Gene Symbol | ANKRD53 |
Entrez Gene ID | 79998 |
Full Name | ankyrin repeat domain 53 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » ANKRD53 cDNA ORF clone
gRNAs
Gene Symbol | ANKRD53 |
Entrez Gene ID | 79998 |
Full Name | ankyrin repeat domain 53 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_024933.3 | NP_079209.3 | ankyrin repeat domain-containing protein 53 isoform b |
NM_001369683.1 | NP_001356612.1 | ankyrin repeat domain-containing protein 53 isoform c |
XM_005264569.4 | XP_005264626.1 | ankyrin repeat domain-containing protein 53 isoform X1 |
NM_001115116.1 | NP_001108588.1 | ankyrin repeat domain-containing protein 53 isoform a |
XM_011533114.3 | XP_011531416.1 | ankyrin repeat domain-containing protein 53 isoform X2 |
NM_024933.4 | NP_079209.3 | ankyrin repeat domain-containing protein 53 isoform b |
XM_005264569.5 | XP_005264626.1 | ankyrin repeat domain-containing protein 53 isoform X1 |
XM_011533114.2 | XP_011531416.1 | ankyrin repeat domain-containing protein 53 isoform X2 |
NM_001115116.2 | NP_001108588.1 | ankyrin repeat domain-containing protein 53 isoform a |
Canis lupus familiaris (dog) | ANKRD53 | XP_005626255.1 |
Xenopus tropicalis (tropical clawed frog) | LOC101732970 | XP_004916485.1 |
ANKRD53 | XP_001101292.1 | |
Mus musculus (house mouse) | Ankrd53 | NP_083521.2 |
Homo sapiens (human) | ANKRD53 | NP_001108588.1 |
Bos taurus (cattle) | ANKRD53 | XP_002691275.1 |
Danio rerio (zebrafish) | LOC567792 | XP_696186.2 |
Pan troglodytes (chimpanzee) | ANKRD53 | XP_515534.2 |
ANKRD53 interacts with DDA3 and regulates chromosome integrity during mitosis.
Kim S, Jang CY
Biochemical and biophysical research communications470(3)484-491(2016 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Thus, ANKRD53 is recruited to the mitotic spindle by DDA3 and acts as a regulator of spindle dynamics and cytokinesis.
Title: ANKRD53 interacts with DDA3 and regulates chromosome integrity during mitosis.
The following ANKRD53 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ANKRD53 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu24297![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001115116.1 , NM_001115116.2 | |
Accession Version | NM_001115116.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC035234.1, AK093479.1 and AC007040.2. Transcript Variant: This variant (1) encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK093479.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001108588.1 |
CDS | 202..1794 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu24297![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001115116.1 , NM_001115116.2 | |
Accession Version | NM_001115116.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK093479.1 and AC007040.2. On Nov 24, 2018 this sequence version replaced NM_001115116.1. Transcript Variant: This variant (1) encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK093479.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000360589.4/ ENSP00000353796.3 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001108588.1 |
CDS | 17..1609 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu35612 | |
Clone ID Related Accession (Same CDS sequence) | NM_001369683.1 , XM_005264569.4 , XM_005264569.5 | |
Accession Version | NM_001369683.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-14 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC007040.2. On Apr 15, 2019 this sequence version replaced XM_005264569.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length. |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001356612.1 |
CDS | 202..1692 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu35612 | |
Clone ID Related Accession (Same CDS sequence) | NM_001369683.1 , XM_005264569.4 , XM_005264569.5 | |
Accession Version | XM_005264569.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005264569.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005264626.1 |
CDS | 1464..2954 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu35612 | |
Clone ID Related Accession (Same CDS sequence) | NM_001369683.1 , XM_005264569.4 , XM_005264569.5 | |
Accession Version | XM_005264569.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-03-25 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005264569.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005264626.1 |
CDS | 1464..2954 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu24296 | |
Clone ID Related Accession (Same CDS sequence) | NM_024933.3 , NM_024933.4 | |
Accession Version | NM_024933.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1032bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-23 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC035234.1, DB036445.1 and AC007040.2. On Mar 5, 2008 this sequence version replaced NM_024933.2. Transcript Variant: This variant (2) contains an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC035234.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_079209.3 |
CDS | 202..1233 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu24296 | |
Clone ID Related Accession (Same CDS sequence) | NM_024933.3 , NM_024933.4 | |
Accession Version | NM_024933.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1032bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-03 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC035234.1, DB036445.1 and AC007040.2. On May 31, 2019 this sequence version replaced NM_024933.3. Transcript Variant: This variant (2) contains an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC035234.1, SRR3476690.206139.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length. |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_079209.3 |
CDS | 17..1048 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu72469 | |
Clone ID Related Accession (Same CDS sequence) | XM_011533114.3 , XM_011533114.2 | |
Accession Version | XM_011533114.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011533114.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011531416.1 |
CDS | 38..1465 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu72469 | |
Clone ID Related Accession (Same CDS sequence) | XM_011533114.3 , XM_011533114.2 | |
Accession Version | XM_011533114.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | ankyrin repeat domain-containing protein 53 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011533114.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011531416.1 |
CDS | 38..1465 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCCG CGGGCAGCAC CGCTCGGCGG GCGGGCTCCG GAAGCTGGCA CTCAGAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ANKRD53 interacts with DDA3 and regulates chromosome integrity during mitosis. |