTCTT GTCAATGCCA TCTACTTCAA AGGAAAGTGG 
AATGAACCGT TTGACGAAAC ATACACAAGG GAAATGCCCT TTAAAATAAA CCAGGAGGAG 
CAAAGGCCAG TGCAGATGAT GTATCAGGAG GCCACGTTTA AGCTCGCCCA CGTGGGCGAG 
GTGCGCGCGC AGCTGCTGGA GCTGCCCTAC GCCAGGAAGG AGCTGAGCCT GCTGGTGCTG 
CTGCCTGACG ACGGCGTGGA GCTCAGCACG GTGGAAAAAA GTCTCACTTT TGAGAAACTC 
ACAGCCTGGA CCAAGCCAGA CTGTATGAAG AGTACTGAGG TTGAAGTTCT CCTTCCAAAA 
TTTAAACTAC AAGAGGATTA TGACATGGAA TCTGTGCTTC GGCATTTGGG AATTGTTGAT 
GCCTTCCAAC AGGGCAAGGC TGACTTGTCG GCAATGTCAG CGGAGAGAGA CCTGTGTCTG 
TCCAAGTTCG TGCACAAGAG TTTTGTGGAG GTGAATGAAG AAGGCACCGA GGCAGCGGCA 
GCGTCGAGCT GCTTTGTAGT TGCAGAGTGC TGCATGGAAT CTGGCCCCAG GTTCTGTGCT 
GACCACCCTT TCCTTTTCTT CATCAGGCAC AACAGAGCCA ACAGCATTCT GTTCTGTGGC 
AGGTTCTCAT CGCCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011512980.1
CDS287..1264
Translation

Target ORF information:

RefSeq Version XM_011514678.2
Organism Homo sapiens(human)
Definition Homo sapiens serpin family B member 9 (SERPINB9), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011514678.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCACCAT GCCTGGCACT GTCTTTAAAC ACAGAGGAAG ACATTCATCG GGCTTTCCAG 
TCGCTTCTCA CTGAAGTGAA CAAGGCTGGC ACACAGTACC TGCTGAGAAC GGCCAACAGG 
CTCTTTGGAG AGAAAACTTG TCAGTTCCTC TCAACGTTTA AGGAATCCTG TCTTCAATTC 
TACCATGCTG AGCTGAAGGA GCTTTCCTTT ATCAGAGCTG CAGAAGAGTC CAGGAAACAC 
ATCAACACCT GGGTCTCAAA AAAGACCGAA GGTAAAATTG AAGAGTTGTT GCCGGGTAGC 
TCAATTGATG CAGAAACCAG GCTGGTTCTT GTCAATGCCA TCTACTTCAA AGGAAAGTGG 
AATGAACCGT TTGACGAAAC ATACACAAGG GAAATGCCCT TTAAAATAAA CCAGGAGGAG 
CAAAGGCCAG TGCAGATGAT GTATCAGGAG GCCACGTTTA AGCTCGCCCA CGTGGGCGAG 
GTGCGCGCGC AGCTGCTGGA GCTGCCCTAC GCCAGGAAGG AGCTGAGCCT GCTGGTGCTG 
CTGCCTGACG ACGGCGTGGA GCTCAGCACG GTGGAAAAAA GTCTCACTTT TGAGAAACTC 
ACAGCCTGGA CCAAGCCAGA CTGTATGAAG AGTACTGAGG TTGAAGTTCT CCTTCCAAAA 
TTTAAACTAC AAGAGGATTA TGACATGGAA TCTGTGCTTC GGCATTTGGG AATTGTTGAT 
GCCTTCCAAC AGGGCAAGGC TGACTTGTCG GCAATGTCAG CGGAGAGAGA CCTGTGTCTG 
TCCAAGTTCG TGCACAAGAG TTTTGTGGAG GTGAATGAAG AAGGCACCGA GGCAGCGGCA 
GCGTCGAGCT GCTTTGTAGT TGCAGAGTGC TGCATGGAAT CTGGCCCCAG GTTCTGTGCT 
GACCACCCTT TCCTTTTCTT CATCAGGCAC AACAGAGCCA ACAGCATTCT GTTCTGTGGC 
AGGTTCTCAT CGCCATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Leukemia31(11)2426-2434(2017 Nov)
Glavey SV,Naba A,Manier S,Clauser K,Tahri S,Park J,Reagan MR,Moschetta M,Mishima Y,Gambella M,Rocci A,Sacco A,O'Dwyer ME,Asara JM,Palumbo A,Roccaro AM,Hynes RO,Ghobrial IM


book

The analysis of estrogen receptor-? positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms.
International journal of oncology49(1)352-60(2016 Jul)
Lauricella M,Carlisi D,Giuliano M,Calvaruso G,Cernigliaro C,Vento R,D'Anneo A


book

Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors.
Cancer immunology, immunotherapy : CII65(5)575-85(2016 May)
van Kempen PM,Noorlag R,Swartz JE,Bovenschen N,Braunius WW,Vermeulen JF,Van Cann EM,Grolman W,Willems SM


book

Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease.
Oncotarget7(15)19265-71(2016 Apr)
van der Burgh R,Meeldijk J,Jongeneel L,Frenkel J,Bovenschen N,van Gijn M,Boes M


book

Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors.
PloS one11(3)e0151465(2016)
Vermeulen JF,van Hecke W,Spliet WG,Villacorta Hidalgo J,Fisch P,Broekhuizen R,Bovenschen N