P5CR cDNA ORF clone, Leishmania infantum JPCM5

Gene
Clones
gRNAs

Summary

Gene Symbol	P5CR
Entrez Gene ID	10966489
Full Name	pyrroline-5-carboxylate reductase
Gene Type	protein-coding
Organism	Leishmania infantum JPCM5

mRNA and Protein(s)

mRNA	Protein	Name
XM_003392308.1	XP_003392356.1	pyrroline-5-carboxylate reductase

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Rogers MB, Hilley JD, Dickens NJ, Wilkes J, Bates PA, Depledge DP, Harris D, Her Y, Herzyk P, Imamura H, Otto TD, Sanders M, Seeger K, Dujardin JC, Berriman M, Smith DF, Hertz-Fowler C, Mottram JC
Genome research21(12)2129-42(2011 Dec)

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC, Quail MA, Peters N, Adlem E, Tivey A, Aslett M, Kerhornou A, Ivens A, Fraser A, Rajandream MA, Carver T, Norbertczak H, Chillingworth T, Hance Z, Jagels K, Moule S, Ormond D, Rutter S, Squares R, Whitehead S, Rabbinowitsch E, Arrowsmith C, White B, Thurston S, Bringaud F, Baldauf SL, Faulconbridge A, Jeffares D, Depledge DP, Oyola SO, Hilley JD, Brito LO, Tosi LR, Barrell B, Cruz AK, Mottram JC, Smith DF, Berriman M
Nature genetics39(7)839-47(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following P5CR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the P5CR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OLc07742	XM_003392308.1 Latest version!	Leishmania infantum JPCM5 pyrroline-5-carboxylate reductase (P5CR), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

P5CR ( XM_003392308.1 ) cDNA ORF clone, Leishmania infantum JPCM5 -> XP_003392356.1 Leishmania infantum JPCM5 pyrroline-5-carboxylate reductase (P5CR), partial mRNA.

Price & Availability↑

CloneID	OLc07742
Clone ID Related Accession (Same CDS sequence)	XM_003392308.1
Accession Version	XM_003392308.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 819bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-07-15
Organism	Leishmania infantum JPCM5
Product	pyrroline-5-carboxylate reductase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_009397). COMPLETENESS: incomplete on both ends.

ATGTCGGACC TGAAGATTGG TTTCTTGGGA TGTGGCAGCA TGGGTGAATG CATCATGGCA 
GGTATGCTGA AGGCCAAGGC GTTAGGGCCA GAGAATACCT TTGTTTGCAA TCGAAGCGCG 
TCTACAAATG AACGGCTGGT TTCCCTGTAC CAGGTGAGGA GTGTGAGTGC TGTTGAGCTG 
GCTGAACAGT CGGATATCAT CATGCTGGGC GTGAAGCCGT ACGGGATTGT GCCTGTTCTG 
GAGACGATCA AGGAGAAGAT AACACCCTCC AAGCTCGTTA TATCCATGGC TGCCGGTGTA 
CCTACAGCAA CGATCGAAAA CCATTGCCCT CCGAAAACAA AAGTCGTGCG GGTGATGCCG 
AACATTCCTT CATTCGTGGG GGAGGGAGTA ACATCGATCA GTGGTAACTC TGCTGTGACG 
CTTGATGACG AGGCGGTAGT GGTGAAGCTG TTCAGTGCGA TTGGAAAGGC GTACCTTGTG 
GCGGAGTCGG CGATCCACGG AGTCGTCGGT GTGGCCGGGT CTTCCCCCGC GTATGTTTTC 
ATGTTTATGG AGGCGCTGAG CGACGGCGCT GTGCGTGGTG GTATTCCCCG AGCGCAGTCC 
TATGAAATGG CTGCTCAGGC CGTTCTCGGT GCGGCAAAAA TGCTGCAGGA GAGCGGCAAA 
ACACCTGGCG CTCTGAAGGA CATGGTTTGC TCGCCGGGCG GGACAACCAT CGAGGCCGTT 
CGTTTTCTGG AGAAAGGCGG GATGCGCTCA TCTATTATTG AAGCGATGAT TCAGTGTATG 
GAAAAGTCTA AGGAATTCGA GAGAATGTAT AGCGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_003392356.1
CDS	1..819
Translation	MSDLKIGFLGCGSMGECIMAGMLKAKALGPENTFVCNRSASTNERLVSLYQVRSVSAVELAEQSDIIMLGVKPYGIVPVLETIKEKITPSKLVISMAAGVPTATIENHCPPKTKVVRVMPNIPSFVGEGVTSISGNSAVTLDDEAVVVKLFSAIGKAYLVAESAIHGVVGVAGSSPAYVFMFMEALSDGAVRGGIPRAQSYEMAAQAVLGAAKMLQESGKTPGALKDMVCSPGGTTIEAVRFLEKGGMRSSIIEAMIQCMEKSKEFERMYSE

Target ORF information:

RefSeq Version	XM_003392308.1
Organism	Leishmania infantum JPCM5
Definition	Leishmania infantum JPCM5 pyrroline-5-carboxylate reductase (P5CR), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_003392308.1

ORF Insert Sequence:

ATGTCGGACC TGAAGATTGG TTTCTTGGGA TGTGGCAGCA TGGGTGAATG CATCATGGCA 
GGTATGCTGA AGGCCAAGGC GTTAGGGCCA GAGAATACCT TTGTTTGCAA TCGAAGCGCG 
TCTACAAATG AACGGCTGGT TTCCCTGTAC CAGGTGAGGA GTGTGAGTGC TGTTGAGCTG 
GCTGAACAGT CGGATATCAT CATGCTGGGC GTGAAGCCGT ACGGGATTGT GCCTGTTCTG 
GAGACGATCA AGGAGAAGAT AACACCCTCC AAGCTCGTTA TATCCATGGC TGCCGGTGTA 
CCTACAGCAA CGATCGAAAA CCATTGCCCT CCGAAAACAA AAGTCGTGCG GGTGATGCCG 
AACATTCCTT CATTCGTGGG GGAGGGAGTA ACATCGATCA GTGGTAACTC TGCTGTGACG 
CTTGATGACG AGGCGGTAGT GGTGAAGCTG TTCAGTGCGA TTGGAAAGGC GTACCTTGTG 
GCGGAGTCGG CGATCCACGG AGTCGTCGGT GTGGCCGGGT CTTCCCCCGC GTATGTTTTC 
ATGTTTATGG AGGCGCTGAG CGACGGCGCT GTGCGTGGTG GTATTCCCCG AGCGCAGTCC 
TATGAAATGG CTGCTCAGGC CGTTCTCGGT GCGGCAAAAA TGCTGCAGGA GAGCGGCAAA 
ACACCTGGCG CTCTGAAGGA CATGGTTTGC TCGCCGGGCG GGACAACCAT CGAGGCCGTT 
CGTTTTCTGG AGAAAGGCGG GATGCGCTCA TCTATTATTG AAGCGATGAT TCAGTGTATG 
GAAAAGTCTA AGGAATTCGA GAGAATGTAT AGCGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Genome research21(12)2129-42(2011 Dec)
Rogers MB,Hilley JD,Dickens NJ,Wilkes J,Bates PA,Depledge DP,Harris D,Her Y,Herzyk P,Imamura H,Otto TD,Sanders M,Seeger K,Dujardin JC,Berriman M,Smith DF,Hertz-Fowler C,Mottram JC

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Nature genetics39(7)839-47(2007 Jul)
Peacock CS,Seeger K,Harris D,Murphy L,Ruiz JC,Quail MA,Peters N,Adlem E,Tivey A,Aslett M,Kerhornou A,Ivens A,Fraser A,Rajandream MA,Carver T,Norbertczak H,Chillingworth T,Hance Z,Jagels K,Moule S,Ormond D,Rutter S,Squares R,Whitehead S,Rabbinowitsch E,Arrowsmith C,White B,Thurston S,Bringaud F,Baldauf SL,Faulconbridge A,Jeffares D,Depledge DP,Oyola SO,Hilley JD,Brito LO,Tosi LR,Barrell B,Cruz AK,Mottram JC,Smith DF,Berriman M

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P5CR cDNA ORF clone, Leishmania infantum JPCM5

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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