Gene Symbol | Akirin2 |
Entrez Gene ID | 433693 |
Full Name | akirin 2 |
Synonyms | 2700059D21Rik,AA114675,AA522011,AU019887,Akirin-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Akirin2 cDNA ORF clone
gRNAs
Gene Symbol | Akirin2 |
Entrez Gene ID | 433693 |
Full Name | akirin 2 |
Synonyms | 2700059D21Rik,AA114675,AA522011,AU019887,Akirin-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001007589.3 | NP_001007590.2 | akirin-2 |
XM_011250060.3 | XP_011248362.1 | akirin-2 isoform X1 |
XM_011250060.2 | XP_011248362.1 | akirin-2 isoform X1 |
LOC700914 | XP_001089230.1 | |
Gallus gallus (chicken) | AKIRIN2 | NP_001180524.1 |
Danio rerio (zebrafish) | akirin2 | NP_998459.2 |
Canis lupus familiaris (dog) | AKIRIN2 | XP_542340.3 |
Drosophila melanogaster (fruit fly) | akirin | NP_729249.1 |
Xenopus tropicalis (tropical clawed frog) | akirin2 | NP_988914.1 |
Bos taurus (cattle) | AKIRIN2 | NP_001103557.1 |
Mus musculus (house mouse) | Akirin2 | NP_001007590.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006809 | XP_308938.4 |
Homo sapiens (human) | AKIRIN2 | NP_060534.1 |
Pan troglodytes (chimpanzee) | AKIRIN2 | NP_001238836.1 |
Rattus norvegicus (Norway rat) | Akirin2 | NP_001035003.1 |
Akirin2 is essential for the formation of the cerebral cortex.
Bosch PJ, Fuller LC, Sleeth CM, Weiner JA
Neural development11(1)21(2016 11)
Akirin2-Mediated Transcriptional Control by Recruiting SWI/SNF Complex in B Cells.
Tartey S, Takeuchi O
Critical reviews in immunology36(5)395-406(2016)
Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses.
Tartey S, Matsushita K, Imamura T, Wakabayashi A, Ori D, Mino T, Takeuchi O
Journal of immunology (Baltimore, Md. : 1950)195(2)519-27(2015 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data demonstrate a previously-unsuspected role for Akirin2 in early cortical development and, given its known nuclear roles, suggest that it may act to regulate gene expression patterns critical for early progenitor cell behavior and cortical neuron production.
Title: Akirin2 is essential for the formation of the cerebral cortex.
this review discusses current understanding of the molecular mechanisms that have instrumental roles in governing the inflammatory response with special emphasis on Akirin2 in B cells
Title: Akirin2-Mediated Transcriptional Control by Recruiting SWI/SNF Complex in B Cells.
The nuclear protein akirin2 has an essential function in B cell activation and humoral immune responses.
Title: Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses.
The IkappaB-zeta-Akirin2-BAF60 complex physically links the NF-kappaB and SWI/SNF complexes in innate immune cell activation.
Title: Akirin2 is critical for inducing inflammatory genes by bridging I?B-? and the SWI/SNF complex.
The following Akirin2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Akirin2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu14599 | |
Clone ID Related Accession (Same CDS sequence) | NM_001007589.3 , XM_011250060.3 , XM_011250060.2 | |
Accession Version | XM_011250060.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | akirin-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011250060.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011248362.1 |
CDS | 218..823 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu14599 | |
Clone ID Related Accession (Same CDS sequence) | NM_001007589.3 , XM_011250060.3 , XM_011250060.2 | |
Accession Version | NM_001007589.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-04 | |
Organism | Mus musculus(house mouse) | |
Product | akirin-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL807397.6, BE336109.1, BC082305.1 and AK005836.1. On Feb 9, 2006 this sequence version replaced NM_001007589.2. ##Evidence-Data-START## Transcript exon combination :: AK005836.1, CB573520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001007590.2 |
CDS | 431..1036 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu14599 | |
Clone ID Related Accession (Same CDS sequence) | NM_001007589.3 , XM_011250060.3 , XM_011250060.2 | |
Accession Version | XM_011250060.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | akirin-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011250060.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011248362.1 |
CDS | 220..825 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCGCTGCT GAGCCCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Akirin2 is essential for the formation of the cerebral cortex. |
Akirin2-Mediated Transcriptional Control by Recruiting SWI/SNF Complex in B Cells. |
Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses. |