Gene Symbol | Junb |
Entrez Gene ID | 16477 |
Full Name | jun B proto-oncogene |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Junb cDNA ORF clone
gRNAs
Gene Symbol | Junb |
Entrez Gene ID | 16477 |
Full Name | jun B proto-oncogene |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_008416.3 | NP_032442.1 | transcription factor jun-B |
Pan troglodytes (chimpanzee) | JUNB | XP_524126.2 |
Homo sapiens (human) | JUNB | NP_002220.1 |
Canis lupus familiaris (dog) | JUNB | XP_003639770.1 |
Rattus norvegicus (Norway rat) | Junb | NP_068608.2 |
Bos taurus (cattle) | JUNB | NP_001069124.1 |
Xenopus tropicalis (tropical clawed frog) | junb | NP_001037955.1 |
JUNB | XP_001109775.2 | |
Mus musculus (house mouse) | Junb | NP_032442.1 |
AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection.
Vierbuchen T, Ling E, Cowley CJ, Couch CH, Wang X, Harmin DA, Roberts CWM, Greenberg ME
Molecular cell68(6)1067-1082.e12(2017 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that JunB is a nonredundant regulator of transcriptional programs that support Th17 cell identity and restrain alternative Th1 and Treg cell fates.
Title: JunB promotes Th17 cell identity and restrains alternative CD4
the present data demonstrates for the first time that JunB plays an important role in the formation of embryonic vascular networks.
Title: JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin.
BATF/JUN-B and BATF/C-JUN complexes play important roles in OA cartilage destruction through regulating anabolic and catabolic gene expression in chondrocytes.
Title: Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.
Study shows that myeloid deletion of JUNB dampens immune polarization and reshapes disease outcomes during infection with both P. berghei and N. brasiliensis by limiting type 1 and type 2 responses, respectively. Thus, JUNB is an important regulator of myeloid responses to both type 1 and type 2 infections in vivo.
Title: Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections.
JunB and c-Jun expression in post-mitotic oligodendrocytes is mostly dispensable for the maintainance of white matter tracts throughout adult life, even under demyelinating conditions.
Title: Deletion of Jun proteins in adult oligodendrocytes does not perturb cell survival, or myelin maintenance in vivo.
The following Junb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Junb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu19537 | |
Clone ID Related Accession (Same CDS sequence) | NM_008416.3 | |
Accession Version | NM_008416.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor jun-B | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163703.4, AK141592.1 and BY515688.1. On Mar 24, 2011 this sequence version replaced NM_008416.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end. |
1 | ATGTGCACGA AAATGGAACA GCCTTTCTAT CACGACGACT CTTACGCAGC GGCGGGATAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032442.1 |
CDS | 320..1354 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTGCACGA AAATGGAACA GCCTTTCTAT CACGACGACT CTTACGCAGC GGCGGGATAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection. |