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Home » Gene Synthesis & Molecular Biology Services » ORF » Hot Human pathways » Cytokine-cytokine receptor interaction

Overview

Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.

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Gene Symbol Full Name
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
AMH anti-Mullerian hormone
AMHR2 anti-Mullerian hormone receptor, type II
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
CXCR5 chemokine (C-X-C motif) receptor 5
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CD27 CD27 molecule
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD70 CD70 molecule
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CNTF ciliary neurotrophic factor
CNTFR ciliary neurotrophic factor receptor
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTF1 cardiotrophin 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
EDA ectodysplasin A
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPO erythropoietin
EPOR erythropoietin receptor
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
GH1 growth hormone 1
GH2 growth hormone 2
GHR growth hormone receptor
CCR10 chemokine (C-C motif) receptor 10
XCR1 chemokine (C motif) receptor 1
CXCR3 chemokine (C-X-C motif) receptor 3
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IFNA1 interferon, alpha 1
IFNA2 interferon, alpha 2
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNA10 interferon, alpha 10
IFNA13 interferon, alpha 13
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA21 interferon, alpha 21
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFNW1 interferon, omega 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RAP interleukin 1 receptor accessory protein
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL3 interleukin 3
IL3RA interleukin 3 receptor, alpha (low affinity)
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1

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