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Akirin2 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Akirin2
Entrez Gene ID 433693
Full Name akirin 2
Synonyms 2700059D21Rik,AA114675,AA522011,AU019887,Akirin-2
General protein information
Preferred Names

akirin 2

Names

akirin-2
akirin2
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

4

4|4 A5

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001007589.3 NP_001007590.2 akirin-2
XM_011250060.3 XP_011248362.1 akirin-2 isoform X1
XM_011250060.2 XP_011248362.1 akirin-2 isoform X1

Pathways from BioSystems


Homologies


LOC700914 XP_001089230.1
Gallus gallus (chicken) AKIRIN2 NP_001180524.1
Danio rerio (zebrafish) akirin2 NP_998459.2
Canis lupus familiaris (dog) AKIRIN2 XP_542340.3
Drosophila melanogaster (fruit fly) akirin NP_729249.1
Xenopus tropicalis (tropical clawed frog) akirin2 NP_988914.1
Bos taurus (cattle) AKIRIN2 NP_001103557.1
Mus musculus (house mouse) Akirin2 NP_001007590.2
Anopheles gambiae (African malaria mosquito) AgaP_AGAP006809 XP_308938.4
Homo sapiens (human) AKIRIN2 NP_060534.1
Pan troglodytes (chimpanzee) AKIRIN2 NP_001238836.1
Rattus norvegicus (Norway rat) Akirin2 NP_001035003.1

Gene Ontology


Bibliography

Related articles in PubMed

Akirin2 is essential for the formation of the cerebral cortex.
Bosch PJ, Fuller LC, Sleeth CM, Weiner JA
Neural development11(1)21(2016 11)

Akirin2-Mediated Transcriptional Control by Recruiting SWI/SNF Complex in B Cells.
Tartey S, Takeuchi O
Critical reviews in immunology36(5)395-406(2016)

Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses.
Tartey S, Matsushita K, Imamura T, Wakabayashi A, Ori D, Mino T, Takeuchi O
Journal of immunology (Baltimore, Md. : 1950)195(2)519-27(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data demonstrate a previously-unsuspected role for Akirin2 in early cortical development and, given its known nuclear roles, suggest that it may act to regulate gene expression patterns critical for early progenitor cell behavior and cortical neuron production.
Title: Akirin2 is essential for the formation of the cerebral cortex.

this review discusses current understanding of the molecular mechanisms that have instrumental roles in governing the inflammatory response with special emphasis on Akirin2 in B cells
Title: Akirin2-Mediated Transcriptional Control by Recruiting SWI/SNF Complex in B Cells.

The nuclear protein akirin2 has an essential function in B cell activation and humoral immune responses.
Title: Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses.

The IkappaB-zeta-Akirin2-BAF60 complex physically links the NF-kappaB and SWI/SNF complexes in innate immune cell activation.
Title: Akirin2 is critical for inducing inflammatory genes by bridging I?B-? and the SWI/SNF complex.

The following Akirin2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Akirin2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu14599 XM_011250060.3
Latest version!		 Mus musculus akirin 2 (Akirin2), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
OMu14599 NM_001007589.3
Latest version!		 Mus musculus akirin 2 (Akirin2), mRNA. pcDNA3.1-C-(k)DYK or customized vector TBD $139.30
$199.00
View Old Accession Versions >>
OMu14599 XM_011250060.2 Mus musculus akirin 2 (Akirin2), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector TBD $139.30
$199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu14599
Clone ID Related Accession (Same CDS sequence) NM_001007589.3 , XM_011250060.3 , XM_011250060.2
Accession Version XM_011250060.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 606bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product akirin-2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011250060.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA 
TCTCCGAAGC GGAGGCGGTG CGCGCCTTTG TCGGCGCCGG CTTCGGCTGC CGCCTCCCCT 
GCCGCCGCCA CCGCCGCCGC CGCCGCCTCG GCCGCGGCCG CCTCGCCGCA GAAGTATCTC 
CGGATGGAGC CTTCCCCCTT CGGCGACGTC TCTTCCCGGC TCACCACAGA ACAAATTCTG 
TACAACATAA AACAGGAATA TAAACGCATG CAGAAGAGAA GACATTTAGA AGCTAGTTTT 
CAGCAGGCAG ATCCAGGTTG TACTTCCGAT TCACAGCCAC ATGCATTTCT CATCAGTGGA 
CCAGCATCAC CAGGGACTTC ATCTGCAACA TCCTCACCAT TAAAAAAAGA ACAGCCCTTA 
TTTACTCTAA GGCAGGTTGG AATGATCTGT GAACGTTTGT TGAAAGAACG GGAAGAGAAA 
GTTCGAGAAG AATATGAAGA AATACTGAAT ACAAAACTTG CAGAACAATA TGATGCTTTT 
GTGAAGTTTA CGCATGATCA GATAATGCGG CGATATGGAG AACAGCCTGC TAGTTATGTT 
TCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011248362.1
CDS218..823
Translation

Target ORF information:

RefSeq Version XM_011250060.3
Organism Mus musculus(house mouse)
Definition Mus musculus akirin 2 (Akirin2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250060.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA 
TCTCCGAAGC GGAGGCGGTG CGCGCCTTTG TCGGCGCCGG CTTCGGCTGC CGCCTCCCCT 
GCCGCCGCCA CCGCCGCCGC CGCCGCCTCG GCCGCGGCCG CCTCGCCGCA GAAGTATCTC 
CGGATGGAGC CTTCCCCCTT CGGCGACGTC TCTTCCCGGC TCACCACAGA ACAAATTCTG 
TACAACATAA AACAGGAATA TAAACGCATG CAGAAGAGAA GACATTTAGA AGCTAGTTTT 
CAGCAGGCAG ATCCAGGTTG TACTTCCGAT TCACAGCCAC ATGCATTTCT CATCAGTGGA 
CCAGCATCAC CAGGGACTTC ATCTGCAACA TCCTCACCAT TAAAAAAAGA ACAGCCCTTA 
TTTACTCTAA GGCAGGTTGG AATGATCTGT GAACGTTTGT TGAAAGAACG GGAAGAGAAA 
GTTCGAGAAG AATATGAAGA AATACTGAAT ACAAAACTTG CAGAACAATA TGATGCTTTT 
GTGAAGTTTA CGCATGATCA GATAATGCGG CGATATGGAG AACAGCCTGC TAGTTATGTT 
TCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu14599
Clone ID Related Accession (Same CDS sequence) NM_001007589.3 , XM_011250060.3 , XM_011250060.2
Accession Version NM_001007589.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 606bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-11-04
Organism Mus musculus(house mouse)
Product akirin-2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL807397.6, BE336109.1, BC082305.1 and AK005836.1. On Feb 9, 2006 this sequence version replaced NM_001007589.2. ##Evidence-Data-START## Transcript exon combination :: AK005836.1, CB573520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA 
TCTCCGAAGC GGAGGCGGTG CGCGCCTTTG TCGGCGCCGG CTTCGGCTGC CGCCTCCCCT 
GCCGCCGCCA CCGCCGCCGC CGCCGCCTCG GCCGCGGCCG CCTCGCCGCA GAAGTATCTC 
CGGATGGAGC CTTCCCCCTT CGGCGACGTC TCTTCCCGGC TCACCACAGA ACAAATTCTG 
TACAACATAA AACAGGAATA TAAACGCATG CAGAAGAGAA GACATTTAGA AGCTAGTTTT 
CAGCAGGCAG ATCCAGGTTG TACTTCCGAT TCACAGCCAC ATGCATTTCT CATCAGTGGA 
CCAGCATCAC CAGGGACTTC ATCTGCAACA TCCTCACCAT TAAAAAAAGA ACAGCCCTTA 
TTTACTCTAA GGCAGGTTGG AATGATCTGT GAACGTTTGT TGAAAGAACG GGAAGAGAAA 
GTTCGAGAAG AATATGAAGA AATACTGAAT ACAAAACTTG CAGAACAATA TGATGCTTTT 
GTGAAGTTTA CGCATGATCA GATAATGCGG CGATATGGAG AACAGCCTGC TAGTTATGTT 
TCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001007590.2
CDS431..1036
Translation

Target ORF information:

RefSeq Version NM_001007589.3
Organism Mus musculus(house mouse)
Definition Mus musculus akirin 2 (Akirin2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001007589.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA 
TCTCCGAAGC GGAGGCGGTG CGCGCCTTTG TCGGCGCCGG CTTCGGCTGC CGCCTCCCCT 
GCCGCCGCCA CCGCCGCCGC CGCCGCCTCG GCCGCGGCCG CCTCGCCGCA GAAGTATCTC 
CGGATGGAGC CTTCCCCCTT CGGCGACGTC TCTTCCCGGC TCACCACAGA ACAAATTCTG 
TACAACATAA AACAGGAATA TAAACGCATG CAGAAGAGAA GACATTTAGA AGCTAGTTTT 
CAGCAGGCAG ATCCAGGTTG TACTTCCGAT TCACAGCCAC ATGCATTTCT CATCAGTGGA 
CCAGCATCAC CAGGGACTTC ATCTGCAACA TCCTCACCAT TAAAAAAAGA ACAGCCCTTA 
TTTACTCTAA GGCAGGTTGG AATGATCTGT GAACGTTTGT TGAAAGAACG GGAAGAGAAA 
GTTCGAGAAG AATATGAAGA AATACTGAAT ACAAAACTTG CAGAACAATA TGATGCTTTT 
GTGAAGTTTA CGCATGATCA GATAATGCGG CGATATGGAG AACAGCCTGC TAGTTATGTT 
TCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu14599
Clone ID Related Accession (Same CDS sequence) NM_001007589.3 , XM_011250060.3 , XM_011250060.2
Accession Version XM_011250060.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 606bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product akirin-2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011250060.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA 
TCTCCGAAGC GGAGGCGGTG CGCGCCTTTG TCGGCGCCGG CTTCGGCTGC CGCCTCCCCT 
GCCGCCGCCA CCGCCGCCGC CGCCGCCTCG GCCGCGGCCG CCTCGCCGCA GAAGTATCTC 
CGGATGGAGC CTTCCCCCTT CGGCGACGTC TCTTCCCGGC TCACCACAGA ACAAATTCTG 
TACAACATAA AACAGGAATA TAAACGCATG CAGAAGAGAA GACATTTAGA AGCTAGTTTT 
CAGCAGGCAG ATCCAGGTTG TACTTCCGAT TCACAGCCAC ATGCATTTCT CATCAGTGGA 
CCAGCATCAC CAGGGACTTC ATCTGCAACA TCCTCACCAT TAAAAAAAGA ACAGCCCTTA 
TTTACTCTAA GGCAGGTTGG AATGATCTGT GAACGTTTGT TGAAAGAACG GGAAGAGAAA 
GTTCGAGAAG AATATGAAGA AATACTGAAT ACAAAACTTG CAGAACAATA TGATGCTTTT 
GTGAAGTTTA CGCATGATCA GATAATGCGG CGATATGGAG AACAGCCTGC TAGTTATGTT 
TCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011248362.1
CDS220..825
Translation

Target ORF information:

RefSeq Version XM_011250060.2
Organism Mus musculus(house mouse)
Definition Mus musculus akirin 2 (Akirin2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250060.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA 
TCTCCGAAGC GGAGGCGGTG CGCGCCTTTG TCGGCGCCGG CTTCGGCTGC CGCCTCCCCT 
GCCGCCGCCA CCGCCGCCGC CGCCGCCTCG GCCGCGGCCG CCTCGCCGCA GAAGTATCTC 
CGGATGGAGC CTTCCCCCTT CGGCGACGTC TCTTCCCGGC TCACCACAGA ACAAATTCTG 
TACAACATAA AACAGGAATA TAAACGCATG CAGAAGAGAA GACATTTAGA AGCTAGTTTT 
CAGCAGGCAG ATCCAGGTTG TACTTCCGAT TCACAGCCAC ATGCATTTCT CATCAGTGGA 
CCAGCATCAC CAGGGACTTC ATCTGCAACA TCCTCACCAT TAAAAAAAGA ACAGCCCTTA 
TTTACTCTAA GGCAGGTTGG AATGATCTGT GAACGTTTGT TGAAAGAACG GGAAGAGAAA 
GTTCGAGAAG AATATGAAGA AATACTGAAT ACAAAACTTG CAGAACAATA TGATGCTTTT 
GTGAAGTTTA CGCATGATCA GATAATGCGG CGATATGGAG AACAGCCTGC TAGTTATGTT 
TCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Akirin2 is essential for the formation of the cerebral cortex.
Neural development11(1)21(2016 11)
Bosch PJ,Fuller LC,Sleeth CM,Weiner JA


book

Akirin2-Mediated Transcriptional Control by Recruiting SWI/SNF Complex in B Cells.
Critical reviews in immunology36(5)395-406(2016)
Tartey S,Takeuchi O


book

Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses.
Journal of immunology (Baltimore, Md. : 1950)195(2)519-27(2015 Jul)
Tartey S,Matsushita K,Imamura T,Wakabayashi A,Ori D,Mino T,Takeuchi O