| Gene Symbol | TRPC1 |
| Entrez Gene ID | 100009352 |
| Full Name | transient receptor potential cation channel subfamily C member 1 |
| Synonyms | TRPC1A |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
IVD Raw Materials
ORF » Species Summary » Oryctolagus cuniculus » TRPC1 cDNA ORF clone
| Gene Symbol | TRPC1 |
| Entrez Gene ID | 100009352 |
| Full Name | transient receptor potential cation channel subfamily C member 1 |
| Synonyms | TRPC1A |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
| mRNA | Protein | Name |
|---|---|---|
| XM_008266184.2 | XP_008264406.1 | short transient receptor potential channel 1 isoform X2 |
| XM_017346639.1 | XP_017202128.1 | short transient receptor potential channel 1 isoform X3 |
| NM_001082651.1 | NP_001076120.1 | short transient receptor potential channel 1 |
| XM_008266183.2 | XP_008264405.1 | short transient receptor potential channel 1 isoform X1 |
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries.
Greenberg HZE, Carlton-Carew SRE, Khan DM, Zargaran AK, Jahan KS, Vanessa Ho WS, Albert AP
Vascular pharmacology96-9853-62(2017 Sep)
Store depletion induces G?q-mediated PLC?1 activity to stimulate TRPC1 channels in vascular smooth muscle cells.
Shi J, Miralles F, Birnbaumer L, Large WA, Albert AP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology30(2)702-15(2016 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Heteromeric TRPV4-TRPC1 channels mediate CaSR-induced vasorelaxation through NO production but not IKCa channel activation in rabbit mesenteric arteries.
Title: Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries.
a novel activation mechanism for TRPC1 SOCs in VSMCs, in which store depletion induces formation of TRPC1-Galphaq-PLCbeta1 complexes that lead to PKC stimulation and channel gating.
Title: Store depletion induces G?q-mediated PLC?1 activity to stimulate TRPC1 channels in vascular smooth muscle cells.
The following TRPC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRPC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OOb30193 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001082651.1 | |
| Accession Version | NM_001082651.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2280bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-11-09 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | short transient receptor potential channel 1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF170493.1. ##Evidence-Data-START## Transcript exon combination :: AF170493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1876831, SAMEA1876850 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGATGGCGG CCCTGTACCC GAGTACGGAC CTCTCGGGCG CCTCCTCCTC CTCCCTGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001076120.1 |
| CDS | 1..2280 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001082651.1 |
1 | ATGATGGCGG CCCTGTACCC GAGTACGGAC CTCTCGGGCG CCTCCTCCTC CTCCCTGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OOb15231 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008266183.2 | |
| Accession Version | XM_008266183.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2382bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-22 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | short transient receptor potential channel 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013682.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008266183.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGATGGCGG CCCTGTACCC GACTACGGAC CTCTCGGGCG CCTCCTCCTC CTCCCTGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008264405.1 |
| CDS | 481..2862 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008266183.2 |
1 | ATGATGGCGG CCCTGTACCC GACTACGGAC CTCTCGGGCG CCTCCTCCTC CTCCCTGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OOb15232 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008266184.2 | |
| Accession Version | XM_008266184.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-22 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | short transient receptor potential channel 1 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013682.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 23, 2016 this sequence version replaced XM_008266184.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGTTAAAA AGATTTTGGA GGAAAACAGT TCAGGTGACT TGAACATAAA TTGCGTAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008264406.1 |
| CDS | 389..2587 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008266184.2 |
1 | ATGGTTAAAA AGATTTTGGA GGAAAACAGT TCAGGTGACT TGAACATAAA TTGCGTAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OOb36484 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017346639.1 | |
| Accession Version | XM_017346639.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-22 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | short transient receptor potential channel 1 isoform X3 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013682.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAGAAGCT TTTCTTGCTG GCGTGCGACA AGGAAACTCA TGGAACGGAT TCAGAATCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017202128.1 |
| CDS | 121..2106 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017346639.1 |
1 | ATGAGAAGCT TTTCTTGCTG GCGTGCGACA AGGAAACTCA TGGAACGGAT TCAGAATCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries. |
Store depletion induces G?q-mediated PLC?1 activity to stimulate TRPC1 channels in vascular smooth muscle cells. |