Akirin2 cDNA ORF clone, Rattus norvegicus(Norway rat)
Gene Symbol | Akirin2 |
Entrez Gene ID | 297968 |
Full Name | akirin 2 |
Synonyms | FBI1,RGD1307791 |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_001039914.2 | NP_001035003.1 | akirin-2 |
XM_008763614.2 | XP_008761836.1 | akirin-2 isoform X1 |

LOC700914 | XP_001089230.1 | |
Gallus gallus (chicken) | AKIRIN2 | NP_001180524.1 |
Danio rerio (zebrafish) | akirin2 | NP_998459.2 |
Canis lupus familiaris (dog) | AKIRIN2 | XP_542340.3 |
Drosophila melanogaster (fruit fly) | akirin | NP_729249.1 |
Xenopus tropicalis (tropical clawed frog) | akirin2 | NP_988914.1 |
Bos taurus (cattle) | AKIRIN2 | NP_001103557.1 |
Mus musculus (house mouse) | Akirin2 | NP_001007590.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006809 | XP_308938.4 |
Homo sapiens (human) | AKIRIN2 | NP_060534.1 |
Pan troglodytes (chimpanzee) | AKIRIN2 | NP_001238836.1 |
Rattus norvegicus (Norway rat) | Akirin2 | NP_001035003.1 |

Related articles in PubMed
FBI1/Akirin2 promotes tumorigenicity and metastasis of Lewis lung carcinoma cells.
Komiya Y, Akiyama H, Sakumoto R, Tashiro F
Biochemical and biophysical research communications444(3)382-6(2014 Feb)
A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.
Armour SM, Bennett EJ, Braun CR, Zhang XY, McMahon SB, Gygi SP, Harper JW, Sinclair DA
Molecular and cellular biology33(8)1487-502(2013 Apr)
The FBI1/Akirin2 target gene, BCAM, acts as a suppressive oncogene.
Akiyama H, Iwahana Y, Suda M, Yoshimura A, Kogai H, Nagashima A, Ohtsuka H, Komiya Y, Tashiro F
PloS one8(11)e78716(2013)
A novel binding factor of 14-3-3beta functions as a transcriptional repressor and promotes anchorage-independent growth, tumorigenicity, and metastasis.
Komiya Y, Kurabe N, Katagiri K, Ogawa M, Sugiyama A, Kawasaki Y, Tashiro F
The Journal of biological chemistry283(27)18753-64(2008 Jul)
Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice.
Goto A, Matsushita K, Gesellchen V, El Chamy L, Kuttenkeuler D, Takeuchi O, Hoffmann JA, Akira S, Boutros M, Reichhart JM
Nature immunology9(1)97-104(2008 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
results suggest that FBI1/Akirin2 plays an important role in oncogenesis of LLC1 lung carcinoma cells, and this protein may also serve as an oncogene in other cancers
Title: FBI1/Akirin2 promotes tumorigenicity and metastasis of Lewis lung carcinoma cells.
Data indicate that the 14-3-3beta-FBI1/Akirin2 complex bound to the basal cell adhesion molecule (BCAM) promoter and repressed transcription.
Title: The FBI1/Akirin2 target gene, BCAM, acts as a suppressive oncogene.
The following Akirin2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Akirin2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13396 | |
Clone ID Related Accession (Same CDS sequence) | NM_001039914.2 | |
Accession Version | NM_001039914.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | akirin-2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB234867.1. On Feb 23, 2013 this sequence version replaced NM_001039914.1. ##Evidence-Data-START## Transcript exon combination :: AB234867.1, FM074314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCACTGCT TAGCCCGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001035003.1 |
CDS | 199..804 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCACTGCT TAGCCCGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa45485 | |
Clone ID Related Accession (Same CDS sequence) | XM_008763614.2 | |
Accession Version | XM_008763614.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | akirin-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763614.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCACTGCT TAGCCCGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008761836.1 |
CDS | 449..1069 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGTGCG GAGCCACTCT GAAAAGGACT CTGGATTTCG ACCCACTGCT TAGCCCGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
FBI1/Akirin2 promotes tumorigenicity and metastasis of Lewis lung carcinoma cells. |
![]() |
A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. |
![]() |
The FBI1/Akirin2 target gene, BCAM, acts as a suppressive oncogene. |
![]() |
A novel binding factor of 14-3-3beta functions as a transcriptional repressor and promotes anchorage-independent growth, tumorigenicity, and metastasis. |
![]() |
Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. |