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TNFRSF8 cDNA ORF clone, Homo sapiens (human)

Gene Symbol TNFRSF8
Entrez Gene ID 943
Full Name tumor necrosis factor receptor superfamily, member 8
Synonyms CD30, D1S166E, Ki-1
General protein information
Preferred Names
tumor necrosis factor receptor superfamily member 8
Names
tumor necrosis factor receptor superfamily member 8
Ki-1 antigen
CD30L receptor
cytokine receptor CD30
lymphocyte activation antigen CD30
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36

Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

153243


mRNA and Protein(s)

mRNA Protein Name
NM_001281430 NP_001268359 tumor necrosis factor receptor superfamily member 8 isoform 3
XM_011542441 XP_011540743 tumor necrosis factor receptor superfamily member 8 isoform X1
XM_011542442 XP_011540744 tumor necrosis factor receptor superfamily member 8 isoform X2
XM_011542443 XP_011540745 tumor necrosis factor receptor superfamily member 8 isoform X3
XM_011542444 XP_011540746 tumor necrosis factor receptor superfamily member 8 isoform X2
NM_001243 NP_001234 tumor necrosis factor receptor superfamily member 8 isoform 1 precursor



Homo sapiens (human) TNFRSF8 NP_001234.2
Pan troglodytes (chimpanzee) TNFRSF8 XP_514397.3
Macaca mulatta (Rhesus monkey) TNFRSF8 XP_001118873.2
Canis lupus familiaris (dog) TNFRSF8 XP_005618040.1
Bos taurus (cattle) TNFRSF8 XP_002694100.2
Mus musculus (house mouse) Tnfrsf8 NP_033427.1
Rattus norvegicus (Norway rat) Tnfrsf8 NP_062008.1
Gallus gallus (chicken) TNFRSF8 NP_989775.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TNFRSF8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNFRSF8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu15075 NM_001281430 Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu56718 XM_011542441 PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu56719 XM_011542442 PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
OHu56720 XM_011542443 PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
OHu56719 XM_011542444 PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
OHu27899
NM_001243 Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu15075
Clone ID Related Accession (Same CDS sequence) NM_001281430
Accession Version NM_001281430.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1452bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 06-APR-2014
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 8 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M83554.1, AL357835.11, BC136400.1 and BC141804.1. On Mar 25, 2014 this sequence version replaced gi:526479842. Transcript Variant: This variant (3) has multiple differences, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant 1. The encoded protein (isoform 3) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC136400.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGTTCTGTT CCACGTCTGC CGTCAACTCC TGTGCCCGCT GCTTCTTCCA TTCTGTCTGT 
CCGGCAGGGA TGATTGTCAA GTTCCCAGGC ACGGCGCAGA AGAACACGGT CTGTGAGCCG
GCTTCCCCAG GGGTCAGCCC TGCCTGTGCC AGCCCAGAGA ACTGCAAGGA ACCCTCCAGT
GGCACCATCC CCCAGGCCAA GCCCACCCCG GTGTCCCCAG CAACCTCCAG TGCCAGCACC
ATGCCTGTAA GAGGGGGCAC CCGCCTCGCC CAGGAAGCTG CTTCTAAACT GACGAGGGCT
CCCGACTCTC CCTCCTCTGT GGGAAGGCCT AGTTCAGATC CAGGTCTGTC CCCAACACAG
CCATGCCCAG AGGGGTCTGG TGATTGCAGA AAGCAGTGTG AGCCCGACTA CTACCTGGAC
GAGGCCGGCC GCTGCACGGC CTGCGTGAGC TGTTCTCGAG ATGACCTTGT GGAGAAGACG
CCATGTGCAT GGAACTCCTC CCGCACCTGC GAATGTCGAC CTGGCATGAT CTGTGCCACA
TCAGCCACCA ACTCCTGTGC CCGCTGTGTC CCCTACCCAA TCTGTGCAGC AGAGACGGTC
ACCAAGCCCC AGGATATGGC TGAGAAGGAC ACCACCTTTG AGGCGCCACC CCTGGGGACC
CAGCCGGACT GCAACCCCAC CCCAGAGAAT GGCGAGGCGC CTGCCAGCAC CAGCCCCACT
CAGAGCTTGC TGGTGGACTC CCAGGCCAGT AAGACGCTGC CCATCCCAAC CAGCGCTCCC
GTCGCTCTCT CCTCCACGGG GAAGCCCGTT CTGGATGCAG GGCCAGTGCT CTTCTGGGTG
ATCCTGGTGT TGGTTGTGGT GGTCGGCTCC AGCGCCTTCC TCCTGTGCCA CCGGAGGGCC
TGCAGGAAGC GAATTCGGCA GAAGCTCCAC CTGTGCTACC CGGTCCAGAC CTCCCAGCCC
AAGCTAGAGC TTGTGGATTC CAGACCCAGG AGGAGCTCAA CGCTGAGGAG TGGTGCGTCG
GTGACAGAAC CCGTCGCGGA AGAGCGAGGG TTAATGAGCC AGCCACTGAT GGAGACCTGC
CACAGCGTGG GGGCAGCCTA CCTGGAGAGC CTGCCGCTGC AGGATGCCAG CCCGGCCGGG
GGCCCCTCGT CCCCCAGGGA CCTTCCTGAG CCCCGGGTGT CCACGGAGCA CACCAATAAC
AAGATTGAGA AAATCTACAT CATGAAGGCT GACACCGTGA TCGTGGGGAC CGTGAAGGCT
GAGCTGCCGG AGGGCCGGGG CCTGGCGGGG CCAGCAGAGC CCGAGTTGGA GGAGGAGCTG
GAGGCGGACC ATACCCCCCA CTACCCCGAG CAGGAGACAG AACCGCCTCT GGGCAGCTGC
AGCGATGTCA TGCTCTCAGT GGAAGAGGAA GGGAAAGAAG ACCCCTTGCC CACAGCTGCC
TCTGGAAAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001268359.2
CDS468..1919
Misc Feature(1)129..131(+)
Misc Feature(2)468..527(+)
Misc Feature(3)507..638(+)
Misc Feature(4)651..1052(+)
Misc Feature(5)744..854(+)
Misc Feature(6)861..977(+)
Misc Feature(7)981..1052(+)
Exon (1)1..285
Gene:TNFRSF8
Gene Synonym:
Exon (2)286..402
Gene:TNFRSF8
Gene Synonym:
Exon (3)403..555
Gene:TNFRSF8
Gene Synonym:
Exon (4)556..646
Gene:TNFRSF8
Gene Synonym:
Exon (5)647..810
Gene:TNFRSF8
Gene Synonym:
Exon (6)811..927
Gene:TNFRSF8
Gene Synonym:
Exon (7)928..1080
Gene:TNFRSF8
Gene Synonym:
Exon (8)1081..1174
Gene:TNFRSF8
Gene Synonym:
Exon (9)1175..1287
Gene:TNFRSF8
Gene Synonym:
Exon (10)1288..1389
Gene:TNFRSF8
Gene Synonym:
Exon (11)1390..1443
Gene:TNFRSF8
Gene Synonym:
Exon (12)1444..1469
Gene:TNFRSF8
Gene Synonym:
Exon (13)1470..1674
Gene:TNFRSF8
Gene Synonym:
Exon (14)1675..3595
Gene:TNFRSF8
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001281430
Organism Homo sapiens (human)
Definition Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001281430

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGTTCTGTT CCACGTCTGC CGTCAACTCC TGTGCCCGCT GCTTCTTCCA TTCTGTCTGT 
CCGGCAGGGA TGATTGTCAA GTTCCCAGGC ACGGCGCAGA AGAACACGGT CTGTGAGCCG
GCTTCCCCAG GGGTCAGCCC TGCCTGTGCC AGCCCAGAGA ACTGCAAGGA ACCCTCCAGT
GGCACCATCC CCCAGGCCAA GCCCACCCCG GTGTCCCCAG CAACCTCCAG TGCCAGCACC
ATGCCTGTAA GAGGGGGCAC CCGCCTCGCC CAGGAAGCTG CTTCTAAACT GACGAGGGCT
CCCGACTCTC CCTCCTCTGT GGGAAGGCCT AGTTCAGATC CAGGTCTGTC CCCAACACAG
CCATGCCCAG AGGGGTCTGG TGATTGCAGA AAGCAGTGTG AGCCCGACTA CTACCTGGAC
GAGGCCGGCC GCTGCACGGC CTGCGTGAGC TGTTCTCGAG ATGACCTTGT GGAGAAGACG
CCATGTGCAT GGAACTCCTC CCGCACCTGC GAATGTCGAC CTGGCATGAT CTGTGCCACA
TCAGCCACCA ACTCCTGTGC CCGCTGTGTC CCCTACCCAA TCTGTGCAGC AGAGACGGTC
ACCAAGCCCC AGGATATGGC TGAGAAGGAC ACCACCTTTG AGGCGCCACC CCTGGGGACC
CAGCCGGACT GCAACCCCAC CCCAGAGAAT GGCGAGGCGC CTGCCAGCAC CAGCCCCACT
CAGAGCTTGC TGGTGGACTC CCAGGCCAGT AAGACGCTGC CCATCCCAAC CAGCGCTCCC
GTCGCTCTCT CCTCCACGGG GAAGCCCGTT CTGGATGCAG GGCCAGTGCT CTTCTGGGTG
ATCCTGGTGT TGGTTGTGGT GGTCGGCTCC AGCGCCTTCC TCCTGTGCCA CCGGAGGGCC
TGCAGGAAGC GAATTCGGCA GAAGCTCCAC CTGTGCTACC CGGTCCAGAC CTCCCAGCCC
AAGCTAGAGC TTGTGGATTC CAGACCCAGG AGGAGCTCAA CGCTGAGGAG TGGTGCGTCG
GTGACAGAAC CCGTCGCGGA AGAGCGAGGG TTAATGAGCC AGCCACTGAT GGAGACCTGC
CACAGCGTGG GGGCAGCCTA CCTGGAGAGC CTGCCGCTGC AGGATGCCAG CCCGGCCGGG
GGCCCCTCGT CCCCCAGGGA CCTTCCTGAG CCCCGGGTGT CCACGGAGCA CACCAATAAC
AAGATTGAGA AAATCTACAT CATGAAGGCT GACACCGTGA TCGTGGGGAC CGTGAAGGCT
GAGCTGCCGG AGGGCCGGGG CCTGGCGGGG CCAGCAGAGC CCGAGTTGGA GGAGGAGCTG
GAGGCGGACC ATACCCCCCA CTACCCCGAG CAGGAGACAG AACCGCCTCT GGGCAGCTGC
AGCGATGTCA TGCTCTCAGT GGAAGAGGAA GGGAAAGAAG ACCCCTTGCC CACAGCTGCC
TCTGGAAAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu56718
Clone ID Related Accession (Same CDS sequence) XM_011542441
Accession Version XM_011542441.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1785bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 8 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGCGCGTCC TCCTCGCCGC GCTGGGACTG CTGTTCCTGG GGGCGCTACG AGCCTTCCCA 
CAGGATCGAC CCTTCGAGGA CACCTGTCAT GGAAACCCCA GCCACTACTA TGACAAGGCT
GTCAGGAGGT GCTGTTACCG CTGCCCCATG GGGCTGTTCC CGACACAGCA GTGCCCACAG
AGGCCTACTG ACTGCAGGAA GCAGTGTGAG CCTGACTACT ACCTGGATGA GGCCGACCGC
TGTACAGCCT GCGTGACTTG TTCTCGAGAC GACCTCGTGG AGAAGACGCC GTGTGCATGG
AACTCCTCCC GTGTCTGCGA ATGTCGACCC GGCATGTTCT GTTCCACGTC TGCCGTCAAC
TCCTGTGCCC GCTGCTTCTT CCATTCTGTC TGTCCGGCAG GGATGATTGT CAAGTTCCCA
GGCACGGCGC AGAAGAACAC GGTCTGTGAG CCGGCTTCCC CAGGGGTCAG CCCTGCCTGT
GCCAGCCCAG AGAACTGCAA GGAACCCTCC AGTGGCACCA TCCCCCAGGC CAAGCCCACC
CCGGTGTCCC CAGCAACCTC CAGTGCCAGC ACCATGCCTG TAAGAGGGGG CACCCGCCTC
GCCCAGGAAG CTGCTTCTAA ACTGACGAGG GCTCCCGACT CTCCCTCCTC TGTGGGAAGG
CCTAGTTCAG ATCCAGGTCT GTCCCCAACA CAGCCATGCC CAGAGGGGTC TGGTGATTGC
AGAAAGCAGT GTGAGCCCGA CTACTACCTG GACGAGGCCG GCCGCTGCAC GGCCTGCGTG
AGCTGTTCTC GAGATGACCT TGTGGAGAAG ACGCCATGTG CATGGAACTC CTCCCGCACC
TGCGAATGTC GACCTGGCAT GATCTGTGCC ACATCAGCCA CCAACTCCTG TGCCCGCTGT
GTCCCCTACC CAATCTGTGC AGCAGAGACG GTCACCAAGC CCCAGGATAT GGCTGAGAAG
GACACCACCT TTGAGGCGCC ACCCCTGGGG ACCCAGCCGG ACTGCAACCC CACCCCAGAG
AATGGCGAGG CGCCTGCCAG CACCAGCCCC ACTCAGAGCT TGCTGGTGGA CTCCCAGGCC
AGTAAGACGC TGCCCATCCC AACCAGCGCT CCCGTCGCTC TCTCCTCCAC GGGGAAGCCC
GTTCTGGATG CAGGGCCAGT GCTCTTCTGG GTGATCCTGG TGTTGGTTGT GGTGGTCGGC
TCCAGCGCCT TCCTCCTGTG CCACCGGAGG GCCTGCAGGA AGCGAATTCG GCAGAAGCTC
CACCTGTGCT ACCCGGTCCA GACCTCCCAG CCCAAGCTAG AGCTTGTGGA TTCCAGACCC
AGGAGGAGCT CAACGCTGAG GAGTGGTGCG TCGGTGACAG AACCCGTCGC GGAAGAGCGA
GGGTTAATGA GCCAGCCACT GATGGAGACC TGCCACAGCG TGGGGGCAGC CTACCTGGAG
AGCCTGCCGC TGCAGGATGC CAGCCCGGCC GGGGGCCCCT CGTCCCCCAG GGACCTTCCT
GAGCCCCGGG TGTCCACGGA GCACACCAAT AACAAGATTG AGAAAATCTA CATCATGAAG
GCTGACACCG TGATCGTGGG GACCGTGAAG GCTGAGCTGC CGGAGGGCCG GGGCCTGGCG
GGGCCAGCAG AGCCCGAGTT GGAGGAGGAG CTGGAGGCGG ACCATACCCC CCACTACCCC
GAGCAGGAGA CAGAACCGCC TCTGGGCAGC TGCAGCGATG TCATGCTCTC AGTGGAAGAG
GAAGGGAAAG AAGACCCCTT GCCCACAGCT GCCTCTGGAA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011540743.1
CDS270..2054
Misc Feature(1)318..662(+)
Misc Feature(2)354..464(+)
Misc Feature(3)471..587(+)
Misc Feature(4)591..662(+)
Misc Feature(5)786..1187(+)
Misc Feature(6)879..989(+)
Misc Feature(7)996..1112(+)
Misc Feature(8)1116..1187(+)
Translation

Target ORF information:

RefSeq Version XM_011542441
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011542441

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGCGCGTCC TCCTCGCCGC GCTGGGACTG CTGTTCCTGG GGGCGCTACG AGCCTTCCCA 
CAGGATCGAC CCTTCGAGGA CACCTGTCAT GGAAACCCCA GCCACTACTA TGACAAGGCT
GTCAGGAGGT GCTGTTACCG CTGCCCCATG GGGCTGTTCC CGACACAGCA GTGCCCACAG
AGGCCTACTG ACTGCAGGAA GCAGTGTGAG CCTGACTACT ACCTGGATGA GGCCGACCGC
TGTACAGCCT GCGTGACTTG TTCTCGAGAC GACCTCGTGG AGAAGACGCC GTGTGCATGG
AACTCCTCCC GTGTCTGCGA ATGTCGACCC GGCATGTTCT GTTCCACGTC TGCCGTCAAC
TCCTGTGCCC GCTGCTTCTT CCATTCTGTC TGTCCGGCAG GGATGATTGT CAAGTTCCCA
GGCACGGCGC AGAAGAACAC GGTCTGTGAG CCGGCTTCCC CAGGGGTCAG CCCTGCCTGT
GCCAGCCCAG AGAACTGCAA GGAACCCTCC AGTGGCACCA TCCCCCAGGC CAAGCCCACC
CCGGTGTCCC CAGCAACCTC CAGTGCCAGC ACCATGCCTG TAAGAGGGGG CACCCGCCTC
GCCCAGGAAG CTGCTTCTAA ACTGACGAGG GCTCCCGACT CTCCCTCCTC TGTGGGAAGG
CCTAGTTCAG ATCCAGGTCT GTCCCCAACA CAGCCATGCC CAGAGGGGTC TGGTGATTGC
AGAAAGCAGT GTGAGCCCGA CTACTACCTG GACGAGGCCG GCCGCTGCAC GGCCTGCGTG
AGCTGTTCTC GAGATGACCT TGTGGAGAAG ACGCCATGTG CATGGAACTC CTCCCGCACC
TGCGAATGTC GACCTGGCAT GATCTGTGCC ACATCAGCCA CCAACTCCTG TGCCCGCTGT
GTCCCCTACC CAATCTGTGC AGCAGAGACG GTCACCAAGC CCCAGGATAT GGCTGAGAAG
GACACCACCT TTGAGGCGCC ACCCCTGGGG ACCCAGCCGG ACTGCAACCC CACCCCAGAG
AATGGCGAGG CGCCTGCCAG CACCAGCCCC ACTCAGAGCT TGCTGGTGGA CTCCCAGGCC
AGTAAGACGC TGCCCATCCC AACCAGCGCT CCCGTCGCTC TCTCCTCCAC GGGGAAGCCC
GTTCTGGATG CAGGGCCAGT GCTCTTCTGG GTGATCCTGG TGTTGGTTGT GGTGGTCGGC
TCCAGCGCCT TCCTCCTGTG CCACCGGAGG GCCTGCAGGA AGCGAATTCG GCAGAAGCTC
CACCTGTGCT ACCCGGTCCA GACCTCCCAG CCCAAGCTAG AGCTTGTGGA TTCCAGACCC
AGGAGGAGCT CAACGCTGAG GAGTGGTGCG TCGGTGACAG AACCCGTCGC GGAAGAGCGA
GGGTTAATGA GCCAGCCACT GATGGAGACC TGCCACAGCG TGGGGGCAGC CTACCTGGAG
AGCCTGCCGC TGCAGGATGC CAGCCCGGCC GGGGGCCCCT CGTCCCCCAG GGACCTTCCT
GAGCCCCGGG TGTCCACGGA GCACACCAAT AACAAGATTG AGAAAATCTA CATCATGAAG
GCTGACACCG TGATCGTGGG GACCGTGAAG GCTGAGCTGC CGGAGGGCCG GGGCCTGGCG
GGGCCAGCAG AGCCCGAGTT GGAGGAGGAG CTGGAGGCGG ACCATACCCC CCACTACCCC
GAGCAGGAGA CAGAACCGCC TCTGGGCAGC TGCAGCGATG TCATGCTCTC AGTGGAAGAG
GAAGGGAAAG AAGACCCCTT GCCCACAGCT GCCTCTGGAA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu56719
Clone ID Related Accession (Same CDS sequence) XM_011542442 , XM_011542444
Accession Version XM_011542442.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1641bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 8 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGGGCTGT TCCCGACACA GCAGTGCCCA CAGAGGCCTA CTGACTGCAG GAAGCAGTGT 
GAGCCTGACT ACTACCTGGA TGAGGCCGAC CGCTGTACAG CCTGCGTGAC TTGTTCTCGA
GACGACCTCG TGGAGAAGAC GCCGTGTGCA TGGAACTCCT CCCGTGTCTG CGAATGTCGA
CCCGGCATGT TCTGTTCCAC GTCTGCCGTC AACTCCTGTG CCCGCTGCTT CTTCCATTCT
GTCTGTCCGG CAGGGATGAT TGTCAAGTTC CCAGGCACGG CGCAGAAGAA CACGGTCTGT
GAGCCGGCTT CCCCAGGGGT CAGCCCTGCC TGTGCCAGCC CAGAGAACTG CAAGGAACCC
TCCAGTGGCA CCATCCCCCA GGCCAAGCCC ACCCCGGTGT CCCCAGCAAC CTCCAGTGCC
AGCACCATGC CTGTAAGAGG GGGCACCCGC CTCGCCCAGG AAGCTGCTTC TAAACTGACG
AGGGCTCCCG ACTCTCCCTC CTCTGTGGGA AGGCCTAGTT CAGATCCAGG TCTGTCCCCA
ACACAGCCAT GCCCAGAGGG GTCTGGTGAT TGCAGAAAGC AGTGTGAGCC CGACTACTAC
CTGGACGAGG CCGGCCGCTG CACGGCCTGC GTGAGCTGTT CTCGAGATGA CCTTGTGGAG
AAGACGCCAT GTGCATGGAA CTCCTCCCGC ACCTGCGAAT GTCGACCTGG CATGATCTGT
GCCACATCAG CCACCAACTC CTGTGCCCGC TGTGTCCCCT ACCCAATCTG TGCAGCAGAG
ACGGTCACCA AGCCCCAGGA TATGGCTGAG AAGGACACCA CCTTTGAGGC GCCACCCCTG
GGGACCCAGC CGGACTGCAA CCCCACCCCA GAGAATGGCG AGGCGCCTGC CAGCACCAGC
CCCACTCAGA GCTTGCTGGT GGACTCCCAG GCCAGTAAGA CGCTGCCCAT CCCAACCAGC
GCTCCCGTCG CTCTCTCCTC CACGGGGAAG CCCGTTCTGG ATGCAGGGCC AGTGCTCTTC
TGGGTGATCC TGGTGTTGGT TGTGGTGGTC GGCTCCAGCG CCTTCCTCCT GTGCCACCGG
AGGGCCTGCA GGAAGCGAAT TCGGCAGAAG CTCCACCTGT GCTACCCGGT CCAGACCTCC
CAGCCCAAGC TAGAGCTTGT GGATTCCAGA CCCAGGAGGA GCTCAACGCA GCTGAGGAGT
GGTGCGTCGG TGACAGAACC CGTCGCGGAA GAGCGAGGGT TAATGAGCCA GCCACTGATG
GAGACCTGCC ACAGCGTGGG GGCAGCCTAC CTGGAGAGCC TGCCGCTGCA GGATGCCAGC
CCGGCCGGGG GCCCCTCGTC CCCCAGGGAC CTTCCTGAGC CCCGGGTGTC CACGGAGCAC
ACCAATAACA AGATTGAGAA AATCTACATC ATGAAGGCTG ACACCGTGAT CGTGGGGACC
GTGAAGGCTG AGCTGCCGGA GGGCCGGGGC CTGGCGGGGC CAGCAGAGCC CGAGTTGGAG
GAGGAGCTGG AGGCGGACCA TACCCCCCAC TACCCCGAGC AGGAGACAGA ACCGCCTCTG
GGCAGCTGCA GCGATGTCAT GCTCTCAGTG GAAGAGGAAG GGAAAGAAGA CCCCTTGCCC
ACAGCTGCCT CTGGAAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011540744.1
CDS106..1746
Misc Feature(1)106..351(+)
Misc Feature(2)160..276(+)
Misc Feature(3)280..351(+)
Misc Feature(4)475..876(+)
Misc Feature(5)568..678(+)
Misc Feature(6)685..801(+)
Misc Feature(7)805..876(+)
Translation

Target ORF information:

RefSeq Version XM_011542442
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011542442

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGGGCTGT TCCCGACACA GCAGTGCCCA CAGAGGCCTA CTGACTGCAG GAAGCAGTGT 
GAGCCTGACT ACTACCTGGA TGAGGCCGAC CGCTGTACAG CCTGCGTGAC TTGTTCTCGA
GACGACCTCG TGGAGAAGAC GCCGTGTGCA TGGAACTCCT CCCGTGTCTG CGAATGTCGA
CCCGGCATGT TCTGTTCCAC GTCTGCCGTC AACTCCTGTG CCCGCTGCTT CTTCCATTCT
GTCTGTCCGG CAGGGATGAT TGTCAAGTTC CCAGGCACGG CGCAGAAGAA CACGGTCTGT
GAGCCGGCTT CCCCAGGGGT CAGCCCTGCC TGTGCCAGCC CAGAGAACTG CAAGGAACCC
TCCAGTGGCA CCATCCCCCA GGCCAAGCCC ACCCCGGTGT CCCCAGCAAC CTCCAGTGCC
AGCACCATGC CTGTAAGAGG GGGCACCCGC CTCGCCCAGG AAGCTGCTTC TAAACTGACG
AGGGCTCCCG ACTCTCCCTC CTCTGTGGGA AGGCCTAGTT CAGATCCAGG TCTGTCCCCA
ACACAGCCAT GCCCAGAGGG GTCTGGTGAT TGCAGAAAGC AGTGTGAGCC CGACTACTAC
CTGGACGAGG CCGGCCGCTG CACGGCCTGC GTGAGCTGTT CTCGAGATGA CCTTGTGGAG
AAGACGCCAT GTGCATGGAA CTCCTCCCGC ACCTGCGAAT GTCGACCTGG CATGATCTGT
GCCACATCAG CCACCAACTC CTGTGCCCGC TGTGTCCCCT ACCCAATCTG TGCAGCAGAG
ACGGTCACCA AGCCCCAGGA TATGGCTGAG AAGGACACCA CCTTTGAGGC GCCACCCCTG
GGGACCCAGC CGGACTGCAA CCCCACCCCA GAGAATGGCG AGGCGCCTGC CAGCACCAGC
CCCACTCAGA GCTTGCTGGT GGACTCCCAG GCCAGTAAGA CGCTGCCCAT CCCAACCAGC
GCTCCCGTCG CTCTCTCCTC CACGGGGAAG CCCGTTCTGG ATGCAGGGCC AGTGCTCTTC
TGGGTGATCC TGGTGTTGGT TGTGGTGGTC GGCTCCAGCG CCTTCCTCCT GTGCCACCGG
AGGGCCTGCA GGAAGCGAAT TCGGCAGAAG CTCCACCTGT GCTACCCGGT CCAGACCTCC
CAGCCCAAGC TAGAGCTTGT GGATTCCAGA CCCAGGAGGA GCTCAACGCA GCTGAGGAGT
GGTGCGTCGG TGACAGAACC CGTCGCGGAA GAGCGAGGGT TAATGAGCCA GCCACTGATG
GAGACCTGCC ACAGCGTGGG GGCAGCCTAC CTGGAGAGCC TGCCGCTGCA GGATGCCAGC
CCGGCCGGGG GCCCCTCGTC CCCCAGGGAC CTTCCTGAGC CCCGGGTGTC CACGGAGCAC
ACCAATAACA AGATTGAGAA AATCTACATC ATGAAGGCTG ACACCGTGAT CGTGGGGACC
GTGAAGGCTG AGCTGCCGGA GGGCCGGGGC CTGGCGGGGC CAGCAGAGCC CGAGTTGGAG
GAGGAGCTGG AGGCGGACCA TACCCCCCAC TACCCCGAGC AGGAGACAGA ACCGCCTCTG
GGCAGCTGCA GCGATGTCAT GCTCTCAGTG GAAGAGGAAG GGAAAGAAGA CCCCTTGCCC
ACAGCTGCCT CTGGAAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu56720
Clone ID Related Accession (Same CDS sequence) XM_011542443
Accession Version XM_011542443.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1455bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 8 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGTTCTGTT CCACGTCTGC CGTCAACTCC TGTGCCCGCT GCTTCTTCCA TTCTGTCTGT 
CCGGCAGGGA TGATTGTCAA GTTCCCAGGC ACGGCGCAGA AGAACACGGT CTGTGAGCCG
GCTTCCCCAG GGGTCAGCCC TGCCTGTGCC AGCCCAGAGA ACTGCAAGGA ACCCTCCAGT
GGCACCATCC CCCAGGCCAA GCCCACCCCG GTGTCCCCAG CAACCTCCAG TGCCAGCACC
ATGCCTGTAA GAGGGGGCAC CCGCCTCGCC CAGGAAGCTG CTTCTAAACT GACGAGGGCT
CCCGACTCTC CCTCCTCTGT GGGAAGGCCT AGTTCAGATC CAGGTCTGTC CCCAACACAG
CCATGCCCAG AGGGGTCTGG TGATTGCAGA AAGCAGTGTG AGCCCGACTA CTACCTGGAC
GAGGCCGGCC GCTGCACGGC CTGCGTGAGC TGTTCTCGAG ATGACCTTGT GGAGAAGACG
CCATGTGCAT GGAACTCCTC CCGCACCTGC GAATGTCGAC CTGGCATGAT CTGTGCCACA
TCAGCCACCA ACTCCTGTGC CCGCTGTGTC CCCTACCCAA TCTGTGCAGC AGAGACGGTC
ACCAAGCCCC AGGATATGGC TGAGAAGGAC ACCACCTTTG AGGCGCCACC CCTGGGGACC
CAGCCGGACT GCAACCCCAC CCCAGAGAAT GGCGAGGCGC CTGCCAGCAC CAGCCCCACT
CAGAGCTTGC TGGTGGACTC CCAGGCCAGT AAGACGCTGC CCATCCCAAC CAGCGCTCCC
GTCGCTCTCT CCTCCACGGG GAAGCCCGTT CTGGATGCAG GGCCAGTGCT CTTCTGGGTG
ATCCTGGTGT TGGTTGTGGT GGTCGGCTCC AGCGCCTTCC TCCTGTGCCA CCGGAGGGCC
TGCAGGAAGC GAATTCGGCA GAAGCTCCAC CTGTGCTACC CGGTCCAGAC CTCCCAGCCC
AAGCTAGAGC TTGTGGATTC CAGACCCAGG AGGAGCTCAA CGCAGCTGAG GAGTGGTGCG
TCGGTGACAG AACCCGTCGC GGAAGAGCGA GGGTTAATGA GCCAGCCACT GATGGAGACC
TGCCACAGCG TGGGGGCAGC CTACCTGGAG AGCCTGCCGC TGCAGGATGC CAGCCCGGCC
GGGGGCCCCT CGTCCCCCAG GGACCTTCCT GAGCCCCGGG TGTCCACGGA GCACACCAAT
AACAAGATTG AGAAAATCTA CATCATGAAG GCTGACACCG TGATCGTGGG GACCGTGAAG
GCTGAGCTGC CGGAGGGCCG GGGCCTGGCG GGGCCAGCAG AGCCCGAGTT GGAGGAGGAG
CTGGAGGCGG ACCATACCCC CCACTACCCC GAGCAGGAGA CAGAACCGCC TCTGGGCAGC
TGCAGCGATG TCATGCTCTC AGTGGAAGAG GAAGGGAAAG AAGACCCCTT GCCCACAGCT
GCCTCTGGAA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011540745.1
CDS661..2115
Misc Feature(1)661..720(+)
Misc Feature(2)700..831(+)
Misc Feature(3)844..1245(+)
Misc Feature(4)937..1047(+)
Misc Feature(5)1054..1170(+)
Misc Feature(6)1174..1245(+)
Translation

Target ORF information:

RefSeq Version XM_011542443
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011542443

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGTTCTGTT CCACGTCTGC CGTCAACTCC TGTGCCCGCT GCTTCTTCCA TTCTGTCTGT 
CCGGCAGGGA TGATTGTCAA GTTCCCAGGC ACGGCGCAGA AGAACACGGT CTGTGAGCCG
GCTTCCCCAG GGGTCAGCCC TGCCTGTGCC AGCCCAGAGA ACTGCAAGGA ACCCTCCAGT
GGCACCATCC CCCAGGCCAA GCCCACCCCG GTGTCCCCAG CAACCTCCAG TGCCAGCACC
ATGCCTGTAA GAGGGGGCAC CCGCCTCGCC CAGGAAGCTG CTTCTAAACT GACGAGGGCT
CCCGACTCTC CCTCCTCTGT GGGAAGGCCT AGTTCAGATC CAGGTCTGTC CCCAACACAG
CCATGCCCAG AGGGGTCTGG TGATTGCAGA AAGCAGTGTG AGCCCGACTA CTACCTGGAC
GAGGCCGGCC GCTGCACGGC CTGCGTGAGC TGTTCTCGAG ATGACCTTGT GGAGAAGACG
CCATGTGCAT GGAACTCCTC CCGCACCTGC GAATGTCGAC CTGGCATGAT CTGTGCCACA
TCAGCCACCA ACTCCTGTGC CCGCTGTGTC CCCTACCCAA TCTGTGCAGC AGAGACGGTC
ACCAAGCCCC AGGATATGGC TGAGAAGGAC ACCACCTTTG AGGCGCCACC CCTGGGGACC
CAGCCGGACT GCAACCCCAC CCCAGAGAAT GGCGAGGCGC CTGCCAGCAC CAGCCCCACT
CAGAGCTTGC TGGTGGACTC CCAGGCCAGT AAGACGCTGC CCATCCCAAC CAGCGCTCCC
GTCGCTCTCT CCTCCACGGG GAAGCCCGTT CTGGATGCAG GGCCAGTGCT CTTCTGGGTG
ATCCTGGTGT TGGTTGTGGT GGTCGGCTCC AGCGCCTTCC TCCTGTGCCA CCGGAGGGCC
TGCAGGAAGC GAATTCGGCA GAAGCTCCAC CTGTGCTACC CGGTCCAGAC CTCCCAGCCC
AAGCTAGAGC TTGTGGATTC CAGACCCAGG AGGAGCTCAA CGCAGCTGAG GAGTGGTGCG
TCGGTGACAG AACCCGTCGC GGAAGAGCGA GGGTTAATGA GCCAGCCACT GATGGAGACC
TGCCACAGCG TGGGGGCAGC CTACCTGGAG AGCCTGCCGC TGCAGGATGC CAGCCCGGCC
GGGGGCCCCT CGTCCCCCAG GGACCTTCCT GAGCCCCGGG TGTCCACGGA GCACACCAAT
AACAAGATTG AGAAAATCTA CATCATGAAG GCTGACACCG TGATCGTGGG GACCGTGAAG
GCTGAGCTGC CGGAGGGCCG GGGCCTGGCG GGGCCAGCAG AGCCCGAGTT GGAGGAGGAG
CTGGAGGCGG ACCATACCCC CCACTACCCC GAGCAGGAGA CAGAACCGCC TCTGGGCAGC
TGCAGCGATG TCATGCTCTC AGTGGAAGAG GAAGGGAAAG AAGACCCCTT GCCCACAGCT
GCCTCTGGAA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu56719
Clone ID Related Accession (Same CDS sequence) XM_011542442 , XM_011542444
Accession Version XM_011542444.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1641bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 8 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGGGCTGT TCCCGACACA GCAGTGCCCA CAGAGGCCTA CTGACTGCAG GAAGCAGTGT 
GAGCCTGACT ACTACCTGGA TGAGGCCGAC CGCTGTACAG CCTGCGTGAC TTGTTCTCGA
GACGACCTCG TGGAGAAGAC GCCGTGTGCA TGGAACTCCT CCCGTGTCTG CGAATGTCGA
CCCGGCATGT TCTGTTCCAC GTCTGCCGTC AACTCCTGTG CCCGCTGCTT CTTCCATTCT
GTCTGTCCGG CAGGGATGAT TGTCAAGTTC CCAGGCACGG CGCAGAAGAA CACGGTCTGT
GAGCCGGCTT CCCCAGGGGT CAGCCCTGCC TGTGCCAGCC CAGAGAACTG CAAGGAACCC
TCCAGTGGCA CCATCCCCCA GGCCAAGCCC ACCCCGGTGT CCCCAGCAAC CTCCAGTGCC
AGCACCATGC CTGTAAGAGG GGGCACCCGC CTCGCCCAGG AAGCTGCTTC TAAACTGACG
AGGGCTCCCG ACTCTCCCTC CTCTGTGGGA AGGCCTAGTT CAGATCCAGG TCTGTCCCCA
ACACAGCCAT GCCCAGAGGG GTCTGGTGAT TGCAGAAAGC AGTGTGAGCC CGACTACTAC
CTGGACGAGG CCGGCCGCTG CACGGCCTGC GTGAGCTGTT CTCGAGATGA CCTTGTGGAG
AAGACGCCAT GTGCATGGAA CTCCTCCCGC ACCTGCGAAT GTCGACCTGG CATGATCTGT
GCCACATCAG CCACCAACTC CTGTGCCCGC TGTGTCCCCT ACCCAATCTG TGCAGCAGAG
ACGGTCACCA AGCCCCAGGA TATGGCTGAG AAGGACACCA CCTTTGAGGC GCCACCCCTG
GGGACCCAGC CGGACTGCAA CCCCACCCCA GAGAATGGCG AGGCGCCTGC CAGCACCAGC
CCCACTCAGA GCTTGCTGGT GGACTCCCAG GCCAGTAAGA CGCTGCCCAT CCCAACCAGC
GCTCCCGTCG CTCTCTCCTC CACGGGGAAG CCCGTTCTGG ATGCAGGGCC AGTGCTCTTC
TGGGTGATCC TGGTGTTGGT TGTGGTGGTC GGCTCCAGCG CCTTCCTCCT GTGCCACCGG
AGGGCCTGCA GGAAGCGAAT TCGGCAGAAG CTCCACCTGT GCTACCCGGT CCAGACCTCC
CAGCCCAAGC TAGAGCTTGT GGATTCCAGA CCCAGGAGGA GCTCAACGCA GCTGAGGAGT
GGTGCGTCGG TGACAGAACC CGTCGCGGAA GAGCGAGGGT TAATGAGCCA GCCACTGATG
GAGACCTGCC ACAGCGTGGG GGCAGCCTAC CTGGAGAGCC TGCCGCTGCA GGATGCCAGC
CCGGCCGGGG GCCCCTCGTC CCCCAGGGAC CTTCCTGAGC CCCGGGTGTC CACGGAGCAC
ACCAATAACA AGATTGAGAA AATCTACATC ATGAAGGCTG ACACCGTGAT CGTGGGGACC
GTGAAGGCTG AGCTGCCGGA GGGCCGGGGC CTGGCGGGGC CAGCAGAGCC CGAGTTGGAG
GAGGAGCTGG AGGCGGACCA TACCCCCCAC TACCCCGAGC AGGAGACAGA ACCGCCTCTG
GGCAGCTGCA GCGATGTCAT GCTCTCAGTG GAAGAGGAAG GGAAAGAAGA CCCCTTGCCC
ACAGCTGCCT CTGGAAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011540746.1
CDS153..1793
Misc Feature(1)153..398(+)
Misc Feature(2)207..323(+)
Misc Feature(3)327..398(+)
Misc Feature(4)522..923(+)
Misc Feature(5)615..725(+)
Misc Feature(6)732..848(+)
Misc Feature(7)852..923(+)
Translation

Target ORF information:

RefSeq Version XM_011542444
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011542444

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGGGCTGT TCCCGACACA GCAGTGCCCA CAGAGGCCTA CTGACTGCAG GAAGCAGTGT 
GAGCCTGACT ACTACCTGGA TGAGGCCGAC CGCTGTACAG CCTGCGTGAC TTGTTCTCGA
GACGACCTCG TGGAGAAGAC GCCGTGTGCA TGGAACTCCT CCCGTGTCTG CGAATGTCGA
CCCGGCATGT TCTGTTCCAC GTCTGCCGTC AACTCCTGTG CCCGCTGCTT CTTCCATTCT
GTCTGTCCGG CAGGGATGAT TGTCAAGTTC CCAGGCACGG CGCAGAAGAA CACGGTCTGT
GAGCCGGCTT CCCCAGGGGT CAGCCCTGCC TGTGCCAGCC CAGAGAACTG CAAGGAACCC
TCCAGTGGCA CCATCCCCCA GGCCAAGCCC ACCCCGGTGT CCCCAGCAAC CTCCAGTGCC
AGCACCATGC CTGTAAGAGG GGGCACCCGC CTCGCCCAGG AAGCTGCTTC TAAACTGACG
AGGGCTCCCG ACTCTCCCTC CTCTGTGGGA AGGCCTAGTT CAGATCCAGG TCTGTCCCCA
ACACAGCCAT GCCCAGAGGG GTCTGGTGAT TGCAGAAAGC AGTGTGAGCC CGACTACTAC
CTGGACGAGG CCGGCCGCTG CACGGCCTGC GTGAGCTGTT CTCGAGATGA CCTTGTGGAG
AAGACGCCAT GTGCATGGAA CTCCTCCCGC ACCTGCGAAT GTCGACCTGG CATGATCTGT
GCCACATCAG CCACCAACTC CTGTGCCCGC TGTGTCCCCT ACCCAATCTG TGCAGCAGAG
ACGGTCACCA AGCCCCAGGA TATGGCTGAG AAGGACACCA CCTTTGAGGC GCCACCCCTG
GGGACCCAGC CGGACTGCAA CCCCACCCCA GAGAATGGCG AGGCGCCTGC CAGCACCAGC
CCCACTCAGA GCTTGCTGGT GGACTCCCAG GCCAGTAAGA CGCTGCCCAT CCCAACCAGC
GCTCCCGTCG CTCTCTCCTC CACGGGGAAG CCCGTTCTGG ATGCAGGGCC AGTGCTCTTC
TGGGTGATCC TGGTGTTGGT TGTGGTGGTC GGCTCCAGCG CCTTCCTCCT GTGCCACCGG
AGGGCCTGCA GGAAGCGAAT TCGGCAGAAG CTCCACCTGT GCTACCCGGT CCAGACCTCC
CAGCCCAAGC TAGAGCTTGT GGATTCCAGA CCCAGGAGGA GCTCAACGCA GCTGAGGAGT
GGTGCGTCGG TGACAGAACC CGTCGCGGAA GAGCGAGGGT TAATGAGCCA GCCACTGATG
GAGACCTGCC ACAGCGTGGG GGCAGCCTAC CTGGAGAGCC TGCCGCTGCA GGATGCCAGC
CCGGCCGGGG GCCCCTCGTC CCCCAGGGAC CTTCCTGAGC CCCGGGTGTC CACGGAGCAC
ACCAATAACA AGATTGAGAA AATCTACATC ATGAAGGCTG ACACCGTGAT CGTGGGGACC
GTGAAGGCTG AGCTGCCGGA GGGCCGGGGC CTGGCGGGGC CAGCAGAGCC CGAGTTGGAG
GAGGAGCTGG AGGCGGACCA TACCCCCCAC TACCCCGAGC AGGAGACAGA ACCGCCTCTG
GGCAGCTGCA GCGATGTCAT GCTCTCAGTG GAAGAGGAAG GGAAAGAAGA CCCCTTGCCC
ACAGCTGCCT CTGGAAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27899
Clone ID Related Accession (Same CDS sequence) NM_001243
Accession Version NM_001243.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1788bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 8 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M83554.1, AL357835.11, BC136400.1 and BC141804.1. This sequence is a reference standard in the RefSeqGene project. On Mar 25, 2014 this sequence version replaced gi:68348710. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M83554.1, S75768.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGCGCGTCC TCCTCGCCGC GCTGGGACTG CTGTTCCTGG GGGCGCTACG AGCCTTCCCA 
CAGGATCGAC CCTTCGAGGA CACCTGTCAT GGAAACCCCA GCCACTACTA TGACAAGGCT
GTCAGGAGGT GCTGTTACCG CTGCCCCATG GGGCTGTTCC CGACACAGCA GTGCCCACAG
AGGCCTACTG ACTGCAGGAA GCAGTGTGAG CCTGACTACT ACCTGGATGA GGCCGACCGC
TGTACAGCCT GCGTGACTTG TTCTCGAGAC GACCTCGTGG AGAAGACGCC GTGTGCATGG
AACTCCTCCC GTGTCTGCGA ATGTCGACCC GGCATGTTCT GTTCCACGTC TGCCGTCAAC
TCCTGTGCCC GCTGCTTCTT CCATTCTGTC TGTCCGGCAG GGATGATTGT CAAGTTCCCA
GGCACGGCGC AGAAGAACAC GGTCTGTGAG CCGGCTTCCC CAGGGGTCAG CCCTGCCTGT
GCCAGCCCAG AGAACTGCAA GGAACCCTCC AGTGGCACCA TCCCCCAGGC CAAGCCCACC
CCGGTGTCCC CAGCAACCTC CAGTGCCAGC ACCATGCCTG TAAGAGGGGG CACCCGCCTC
GCCCAGGAAG CTGCTTCTAA ACTGACGAGG GCTCCCGACT CTCCCTCCTC TGTGGGAAGG
CCTAGTTCAG ATCCAGGTCT GTCCCCAACA CAGCCATGCC CAGAGGGGTC TGGTGATTGC
AGAAAGCAGT GTGAGCCCGA CTACTACCTG GACGAGGCCG GCCGCTGCAC GGCCTGCGTG
AGCTGTTCTC GAGATGACCT TGTGGAGAAG ACGCCATGTG CATGGAACTC CTCCCGCACC
TGCGAATGTC GACCTGGCAT GATCTGTGCC ACATCAGCCA CCAACTCCTG TGCCCGCTGT
GTCCCCTACC CAATCTGTGC AGCAGAGACG GTCACCAAGC CCCAGGATAT GGCTGAGAAG
GACACCACCT TTGAGGCGCC ACCCCTGGGG ACCCAGCCGG ACTGCAACCC CACCCCAGAG
AATGGCGAGG CGCCTGCCAG CACCAGCCCC ACTCAGAGCT TGCTGGTGGA CTCCCAGGCC
AGTAAGACGC TGCCCATCCC AACCAGCGCT CCCGTCGCTC TCTCCTCCAC GGGGAAGCCC
GTTCTGGATG CAGGGCCAGT GCTCTTCTGG GTGATCCTGG TGTTGGTTGT GGTGGTCGGC
TCCAGCGCCT TCCTCCTGTG CCACCGGAGG GCCTGCAGGA AGCGAATTCG GCAGAAGCTC
CACCTGTGCT ACCCGGTCCA GACCTCCCAG CCCAAGCTAG AGCTTGTGGA TTCCAGACCC
AGGAGGAGCT CAACGCAGCT GAGGAGTGGT GCGTCGGTGA CAGAACCCGT CGCGGAAGAG
CGAGGGTTAA TGAGCCAGCC ACTGATGGAG ACCTGCCACA GCGTGGGGGC AGCCTACCTG
GAGAGCCTGC CGCTGCAGGA TGCCAGCCCG GCCGGGGGCC CCTCGTCCCC CAGGGACCTT
CCTGAGCCCC GGGTGTCCAC GGAGCACACC AATAACAAGA TTGAGAAAAT CTACATCATG
AAGGCTGACA CCGTGATCGT GGGGACCGTG AAGGCTGAGC TGCCGGAGGG CCGGGGCCTG
GCGGGGCCAG CAGAGCCCGA GTTGGAGGAG GAGCTGGAGG CGGACCATAC CCCCCACTAC
CCCGAGCAGG AGACAGAACC GCCTCTGGGC AGCTGCAGCG ATGTCATGCT CTCAGTGGAA
GAGGAAGGGA AAGAAGACCC CTTGCCCACA GCTGCCTCTG GAAAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001234.3
CDS223..2010
Misc Feature(1)79..81(+)
Misc Feature(2)271..615(+)
Misc Feature(3)304..420(+)
Misc Feature(4)307..417(+)
Misc Feature(5)424..540(+)
Misc Feature(6)424..540(+)
Misc Feature(7)541..672(+)
Misc Feature(8)544..615(+)
Misc Feature(9)739..1140(+)
Misc Feature(10)832..942(+)
Misc Feature(11)835..945(+)
Misc Feature(12)949..1065(+)
Misc Feature(13)949..1065(+)
Misc Feature(14)1066..1197(+)
Misc Feature(15)1069..1140(+)
Misc Feature(16)1360..1443(+)
Misc Feature(17)1576..1578(+)
Exon (1)1..285
Gene:TNFRSF8
Gene Synonym:
Exon (2)286..373
Gene:TNFRSF8
Gene Synonym:
Exon (3)374..490
Gene:TNFRSF8
Gene Synonym:
Exon (4)491..643
Gene:TNFRSF8
Gene Synonym:
Exon (5)644..734
Gene:TNFRSF8
Gene Synonym:
Exon (6)735..898
Gene:TNFRSF8
Gene Synonym:
Exon (7)899..1015
Gene:TNFRSF8
Gene Synonym:
Exon (8)1016..1168
Gene:TNFRSF8
Gene Synonym:
Exon (9)1169..1262
Gene:TNFRSF8
Gene Synonym:
Exon (10)1263..1375
Gene:TNFRSF8
Gene Synonym:
Exon (11)1376..1477
Gene:TNFRSF8
Gene Synonym:
Exon (12)1478..1531
Gene:TNFRSF8
Gene Synonym:
Exon (13)1532..1557
Gene:TNFRSF8
Gene Synonym:
Exon (14)1558..1765
Gene:TNFRSF8
Gene Synonym:
Exon (15)1766..3686
Gene:TNFRSF8
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001243
Organism Homo sapiens (human)
Definition Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001243

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGCGCGTCC TCCTCGCCGC GCTGGGACTG CTGTTCCTGG GGGCGCTACG AGCCTTCCCA 
CAGGATCGAC CCTTCGAGGA CACCTGTCAT GGAAACCCCA GCCACTACTA TGACAAGGCT
GTCAGGAGGT GCTGTTACCG CTGCCCCATG GGGCTGTTCC CGACACAGCA GTGCCCACAG
AGGCCTACTG ACTGCAGGAA GCAGTGTGAG CCTGACTACT ACCTGGATGA GGCCGACCGC
TGTACAGCCT GCGTGACTTG TTCTCGAGAC GACCTCGTGG AGAAGACGCC GTGTGCATGG
AACTCCTCCC GTGTCTGCGA ATGTCGACCC GGCATGTTCT GTTCCACGTC TGCCGTCAAC
TCCTGTGCCC GCTGCTTCTT CCATTCTGTC TGTCCGGCAG GGATGATTGT CAAGTTCCCA
GGCACGGCGC AGAAGAACAC GGTCTGTGAG CCGGCTTCCC CAGGGGTCAG CCCTGCCTGT
GCCAGCCCAG AGAACTGCAA GGAACCCTCC AGTGGCACCA TCCCCCAGGC CAAGCCCACC
CCGGTGTCCC CAGCAACCTC CAGTGCCAGC ACCATGCCTG TAAGAGGGGG CACCCGCCTC
GCCCAGGAAG CTGCTTCTAA ACTGACGAGG GCTCCCGACT CTCCCTCCTC TGTGGGAAGG
CCTAGTTCAG ATCCAGGTCT GTCCCCAACA CAGCCATGCC CAGAGGGGTC TGGTGATTGC
AGAAAGCAGT GTGAGCCCGA CTACTACCTG GACGAGGCCG GCCGCTGCAC GGCCTGCGTG
AGCTGTTCTC GAGATGACCT TGTGGAGAAG ACGCCATGTG CATGGAACTC CTCCCGCACC
TGCGAATGTC GACCTGGCAT GATCTGTGCC ACATCAGCCA CCAACTCCTG TGCCCGCTGT
GTCCCCTACC CAATCTGTGC AGCAGAGACG GTCACCAAGC CCCAGGATAT GGCTGAGAAG
GACACCACCT TTGAGGCGCC ACCCCTGGGG ACCCAGCCGG ACTGCAACCC CACCCCAGAG
AATGGCGAGG CGCCTGCCAG CACCAGCCCC ACTCAGAGCT TGCTGGTGGA CTCCCAGGCC
AGTAAGACGC TGCCCATCCC AACCAGCGCT CCCGTCGCTC TCTCCTCCAC GGGGAAGCCC
GTTCTGGATG CAGGGCCAGT GCTCTTCTGG GTGATCCTGG TGTTGGTTGT GGTGGTCGGC
TCCAGCGCCT TCCTCCTGTG CCACCGGAGG GCCTGCAGGA AGCGAATTCG GCAGAAGCTC
CACCTGTGCT ACCCGGTCCA GACCTCCCAG CCCAAGCTAG AGCTTGTGGA TTCCAGACCC
AGGAGGAGCT CAACGCAGCT GAGGAGTGGT GCGTCGGTGA CAGAACCCGT CGCGGAAGAG
CGAGGGTTAA TGAGCCAGCC ACTGATGGAG ACCTGCCACA GCGTGGGGGC AGCCTACCTG
GAGAGCCTGC CGCTGCAGGA TGCCAGCCCG GCCGGGGGCC CCTCGTCCCC CAGGGACCTT
CCTGAGCCCC GGGTGTCCAC GGAGCACACC AATAACAAGA TTGAGAAAAT CTACATCATG
AAGGCTGACA CCGTGATCGT GGGGACCGTG AAGGCTGAGC TGCCGGAGGG CCGGGGCCTG
GCGGGGCCAG CAGAGCCCGA GTTGGAGGAG GAGCTGGAGG CGGACCATAC CCCCCACTAC
CCCGAGCAGG AGACAGAACC GCCTCTGGGC AGCTGCAGCG ATGTCATGCT CTCAGTGGAA
GAGGAAGGGA AAGAAGACCC CTTGCCCACA GCTGCCTCTG GAAAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Protrusion-guided extracellular vesicles mediate CD30 trans-signalling in the microenvironment of Hodgkin's lymphoma
J. Pathol. 232 (4), 405-414 (2014)
Hansen HP, Engels HM, Dams M, Paes Leme AF, Pauletti BA, Simhadri VL, Durkop H, Reiners KS, Barnert S, Engert A, Schubert R, Quondamatteo F, Hallek M and Pogge von Strandmann E.


book

Loss of Foxp3 is associated with CD30 expression in the anaplastic large cell subtype of adult T-cell leukemia/lymphoma (ATLL) in US/Caribbean patients: potential therapeutic implications for CD30 antibody-mediated therapy
Am. J. Surg. Pathol. 37 (9), 1407-1412 (2013)
Yao J, Gottesman SR, Ayalew G, Braverman AS and Axiotis CA.


book

Differential expression of CD30 on CD3 T lymphocytes in patients with systemic lupus erythematosus
Scand. J. Immunol. 78 (3), 306-312 (2013)
Cabrera CM, Urra JM, Carreno A and Zamorano J.


book

Release of soluble CD30 after allogeneic stimulation is mediated by memory T cells and regulated by IFN-gamma and IL-2
Transplantation 96 (2), 154-161 (2013)
Velasquez SY, Garcia LF, Opelz G, Alvarez CM and Susal C.


book

Soluble CD26 and CD30 levels in patients with common variable immunodeficiency
J Investig Allergol Clin Immunol 23 (2), 120-124 (2013)
Mahmoudi M, Hedayat M, Aghamohammadi A and Rezaei N.


book

Opposite effects of the CD30 ligand are not due to CD30 mutations: results from cDNA cloning and sequence comparison of the CD30 antigen from different sources
Mol. Immunol. 31 (17), 1329-1334 (1994)
Jung W, Krueger S, Renner C, Gause A, Sahin U, Trumper L and Pfreundschuh M.


book

Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3
Oncogene 9 (6), 1567-1574 (1994)
Shiota M, Fujimoto J, Semba T, Satoh H, Yamamoto T and Mori S.


book

Assignment of the human CD30 (Ki-1) gene to 1p36
Genomics 14 (3), 825-826 (1992)
Fonatsch C, Latza U, Durkop H, Rieder H and Stein H.


book

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease
Cell 68 (3), 421-427 (1992)
Durkop H, Latza U, Hummel M, Eitelbach F, Seed B and Stein H.


book

Ki-1 (CD30) antigen is released by Ki-1-positive tumor cells in vitro and in vivo. I. Partial characterization of soluble Ki-1 antigen and detection of the antigen in cell culture supernatants and in serum by an enzyme-linked immunosorbent assay
Eur. J. Immunol. 19 (1), 157-162 (1989)
Josimovic-Alasevic O, Durkop H, Schwarting R, Backe E, Stein H and Diamantstein T.


 
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