Gene Symbol | Washc1 |
Entrez Gene ID | 68767 |
Full Name | WASH complex subunit 1 |
Synonyms | 1110049F14Rik,ORF19,Wash,Wash1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Washc1 cDNA ORF clone
gRNAs
Gene Symbol | Washc1 |
Entrez Gene ID | 68767 |
Full Name | WASH complex subunit 1 |
Synonyms | 1110049F14Rik,ORF19,Wash,Wash1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006524860.2 | XP_006524923.1 | WAS protein family homolog 1 isoform X1 |
XM_030250023.1 | XP_030105883.1 | WASH complex subunit 1 isoform X1 |
XM_030250021.1 | XP_030105881.1 | WASH complex subunit 1 isoform X1 |
XM_030250022.1 | XP_030105882.1 | WASH complex subunit 1 isoform X1 |
XM_030250024.1 | XP_030105884.1 | WASH complex subunit 1 isoform X1 |
NM_001037757.1 | NP_001032846.1 | WASH complex subunit 1 |
XM_006524860.3 | XP_006524923.1 | WAS protein family homolog 1 isoform X1 |
XM_006524859.1 | XP_006524922.1 | WASH complex subunit 1 isoform X2 |
XM_006524860.4 | XP_006524923.1 | WASH complex subunit 1 isoform X2 |
NM_026833.1 | NP_081109.1 | WASH complex subunit 1 |
Canis lupus familiaris (dog) | WASH1 | XP_543873.2 |
LOC706500 | XP_001094494.2 | |
Bos taurus (cattle) | WASH1 | NP_001098876.1 |
Danio rerio (zebrafish) | wash | NP_001103920.1 |
Pan troglodytes (chimpanzee) | WASH1 | XP_001146063.2 |
Mus musculus (house mouse) | Wash | NP_001032846.1 |
Gallus gallus (chicken) | WASH1 | NP_001006245.1 |
Homo sapiens (human) | WASH1 | NP_878908.4 |
Rattus norvegicus (Norway rat) | Wash | NP_001120862.1 |
Drosophila melanogaster (fruit fly) | wash | NP_610739.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010756 | XP_318555.4 |
Xenopus tropicalis (tropical clawed frog) | wash1 | NP_001016854.1 |
WASH maintains NKp46
Xia P, Liu J, Wang S, Ye B, Du Y, Xiong Z, Han ZG, Tong L, Fan Z
Nature communications815685(2017 Jun)
Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.
Tyrrell BJ, Woodham EF, Spence HJ, Strathdee D, Insall RH, Machesky LM
Pigment cell & melanoma research29(5)559-71(2016 Sep)
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A, Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B, Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH, van de Sluis B
Nature communications710961(2016 Mar)
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
Xia P, Wang S, Huang G, Zhu P, Li M, Ye B, Du Y, Fan Z
The Journal of experimental medicine211(10)2119-34(2014 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
WASH is required for the differentiation commitment of hematopoietic stem cells by acting as an upstream regulator to modulate c-Myc transcription.
Title: WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
WASH deficiency impairs the association of RNF2 with AMBRA1 to impede AMBRA1 degradation.
Title: RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy.
WASH complex regulates Arp2/3 complex and is required for cytokinesis and polar body extrusion.
Title: WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes.
WASH can suppress Beclin 1 ubiquitination to inactivate Vps34 activity leading to suppression of autophagy.
Title: WASH inhibits autophagy through suppression of Beclin 1 ubiquitination.
WASH is a newly recognized regulator of T cell receptor, CD28, LFA-1, and GLUT1 endosome-to-membrane recycling.
Title: WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.
The following Washc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Washc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu22213 | |
Clone ID Related Accession (Same CDS sequence) | XM_006524860.2 , NM_001037757.1 , XM_006524860.3 , XM_006524859.1 , XM_006524860.4 , NM_026833.1 | |
Accession Version | NM_001037757.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-16 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY339670.1, AK159820.1 and AC119957.9. On Dec 16, 2005 this sequence version replaced XM_896922.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK154400.1, AK033616.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001032846.1 |
CDS | 93..1520 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22213 | |
Clone ID Related Accession (Same CDS sequence) | XM_006524860.2 , NM_001037757.1 , XM_006524860.3 , XM_006524859.1 , XM_006524860.4 , NM_026833.1 | |
Accession Version | NM_026833.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-16 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY275336.1, AK159820.1 and AC119957.9. On or before Dec 16, 2005 this sequence version replaced XM_128709.6, XM_915458.1. Transcript Variant: This variant (1) and variant 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK171737.1, BC025839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_081109.1 |
CDS | 110..1537 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22213 | |
Clone ID Related Accession (Same CDS sequence) | XM_006524860.2 , NM_001037757.1 , XM_006524860.3 , XM_006524859.1 , XM_006524860.4 , NM_026833.1 | |
Accession Version | XM_006524860.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | WAS protein family homolog 1 isoform X1 | |
Comment |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006524923.1 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22213 | |
Clone ID Related Accession (Same CDS sequence) | XM_006524860.2 , NM_001037757.1 , XM_006524860.3 , XM_006524859.1 , XM_006524860.4 , NM_026833.1 | |
Accession Version | XM_006524860.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | WAS protein family homolog 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006524860.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006524923.1 |
CDS | 145..1572 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22213 | |
Clone ID Related Accession (Same CDS sequence) | XM_006524860.2 , NM_001037757.1 , XM_006524860.3 , XM_006524859.1 , XM_006524860.4 , NM_026833.1 | |
Accession Version | XM_006524859.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006524922.1 |
CDS | 252..1679 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22213 | |
Clone ID Related Accession (Same CDS sequence) | XM_006524860.2 , NM_001037757.1 , XM_006524860.3 , XM_006524859.1 , XM_006524860.4 , NM_026833.1 | |
Accession Version | XM_006524860.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006524860.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006524923.1 |
CDS | 202..1629 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu87259 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250023.1 , XM_030250021.1 , XM_030250022.1 , XM_030250024.1 | |
Accession Version | XM_030250023.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030105883.1 |
CDS | 252..1796 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu87259 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250023.1 , XM_030250021.1 , XM_030250022.1 , XM_030250024.1 | |
Accession Version | XM_030250021.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030105881.1 |
CDS | 127..1671 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu87259 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250023.1 , XM_030250021.1 , XM_030250022.1 , XM_030250024.1 | |
Accession Version | XM_030250022.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030105882.1 |
CDS | 93..1637 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu87259 | |
Clone ID Related Accession (Same CDS sequence) | XM_030250023.1 , XM_030250021.1 , XM_030250022.1 , XM_030250024.1 | |
Accession Version | XM_030250024.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | WASH complex subunit 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030105884.1 |
CDS | 146..1690 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACACCGG TGAAGACCCA GTGCTCCTTG GCGGGCCAGC TTTATGCAGT GCCCCTCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
WASH maintains NKp46 |
Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour. |
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. |
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner. |