Loxl4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Loxl4
Entrez Gene ID	67573
Full Name	lysyl oxidase-like 4
Synonyms	4833426I20Rik,Loxc
General protein information	Preferred Names lysyl oxidase-like 4 Names lysyl oxidase homolog 4 lysyl oxidase-like protein 4 lysyl oxidase-related protein C
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA Protein Name

NM_053083.3 NP_444313.3 lysyl oxidase homolog 4 isoform 2 precursor

NM_001164311.1 NP_001157783.1 lysyl oxidase homolog 4 isoform 1 precursor
Pathways from BioSystems

mRNA	Protein	Name
NM_053083.3	NP_444313.3	lysyl oxidase homolog 4 isoform 2 precursor
NM_001164311.1	NP_001157783.1	lysyl oxidase homolog 4 isoform 1 precursor

Homologies

Homo sapiens (human)	LOXL4	NP_115587.6
Canis lupus familiaris (dog)	LOXL4	XP_543959.2
Mus musculus (house mouse)	Loxl4	NP_001157783.1
Gallus gallus (chicken)	LOXL4	XP_004942235.1
Danio rerio (zebrafish)	loxl4	XP_002664258.3
Xenopus tropicalis (tropical clawed frog)	loxl4	XP_002936486.1
Pan troglodytes (chimpanzee)	LOXL4	XP_521577.3
Rattus norvegicus (Norway rat)	Loxl4	NP_001101062.1
Bos taurus (cattle)	LOXL4	NP_776809.1
	LOXL4	XP_001096621.2

Gene Ontology
Bibliography

Related articles in PubMed

LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer.
Choi SK, Kim HS, Jin T, Moon WK
Oncotarget8(7)11977-11989(2017 Feb)

Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.
Zhang J, Liu Z, Zhang T, Lin Z, Li Z, Zhang A, Sun X, Gao J
Scientific reports633856(2016 Sep)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.
Pischon N, M?ki JM, Weisshaupt P, Heng N, Palamakumbura AH, N'Guessan P, Ding A, Radlanski R, Renz H, Bronckers TA, Myllyharju J, Kielbassa AM, Kleber BM, Bernimoulin JP, Trackman PC
Calcified tissue international85(2)119-26(2009 Aug)

Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage.
Ito H, Akiyama H, Iguchi H, Iyama K, Miyamoto M, Ohsawa K, Nakamura T
The Journal of biological chemistry276(26)24023-9(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results demonstrate that weak LOXL4 expression leads to remodeling of the extracellular matrix through induction of collagen synthesis, deposition, and structural changes.
Title: LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer.

The following Loxl4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Loxl4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09035	NM_053083.3 Latest version!	Mus musculus lysyl oxidase-like 4 (Loxl4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$447.30 $639.00
OMu09737	NM_001164311.1 Latest version!	Mus musculus lysyl oxidase-like 4 (Loxl4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Loxl4 ( NM_053083.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_444313.3 Mus musculus lysyl oxidase-like 4 (Loxl4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu09035
Clone ID Related Accession (Same CDS sequence)	NM_053083.3
Accession Version	NM_053083.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Mus musculus(house mouse)
Product	lysyl oxidase homolog 4 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124552.3, BY145829.1, AK014331.1 and BC053925.1. On Aug 27, 2009 this sequence version replaced NM_053083.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the middle portion of the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC068307.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTGGC CCCAACCACC CACCTTCTCC CTGTTCCTGC TACTGCTGCT AAGCCAAGCC 
CCTTCCAGCA GGCCACAGTC ATCAGGCACC AAGAAGCTCA GGCTTGTGGG GCCAACGGAC 
AGACCAGAGG AGGGCCGCTT GGAGGTGCTG CACCAGGGCC AGTGGGGCAC GGTGTGTGAT 
GATGACTTCG CTCTCCAGGA GGCTACTGTG GCCTGCCGAC AGCTGGGCTT TGAGTCAGCC 
TTGACCTGGG CACACAGTGC CAAGTATGGT CAAGGAGAGG GTCCCATCTG GCTGGACAAT 
GTTCGTTGTT TGGGCACCGA GAAGACCCTA GATCAGTGTG GCTCTAACGG CTGGGGTGTC 
AGTGACTGCA GACACTCAGA AGATGTTGGG GTGGTATGTC ACCCACGGCG CCAGCACGGA 
TATCACTCTG AGAAGGTCTC CAATGCCCTC GGGCCTCAGG GCCGGCGGCT AGAAGAGGTA 
CGGCTGAAAC CCATCCTCGC CAGTGCCAAA AGGCACAGCC CAGTGACTGA GGGGGCTGTG 
GAAGTACGGT ACGACGGCCA CTGGAGGCAG GTGTGTGACC AGGGCTGGAC CATGAACAAC 
AGCAGGGTTG TATGCGGGAT GCTGGGCTTT CCCAGTCAGA CATCTGTCAA CAGCCACTAC 
TACAGAAAAG TCTGGAATCT GAAGATGAAG GATCCCAAGT CTAGGCTCAA CAGCCTGACA 
AAAAAGAATT CCTTCTGGAT TCACCGGGTT GACTGTCTGG GGACAGAGCC CCACTTGGCC 
AAGTGCCAGG TACAGGTGGC TCCAGGAAGG GGCAAGCTTC GGCCAGCCTG TCCAGGCGGC 
ATGCACGCTG TGGTCAGCTG TGTGGCAGGG CCCCACTTCC GCCGACAGAA GCCAAAGCCG 
ACGCGCAAGG AGTCCCATGC AGAGGAGCTG AAAGTGCGCC TGCGCTCTGG GGCTCAGGTG 
GGTGAGGGCC GTGTGGAAGT GCTCATGAAC CGCCAGTGGG GCACAGTCTG TGACCACAGG 
TGGAACCTCA TCTCAGCCAG CGTCGTGTGT CGCCAGCTTG GCTTTGGCTC TGCCCGGGAG 
GCCCTTTTTG GGGCCCAGTT GGGTCAAGGG CTAGGACCCA TCCACCTGAG TGAGGTGCGC 
TGCCGGGGGT ATGAGCGGAC CCTGGGTGAC TGCCTTGCCC TGGAAGGGTC CCAGAATGGT 
TGTCAACATG CAAACGACGC TGCTGTCAGG TGCAACATCC CAGACATGGG CTTCCAGAAC 
AAGGTGCGCT TGGCTGGTGG GCGCAACTCC GAAGAGGGAG TGGTGGAGGT GCAGGTGGAG 
GTGAATGGGG TCCCACGATG GGGGACTGTA TGCAGTGACC ACTGGGGGCT CACCGAAGCC 
ATGGTGACCT GTCGGCAACT TGGTCTGGGA TTTGCCAACT TTGCTCTCAA GGACACCTGG 
TACTGGCAGG GGACACCAGA GGCCAAAGAA GTGGTGATGA GTGGAGTTCG CTGCTCAGGC 
ACAGAAATGG CCCTGCAGCA GTGTCAGAGA CATGGGCCCG TGCACTGTTC CCACGGCCCA 
GGGCGCTTCT CGGCTGGCGT TGCCTGTATG AACAGTGCTC CAGACCTCGT GATGAACGCC 
CAGCTGGTAC AAGAGACGGC GTACTTGGAG GATCGTCCAC TCAGCATGCT GTACTGTGCT 
CACGAGGAAA ACTGCCTTTC CAAGTCCGCT GATCACATGG ACTGGCCCTA CGGGTACCGG 
CGCTTGCTGC GCTTCTCCTC ACAGATCTAC AACCTTGGCC GGGCCGACTT CCGTCCCAAG 
GCTGGACGCC ACAGCTGGAT TTGGCACCAG TGCCACAGGC ACTACCACAG CATCGAAGTC 
TTCACTCATT ATGACCTGCT CACGCTCAAT GGCTCCAAGG TGGCCGAGGG ACACAAGGCC 
AGCTTCTGTC TAGAAGATAC AAACTGCCCC TCAGGAGTGC AGCGGCGCTA TGCATGTGCC 
AACTTTGGGG AACAGGGAGT GGCTGTAGGC TGCTGGGACA CCTACCGGCA TGACATCGAT 
TGCCAGTGGG TGGATATCAC AGATGTGGGT CCAGGGGACT ATATCTTCCA GGTGGTTGTG 
AACCCCACAA ACGATGTTGC AGAGTCCGAT TTCTCCAATA ACATGATACG GTGCCGCTGC 
AAGTATGATG GACAGCGAGT CTGGTTGCAC AACTGCCACA CAGGAGATTC CTACCGAGCC 
AATGCAGAGC TCTCCCTGGA GCAGGAACAG CGACTCAGGA ACAACTTGAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444313.3
CDS	106..2379
Translation	MMWPQPPTFSLFLLLLLSQAPSSRPQSSGTKKLRLVGPTDRPEEGRLEVLHQGQWGTVCDDDFALQEATVACRQLGFESALTWAHSAKYGQGEGPIWLDNVRCLGTEKTLDQCGSNGWGVSDCRHSEDVGVVCHPRRQHGYHSEKVSNALGPQGRRLEEVRLKPILASAKRHSPVTEGAVEVRYDGHWRQVCDQGWTMNNSRVVCGMLGFPSQTSVNSHYYRKVWNLKMKDPKSRLNSLTKKNSFWIHRVDCLGTEPHLAKCQVQVAPGRGKLRPACPGGMHAVVSCVAGPHFRRQKPKPTRKESHAEELKVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGAQLGQGLGPIHLSEVRCRGYERTLGDCLALEGSQNGCQHANDAAVRCNIPDMGFQNKVRLAGGRNSEEGVVEVQVEVNGVPRWGTVCSDHWGLTEAMVTCRQLGLGFANFALKDTWYWQGTPEAKEVVMSGVRCSGTEMALQQCQRHGPVHCSHGPGRFSAGVACMNSAPDLVMNAQLVQETAYLEDRPLSMLYCAHEENCLSKSADHMDWPYGYRRLLRFSSQIYNLGRADFRPKAGRHSWIWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPSGVQRRYACANFGEQGVAVGCWDTYRHDIDCQWVDITDVGPGDYIFQVVVNPTNDVAESDFSNNMIRCRCKYDGQRVWLHNCHTGDSYRANAELSLEQEQRLRNNLI

Target ORF information:

RefSeq Version	NM_053083.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysyl oxidase-like 4 (Loxl4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053083.3

ORF Insert Sequence:

ATGATGTGGC CCCAACCACC CACCTTCTCC CTGTTCCTGC TACTGCTGCT AAGCCAAGCC 
CCTTCCAGCA GGCCACAGTC ATCAGGCACC AAGAAGCTCA GGCTTGTGGG GCCAACGGAC 
AGACCAGAGG AGGGCCGCTT GGAGGTGCTG CACCAGGGCC AGTGGGGCAC GGTGTGTGAT 
GATGACTTCG CTCTCCAGGA GGCTACTGTG GCCTGCCGAC AGCTGGGCTT TGAGTCAGCC 
TTGACCTGGG CACACAGTGC CAAGTATGGT CAAGGAGAGG GTCCCATCTG GCTGGACAAT 
GTTCGTTGTT TGGGCACCGA GAAGACCCTA GATCAGTGTG GCTCTAACGG CTGGGGTGTC 
AGTGACTGCA GACACTCAGA AGATGTTGGG GTGGTATGTC ACCCACGGCG CCAGCACGGA 
TATCACTCTG AGAAGGTCTC CAATGCCCTC GGGCCTCAGG GCCGGCGGCT AGAAGAGGTA 
CGGCTGAAAC CCATCCTCGC CAGTGCCAAA AGGCACAGCC CAGTGACTGA GGGGGCTGTG 
GAAGTACGGT ACGACGGCCA CTGGAGGCAG GTGTGTGACC AGGGCTGGAC CATGAACAAC 
AGCAGGGTTG TATGCGGGAT GCTGGGCTTT CCCAGTCAGA CATCTGTCAA CAGCCACTAC 
TACAGAAAAG TCTGGAATCT GAAGATGAAG GATCCCAAGT CTAGGCTCAA CAGCCTGACA 
AAAAAGAATT CCTTCTGGAT TCACCGGGTT GACTGTCTGG GGACAGAGCC CCACTTGGCC 
AAGTGCCAGG TACAGGTGGC TCCAGGAAGG GGCAAGCTTC GGCCAGCCTG TCCAGGCGGC 
ATGCACGCTG TGGTCAGCTG TGTGGCAGGG CCCCACTTCC GCCGACAGAA GCCAAAGCCG 
ACGCGCAAGG AGTCCCATGC AGAGGAGCTG AAAGTGCGCC TGCGCTCTGG GGCTCAGGTG 
GGTGAGGGCC GTGTGGAAGT GCTCATGAAC CGCCAGTGGG GCACAGTCTG TGACCACAGG 
TGGAACCTCA TCTCAGCCAG CGTCGTGTGT CGCCAGCTTG GCTTTGGCTC TGCCCGGGAG 
GCCCTTTTTG GGGCCCAGTT GGGTCAAGGG CTAGGACCCA TCCACCTGAG TGAGGTGCGC 
TGCCGGGGGT ATGAGCGGAC CCTGGGTGAC TGCCTTGCCC TGGAAGGGTC CCAGAATGGT 
TGTCAACATG CAAACGACGC TGCTGTCAGG TGCAACATCC CAGACATGGG CTTCCAGAAC 
AAGGTGCGCT TGGCTGGTGG GCGCAACTCC GAAGAGGGAG TGGTGGAGGT GCAGGTGGAG 
GTGAATGGGG TCCCACGATG GGGGACTGTA TGCAGTGACC ACTGGGGGCT CACCGAAGCC 
ATGGTGACCT GTCGGCAACT TGGTCTGGGA TTTGCCAACT TTGCTCTCAA GGACACCTGG 
TACTGGCAGG GGACACCAGA GGCCAAAGAA GTGGTGATGA GTGGAGTTCG CTGCTCAGGC 
ACAGAAATGG CCCTGCAGCA GTGTCAGAGA CATGGGCCCG TGCACTGTTC CCACGGCCCA 
GGGCGCTTCT CGGCTGGCGT TGCCTGTATG AACAGTGCTC CAGACCTCGT GATGAACGCC 
CAGCTGGTAC AAGAGACGGC GTACTTGGAG GATCGTCCAC TCAGCATGCT GTACTGTGCT 
CACGAGGAAA ACTGCCTTTC CAAGTCCGCT GATCACATGG ACTGGCCCTA CGGGTACCGG 
CGCTTGCTGC GCTTCTCCTC ACAGATCTAC AACCTTGGCC GGGCCGACTT CCGTCCCAAG 
GCTGGACGCC ACAGCTGGAT TTGGCACCAG TGCCACAGGC ACTACCACAG CATCGAAGTC 
TTCACTCATT ATGACCTGCT CACGCTCAAT GGCTCCAAGG TGGCCGAGGG ACACAAGGCC 
AGCTTCTGTC TAGAAGATAC AAACTGCCCC TCAGGAGTGC AGCGGCGCTA TGCATGTGCC 
AACTTTGGGG AACAGGGAGT GGCTGTAGGC TGCTGGGACA CCTACCGGCA TGACATCGAT 
TGCCAGTGGG TGGATATCAC AGATGTGGGT CCAGGGGACT ATATCTTCCA GGTGGTTGTG 
AACCCCACAA ACGATGTTGC AGAGTCCGAT TTCTCCAATA ACATGATACG GTGCCGCTGC 
AAGTATGATG GACAGCGAGT CTGGTTGCAC AACTGCCACA CAGGAGATTC CTACCGAGCC 
AATGCAGAGC TCTCCCTGGA GCAGGAACAG CGACTCAGGA ACAACTTGAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Loxl4 ( NM_001164311.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157783.1 Mus musculus lysyl oxidase-like 4 (Loxl4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu09737
Clone ID Related Accession (Same CDS sequence)	NM_001164311.1
Accession Version	NM_001164311.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	lysyl oxidase homolog 4 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124552.3, BY145829.1, AK014331.1 and BC053925.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTGGC CCCAACCACC CACCTTCTCC CTGTTCCTGC TACTGCTGCT AAGCCAAGCC 
CCTTCCAGCA GGCCACAGTC ATCAGGCACC AAGAAGCTCA GGCTTGTGGG GCCAACGGAC 
AGACCAGAGG AGGGCCGCTT GGAGGTGCTG CACCAGGGCC AGTGGGGCAC GGTGTGTGAT 
GATGACTTCG CTCTCCAGGA GGCTACTGTG GCCTGCCGAC AGCTGGGCTT TGAGTCAGCC 
TTGACCTGGG CACACAGTGC CAAGTATGGT CAAGGAGAGG GTCCCATCTG GCTGGACAAT 
GTTCGTTGTT TGGGCACCGA GAAGACCCTA GATCAGTGTG GCTCTAACGG CTGGGGTGTC 
AGTGACTGCA GACACTCAGA AGATGTTGGG GTGGTATGTC ACCCACGGCG CCAGCACGGA 
TATCACTCTG AGAAGGTCTC CAATGCCCTC GGGCCTCAGG GCCGGCGGCT AGAAGAGGTA 
CGGCTGAAAC CCATCCTCGC CAGTGCCAAA AGGCACAGCC CAGTGACTGA GGGGGCTGTG 
GAAGTACGGT ACGACGGCCA CTGGAGGCAG GTGTGTGACC AGGGCTGGAC CATGAACAAC 
AGCAGGGTTG TATGCGGGAT GCTGGGCTTT CCCAGTCAGA CATCTGTCAA CAGCCACTAC 
TACAGAAAAG TCTGGAATCT GAAGATGAAG GATCCCAAGT CTAGGCTCAA CAGCCTGACA 
AAAAAGAATT CCTTCTGGAT TCACCGGGTT GACTGTCTGG GGACAGAGCC CCACTTGGCC 
AAGTGCCAGG TACAGGTGGC TCCAGGAAGG GGCAAGCTTC GGCCAGCCTG TCCAGGCGGC 
ATGCACGCTG TGGTCAGCTG TGTGGCAGGG CCCCACTTCC GCCGACAGAA GCCAAAGCCG 
ACGCGCAAGG AGTCCCATGC AGAGCAGGAG CTGAAAGTGC GCCTGCGCTC TGGGGCTCAG 
GTGGGTGAGG GCCGTGTGGA AGTGCTCATG AACCGCCAGT GGGGCACAGT CTGTGACCAC 
AGGTGGAACC TCATCTCAGC CAGCGTCGTG TGTCGCCAGC TTGGCTTTGG CTCTGCCCGG 
GAGGCCCTTT TTGGGGCCCA GTTGGGTCAA GGGCTAGGAC CCATCCACCT GAGTGAGGTG 
CGCTGCCGGG GGTATGAGCG GACCCTGGGT GACTGCCTTG CCCTGGAAGG GTCCCAGAAT 
GGTTGTCAAC ATGCAAACGA CGCTGCTGTC AGGTGCAACA TCCCAGACAT GGGCTTCCAG 
AACAAGGTGC GCTTGGCTGG TGGGCGCAAC TCCGAAGAGG GAGTGGTGGA GGTGCAGGTG 
GAGGTGAATG GGGTCCCACG ATGGGGGACT GTATGCAGTG ACCACTGGGG GCTCACCGAA 
GCCATGGTGA CCTGTCGGCA ACTTGGTCTG GGATTTGCCA ACTTTGCTCT CAAGGACACC 
TGGTACTGGC AGGGGACACC AGAGGCCAAA GAAGTGGTGA TGAGTGGAGT TCGCTGCTCA 
GGCACAGAAA TGGCCCTGCA GCAGTGTCAG AGACATGGGC CCGTGCACTG TTCCCACGGC 
CCAGGGCGCT TCTCGGCTGG CGTTGCCTGT ATGAACAGTG CTCCAGACCT CGTGATGAAC 
GCCCAGCTGG TACAAGAGAC GGCGTACTTG GAGGATCGTC CACTCAGCAT GCTGTACTGT 
GCTCACGAGG AAAACTGCCT TTCCAAGTCC GCTGATCACA TGGACTGGCC CTACGGGTAC 
CGGCGCTTGC TGCGCTTCTC CTCACAGATC TACAACCTTG GCCGGGCCGA CTTCCGTCCC 
AAGGCTGGAC GCCACAGCTG GATTTGGCAC CAGTGCCACA GGCACTACCA CAGCATCGAA 
GTCTTCACTC ATTATGACCT GCTCACGCTC AATGGCTCCA AGGTGGCCGA GGGACACAAG 
GCCAGCTTCT GTCTAGAAGA TACAAACTGC CCCTCAGGAG TGCAGCGGCG CTATGCATGT 
GCCAACTTTG GGGAACAGGG AGTGGCTGTA GGCTGCTGGG ACACCTACCG GCATGACATC 
GATTGCCAGT GGGTGGATAT CACAGATGTG GGTCCAGGGG ACTATATCTT CCAGGTGGTT 
GTGAACCCCA CAAACGATGT TGCAGAGTCC GATTTCTCCA ATAACATGAT ACGGTGCCGC 
TGCAAGTATG ATGGACAGCG AGTCTGGTTG CACAACTGCC ACACAGGAGA TTCCTACCGA 
GCCAATGCAG AGCTCTCCCT GGAGCAGGAA CAGCGACTCA GGAACAACTT GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157783.1
CDS	106..2382
Translation	MMWPQPPTFSLFLLLLLSQAPSSRPQSSGTKKLRLVGPTDRPEEGRLEVLHQGQWGTVCDDDFALQEATVACRQLGFESALTWAHSAKYGQGEGPIWLDNVRCLGTEKTLDQCGSNGWGVSDCRHSEDVGVVCHPRRQHGYHSEKVSNALGPQGRRLEEVRLKPILASAKRHSPVTEGAVEVRYDGHWRQVCDQGWTMNNSRVVCGMLGFPSQTSVNSHYYRKVWNLKMKDPKSRLNSLTKKNSFWIHRVDCLGTEPHLAKCQVQVAPGRGKLRPACPGGMHAVVSCVAGPHFRRQKPKPTRKESHAEQELKVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGAQLGQGLGPIHLSEVRCRGYERTLGDCLALEGSQNGCQHANDAAVRCNIPDMGFQNKVRLAGGRNSEEGVVEVQVEVNGVPRWGTVCSDHWGLTEAMVTCRQLGLGFANFALKDTWYWQGTPEAKEVVMSGVRCSGTEMALQQCQRHGPVHCSHGPGRFSAGVACMNSAPDLVMNAQLVQETAYLEDRPLSMLYCAHEENCLSKSADHMDWPYGYRRLLRFSSQIYNLGRADFRPKAGRHSWIWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPSGVQRRYACANFGEQGVAVGCWDTYRHDIDCQWVDITDVGPGDYIFQVVVNPTNDVAESDFSNNMIRCRCKYDGQRVWLHNCHTGDSYRANAELSLEQEQRLRNNLI

Target ORF information:

RefSeq Version	NM_001164311.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysyl oxidase-like 4 (Loxl4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164311.1

ORF Insert Sequence:

ATGATGTGGC CCCAACCACC CACCTTCTCC CTGTTCCTGC TACTGCTGCT AAGCCAAGCC 
CCTTCCAGCA GGCCACAGTC ATCAGGCACC AAGAAGCTCA GGCTTGTGGG GCCAACGGAC 
AGACCAGAGG AGGGCCGCTT GGAGGTGCTG CACCAGGGCC AGTGGGGCAC GGTGTGTGAT 
GATGACTTCG CTCTCCAGGA GGCTACTGTG GCCTGCCGAC AGCTGGGCTT TGAGTCAGCC 
TTGACCTGGG CACACAGTGC CAAGTATGGT CAAGGAGAGG GTCCCATCTG GCTGGACAAT 
GTTCGTTGTT TGGGCACCGA GAAGACCCTA GATCAGTGTG GCTCTAACGG CTGGGGTGTC 
AGTGACTGCA GACACTCAGA AGATGTTGGG GTGGTATGTC ACCCACGGCG CCAGCACGGA 
TATCACTCTG AGAAGGTCTC CAATGCCCTC GGGCCTCAGG GCCGGCGGCT AGAAGAGGTA 
CGGCTGAAAC CCATCCTCGC CAGTGCCAAA AGGCACAGCC CAGTGACTGA GGGGGCTGTG 
GAAGTACGGT ACGACGGCCA CTGGAGGCAG GTGTGTGACC AGGGCTGGAC CATGAACAAC 
AGCAGGGTTG TATGCGGGAT GCTGGGCTTT CCCAGTCAGA CATCTGTCAA CAGCCACTAC 
TACAGAAAAG TCTGGAATCT GAAGATGAAG GATCCCAAGT CTAGGCTCAA CAGCCTGACA 
AAAAAGAATT CCTTCTGGAT TCACCGGGTT GACTGTCTGG GGACAGAGCC CCACTTGGCC 
AAGTGCCAGG TACAGGTGGC TCCAGGAAGG GGCAAGCTTC GGCCAGCCTG TCCAGGCGGC 
ATGCACGCTG TGGTCAGCTG TGTGGCAGGG CCCCACTTCC GCCGACAGAA GCCAAAGCCG 
ACGCGCAAGG AGTCCCATGC AGAGCAGGAG CTGAAAGTGC GCCTGCGCTC TGGGGCTCAG 
GTGGGTGAGG GCCGTGTGGA AGTGCTCATG AACCGCCAGT GGGGCACAGT CTGTGACCAC 
AGGTGGAACC TCATCTCAGC CAGCGTCGTG TGTCGCCAGC TTGGCTTTGG CTCTGCCCGG 
GAGGCCCTTT TTGGGGCCCA GTTGGGTCAA GGGCTAGGAC CCATCCACCT GAGTGAGGTG 
CGCTGCCGGG GGTATGAGCG GACCCTGGGT GACTGCCTTG CCCTGGAAGG GTCCCAGAAT 
GGTTGTCAAC ATGCAAACGA CGCTGCTGTC AGGTGCAACA TCCCAGACAT GGGCTTCCAG 
AACAAGGTGC GCTTGGCTGG TGGGCGCAAC TCCGAAGAGG GAGTGGTGGA GGTGCAGGTG 
GAGGTGAATG GGGTCCCACG ATGGGGGACT GTATGCAGTG ACCACTGGGG GCTCACCGAA 
GCCATGGTGA CCTGTCGGCA ACTTGGTCTG GGATTTGCCA ACTTTGCTCT CAAGGACACC 
TGGTACTGGC AGGGGACACC AGAGGCCAAA GAAGTGGTGA TGAGTGGAGT TCGCTGCTCA 
GGCACAGAAA TGGCCCTGCA GCAGTGTCAG AGACATGGGC CCGTGCACTG TTCCCACGGC 
CCAGGGCGCT TCTCGGCTGG CGTTGCCTGT ATGAACAGTG CTCCAGACCT CGTGATGAAC 
GCCCAGCTGG TACAAGAGAC GGCGTACTTG GAGGATCGTC CACTCAGCAT GCTGTACTGT 
GCTCACGAGG AAAACTGCCT TTCCAAGTCC GCTGATCACA TGGACTGGCC CTACGGGTAC 
CGGCGCTTGC TGCGCTTCTC CTCACAGATC TACAACCTTG GCCGGGCCGA CTTCCGTCCC 
AAGGCTGGAC GCCACAGCTG GATTTGGCAC CAGTGCCACA GGCACTACCA CAGCATCGAA 
GTCTTCACTC ATTATGACCT GCTCACGCTC AATGGCTCCA AGGTGGCCGA GGGACACAAG 
GCCAGCTTCT GTCTAGAAGA TACAAACTGC CCCTCAGGAG TGCAGCGGCG CTATGCATGT 
GCCAACTTTG GGGAACAGGG AGTGGCTGTA GGCTGCTGGG ACACCTACCG GCATGACATC 
GATTGCCAGT GGGTGGATAT CACAGATGTG GGTCCAGGGG ACTATATCTT CCAGGTGGTT 
GTGAACCCCA CAAACGATGT TGCAGAGTCC GATTTCTCCA ATAACATGAT ACGGTGCCGC 
TGCAAGTATG ATGGACAGCG AGTCTGGTTG CACAACTGCC ACACAGGAGA TTCCTACCGA 
GCCAATGCAG AGCTCTCCCT GGAGCAGGAA CAGCGACTCA GGAACAACTT GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer.
Oncotarget8(7)11977-11989(2017 Feb)
Choi SK,Kim HS,Jin T,Moon WK

Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.
Scientific reports633856(2016 Sep)
Zhang J,Liu Z,Zhang T,Lin Z,Li Z,Zhang A,Sun X,Gao J

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.
Calcified tissue international85(2)119-26(2009 Aug)
Pischon N,M?ki JM,Weisshaupt P,Heng N,Palamakumbura AH,N'Guessan P,Ding A,Radlanski R,Renz H,Bronckers TA,Myllyharju J,Kielbassa AM,Kleber BM,Bernimoulin JP,Trackman PC

Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage.
The Journal of biological chemistry276(26)24023-9(2001 Jun)
Ito H,Akiyama H,Iguchi H,Iyama K,Miyamoto M,Ohsawa K,Nakamura T

REQUEST A QUOTE

EMAIL

[email protected]

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Loxl4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM

SUPPORT

COMPANY

SUPPORT

COMPANY