Gene Symbol | Wee2 |
Entrez Gene ID | 381759 |
Full Name | WEE1 homolog 2 (S. pombe) |
Synonyms | Gm1065,Wee1B |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Wee2 cDNA ORF clone
Gene Symbol | Wee2 |
Entrez Gene ID | 381759 |
Full Name | WEE1 homolog 2 (S. pombe) |
Synonyms | Gm1065,Wee1B |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006506327.3 | XP_006506390.1 | wee1-like protein kinase 2 isoform X2 |
XM_006506326.4 | XP_006506389.1 | wee1-like protein kinase 2 isoform X1 |
XM_006506326.3 | XP_006506389.1 | wee1-like protein kinase 2 isoform X1 |
XM_006506327.4 | XP_006506390.1 | wee1-like protein kinase 2 isoform X2 |
NM_201370.2 | NP_958758.2 | wee1-like protein kinase 2 |
Bos taurus (cattle) | WEE2 | XP_002687121.1 |
Rattus norvegicus (Norway rat) | Wee2 | XP_006236426.1 |
Homo sapiens (human) | WEE2 | NP_001099028.1 |
WEE2 | NP_001099016.1 | |
Gallus gallus (chicken) | WEE2 | XP_004937931.1 |
Canis lupus familiaris (dog) | WEE2 | XP_532748.3 |
Mus musculus (house mouse) | Wee2 | NP_958758.2 |
Danio rerio (zebrafish) | wee2 | NP_001038367.1 |
Xenopus tropicalis (tropical clawed frog) | wee2 | XP_004912526.1 |
Pan troglodytes (chimpanzee) | WEE2 | XP_519504.3 |
CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Yu C, Zhang YL, Pan WW, Li XM, Wang ZW, Ge ZJ, Zhou JJ, Cang Y, Tong C, Sun QY, Fan HY
Science (New York, N.Y.)342(6165)1518-21(2013 Dec)
Ser 15 of WEE1B is a potential PKA phosphorylation target in G2/M transition in one-cell stage mouse embryos.
Liu C, Liu Y, Liu Y, Wu D, Luan Z, Wang E, Yu B
Molecular medicine reports7(6)1929-37(2013 Jun)
MARF1 regulates essential oogenic processes in mice.
Su YQ, Sugiura K, Sun F, Pendola JK, Cox GA, Handel MA, Schimenti JC, Eppig JJ
Science (New York, N.Y.)335(6075)1496-9(2012 Mar)
Protein tyrosine kinase Wee1B is essential for metaphase II exit in mouse oocytes.
Oh JS, Susor A, Conti M
Science (New York, N.Y.)332(6028)462-5(2011 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
WEE1B acts as a direct downstream substrate of protein kinase A (PKA) and that Ser 15 of WEE1B is a potential PKA phosphorylation target in the G2/M transition of mouse embryos.
Title: Ser 15 of WEE1B is a potential PKA phosphorylation target in G2/M transition in one-cell stage mouse embryos.
findings demonstrate that exit from metaphase requires not only a proteolytic degradation of cyclin B but also the inhibitory phosphorylation of Cdc2 by Wee1B
Title: Protein tyrosine kinase Wee1B is essential for metaphase II exit in mouse oocytes.
Wee1B is a key maturation-promoting-factor inhibitory kinase in mouse oocytes, functions downstream of PKA, and is required for maintaining meiotic arrest.
Title: Wee1B is an oocyte-specific kinase involved in the control of meiotic arrest in the mouse.
The following Wee2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wee2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu18090 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506326.4 , XM_006506326.3 , NM_201370.2 | |
Accession Version | NM_201370.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-15 | |
Organism | Mus musculus(house mouse) | |
Product | wee1-like protein kinase 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY725757.1, AK139573.1 and CJ200934.1. On Apr 2, 2008 this sequence version replaced NM_201370.1. ##Evidence-Data-START## Transcript exon combination :: AK139573.1, BC080784.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCGACA CAGAGACTGA CCAGGGACTG AACAAGAAAT TAAGCTTCTC CTTTTGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_958758.2 |
CDS | 367..2034 |
Translation |
Target ORF information:
Target ORF information:
|
NM_201370.2 |
1 | ATGGCCGACA CAGAGACTGA CCAGGGACTG AACAAGAAAT TAAGCTTCTC CTTTTGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu18090 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506326.4 , XM_006506326.3 , NM_201370.2 | |
Accession Version | XM_006506326.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | wee1-like protein kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006506326.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCGACA CAGAGACTGA CCAGGGACTG AACAAGAAAT TAAGCTTCTC CTTTTGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506389.1 |
CDS | 392..2059 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506326.3 |
1 | ATGGCCGACA CAGAGACTGA CCAGGGACTG AACAAGAAAT TAAGCTTCTC CTTTTGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37405 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506327.3 , XM_006506327.4 | |
Accession Version | XM_006506327.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | wee1-like protein kinase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006506327.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAGAATT CGCTGGGTCA GCCAGAGATT TCTCTGCTAG AGAAGCTCTC CTCCCGAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506390.1 |
CDS | 342..1691 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506327.3 |
1 | ATGCAGAATT CGCTGGGTCA GCCAGAGATT TCTCTGCTAG AGAAGCTCTC CTCCCGAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37405 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506327.3 , XM_006506327.4 | |
Accession Version | XM_006506327.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | wee1-like protein kinase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006506327.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAGAATT CGCTGGGTCA GCCAGAGATT TCTCTGCTAG AGAAGCTCTC CTCCCGAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506390.1 |
CDS | 494..1843 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506327.4 |
1 | ATGCAGAATT CGCTGGGTCA GCCAGAGATT TCTCTGCTAG AGAAGCTCTC CTCCCGAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu18090 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506326.4 , XM_006506326.3 , NM_201370.2 | |
Accession Version | XM_006506326.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | wee1-like protein kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006506326.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCGACA CAGAGACTGA CCAGGGACTG AACAAGAAAT TAAGCTTCTC CTTTTGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506389.1 |
CDS | 544..2211 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506326.4 |
1 | ATGGCCGACA CAGAGACTGA CCAGGGACTG AACAAGAAAT TAAGCTTCTC CTTTTGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. |
Ser 15 of WEE1B is a potential PKA phosphorylation target in G2/M transition in one-cell stage mouse embryos. |
MARF1 regulates essential oogenic processes in mice. |
Protein tyrosine kinase Wee1B is essential for metaphase II exit in mouse oocytes. |