Gene Symbol | Cdc20 |
Entrez Gene ID | 107995 |
Full Name | cell division cycle 20 |
Synonyms | 2310042N09Rik,C87100,p55CDC |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Cdc20 cDNA ORF clone
Gene Symbol | Cdc20 |
Entrez Gene ID | 107995 |
Full Name | cell division cycle 20 |
Synonyms | 2310042N09Rik,C87100,p55CDC |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_023223.2 | NP_075712.2 | cell division cycle protein 20 homolog |
Drosophila melanogaster (fruit fly) | fzy | NP_477501.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009338 | XP_310009.4 |
Oryza sativa (rice) | Os04g0599800 | NP_001053754.1 |
Xenopus tropicalis (tropical clawed frog) | cdc20 | NP_988945.1 |
Homo sapiens (human) | CDC20 | NP_001246.2 |
CDC20 | XP_001090604.2 | |
Danio rerio (zebrafish) | cdc20 | NP_998245.1 |
Eremothecium gossypii | AGOS_AFL014C | NP_985534.1 |
Schizosaccharomyces pombe (fission yeast) | slp1 | NP_593161.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01236 | XP_003714140.1 |
Oryza sativa (rice) | Os09g0242300 | NP_001062648.2 |
Pan troglodytes (chimpanzee) | CDC20 | NP_001230901.1 |
Canis lupus familiaris (dog) | CDC20 | XP_003639578.1 |
Bos taurus (cattle) | CDC20 | NP_001075905.1 |
Mus musculus (house mouse) | Cdc20 | NP_075712.2 |
Rattus norvegicus (Norway rat) | Cdc20 | NP_741990.1 |
Kluyveromyces lactis | KLLA0F10791g | XP_455571.1 |
Neurospora crassa | NCU02616 | XP_965019.1 |
Oryza sativa (rice) | Os02g0700100 | NP_001047837.1 |
Gallus gallus (chicken) | CDC20 | NP_001006536.1 |
Saccharomyces cerevisiae (baker's yeast) | CDC20 | NP_011399.1 |
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Cdc20 hypomorphism causes chromatin bridging and chromosome misalignment, revealing a requirement for Cdc20 in efficient sister chromosome separation and chromosome-microtubule attachment.
Title: Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.
The physiologically effective threshold level of Cdc20 is high for female meiosis I.
Title: Cdc20 is critical for meiosis I and fertility of female mice.
Results indicate that Cdc20 also contributes to post-anaphase activation of the APC/C.
Title: Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F.
Results indicate that the spindle assembly checkpoint-mediated inhibition of Cdc20 is an important tumor-suppressing mechanism.
Title: Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice.
Data show that the BubR1 N terminus binds to Cdc20 to inhibit APC/C activity in interphase, thereby allowing accumulation of cyclin B in G(2) phase prior to mitosis onset.
Title: BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase.
The following Cdc20 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdc20 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu18934 | |
Clone ID Related Accession (Same CDS sequence) | NM_023223.2 | |
Accession Version | NM_023223.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-07 | |
Organism | Mus musculus(house mouse) | |
Product | cell division cycle protein 20 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY736811.1, AK168650.1 and AV499208.1. On Jan 16, 2008 this sequence version replaced NM_023223.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003215.1, AK160204.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGCAGT TCGTGTTCGA GAGCGATTTG CACTCACTGC TTCAACTGGA CGCACCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_075712.2 |
CDS | 223..1722 |
Translation |
Target ORF information:
Target ORF information:
|
NM_023223.2 |
1 | ATGGCGCAGT TCGTGTTCGA GAGCGATTTG CACTCACTGC TTCAACTGGA CGCACCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. |