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Mcm8 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Mcm8
Entrez Gene ID 66634
Full Name minichromosome maintenance 8 homologous recombination repair factor
Synonyms 5730432L01Rik
General protein information
Preferred Names

minichromosome maintenance 8 homologous recombination repair factor

Names

DNA helicase MCM8
DNA replication licensing factor MCM8
minichromosome maintenance deficient 8
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

2

2|2 F2

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_025676.4 NP_079952.2 DNA helicase MCM8 isoform b
NM_001291054.1 NP_001277983.1 DNA helicase MCM8 isoform a
XM_006500021.3 XP_006500084.1 DNA helicase MCM8 isoform X1

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) MCM8 XP_534352.2
Mus musculus (house mouse) Mcm8 NP_079952.2
Gallus gallus (chicken) MCM8 XP_004935348.1
Pan troglodytes (chimpanzee) MCM8 XP_001166933.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP002580 XP_312356.3
Homo sapiens (human) MCM8 NP_001268449.1
Arabidopsis thaliana (thale cress) MCM8 NP_187577.1
Rattus norvegicus (Norway rat) Mcm8 NP_001099984.1
Danio rerio (zebrafish) LOC100333576 XP_002665161.2
Xenopus tropicalis (tropical clawed frog) mcm8 NP_001072344.1
MCM8 XP_001115843.1
Bos taurus (cattle) MCM8 NP_001179965.1
Oryza sativa (rice) Os05g0464100 NP_001055777.1

Gene Ontology


Bibliography

Related articles in PubMed

The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.
O'Driscoll M
The Journal of pathology241(2)192-207(2017 Jan)

MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination.
Lutzmann M, Grey C, Traver S, Ganier O, Maya-Mendoza A, Ranisavljevic N, Bernex F, Nishiyama A, Montel N, Gavois E, Forichon L, de Massy B, M?chali M
Molecular cell47(4)523-34(2012 Aug)

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T, Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA, Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts P, Muramatsu M, Okazaki Y, Kawai J, Hayashizaki Y
Genome research13(6B)1273-89(2003 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MCM8 and MCM9 form a complex and that they coregulate their stability.
Title: MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination.

The following Mcm8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcm8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu30786 XM_006500021.3
Latest version!		 Mus musculus minichromosome maintenance 8 homologous recombination repair factor (Mcm8), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OMu14448 NM_025676.4
Latest version!		 Mus musculus minichromosome maintenance 8 homologous recombination repair factor (Mcm8), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
OMu17128 NM_001291054.1
Latest version!		 Mus musculus minichromosome maintenance 8 homologous recombination repair factor (Mcm8), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu30786
Clone ID Related Accession (Same CDS sequence) XM_006500021.3
Accession Version XM_006500021.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1725bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product DNA helicase MCM8 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006500021.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
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361
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481
541
601
661
721
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841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGAGTGGTG CTTATAGAGG CAGAGGTTTT GGACGAGGAA GATTCCAAAG CTGGAAAAGA 
GGAAGAGGTG GTGGGAACTT CTCAGGAAGG TGGAGAGAAA GAGAAAACAG AGTTGACCTG 
AATGAAGCTT CAGGAAAGCA CGCTTCTGCA CAAGCCTCAC AACCGTTACT TCAACAGTCA 
ACATTGGATC AGTTTATCCC GTATAAGGGC TGGAAGCTTT ACTTCTCTGA AGTTTACAGT 
AATAACTCTC CCTTTATTGA GAAGATTCAA GCATTTGAGA AATTTTTCAC AAGGCATATC 
GACTTATACG ATAAGGATGA AATAGAAAGA AAAGGAAGCA TTTTGGTGGA TTTTAAAGAA 
CTGACAAAAG CTGATGAAAT AACTAACTTG ATACCCGATA TAGAAAACGC ACTAAGAGAT 
GCCCCTGAGA AAACACTGGC GTGTATGGGG CTGGCAATAC ATCAGGTATT AACTAAGGAC 
CTTGAAAGGC ATGCCGCCGA ATTACAAGCT CAAGAGGGAT TGTCTAACGG TGGAGAGACA 
ATGGTAAATG TACCACATAT TTATGCAAGA GTGTACAACT ATGAGCCCTT GACACACCTC 
AAGAATATCC GAGCAACTTG CTATGGGAAA TACATCTCTA TACGAGGGAC TGTGGTCCGG 
GTCAGCAACA TAAAGCCTCT TTGCACCAAC ATGGCTTTTC AGTGCGCTGC ATGTGGAGAG 
ATTCAGAGCT TTCCTCTGCC AGATGGAAAA TACACCCTTC CTACAAAGTG TCCTGTGCCT 
GCGTGCCGAG GGAGGTCATT TGCTCCACTG CGCAGCTCTC CTCTCACAGT TACACTGGAC 
TGGCAGTTGA TCAAAATCCA GGAGCTGATG TCTGATGCAC AGAGAGAAGC TGGTCGGATC 
CCTCGGACGA TAGAATGTGA ACTTGTTCAC GATCTTGTAG ATAGTTGTGT CCCAGGAGAT 
ACAGTGACTG TTACTGGAAT TGTCAAAGTC TCCAATTCTG AAGAAGGTTC TCGAAATAAG 
AATGATAAGT GCATGTTCCT TTTGTACATT GAGGCAAATT CTGTTAGCAA CAGCAAGGGG 
CCGAAAGCAC AGACTGCAGA AGATGGTTGC AAGCATGGGA CACTGATGGA GTTCTCCCTT 
AAAGACCTCT ATGCCATCCG AGAGATCCAG GCTGAAGAGA ACCTGCTCAA GCTCGTTGTC 
AACTCACTCT GTCCTGTCAT TTTTGGTCAT GAACTCGTCA AAGCAGGTCT GACGTTAGCA 
CTCTTTGGCG GTAGCCAGAA GTACGCAGAT GACAAAAACA GAATTCCCAT TCGAGGAGAC 
CCACATGTCC TGATTGTTGG AGATCCAGGC TTGGGGAAGA GTCAGATGCT ACAGGCAGCA 
TGCAACGTGG CGCCACGTGG TGTGTATGTT TGTGGAAATA CCACCACCAG CTCTGGTCTC 
ACTGTGACTC TTTCAAAGGA CAGTTCCTCT GGAGATTTTG CTTTGGAAGC TGGTGCCCTT 
GTACTTGGTG ACCAAGGCAT CTGTGGAATA GATGAATTTG ATAAAATGGG GAACCAACAT 
CAAGCCCTGT TAGAAGCCAT GGAACAGCAG AGTATTAGCC TTGCGAAGGC TGGGGTAGTT 
TGCAGCCTCC CTGCAAGAAC TTCCATTATT GCTGCTGCAA ATCCAGTCGG AGGACACTAC 
AATAAAGCCA GAACGGTTTC TGAGAATTTA AAATACGCCA AATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006500084.1
CDS345..2069
Translation

Target ORF information:

RefSeq Version XM_006500021.3
Organism Mus musculus(house mouse)
Definition Mus musculus minichromosome maintenance 8 homologous recombination repair factor (Mcm8), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006500021.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGAGTGGTG CTTATAGAGG CAGAGGTTTT GGACGAGGAA GATTCCAAAG CTGGAAAAGA 
GGAAGAGGTG GTGGGAACTT CTCAGGAAGG TGGAGAGAAA GAGAAAACAG AGTTGACCTG 
AATGAAGCTT CAGGAAAGCA CGCTTCTGCA CAAGCCTCAC AACCGTTACT TCAACAGTCA 
ACATTGGATC AGTTTATCCC GTATAAGGGC TGGAAGCTTT ACTTCTCTGA AGTTTACAGT 
AATAACTCTC CCTTTATTGA GAAGATTCAA GCATTTGAGA AATTTTTCAC AAGGCATATC 
GACTTATACG ATAAGGATGA AATAGAAAGA AAAGGAAGCA TTTTGGTGGA TTTTAAAGAA 
CTGACAAAAG CTGATGAAAT AACTAACTTG ATACCCGATA TAGAAAACGC ACTAAGAGAT 
GCCCCTGAGA AAACACTGGC GTGTATGGGG CTGGCAATAC ATCAGGTATT AACTAAGGAC 
CTTGAAAGGC ATGCCGCCGA ATTACAAGCT CAAGAGGGAT TGTCTAACGG TGGAGAGACA 
ATGGTAAATG TACCACATAT TTATGCAAGA GTGTACAACT ATGAGCCCTT GACACACCTC 
AAGAATATCC GAGCAACTTG CTATGGGAAA TACATCTCTA TACGAGGGAC TGTGGTCCGG 
GTCAGCAACA TAAAGCCTCT TTGCACCAAC ATGGCTTTTC AGTGCGCTGC ATGTGGAGAG 
ATTCAGAGCT TTCCTCTGCC AGATGGAAAA TACACCCTTC CTACAAAGTG TCCTGTGCCT 
GCGTGCCGAG GGAGGTCATT TGCTCCACTG CGCAGCTCTC CTCTCACAGT TACACTGGAC 
TGGCAGTTGA TCAAAATCCA GGAGCTGATG TCTGATGCAC AGAGAGAAGC TGGTCGGATC 
CCTCGGACGA TAGAATGTGA ACTTGTTCAC GATCTTGTAG ATAGTTGTGT CCCAGGAGAT 
ACAGTGACTG TTACTGGAAT TGTCAAAGTC TCCAATTCTG AAGAAGGTTC TCGAAATAAG 
AATGATAAGT GCATGTTCCT TTTGTACATT GAGGCAAATT CTGTTAGCAA CAGCAAGGGG 
CCGAAAGCAC AGACTGCAGA AGATGGTTGC AAGCATGGGA CACTGATGGA GTTCTCCCTT 
AAAGACCTCT ATGCCATCCG AGAGATCCAG GCTGAAGAGA ACCTGCTCAA GCTCGTTGTC 
AACTCACTCT GTCCTGTCAT TTTTGGTCAT GAACTCGTCA AAGCAGGTCT GACGTTAGCA 
CTCTTTGGCG GTAGCCAGAA GTACGCAGAT GACAAAAACA GAATTCCCAT TCGAGGAGAC 
CCACATGTCC TGATTGTTGG AGATCCAGGC TTGGGGAAGA GTCAGATGCT ACAGGCAGCA 
TGCAACGTGG CGCCACGTGG TGTGTATGTT TGTGGAAATA CCACCACCAG CTCTGGTCTC 
ACTGTGACTC TTTCAAAGGA CAGTTCCTCT GGAGATTTTG CTTTGGAAGC TGGTGCCCTT 
GTACTTGGTG ACCAAGGCAT CTGTGGAATA GATGAATTTG ATAAAATGGG GAACCAACAT 
CAAGCCCTGT TAGAAGCCAT GGAACAGCAG AGTATTAGCC TTGCGAAGGC TGGGGTAGTT 
TGCAGCCTCC CTGCAAGAAC TTCCATTATT GCTGCTGCAA ATCCAGTCGG AGGACACTAC 
AATAAAGCCA GAACGGTTTC TGAGAATTTA AAATACGCCA AATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu14448
Clone ID Related Accession (Same CDS sequence) NM_025676.4
Accession Version NM_025676.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2418bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-23
Organism Mus musculus(house mouse)
Product DNA helicase MCM8 isoform b
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY766288.1, BC052070.1 and AK133858.1. On Mar 22, 2014 this sequence version replaced NM_025676.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: BC052070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164142, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGAGTGGTG CTTATAGAGG CAGAGGTTTT GGACGAGGAA GATTCCAAAG CTGGAAAAGA 
GGAAGAGGTG GTGGGAACTT CTCAGGAAGG TGGAGAGAAA GAGAAAACAG AGTTGACCTG 
AATGAAGCTT CAGGAAAGCA CGCTTCTGTT TACAGTAATA ACTCTCCCTT TATTGAGAAG 
ATTCAAGCAT TTGAGAAATT TTTCACAAGG CATATCGACT TATACGATAA GGATGAAATA 
GAAAGAAAAG GAAGCATTTT GGTGGATTTT AAAGAACTGA CAAAAGCTGA TGAAATAACT 
AACTTGATAC CCGATATAGA AAACGCACTA AGAGATGCCC CTGAGAAAAC ACTGGCGTGT 
ATGGGGCTGG CAATACATCA GGTATTAACT AAGGACCTTG AAAGGCATGC CGCCGAATTA 
CAAGCTCAAG AGGGATTGTC TAACGGTGGA GAGACAATGG TAAATGTACC ACATATTTAT 
GCAAGAGTGT ACAACTATGA GCCCTTGACA CACCTCAAGA ATATCCGAGC AACTTGCTAT 
GGGAAATACA TCTCTATACG AGGGACTGTG GTCCGGGTCA GCAACATAAA GCCTCTTTGC 
ACCAACATGG CTTTTCAGTG CGCTGCATGT GGAGAGATTC AGAGCTTTCC TCTGCCAGAT 
GGAAAATACA CCCTTCCTAC AAAGTGTCCT GTGCCTGCGT GCCGAGGGAG GTCATTTGCT 
CCACTGCGCA GCTCTCCTCT CACAGTTACA CTGGACTGGC AGTTGATCAA AATCCAGGAG 
CTGATGTCTG ATGCACAGAG AGAAGCTGGT CGGATCCCTC GGACGATAGA ATGTGAACTT 
GTTCACGATC TTGTAGATAG TTGTGTCCCA GGAGATACAG TGACTGTTAC TGGAATTGTC 
AAAGTCTCCA ATTCTGAAGA AGGTTCTCGA AATAAGAATG ATAAGTGCAT GTTCCTTTTG 
TACATTGAGG CAAATTCTGT TAGCAACAGC AAGGGGCCGA AAGCACAGAC TGCAGAAGAT 
GGTTGCAAGC ATGGGACACT GATGGAGTTC TCCCTTAAAG ACCTCTATGC CATCCGAGAG 
ATCCAGGCTG AAGAGAACCT GCTCAAGCTC GTTGTCAACT CACTCTGTCC TGTCATTTTT 
GGTCATGAAC TCGTCAAAGC AGGTCTGACG TTAGCACTCT TTGGCGGTAG CCAGAAGTAC 
GCAGATGACA AAAACAGAAT TCCCATTCGA GGAGACCCAC ATGTCCTGAT TGTTGGAGAT 
CCAGGCTTGG GGAAGAGTCA GATGCTACAG GCAGCATGCA ACGTGGCGCC ACGTGGTGTG 
TATGTTTGTG GAAATACCAC CACCAGCTCT GGTCTCACTG TGACTCTTTC AAAGGACAGT 
TCCTCTGGAG ATTTTGCTTT GGAAGCTGGT GCCCTTGTAC TTGGTGACCA AGGCATCTGT 
GGAATAGATG AATTTGATAA AATGGGGAAC CAACATCAAG CCCTGTTAGA AGCCATGGAA 
CAGCAGAGTA TTAGCCTTGC GAAGGCTGGG GTAGTTTGCA GCCTCCCTGC AAGAACTTCC 
ATTATTGCTG CTGCAAATCC AGTCGGAGGA CACTACAATA AAGCCAGAAC GGTTTCTGAG 
AATTTAAAGA TGGGGAGTGC CCTACTGTCC AGATTCGATT TGGTCTTTAT CTTGTTAGAT 
ACGCCAAATG AACAGCATGA CCACTTACTT TCTGAACATG TGATCGCGAT AAGAGCTGGG 
AAGCAGAAAG CGGTTAGCAG TGCCACAGTC ACTCGTGTGC TCAGTCAAGA CTCAAATACT 
TCTGTACTTG AAGTGGTTTC TGAGAAACCA TTATCAGAAA GACTAAAGGT GGCTCCTGGA 
GAACAGACAG ATCCGATTCC ACATCAGCTG TTGAGGAAGT ACATTGGCTA TGCACGGCAG 
TATGTCCACC CAAGGTTATC TACGGACGCT GCTCAGGCCC TTCAGGATTT CTACCTGGAG 
CTCCGCAAGC AGAGCCAGCG CGTGGGCAGC TCACCCATCA CCACTCGGCA GCTGGAGTCT 
TTGATCCGTC TGACAGAGGC ACGGGCAAGG TTAGAATTGA GAGAGGAAGC AACTAGAGAA 
GATGCTGAAG ATATAATTGA AATTATGAAG CATAGCATGC TAGGAACTTA CTCAGATGAA 
TTCGGAAACC TGGACTTTGA GCGATCCCAG CATGGCTCTG GGATGAGCAA CAGGTCAACA 
GCAAAAAGAT TTATTTCTGC TCTCAACAGC ATTGCTGAAA GAACTTATAA CAACATATTT 
CAATATCATC AACTTCGTCA GATTGCTAAA GAACTAAACA TTCAGGTTGC CGATTTTGAA 
AACTTCATTG GATCACTGAA TGACCAAGGT TATCTCTTGA AGAAAGGCCC AAAGATTTAC 
CAACTTCAAA CTATGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_079952.2
CDS350..2767
Translation

Target ORF information:

RefSeq Version NM_025676.4
Organism Mus musculus(house mouse)
Definition Mus musculus minichromosome maintenance 8 homologous recombination repair factor (Mcm8), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_025676.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGAGTGGTG CTTATAGAGG CAGAGGTTTT GGACGAGGAA GATTCCAAAG CTGGAAAAGA 
GGAAGAGGTG GTGGGAACTT CTCAGGAAGG TGGAGAGAAA GAGAAAACAG AGTTGACCTG 
AATGAAGCTT CAGGAAAGCA CGCTTCTGTT TACAGTAATA ACTCTCCCTT TATTGAGAAG 
ATTCAAGCAT TTGAGAAATT TTTCACAAGG CATATCGACT TATACGATAA GGATGAAATA 
GAAAGAAAAG GAAGCATTTT GGTGGATTTT AAAGAACTGA CAAAAGCTGA TGAAATAACT 
AACTTGATAC CCGATATAGA AAACGCACTA AGAGATGCCC CTGAGAAAAC ACTGGCGTGT 
ATGGGGCTGG CAATACATCA GGTATTAACT AAGGACCTTG AAAGGCATGC CGCCGAATTA 
CAAGCTCAAG AGGGATTGTC TAACGGTGGA GAGACAATGG TAAATGTACC ACATATTTAT 
GCAAGAGTGT ACAACTATGA GCCCTTGACA CACCTCAAGA ATATCCGAGC AACTTGCTAT 
GGGAAATACA TCTCTATACG AGGGACTGTG GTCCGGGTCA GCAACATAAA GCCTCTTTGC 
ACCAACATGG CTTTTCAGTG CGCTGCATGT GGAGAGATTC AGAGCTTTCC TCTGCCAGAT 
GGAAAATACA CCCTTCCTAC AAAGTGTCCT GTGCCTGCGT GCCGAGGGAG GTCATTTGCT 
CCACTGCGCA GCTCTCCTCT CACAGTTACA CTGGACTGGC AGTTGATCAA AATCCAGGAG 
CTGATGTCTG ATGCACAGAG AGAAGCTGGT CGGATCCCTC GGACGATAGA ATGTGAACTT 
GTTCACGATC TTGTAGATAG TTGTGTCCCA GGAGATACAG TGACTGTTAC TGGAATTGTC 
AAAGTCTCCA ATTCTGAAGA AGGTTCTCGA AATAAGAATG ATAAGTGCAT GTTCCTTTTG 
TACATTGAGG CAAATTCTGT TAGCAACAGC AAGGGGCCGA AAGCACAGAC TGCAGAAGAT 
GGTTGCAAGC ATGGGACACT GATGGAGTTC TCCCTTAAAG ACCTCTATGC CATCCGAGAG 
ATCCAGGCTG AAGAGAACCT GCTCAAGCTC GTTGTCAACT CACTCTGTCC TGTCATTTTT 
GGTCATGAAC TCGTCAAAGC AGGTCTGACG TTAGCACTCT TTGGCGGTAG CCAGAAGTAC 
GCAGATGACA AAAACAGAAT TCCCATTCGA GGAGACCCAC ATGTCCTGAT TGTTGGAGAT 
CCAGGCTTGG GGAAGAGTCA GATGCTACAG GCAGCATGCA ACGTGGCGCC ACGTGGTGTG 
TATGTTTGTG GAAATACCAC CACCAGCTCT GGTCTCACTG TGACTCTTTC AAAGGACAGT 
TCCTCTGGAG ATTTTGCTTT GGAAGCTGGT GCCCTTGTAC TTGGTGACCA AGGCATCTGT 
GGAATAGATG AATTTGATAA AATGGGGAAC CAACATCAAG CCCTGTTAGA AGCCATGGAA 
CAGCAGAGTA TTAGCCTTGC GAAGGCTGGG GTAGTTTGCA GCCTCCCTGC AAGAACTTCC 
ATTATTGCTG CTGCAAATCC AGTCGGAGGA CACTACAATA AAGCCAGAAC GGTTTCTGAG 
AATTTAAAGA TGGGGAGTGC CCTACTGTCC AGATTCGATT TGGTCTTTAT CTTGTTAGAT 
ACGCCAAATG AACAGCATGA CCACTTACTT TCTGAACATG TGATCGCGAT AAGAGCTGGG 
AAGCAGAAAG CGGTTAGCAG TGCCACAGTC ACTCGTGTGC TCAGTCAAGA CTCAAATACT 
TCTGTACTTG AAGTGGTTTC TGAGAAACCA TTATCAGAAA GACTAAAGGT GGCTCCTGGA 
GAACAGACAG ATCCGATTCC ACATCAGCTG TTGAGGAAGT ACATTGGCTA TGCACGGCAG 
TATGTCCACC CAAGGTTATC TACGGACGCT GCTCAGGCCC TTCAGGATTT CTACCTGGAG 
CTCCGCAAGC AGAGCCAGCG CGTGGGCAGC TCACCCATCA CCACTCGGCA GCTGGAGTCT 
TTGATCCGTC TGACAGAGGC ACGGGCAAGG TTAGAATTGA GAGAGGAAGC AACTAGAGAA 
GATGCTGAAG ATATAATTGA AATTATGAAG CATAGCATGC TAGGAACTTA CTCAGATGAA 
TTCGGAAACC TGGACTTTGA GCGATCCCAG CATGGCTCTG GGATGAGCAA CAGGTCAACA 
GCAAAAAGAT TTATTTCTGC TCTCAACAGC ATTGCTGAAA GAACTTATAA CAACATATTT 
CAATATCATC AACTTCGTCA GATTGCTAAA GAACTAAACA TTCAGGTTGC CGATTTTGAA 
AACTTCATTG GATCACTGAA TGACCAAGGT TATCTCTTGA AGAAAGGCCC AAAGATTTAC 
CAACTTCAAA CTATGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu17128
Clone ID Related Accession (Same CDS sequence) NM_001291054.1
Accession Version NM_001291054.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2502bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product DNA helicase MCM8 isoform a
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY766288.1, BC046780.1 and BC052070.1. On Mar 22, 2014 this sequence version replaced XM_006500020.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: AK133858.1, BC046780.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGAGTGGTG CTTATAGAGG CAGAGGTTTT GGACGAGGAA GATTCCAAAG CTGGAAAAGA 
GGAAGAGGTG GTGGGAACTT CTCAGGAAGG TGGAGAGAAA GAGAAAACAG AGTTGACCTG 
AATGAAGCTT CAGGAAAGCA CGCTTCTGCA CAAGCCTCAC AACCGTTACT TCAACAGTCA 
ACATTGGATC AGTTTATCCC GTATAAGGGC TGGAAGCTTT ACTTCTCTGA AGTTTACAGT 
AATAACTCTC CCTTTATTGA GAAGATTCAA GCATTTGAGA AATTTTTCAC AAGGCATATC 
GACTTATACG ATAAGGATGA AATAGAAAGA AAAGGAAGCA TTTTGGTGGA TTTTAAAGAA 
CTGACAAAAG CTGATGAAAT AACTAACTTG ATACCCGATA TAGAAAACGC ACTAAGAGAT 
GCCCCTGAGA AAACACTGGC GTGTATGGGG CTGGCAATAC ATCAGGTATT AACTAAGGAC 
CTTGAAAGGC ATGCCGCCGA ATTACAAGCT CAAGAGGGAT TGTCTAACGG TGGAGAGACA 
ATGGTAAATG TACCACATAT TTATGCAAGA GTGTACAACT ATGAGCCCTT GACACACCTC 
AAGAATATCC GAGCAACTTG CTATGGGAAA TACATCTCTA TACGAGGGAC TGTGGTCCGG 
GTCAGCAACA TAAAGCCTCT TTGCACCAAC ATGGCTTTTC AGTGCGCTGC ATGTGGAGAG 
ATTCAGAGCT TTCCTCTGCC AGATGGAAAA TACACCCTTC CTACAAAGTG TCCTGTGCCT 
GCGTGCCGAG GGAGGTCATT TGCTCCACTG CGCAGCTCTC CTCTCACAGT TACACTGGAC 
TGGCAGTTGA TCAAAATCCA GGAGCTGATG TCTGATGCAC AGAGAGAAGC TGGTCGGATC 
CCTCGGACGA TAGAATGTGA ACTTGTTCAC GATCTTGTAG ATAGTTGTGT CCCAGGAGAT 
ACAGTGACTG TTACTGGAAT TGTCAAAGTC TCCAATTCTG AAGAAGGTTC TCGAAATAAG 
AATGATAAGT GCATGTTCCT TTTGTACATT GAGGCAAATT CTGTTAGCAA CAGCAAGGGG 
CCGAAAGCAC AGACTGCAGA AGATGGTTGC AAGCATGGGA CACTGATGGA GTTCTCCCTT 
AAAGACCTCT ATGCCATCCG AGAGATCCAG GCTGAAGAGA ACCTGCTCAA GCTCGTTGTC 
AACTCACTCT GTCCTGTCAT TTTTGGTCAT GAACTCGTCA AAGCAGGTCT GACGTTAGCA 
CTCTTTGGCG GTAGCCAGAA GTACGCAGAT GACAAAAACA GAATTCCCAT TCGAGGAGAC 
CCACATGTCC TGATTGTTGG AGATCCAGGC TTGGGGAAGA GTCAGATGCT ACAGGCAGCA 
TGCAACGTGG CGCCACGTGG TGTGTATGTT TGTGGAAATA CCACCACCAG CTCTGGTCTC 
ACTGTGACTC TTTCAAAGGA CAGTTCCTCT GGAGATTTTG CTTTGGAAGC TGGTGCCCTT 
GTACTTGGTG ACCAAGGCAT CTGTGGAATA GATGAATTTG ATAAAATGGG GAACCAACAT 
CAAGCCCTGT TAGAAGCCAT GGAACAGCAG AGTATTAGCC TTGCGAAGGC TGGGGTAGTT 
TGCAGCCTCC CTGCAAGAAC TTCCATTATT GCTGCTGCAA ATCCAGTCGG AGGACACTAC 
AATAAAGCCA GAACGGTTTC TGAGAATTTA AAGATGGGGA GTGCCCTACT GTCCAGATTC 
GATTTGGTCT TTATCTTGTT AGATACGCCA AATGAACAGC ATGACCACTT ACTTTCTGAA 
CATGTGATCG CGATAAGAGC TGGGAAGCAG AAAGCGGTTA GCAGTGCCAC AGTCACTCGT 
GTGCTCAGTC AAGACTCAAA TACTTCTGTA CTTGAAGTGG TTTCTGAGAA ACCATTATCA 
GAAAGACTAA AGGTGGCTCC TGGAGAACAG ACAGATCCGA TTCCACATCA GCTGTTGAGG 
AAGTACATTG GCTATGCACG GCAGTATGTC CACCCAAGGT TATCTACGGA CGCTGCTCAG 
GCCCTTCAGG ATTTCTACCT GGAGCTCCGC AAGCAGAGCC AGCGCGTGGG CAGCTCACCC 
ATCACCACTC GGCAGCTGGA GTCTTTGATC CGTCTGACAG AGGCACGGGC AAGGTTAGAA 
TTGAGAGAGG AAGCAACTAG AGAAGATGCT GAAGATATAA TTGAAATTAT GAAGCATAGC 
ATGCTAGGAA CTTACTCAGA TGAATTCGGA AACCTGGACT TTGAGCGATC CCAGCATGGC 
TCTGGGATGA GCAACAGGTC AACAGCAAAA AGATTTATTT CTGCTCTCAA CAGCATTGCT 
GAAAGAACTT ATAACAACAT ATTTCAATAT CATCAACTTC GTCAGATTGC TAAAGAACTA 
AACATTCAGG TTGCCGATTT TGAAAACTTC ATTGGATCAC TGAATGACCA AGGTTATCTC 
TTGAAGAAAG GCCCAAAGAT TTACCAACTT CAAACTATGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001277983.1
CDS350..2851
Translation

Target ORF information:

RefSeq Version NM_001291054.1
Organism Mus musculus(house mouse)
Definition Mus musculus minichromosome maintenance 8 homologous recombination repair factor (Mcm8), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001291054.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGAGTGGTG CTTATAGAGG CAGAGGTTTT GGACGAGGAA GATTCCAAAG CTGGAAAAGA 
GGAAGAGGTG GTGGGAACTT CTCAGGAAGG TGGAGAGAAA GAGAAAACAG AGTTGACCTG 
AATGAAGCTT CAGGAAAGCA CGCTTCTGCA CAAGCCTCAC AACCGTTACT TCAACAGTCA 
ACATTGGATC AGTTTATCCC GTATAAGGGC TGGAAGCTTT ACTTCTCTGA AGTTTACAGT 
AATAACTCTC CCTTTATTGA GAAGATTCAA GCATTTGAGA AATTTTTCAC AAGGCATATC 
GACTTATACG ATAAGGATGA AATAGAAAGA AAAGGAAGCA TTTTGGTGGA TTTTAAAGAA 
CTGACAAAAG CTGATGAAAT AACTAACTTG ATACCCGATA TAGAAAACGC ACTAAGAGAT 
GCCCCTGAGA AAACACTGGC GTGTATGGGG CTGGCAATAC ATCAGGTATT AACTAAGGAC 
CTTGAAAGGC ATGCCGCCGA ATTACAAGCT CAAGAGGGAT TGTCTAACGG TGGAGAGACA 
ATGGTAAATG TACCACATAT TTATGCAAGA GTGTACAACT ATGAGCCCTT GACACACCTC 
AAGAATATCC GAGCAACTTG CTATGGGAAA TACATCTCTA TACGAGGGAC TGTGGTCCGG 
GTCAGCAACA TAAAGCCTCT TTGCACCAAC ATGGCTTTTC AGTGCGCTGC ATGTGGAGAG 
ATTCAGAGCT TTCCTCTGCC AGATGGAAAA TACACCCTTC CTACAAAGTG TCCTGTGCCT 
GCGTGCCGAG GGAGGTCATT TGCTCCACTG CGCAGCTCTC CTCTCACAGT TACACTGGAC 
TGGCAGTTGA TCAAAATCCA GGAGCTGATG TCTGATGCAC AGAGAGAAGC TGGTCGGATC 
CCTCGGACGA TAGAATGTGA ACTTGTTCAC GATCTTGTAG ATAGTTGTGT CCCAGGAGAT 
ACAGTGACTG TTACTGGAAT TGTCAAAGTC TCCAATTCTG AAGAAGGTTC TCGAAATAAG 
AATGATAAGT GCATGTTCCT TTTGTACATT GAGGCAAATT CTGTTAGCAA CAGCAAGGGG 
CCGAAAGCAC AGACTGCAGA AGATGGTTGC AAGCATGGGA CACTGATGGA GTTCTCCCTT 
AAAGACCTCT ATGCCATCCG AGAGATCCAG GCTGAAGAGA ACCTGCTCAA GCTCGTTGTC 
AACTCACTCT GTCCTGTCAT TTTTGGTCAT GAACTCGTCA AAGCAGGTCT GACGTTAGCA 
CTCTTTGGCG GTAGCCAGAA GTACGCAGAT GACAAAAACA GAATTCCCAT TCGAGGAGAC 
CCACATGTCC TGATTGTTGG AGATCCAGGC TTGGGGAAGA GTCAGATGCT ACAGGCAGCA 
TGCAACGTGG CGCCACGTGG TGTGTATGTT TGTGGAAATA CCACCACCAG CTCTGGTCTC 
ACTGTGACTC TTTCAAAGGA CAGTTCCTCT GGAGATTTTG CTTTGGAAGC TGGTGCCCTT 
GTACTTGGTG ACCAAGGCAT CTGTGGAATA GATGAATTTG ATAAAATGGG GAACCAACAT 
CAAGCCCTGT TAGAAGCCAT GGAACAGCAG AGTATTAGCC TTGCGAAGGC TGGGGTAGTT 
TGCAGCCTCC CTGCAAGAAC TTCCATTATT GCTGCTGCAA ATCCAGTCGG AGGACACTAC 
AATAAAGCCA GAACGGTTTC TGAGAATTTA AAGATGGGGA GTGCCCTACT GTCCAGATTC 
GATTTGGTCT TTATCTTGTT AGATACGCCA AATGAACAGC ATGACCACTT ACTTTCTGAA 
CATGTGATCG CGATAAGAGC TGGGAAGCAG AAAGCGGTTA GCAGTGCCAC AGTCACTCGT 
GTGCTCAGTC AAGACTCAAA TACTTCTGTA CTTGAAGTGG TTTCTGAGAA ACCATTATCA 
GAAAGACTAA AGGTGGCTCC TGGAGAACAG ACAGATCCGA TTCCACATCA GCTGTTGAGG 
AAGTACATTG GCTATGCACG GCAGTATGTC CACCCAAGGT TATCTACGGA CGCTGCTCAG 
GCCCTTCAGG ATTTCTACCT GGAGCTCCGC AAGCAGAGCC AGCGCGTGGG CAGCTCACCC 
ATCACCACTC GGCAGCTGGA GTCTTTGATC CGTCTGACAG AGGCACGGGC AAGGTTAGAA 
TTGAGAGAGG AAGCAACTAG AGAAGATGCT GAAGATATAA TTGAAATTAT GAAGCATAGC 
ATGCTAGGAA CTTACTCAGA TGAATTCGGA AACCTGGACT TTGAGCGATC CCAGCATGGC 
TCTGGGATGA GCAACAGGTC AACAGCAAAA AGATTTATTT CTGCTCTCAA CAGCATTGCT 
GAAAGAACTT ATAACAACAT ATTTCAATAT CATCAACTTC GTCAGATTGC TAAAGAACTA 
AACATTCAGG TTGCCGATTT TGAAAACTTC ATTGGATCAC TGAATGACCA AGGTTATCTC 
TTGAAGAAAG GCCCAAAGAT TTACCAACTT CAAACTATGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.
The Journal of pathology241(2)192-207(2017 Jan)
O'Driscoll M


book

MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination.
Molecular cell47(4)523-34(2012 Aug)
Lutzmann M,Grey C,Traver S,Ganier O,Maya-Mendoza A,Ranisavljevic N,Bernex F,Nishiyama A,Montel N,Gavois E,Forichon L,de Massy B,M?chali M


book

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Genome research13(6B)1273-89(2003 Jun)
Carninci P,Waki K,Shiraki T,Konno H,Shibata K,Itoh M,Aizawa K,Arakawa T,Ishii Y,Sasaki D,Bono H,Kondo S,Sugahara Y,Saito R,Osato N,Fukuda S,Sato K,Watahiki A,Hirozane-Kishikawa T,Nakamura M,Shibata Y,Yasunishi A,Kikuchi N,Yoshiki A,Kusakabe M,Gustincich S,Beisel K,Pavan W,Aidinis V,Nakagawara A,Held WA,Iwata H,Kono T,Nakauchi H,Lyons P,Wells C,Hume DA,Fagiolini M,Hensch TK,Brinkmeier M,Camper S,Hirota J,Mombaerts P,Muramatsu M,Okazaki Y,Kawai J,Hayashizaki Y