SMC3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SMC3
Entrez Gene ID	9126
Full Name	structural maintenance of chromosomes 3
Synonyms	BAM,BMH,CDLS3,CSPG6,HCAP,SMC3L1
General protein information	Preferred Names structural maintenance of chromosomes 3 Names structural maintenance of chromosomes protein 3 SMC protein 3 basement membrane-associated chondroitin proteoglycan chondroitin sulfate proteoglycan 6 (bamacan) chromosome-associated polypeptide
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q25.2
Summary	This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008].
Disorder MIM:	606062
Disorder Html:	Cornelia de Lange syndrome 3, 610759 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005445.4	NP_005436.1	structural maintenance of chromosomes protein 3
NM_005445.3	NP_005436.1	structural maintenance of chromosomes protein 3

Pathways from BioSystems

Homologies

	SMC3	XP_002805863.1
Mus musculus (house mouse)	Smc3	NP_031816.2
Rattus norvegicus (Norway rat)	Smc3	NP_113771.2
Canis lupus familiaris (dog)	SMC3	XP_851818.2
Eremothecium gossypii	AGOS_AAL182W	NP_982360.1
Homo sapiens (human)	SMC3	NP_005436.1
Pan troglodytes (chimpanzee)	SMC3	XP_508031.3
Bos taurus (cattle)	SMC3	NP_776720.1
Saccharomyces cerevisiae (baker's yeast)	SMC3	NP_012461.1
Gallus gallus (chicken)	SMC3	NP_989848.1
Drosophila melanogaster (fruit fly)	Cap	NP_523374.2
Caenorhabditis elegans (roundworm)	smc-3	NP_001255118.1
Schizosaccharomyces pombe (fission yeast)	psm3	NP_593260.1
Arabidopsis thaliana (thale cress)	TTN7	NP_180285.4
Oryza sativa (rice)	Os02g0133300	NP_001045803.1
Oryza sativa (rice)	Os02g0133400	NP_001172788.1
Xenopus tropicalis (tropical clawed frog)	smc3	XP_002939544.2
Danio rerio (zebrafish)	smc3	NP_999854.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006388	XP_316422.3
Kluyveromyces lactis	KLLA0A00286g	XP_451012.2
Magnaporthe oryzae (rice blast fungus)	MGG_04988	XP_003712488.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity.
Orgil O, Mor H, Matityahu A, Onn I
Nucleic acids research44(13)6309-17(2016 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We identified a large number of mutations in the CC region of both Smc1 and Smc3... we introduced them to the yeast Smc1 and Smc3 CC domains and characterized the effect of these mutant alleles on cohesin's function. We identified a missense mutation in the region of the kink domain of Smc3, which was previously identified in kidney carcinoma
Title: Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity.

Results show that SMC3 is upregulated in asthma patients and suggest that it may play an important role in atopic asthma development, especially in asthma epithelial-mesenchymal transition.
Title: SMC3 may play an important role in atopic asthma development.

Data show that histone deacetylase 8 (HDAC8) inhibition led to accumulation of acetylated-SMC3 protein but had no influence on the transcription of estrogen-responsive genes.
Title: HDAC8 Inhibition Blocks SMC3 Deacetylation and Delays Cell Cycle Progression without Affecting Cohesin-dependent Transcription in MCF7 Cancer Cells.

De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes
Title: De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes.

cohesin's proposed DNA exit gate is formed by interactions between Scc1 and the coiled-coil region of Smc3.
Title: Characterization of a DNA exit gate in the human cohesin ring.

The following SMC3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SMC3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22171	NM_005445.4 Latest version!	Homo sapiens structural maintenance of chromosomes 3 (SMC3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	Quote Price
View Old Accession Versions >>
OHu22171	NM_005445.3	Homo sapiens structural maintenance of chromosomes 3 (SMC3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	Quote Price
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SMC3 ( NM_005445.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005436.1 Homo sapiens structural maintenance of chromosomes 3 (SMC3), mRNA.

Price & Availability↑

CloneID	OHu22171
Clone ID Related Accession (Same CDS sequence)	NM_005445.4 , NM_005445.3
Accession Version	NM_005445.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	structural maintenance of chromosomes protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CA439554.1, AF020043.1 and AL359260.20. On Dec 4, 2019 this sequence version replaced NM_005445.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289771.1, SRR1660807.243350.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTACATAA AGCAGGTGAT TATCCAGGGT TTTCGAAGTT ACAGAGATCA AACAATTGTA 
GATCCCTTCA GTTCAAAACA TAATGTGATT GTGGGCAGAA ATGGATCTGG AAAAAGTAAC 
TTTTTTTATG CAATTCAGTT TGTTCTCAGT GATGAGTTTA GTCATCTTCG TCCAGAACAG 
CGGTTGGCTT TATTGCATGA AGGTACTGGT CCTCGTGTTA TTTCTGCTTT TGTGGAGATT 
ATTTTTGATA ATTCAGACAA CCGGTTACCA ATCGATAAAG AGGAAGTTTC ACTTCGAAGA 
GTTATTGGTG CCAAAAAGGA TCAGTATTTC TTAGACAAGA AGATGGTCAC GAAAAATGAT 
GTGATGAACC TCCTTGAAAG CGCTGGTTTT TCTCGAAGCA ATCCTTATTA TATTGTTAAA 
CAAGGAAAGA TCAACCAGAT GGCAACAGCA CCAGATTCTC AGAGATTAAA GCTATTAAGA 
GAAGTAGCTG GTACTAGAGT GTATGACGAA CGAAAGGAAG AAAGCATCTC CTTAATGAAA 
GAAACAGAGG GCAAACGGGA AAAAATCAAT GAGTTGTTAA AATACATTGA AGAGAGATTA 
CATACTCTAG AGGAAGAAAA GGAAGAACTA GCTCAGTATC AGAAGTGGGA TAAAATGAGA 
CGAGCCCTGG AATATACCAT TTACAATCAG GAACTTAACG AGACTCGTGC CAAACTTGAT 
GAGCTTTCTG CTAAGCGAGA GACTAGTGGA GAAAAATCCA GACAATTAAG AGATGCTCAG 
CAGGATGCAA GAGATAAAAT GGAGGATATC GAACGCCAAG TTAGAGAATT GAAAACAAAA 
ATTTCAGCTA TGAAAGAAGA AAAAGAACAG CTTAGTGCTG AAAGACAAGA GCAGATTAAG 
CAGAGGACTA AGTTGGAGCT TAAAGCCAAG GATTTACAAG ATGAACTAGC AGGCAATAGT 
GAACAAAGGA AACGTTTATT AAAAGAGAGG CAGAAGCTGC TTGAAAAAAT AGAAGAAAAG 
CAGAAAGAAC TGGCAGAAAC AGAACCCAAA TTCAACAGTG TGAAAGAGAA AGAAGAACGA 
GGAATTGCTA GATTGGCTCA AGCTACCCAG GAAAGAACGG ATCTTTATGC AAAGCAGGGT 
CGAGGAAGCC AGTTTACATC AAAAGAAGAA AGGGATAAGT GGATTAAAAA GGAACTCAAG 
TCTTTAGATC AGGCTATTAA TGACAAGAAA AGACAGATTG CTGCTATACA TAAGGATTTG 
GAAGACACTG AAGCAAATAA AGAGAAAAAT CTGGAGCAGT ATAATAAACT GGACCAGGAT 
CTTAATGAAG TCAAAGCTCG AGTAGAAGAA CTGGACAGAA AATATTACGA AGTAAAAAAT 
AAGAAAGATG AACTACAAAG TGAAAGAAAC TACTTGTGGA GAGAAGAGAA TGCAGAACAG 
CAAGCACTTG CTGCTAAAAG AGAAGATCTT GAAAAGAAGC AACAACTTCT TAGAGCAGCA 
ACAGGAAAGG CCATTTTAAA TGGAATAGAC AGCATAAACA AAGTGCTAGA CCACTTCCGT 
CGAAAAGGAA TAAACCAGCA TGTTCAAAAT GGCTATCATG GTATTGTAAT GAATAACTTT 
GAATGTGAAC CAGCTTTCTA CACATGCGTG GAAGTCACTG CTGGAAACAG GTTATTTTAT 
CACATTGTTG ATTCAGATGA AGTCAGCACG AAGATTTTAA TGGAGTTTAA TAAAATGAAT 
CTTCCTGGAG AGGTTACTTT TCTGCCTCTT AACAAGTTAG ATGTCAGGGA TACAGCCTAT 
CCTGAAACCA ATGATGCTAT TCCTATGATC AGCAAACTGA GGTACAATCC CAGATTTGAC 
AAAGCTTTCA AACATGTGTT TGGAAAGACT CTTATTTGTC GTAGCATGGA AGTTTCAACC 
CAGCTGGCCC GTGCTTTCAC TATGGACTGT ATTACTTTGG AAGGTGACCA AGTCAGCCAT 
CGGGGTGCTC TAACTGGGGG TTATTATGAC ACAAGGAAGT CTCGACTTGA ATTGCAAAAA 
GATGTTAGAA AAGCAGAAGA AGAACTAGGT GAACTTGAAG CAAAGCTCAA TGAAAACCTG 
CGCAGAAATA TTGAAAGGAT TAATAATGAA ATTGATCAGT TGATGAACCA AATGCAACAG 
ATCGAGACCC AGCAAAGGAA ATTTAAAGCA TCTAGAGATA GCATATTATC AGAAATGAAG 
ATGCTAAAAG AGAAGAGGCA GCAGTCAGAG AAAACCTTCA TGCCTAAGCA ACGTAGCTTA 
CAGAGTTTGG AGGCAAGCTT GCATGCTATG GAGTCTACCA GAGAGTCATT GAAAGCAGAA 
CTGGGAACTG ATTTGCTTTC TCAACTGAGT TTGGAAGATC AGAAGAGAGT AGATGCACTG 
AATGATGAGA TTCGTCAACT TCAGCAGGAA AACAGACAGT TGCTAAATGA AAGAATTAAA 
TTAGAAGGTA TTATTACTCG AGTAGAGACT TATCTCAATG AGAATCTGAG AAAACGCTTG 
GACCAAGTAG AACAGGAACT TAATGAGCTG AGAGAGACAG AAGGGGGTAC TGTTCTCACA 
GCCACAACAT CAGAACTTGA AGCCATCAAT AAAAGAGTAA AAGACACTAT GGCACGATCA 
GAAGATTTGG ACAATTCCAT TGATAAAACA GAAGCTGGAA TTAAGGAGCT TCAGAAGAGT 
ATGGAGCGCT GGAAAAATAT GGAAAAAGAA CATATGGATG CTATAAATCA TGATACTAAA 
GAACTGGAAA AGATGACAAA TCGGCAAGGC ATGCTATTGA AGAAGAAAGA AGAGTGTATG 
AAGAAAATTC GAGAACTTGG ATCACTTCCC CAGGAAGCAT TTGAAAAGTA CCAGACACTG 
AGCCTCAAAC AGTTGTTTCG AAAACTTGAG CAGTGCAACA CAGAATTAAA GAAGTACAGC 
CATGTTAACA AAAAGGCTTT GGATCAGTTT GTAAATTTCT CCGAGCAGAA AGAAAAGTTA 
ATAAAGCGTC AAGAAGAGTT AGATAGGGGT TACAAATCAA TCATGGAACT GATGAATGTA 
CTTGAACTTC GGAAATATGA AGCTATTCAG TTAACTTTCA AACAGGTATC TAAGAACTTC 
AGTGAAGTAT TCCAGAAGTT AGTACCTGGT GGCAAAGCTA CTTTGGTGAT GAAGAAAGGA 
GATGTGGAGG GCAGTCAGTC TCAAGATGAA GGAGAAGGGA GTGGTGAGAG TGAGAGGGGT 
TCTGGCTCAC AAAGCAGTGT CCCATCAGTT GACCAGTTTA CTGGAGTTGG AATTAGGGTG 
TCATTTACAG GAAAACAAGG TGAAATGAGA GAAATGCAAC AGCTTTCAGG TGGACAGAAA 
TCCTTGGTAG CCCTTGCTCT GATTTTTGCC ATTCAGAAAT GTGACCCGGC TCCATTTTAC 
TTGTTTGATG AAATTGACCA GGCTCTGGAT GCTCAGCACA GAAAGGCTGT GTCAGATATG 
ATTATGGAAC TTGCTGTACA TGCTCAGTTT ATTACAACTA CTTTTAGGCC TGAACTGCTT 
GAGTCAGCTG ACAAATTCTA TGGTGTAAAG TTCAGAAATA AGGTTAGTCA TATTGATGTG 
ATCACAGCAG AGATGGCCAA AGACTTTGTA GAAGATGATA CCACACATGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005436.1
CDS	123..3776
Translation	MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLSDEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRRVIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKREDLEKKQQLLRAATGKAILNGIDSINKVLDHFRRKGINQHVQNGYHGIVMNNFECEPAFYTCVEVTAGNRLFYHIVDSDEVSTKILMEFNKMNLPGEVTFLPLNKLDVRDTAYPETNDAIPMISKLRYNPRFDKAFKHVFGKTLICRSMEVSTQLARAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETEGGTVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEELDRGYKSIMELMNVLELRKYEAIQLTFKQVSKNFSEVFQKLVPGGKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVPSVDQFTGVGIRVSFTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIMELAVHAQFITTTFRPELLESADKFYGVKFRNKVSHIDVITAEMAKDFVEDDTTHG

Target ORF information:

RefSeq Version	NM_005445.4
Organism	Homo sapiens(human)
Definition	Homo sapiens structural maintenance of chromosomes 3 (SMC3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005445.4

ORF Insert Sequence:

ATGTACATAA AGCAGGTGAT TATCCAGGGT TTTCGAAGTT ACAGAGATCA AACAATTGTA 
GATCCCTTCA GTTCAAAACA TAATGTGATT GTGGGCAGAA ATGGATCTGG AAAAAGTAAC 
TTTTTTTATG CAATTCAGTT TGTTCTCAGT GATGAGTTTA GTCATCTTCG TCCAGAACAG 
CGGTTGGCTT TATTGCATGA AGGTACTGGT CCTCGTGTTA TTTCTGCTTT TGTGGAGATT 
ATTTTTGATA ATTCAGACAA CCGGTTACCA ATCGATAAAG AGGAAGTTTC ACTTCGAAGA 
GTTATTGGTG CCAAAAAGGA TCAGTATTTC TTAGACAAGA AGATGGTCAC GAAAAATGAT 
GTGATGAACC TCCTTGAAAG CGCTGGTTTT TCTCGAAGCA ATCCTTATTA TATTGTTAAA 
CAAGGAAAGA TCAACCAGAT GGCAACAGCA CCAGATTCTC AGAGATTAAA GCTATTAAGA 
GAAGTAGCTG GTACTAGAGT GTATGACGAA CGAAAGGAAG AAAGCATCTC CTTAATGAAA 
GAAACAGAGG GCAAACGGGA AAAAATCAAT GAGTTGTTAA AATACATTGA AGAGAGATTA 
CATACTCTAG AGGAAGAAAA GGAAGAACTA GCTCAGTATC AGAAGTGGGA TAAAATGAGA 
CGAGCCCTGG AATATACCAT TTACAATCAG GAACTTAACG AGACTCGTGC CAAACTTGAT 
GAGCTTTCTG CTAAGCGAGA GACTAGTGGA GAAAAATCCA GACAATTAAG AGATGCTCAG 
CAGGATGCAA GAGATAAAAT GGAGGATATC GAACGCCAAG TTAGAGAATT GAAAACAAAA 
ATTTCAGCTA TGAAAGAAGA AAAAGAACAG CTTAGTGCTG AAAGACAAGA GCAGATTAAG 
CAGAGGACTA AGTTGGAGCT TAAAGCCAAG GATTTACAAG ATGAACTAGC AGGCAATAGT 
GAACAAAGGA AACGTTTATT AAAAGAGAGG CAGAAGCTGC TTGAAAAAAT AGAAGAAAAG 
CAGAAAGAAC TGGCAGAAAC AGAACCCAAA TTCAACAGTG TGAAAGAGAA AGAAGAACGA 
GGAATTGCTA GATTGGCTCA AGCTACCCAG GAAAGAACGG ATCTTTATGC AAAGCAGGGT 
CGAGGAAGCC AGTTTACATC AAAAGAAGAA AGGGATAAGT GGATTAAAAA GGAACTCAAG 
TCTTTAGATC AGGCTATTAA TGACAAGAAA AGACAGATTG CTGCTATACA TAAGGATTTG 
GAAGACACTG AAGCAAATAA AGAGAAAAAT CTGGAGCAGT ATAATAAACT GGACCAGGAT 
CTTAATGAAG TCAAAGCTCG AGTAGAAGAA CTGGACAGAA AATATTACGA AGTAAAAAAT 
AAGAAAGATG AACTACAAAG TGAAAGAAAC TACTTGTGGA GAGAAGAGAA TGCAGAACAG 
CAAGCACTTG CTGCTAAAAG AGAAGATCTT GAAAAGAAGC AACAACTTCT TAGAGCAGCA 
ACAGGAAAGG CCATTTTAAA TGGAATAGAC AGCATAAACA AAGTGCTAGA CCACTTCCGT 
CGAAAAGGAA TAAACCAGCA TGTTCAAAAT GGCTATCATG GTATTGTAAT GAATAACTTT 
GAATGTGAAC CAGCTTTCTA CACATGCGTG GAAGTCACTG CTGGAAACAG GTTATTTTAT 
CACATTGTTG ATTCAGATGA AGTCAGCACG AAGATTTTAA TGGAGTTTAA TAAAATGAAT 
CTTCCTGGAG AGGTTACTTT TCTGCCTCTT AACAAGTTAG ATGTCAGGGA TACAGCCTAT 
CCTGAAACCA ATGATGCTAT TCCTATGATC AGCAAACTGA GGTACAATCC CAGATTTGAC 
AAAGCTTTCA AACATGTGTT TGGAAAGACT CTTATTTGTC GTAGCATGGA AGTTTCAACC 
CAGCTGGCCC GTGCTTTCAC TATGGACTGT ATTACTTTGG AAGGTGACCA AGTCAGCCAT 
CGGGGTGCTC TAACTGGGGG TTATTATGAC ACAAGGAAGT CTCGACTTGA ATTGCAAAAA 
GATGTTAGAA AAGCAGAAGA AGAACTAGGT GAACTTGAAG CAAAGCTCAA TGAAAACCTG 
CGCAGAAATA TTGAAAGGAT TAATAATGAA ATTGATCAGT TGATGAACCA AATGCAACAG 
ATCGAGACCC AGCAAAGGAA ATTTAAAGCA TCTAGAGATA GCATATTATC AGAAATGAAG 
ATGCTAAAAG AGAAGAGGCA GCAGTCAGAG AAAACCTTCA TGCCTAAGCA ACGTAGCTTA 
CAGAGTTTGG AGGCAAGCTT GCATGCTATG GAGTCTACCA GAGAGTCATT GAAAGCAGAA 
CTGGGAACTG ATTTGCTTTC TCAACTGAGT TTGGAAGATC AGAAGAGAGT AGATGCACTG 
AATGATGAGA TTCGTCAACT TCAGCAGGAA AACAGACAGT TGCTAAATGA AAGAATTAAA 
TTAGAAGGTA TTATTACTCG AGTAGAGACT TATCTCAATG AGAATCTGAG AAAACGCTTG 
GACCAAGTAG AACAGGAACT TAATGAGCTG AGAGAGACAG AAGGGGGTAC TGTTCTCACA 
GCCACAACAT CAGAACTTGA AGCCATCAAT AAAAGAGTAA AAGACACTAT GGCACGATCA 
GAAGATTTGG ACAATTCCAT TGATAAAACA GAAGCTGGAA TTAAGGAGCT TCAGAAGAGT 
ATGGAGCGCT GGAAAAATAT GGAAAAAGAA CATATGGATG CTATAAATCA TGATACTAAA 
GAACTGGAAA AGATGACAAA TCGGCAAGGC ATGCTATTGA AGAAGAAAGA AGAGTGTATG 
AAGAAAATTC GAGAACTTGG ATCACTTCCC CAGGAAGCAT TTGAAAAGTA CCAGACACTG 
AGCCTCAAAC AGTTGTTTCG AAAACTTGAG CAGTGCAACA CAGAATTAAA GAAGTACAGC 
CATGTTAACA AAAAGGCTTT GGATCAGTTT GTAAATTTCT CCGAGCAGAA AGAAAAGTTA 
ATAAAGCGTC AAGAAGAGTT AGATAGGGGT TACAAATCAA TCATGGAACT GATGAATGTA 
CTTGAACTTC GGAAATATGA AGCTATTCAG TTAACTTTCA AACAGGTATC TAAGAACTTC 
AGTGAAGTAT TCCAGAAGTT AGTACCTGGT GGCAAAGCTA CTTTGGTGAT GAAGAAAGGA 
GATGTGGAGG GCAGTCAGTC TCAAGATGAA GGAGAAGGGA GTGGTGAGAG TGAGAGGGGT 
TCTGGCTCAC AAAGCAGTGT CCCATCAGTT GACCAGTTTA CTGGAGTTGG AATTAGGGTG 
TCATTTACAG GAAAACAAGG TGAAATGAGA GAAATGCAAC AGCTTTCAGG TGGACAGAAA 
TCCTTGGTAG CCCTTGCTCT GATTTTTGCC ATTCAGAAAT GTGACCCGGC TCCATTTTAC 
TTGTTTGATG AAATTGACCA GGCTCTGGAT GCTCAGCACA GAAAGGCTGT GTCAGATATG 
ATTATGGAAC TTGCTGTACA TGCTCAGTTT ATTACAACTA CTTTTAGGCC TGAACTGCTT 
GAGTCAGCTG ACAAATTCTA TGGTGTAAAG TTCAGAAATA AGGTTAGTCA TATTGATGTG 
ATCACAGCAG AGATGGCCAA AGACTTTGTA GAAGATGATA CCACACATGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMC3 ( NM_005445.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005436.1 Homo sapiens structural maintenance of chromosomes 3 (SMC3), mRNA.

Price & Availability↑

CloneID	OHu22171
Clone ID Related Accession (Same CDS sequence)	NM_005445.4 , NM_005445.3
Accession Version	NM_005445.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	structural maintenance of chromosomes protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CA439554.1, AF020043.1 and AL359260.20. This sequence is a reference standard in the RefSeqGene project. On May 5, 2005 this sequence version replaced NM_005445.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF020043.1, SRR1803611.5954.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTACATAA AGCAGGTGAT TATCCAGGGT TTTCGAAGTT ACAGAGATCA AACAATTGTA 
GATCCCTTCA GTTCAAAACA TAATGTGATT GTGGGCAGAA ATGGATCTGG AAAAAGTAAC 
TTTTTTTATG CAATTCAGTT TGTTCTCAGT GATGAGTTTA GTCATCTTCG TCCAGAACAG 
CGGTTGGCTT TATTGCATGA AGGTACTGGT CCTCGTGTTA TTTCTGCTTT TGTGGAGATT 
ATTTTTGATA ATTCAGACAA CCGGTTACCA ATCGATAAAG AGGAAGTTTC ACTTCGAAGA 
GTTATTGGTG CCAAAAAGGA TCAGTATTTC TTAGACAAGA AGATGGTCAC GAAAAATGAT 
GTGATGAACC TCCTTGAAAG CGCTGGTTTT TCTCGAAGCA ATCCTTATTA TATTGTTAAA 
CAAGGAAAGA TCAACCAGAT GGCAACAGCA CCAGATTCTC AGAGATTAAA GCTATTAAGA 
GAAGTAGCTG GTACTAGAGT GTATGACGAA CGAAAGGAAG AAAGCATCTC CTTAATGAAA 
GAAACAGAGG GCAAACGGGA AAAAATCAAT GAGTTGTTAA AATACATTGA AGAGAGATTA 
CATACTCTAG AGGAAGAAAA GGAAGAACTA GCTCAGTATC AGAAGTGGGA TAAAATGAGA 
CGAGCCCTGG AATATACCAT TTACAATCAG GAACTTAACG AGACTCGTGC CAAACTTGAT 
GAGCTTTCTG CTAAGCGAGA GACTAGTGGA GAAAAATCCA GACAATTAAG AGATGCTCAG 
CAGGATGCAA GAGATAAAAT GGAGGATATC GAACGCCAAG TTAGAGAATT GAAAACAAAA 
ATTTCAGCTA TGAAAGAAGA AAAAGAACAG CTTAGTGCTG AAAGACAAGA GCAGATTAAG 
CAGAGGACTA AGTTGGAGCT TAAAGCCAAG GATTTACAAG ATGAACTAGC AGGCAATAGT 
GAACAAAGGA AACGTTTATT AAAAGAGAGG CAGAAGCTGC TTGAAAAAAT AGAAGAAAAG 
CAGAAAGAAC TGGCAGAAAC AGAACCCAAA TTCAACAGTG TGAAAGAGAA AGAAGAACGA 
GGAATTGCTA GATTGGCTCA AGCTACCCAG GAAAGAACGG ATCTTTATGC AAAGCAGGGT 
CGAGGAAGCC AGTTTACATC AAAAGAAGAA AGGGATAAGT GGATTAAAAA GGAACTCAAG 
TCTTTAGATC AGGCTATTAA TGACAAGAAA AGACAGATTG CTGCTATACA TAAGGATTTG 
GAAGACACTG AAGCAAATAA AGAGAAAAAT CTGGAGCAGT ATAATAAACT GGACCAGGAT 
CTTAATGAAG TCAAAGCTCG AGTAGAAGAA CTGGACAGAA AATATTACGA AGTAAAAAAT 
AAGAAAGATG AACTACAAAG TGAAAGAAAC TACTTGTGGA GAGAAGAGAA TGCAGAACAG 
CAAGCACTTG CTGCTAAAAG AGAAGATCTT GAAAAGAAGC AACAACTTCT TAGAGCAGCA 
ACAGGAAAGG CCATTTTAAA TGGAATAGAC AGCATAAACA AAGTGCTAGA CCACTTCCGT 
CGAAAAGGAA TAAACCAGCA TGTTCAAAAT GGCTATCATG GTATTGTAAT GAATAACTTT 
GAATGTGAAC CAGCTTTCTA CACATGCGTG GAAGTCACTG CTGGAAACAG GTTATTTTAT 
CACATTGTTG ATTCAGATGA AGTCAGCACG AAGATTTTAA TGGAGTTTAA TAAAATGAAT 
CTTCCTGGAG AGGTTACTTT TCTGCCTCTT AACAAGTTAG ATGTCAGGGA TACAGCCTAT 
CCTGAAACCA ATGATGCTAT TCCTATGATC AGCAAACTGA GGTACAATCC CAGATTTGAC 
AAAGCTTTCA AACATGTGTT TGGAAAGACT CTTATTTGTC GTAGCATGGA AGTTTCAACC 
CAGCTGGCCC GTGCTTTCAC TATGGACTGT ATTACTTTGG AAGGTGACCA AGTCAGCCAT 
CGGGGTGCTC TAACTGGGGG TTATTATGAC ACAAGGAAGT CTCGACTTGA ATTGCAAAAA 
GATGTTAGAA AAGCAGAAGA AGAACTAGGT GAACTTGAAG CAAAGCTCAA TGAAAACCTG 
CGCAGAAATA TTGAAAGGAT TAATAATGAA ATTGATCAGT TGATGAACCA AATGCAACAG 
ATCGAGACCC AGCAAAGGAA ATTTAAAGCA TCTAGAGATA GCATATTATC AGAAATGAAG 
ATGCTAAAAG AGAAGAGGCA GCAGTCAGAG AAAACCTTCA TGCCTAAGCA ACGTAGCTTA 
CAGAGTTTGG AGGCAAGCTT GCATGCTATG GAGTCTACCA GAGAGTCATT GAAAGCAGAA 
CTGGGAACTG ATTTGCTTTC TCAACTGAGT TTGGAAGATC AGAAGAGAGT AGATGCACTG 
AATGATGAGA TTCGTCAACT TCAGCAGGAA AACAGACAGT TGCTAAATGA AAGAATTAAA 
TTAGAAGGTA TTATTACTCG AGTAGAGACT TATCTCAATG AGAATCTGAG AAAACGCTTG 
GACCAAGTAG AACAGGAACT TAATGAGCTG AGAGAGACAG AAGGGGGTAC TGTTCTCACA 
GCCACAACAT CAGAACTTGA AGCCATCAAT AAAAGAGTAA AAGACACTAT GGCACGATCA 
GAAGATTTGG ACAATTCCAT TGATAAAACA GAAGCTGGAA TTAAGGAGCT TCAGAAGAGT 
ATGGAGCGCT GGAAAAATAT GGAAAAAGAA CATATGGATG CTATAAATCA TGATACTAAA 
GAACTGGAAA AGATGACAAA TCGGCAAGGC ATGCTATTGA AGAAGAAAGA AGAGTGTATG 
AAGAAAATTC GAGAACTTGG ATCACTTCCC CAGGAAGCAT TTGAAAAGTA CCAGACACTG 
AGCCTCAAAC AGTTGTTTCG AAAACTTGAG CAGTGCAACA CAGAATTAAA GAAGTACAGC 
CATGTTAACA AAAAGGCTTT GGATCAGTTT GTAAATTTCT CCGAGCAGAA AGAAAAGTTA 
ATAAAGCGTC AAGAAGAGTT AGATAGGGGT TACAAATCAA TCATGGAACT GATGAATGTA 
CTTGAACTTC GGAAATATGA AGCTATTCAG TTAACTTTCA AACAGGTATC TAAGAACTTC 
AGTGAAGTAT TCCAGAAGTT AGTACCTGGT GGCAAAGCTA CTTTGGTGAT GAAGAAAGGA 
GATGTGGAGG GCAGTCAGTC TCAAGATGAA GGAGAAGGGA GTGGTGAGAG TGAGAGGGGT 
TCTGGCTCAC AAAGCAGTGT CCCATCAGTT GACCAGTTTA CTGGAGTTGG AATTAGGGTG 
TCATTTACAG GAAAACAAGG TGAAATGAGA GAAATGCAAC AGCTTTCAGG TGGACAGAAA 
TCCTTGGTAG CCCTTGCTCT GATTTTTGCC ATTCAGAAAT GTGACCCGGC TCCATTTTAC 
TTGTTTGATG AAATTGACCA GGCTCTGGAT GCTCAGCACA GAAAGGCTGT GTCAGATATG 
ATTATGGAAC TTGCTGTACA TGCTCAGTTT ATTACAACTA CTTTTAGGCC TGAACTGCTT 
GAGTCAGCTG ACAAATTCTA TGGTGTAAAG TTCAGAAATA AGGTTAGTCA TATTGATGTG 
ATCACAGCAG AGATGGCCAA AGACTTTGTA GAAGATGATA CCACACATGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005436.1
CDS	127..3780
Translation	MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLSDEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRRVIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKREDLEKKQQLLRAATGKAILNGIDSINKVLDHFRRKGINQHVQNGYHGIVMNNFECEPAFYTCVEVTAGNRLFYHIVDSDEVSTKILMEFNKMNLPGEVTFLPLNKLDVRDTAYPETNDAIPMISKLRYNPRFDKAFKHVFGKTLICRSMEVSTQLARAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETEGGTVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEELDRGYKSIMELMNVLELRKYEAIQLTFKQVSKNFSEVFQKLVPGGKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVPSVDQFTGVGIRVSFTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIMELAVHAQFITTTFRPELLESADKFYGVKFRNKVSHIDVITAEMAKDFVEDDTTHG

Target ORF information:

RefSeq Version	NM_005445.3
Organism	Homo sapiens(human)
Definition	Homo sapiens structural maintenance of chromosomes 3 (SMC3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005445.3

ORF Insert Sequence:

ATGTACATAA AGCAGGTGAT TATCCAGGGT TTTCGAAGTT ACAGAGATCA AACAATTGTA 
GATCCCTTCA GTTCAAAACA TAATGTGATT GTGGGCAGAA ATGGATCTGG AAAAAGTAAC 
TTTTTTTATG CAATTCAGTT TGTTCTCAGT GATGAGTTTA GTCATCTTCG TCCAGAACAG 
CGGTTGGCTT TATTGCATGA AGGTACTGGT CCTCGTGTTA TTTCTGCTTT TGTGGAGATT 
ATTTTTGATA ATTCAGACAA CCGGTTACCA ATCGATAAAG AGGAAGTTTC ACTTCGAAGA 
GTTATTGGTG CCAAAAAGGA TCAGTATTTC TTAGACAAGA AGATGGTCAC GAAAAATGAT 
GTGATGAACC TCCTTGAAAG CGCTGGTTTT TCTCGAAGCA ATCCTTATTA TATTGTTAAA 
CAAGGAAAGA TCAACCAGAT GGCAACAGCA CCAGATTCTC AGAGATTAAA GCTATTAAGA 
GAAGTAGCTG GTACTAGAGT GTATGACGAA CGAAAGGAAG AAAGCATCTC CTTAATGAAA 
GAAACAGAGG GCAAACGGGA AAAAATCAAT GAGTTGTTAA AATACATTGA AGAGAGATTA 
CATACTCTAG AGGAAGAAAA GGAAGAACTA GCTCAGTATC AGAAGTGGGA TAAAATGAGA 
CGAGCCCTGG AATATACCAT TTACAATCAG GAACTTAACG AGACTCGTGC CAAACTTGAT 
GAGCTTTCTG CTAAGCGAGA GACTAGTGGA GAAAAATCCA GACAATTAAG AGATGCTCAG 
CAGGATGCAA GAGATAAAAT GGAGGATATC GAACGCCAAG TTAGAGAATT GAAAACAAAA 
ATTTCAGCTA TGAAAGAAGA AAAAGAACAG CTTAGTGCTG AAAGACAAGA GCAGATTAAG 
CAGAGGACTA AGTTGGAGCT TAAAGCCAAG GATTTACAAG ATGAACTAGC AGGCAATAGT 
GAACAAAGGA AACGTTTATT AAAAGAGAGG CAGAAGCTGC TTGAAAAAAT AGAAGAAAAG 
CAGAAAGAAC TGGCAGAAAC AGAACCCAAA TTCAACAGTG TGAAAGAGAA AGAAGAACGA 
GGAATTGCTA GATTGGCTCA AGCTACCCAG GAAAGAACGG ATCTTTATGC AAAGCAGGGT 
CGAGGAAGCC AGTTTACATC AAAAGAAGAA AGGGATAAGT GGATTAAAAA GGAACTCAAG 
TCTTTAGATC AGGCTATTAA TGACAAGAAA AGACAGATTG CTGCTATACA TAAGGATTTG 
GAAGACACTG AAGCAAATAA AGAGAAAAAT CTGGAGCAGT ATAATAAACT GGACCAGGAT 
CTTAATGAAG TCAAAGCTCG AGTAGAAGAA CTGGACAGAA AATATTACGA AGTAAAAAAT 
AAGAAAGATG AACTACAAAG TGAAAGAAAC TACTTGTGGA GAGAAGAGAA TGCAGAACAG 
CAAGCACTTG CTGCTAAAAG AGAAGATCTT GAAAAGAAGC AACAACTTCT TAGAGCAGCA 
ACAGGAAAGG CCATTTTAAA TGGAATAGAC AGCATAAACA AAGTGCTAGA CCACTTCCGT 
CGAAAAGGAA TAAACCAGCA TGTTCAAAAT GGCTATCATG GTATTGTAAT GAATAACTTT 
GAATGTGAAC CAGCTTTCTA CACATGCGTG GAAGTCACTG CTGGAAACAG GTTATTTTAT 
CACATTGTTG ATTCAGATGA AGTCAGCACG AAGATTTTAA TGGAGTTTAA TAAAATGAAT 
CTTCCTGGAG AGGTTACTTT TCTGCCTCTT AACAAGTTAG ATGTCAGGGA TACAGCCTAT 
CCTGAAACCA ATGATGCTAT TCCTATGATC AGCAAACTGA GGTACAATCC CAGATTTGAC 
AAAGCTTTCA AACATGTGTT TGGAAAGACT CTTATTTGTC GTAGCATGGA AGTTTCAACC 
CAGCTGGCCC GTGCTTTCAC TATGGACTGT ATTACTTTGG AAGGTGACCA AGTCAGCCAT 
CGGGGTGCTC TAACTGGGGG TTATTATGAC ACAAGGAAGT CTCGACTTGA ATTGCAAAAA 
GATGTTAGAA AAGCAGAAGA AGAACTAGGT GAACTTGAAG CAAAGCTCAA TGAAAACCTG 
CGCAGAAATA TTGAAAGGAT TAATAATGAA ATTGATCAGT TGATGAACCA AATGCAACAG 
ATCGAGACCC AGCAAAGGAA ATTTAAAGCA TCTAGAGATA GCATATTATC AGAAATGAAG 
ATGCTAAAAG AGAAGAGGCA GCAGTCAGAG AAAACCTTCA TGCCTAAGCA ACGTAGCTTA 
CAGAGTTTGG AGGCAAGCTT GCATGCTATG GAGTCTACCA GAGAGTCATT GAAAGCAGAA 
CTGGGAACTG ATTTGCTTTC TCAACTGAGT TTGGAAGATC AGAAGAGAGT AGATGCACTG 
AATGATGAGA TTCGTCAACT TCAGCAGGAA AACAGACAGT TGCTAAATGA AAGAATTAAA 
TTAGAAGGTA TTATTACTCG AGTAGAGACT TATCTCAATG AGAATCTGAG AAAACGCTTG 
GACCAAGTAG AACAGGAACT TAATGAGCTG AGAGAGACAG AAGGGGGTAC TGTTCTCACA 
GCCACAACAT CAGAACTTGA AGCCATCAAT AAAAGAGTAA AAGACACTAT GGCACGATCA 
GAAGATTTGG ACAATTCCAT TGATAAAACA GAAGCTGGAA TTAAGGAGCT TCAGAAGAGT 
ATGGAGCGCT GGAAAAATAT GGAAAAAGAA CATATGGATG CTATAAATCA TGATACTAAA 
GAACTGGAAA AGATGACAAA TCGGCAAGGC ATGCTATTGA AGAAGAAAGA AGAGTGTATG 
AAGAAAATTC GAGAACTTGG ATCACTTCCC CAGGAAGCAT TTGAAAAGTA CCAGACACTG 
AGCCTCAAAC AGTTGTTTCG AAAACTTGAG CAGTGCAACA CAGAATTAAA GAAGTACAGC 
CATGTTAACA AAAAGGCTTT GGATCAGTTT GTAAATTTCT CCGAGCAGAA AGAAAAGTTA 
ATAAAGCGTC AAGAAGAGTT AGATAGGGGT TACAAATCAA TCATGGAACT GATGAATGTA 
CTTGAACTTC GGAAATATGA AGCTATTCAG TTAACTTTCA AACAGGTATC TAAGAACTTC 
AGTGAAGTAT TCCAGAAGTT AGTACCTGGT GGCAAAGCTA CTTTGGTGAT GAAGAAAGGA 
GATGTGGAGG GCAGTCAGTC TCAAGATGAA GGAGAAGGGA GTGGTGAGAG TGAGAGGGGT 
TCTGGCTCAC AAAGCAGTGT CCCATCAGTT GACCAGTTTA CTGGAGTTGG AATTAGGGTG 
TCATTTACAG GAAAACAAGG TGAAATGAGA GAAATGCAAC AGCTTTCAGG TGGACAGAAA 
TCCTTGGTAG CCCTTGCTCT GATTTTTGCC ATTCAGAAAT GTGACCCGGC TCCATTTTAC 
TTGTTTGATG AAATTGACCA GGCTCTGGAT GCTCAGCACA GAAAGGCTGT GTCAGATATG 
ATTATGGAAC TTGCTGTACA TGCTCAGTTT ATTACAACTA CTTTTAGGCC TGAACTGCTT 
GAGTCAGCTG ACAAATTCTA TGGTGTAAAG TTCAGAAATA AGGTTAGTCA TATTGATGTG 
ATCACAGCAG AGATGGCCAA AGACTTTGTA GAAGATGATA CCACACATGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity.
Nucleic acids research44(13)6309-17(2016 Jul)
Orgil O,Mor H,Matityahu A,Onn I

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SMC3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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