Adam6a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adam6a
Entrez Gene ID	192271
Full Name	a disintegrin and metallopeptidase domain 6
Synonyms	TMDCIV
General protein information	Preferred Names a disintegrin and metallopeptidase domain 6 Names a disintegrin and metallopeptidase domain 6 a disintegrin and metalloproteinase domain 6 tMDC IV
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32
Summary	metalloprotease-disintegrin with high similarity to human metargidin; may participate in dual proteolysis and integrin-mediated cell-cell, cell-matrix interaction [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_138906.1	NP_620261.1	a disintegrin and metallopeptidase domain 6A precursor

Pathways from BioSystems

Homologies

	LOC704251	XP_001088316.1
Bos taurus (cattle)	LOC100337054	XP_002683684.2
Rattus norvegicus (Norway rat)	Adam6	NP_620261.1
	LOC701709	XP_001088207.1

Gene Ontology
Bibliography

Related articles in PubMed

Lack of tyrosylprotein sulfotransferase-2 activity results in altered sperm-egg interactions and loss of ADAM3 and ADAM6 in epididymal sperm.
Marcello MR, Jia W, Leary JA, Moore KL, Evans JP
The Journal of biological chemistry286(15)13060-70(2011 Apr)

Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice.
Han C, Choi E, Park I, Lee B, Jin S, Kim DH, Nishimura H, Cho C
Biology of reproduction80(5)1001-8(2009 May)

Chronological gene expression of ADAMs during testicular development: prespermatogonia (gonocytes) express fertilin beta (ADAM2).
Rosselot C, Kierszenbaum AL, Rivkin E, Tres LL
Developmental dynamics : an official publication of the American Association of Anatomists227(3)458-67(2003 Jul)

Rat MDC family of proteins: sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis.
Frayne J, Jury JA, Barker HL, Hall L
Molecular reproduction and development48(2)159-67(1997 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Adam6a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adam6a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42182	NM_138906.1 Latest version!	Rattus norvegicus a disintegrin and metallopeptidase domain 6A (Adam6a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adam6a ( NM_138906.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620261.1 Rattus norvegicus a disintegrin and metallopeptidase domain 6A (Adam6a), mRNA.

Price & Availability↑

CloneID	ORa42182
Clone ID Related Accession (Same CDS sequence)	NM_138906.1
Accession Version	NM_138906.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	a disintegrin and metallopeptidase domain 6A precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y09111.1. ##Evidence-Data-START## Transcript exon combination :: Y09111.1 [ECO:0000332] ##Evidence-Data-END##

ATGTTATCTC TGACCTGGGG TATGAAGCTA GTGGAAAGAT CTGTGGTCCC CAGGGTCCTC 
CTCTTGCTCT TTGCACTCTG GCTGCTCCTC CTGGTTCCAG TCCGGTGTTC TGAAGGCCAC 
CCCACTTGGC GCTACATCTC ATCAGAGGTG GTTATTCCTC GGAAGGAGAT CTACCACAGC 
AAAGGAATTC AAACACAAGG ACGGCTCTCC TATAGCTTGC GTTTTAGGGG CCAGAGACAT 
ATCATCCACC TGCGAAGAAA GACACTAATT TGGCCCAGAC ACTTGTTGCT GACAACTCAG 
GATGACCAAG GAGCCTTACA GATGGATTAC CCTTTTTTCC CTGTAGATTG TTACTATTTT 
GGCTACCTAG AGGGAATCCC TCAATCCATG GTCACTGTGA ATACTTGCTA TGGAGGCCTG 
GAAGGGATCA TGATGTTGGA TGACCTTGCC TATGAAATCA AACCCCTCAA CGATTCACAG 
GGGTTTGAAC ACATTGTTTC TCAGATAGTA TCAGAGCCTG ATGTAACAGG GCCTACAAAT 
ACATGGAAAC GCTTGAACCT TAATACAGGT CCTCCCTTAT CCAGGACAGA GTATGCCAAT 
GGAACTCCCA GAATGTCTAG TAAGAACTAC GCTTCACATC CAGCTGCTAT AAAAGGCCAA 
TTCCAAGCAA CTAATTCTAT ATATAAGGAA AGCAACAATA TTGATACTGC GGCCAGGTAT 
TTGTTTGAGC TCCTTAGTAT AACGGACAGC TTTCTGATCA CTATTCATAT GCGGTACTAT 
GCTATTCTCT TAACTGTGTT TACCGAGAGC GATCCATTTG CACTAGAGTA TACGGTACCA 
GGGGGCTCTA TTTATAACTA TTATGTGTCT AACTTTTTTA ATCGGTTGAG GCCTGATGCA 
TCAACCGTAC TTAATAAAGA TGGGCCCTCG GATAACGACT TTCATCCAGT TGAACAGAGT 
TTATGTACTC CCGCAGGCCT GACGATTGTT GGTCAACACA GACGAAGTTT TCTAGCTCTA 
TCTGTTATGA TCACCAATCG TATTGCGATG TCTTTAGGTA TAAAAGCTGA TGATGAGACT 
TACTGCATCT GCCACAGAAG GACCACTTGC ATTATGTACA AAAACCCTGA AATAACAGAT 
GCTTTCAGCA ATTGCTCCCT TGTGCAGATA AACCAGATAC TGAATACCCC TGGTACAATG 
TCATGCCTTT TCTATGACCA CCATGTTTAT CATAATATAA CAAAAACCTA CAGGTTTTGT 
GGAAACTTCA AGATAGATAT CGGTGAGCAG TGTGACTGTG GCTCACATAA GGCATGTTAC 
GCAGATCCCT GCTGCGGAAG TAATTGCAAG TTAACTGCTG GTAGCATTTG TGATAAAGAA 
TTATGCTGTG CAAACTGCAC CTACAGTCCT TCTGGGACAC TCTGCAGACC GATCCAGAAC 
ATATGTGATC TTCCAGAATA CTGTAGTGGG AATAATATCT TTTGCCCTGC AGACACTTAT 
CTGCAAGATG GGACGCCATG CTCAGAAGAG GGGTACTGCT ATAAAGGCAA CTGCACAGAT 
CGCAGTGTGC AGTGCAAGGA AATCTTTGGT ATGAATGCTA AGGGTGCTAA TATCAAGTGC 
TATGACATCA ACAAACAACG GTTTCGATTT GGGCACTGCA CTAGAGCACA AGAGAGCCTC 
ATGTTTAATG CTTGCTCTGA TCATGATAAA CTGTGTGGAA GGCTGCAGTG TACCAACGTC 
ACCAATCTTC CATTCCTGCA GGAACATGTT TCATTCCATC AATCGGTTAT CTCTGGGTTT 
ACCTGCTTTG GGCTTGATGA ACATCGTGGG ACAGAAACAA CGGATGCTGG GCTGGTGAAA 
CATGGTACCC CTTGCTCCCA AACTAACTTC TGCGATCGAG GAGCTTGCAA TGGAAGTTTA 
TCTCGGTTGG ATTATGACTG CACCCCAGAA AAATGCAATT TTAGAGGAGT GTGTAATAAT 
CATCGGCATT GCCATTGTCA TTTAGGTTGG AAACCTCCTC TGTGCAGAGA GGAGGGGCCT 
AGCGGGAGCA CGGACAGTGG GTCCCCTCCG AAGGAAAGGC GCACAATAAA ACAGAGCAGA 
GAACCACTGT TATATTTAAG AATGCTCTTT GGTCGTCTTT ATTTATTCAT TGTCTCGCTG 
CTCTTTGGAG TGGCCACTCG CGCAGGAGTT ATTAAGGTCT TTAAGTTTGA AGACTTGCAA 
GCTGCTCTGC GGGCTGCACA AGCCAAGGCG ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620261.1
CDS	39..2294
Translation	MLSLTWGMKLVERSVVPRVLLLLFALWLLLLVPVRCSEGHPTWRYISSEVVIPRKEIYHSKGIQTQGRLSYSLRFRGQRHIIHLRRKTLIWPRHLLLTTQDDQGALQMDYPFFPVDCYYFGYLEGIPQSMVTVNTCYGGLEGIMMLDDLAYEIKPLNDSQGFEHIVSQIVSEPDVTGPTNTWKRLNLNTGPPLSRTEYANGTPRMSSKNYASHPAAIKGQFQATNSIYKESNNIDTAARYLFELLSITDSFLITIHMRYYAILLTVFTESDPFALEYTVPGGSIYNYYVSNFFNRLRPDASTVLNKDGPSDNDFHPVEQSLCTPAGLTIVGQHRRSFLALSVMITNRIAMSLGIKADDETYCICHRRTTCIMYKNPEITDAFSNCSLVQINQILNTPGTMSCLFYDHHVYHNITKTYRFCGNFKIDIGEQCDCGSHKACYADPCCGSNCKLTAGSICDKELCCANCTYSPSGTLCRPIQNICDLPEYCSGNNIFCPADTYLQDGTPCSEEGYCYKGNCTDRSVQCKEIFGMNAKGANIKCYDINKQRFRFGHCTRAQESLMFNACSDHDKLCGRLQCTNVTNLPFLQEHVSFHQSVISGFTCFGLDEHRGTETTDAGLVKHGTPCSQTNFCDRGACNGSLSRLDYDCTPEKCNFRGVCNNHRHCHCHLGWKPPLCREEGPSGSTDSGSPPKERRTIKQSREPLLYLRMLFGRLYLFIVSLLFGVATRAGVIKVFKFEDLQAALRAAQAKAT

Target ORF information:

RefSeq Version	NM_138906.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus a disintegrin and metallopeptidase domain 6A (Adam6a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138906.1

ORF Insert Sequence:

ATGTTATCTC TGACCTGGGG TATGAAGCTA GTGGAAAGAT CTGTGGTCCC CAGGGTCCTC 
CTCTTGCTCT TTGCACTCTG GCTGCTCCTC CTGGTTCCAG TCCGGTGTTC TGAAGGCCAC 
CCCACTTGGC GCTACATCTC ATCAGAGGTG GTTATTCCTC GGAAGGAGAT CTACCACAGC 
AAAGGAATTC AAACACAAGG ACGGCTCTCC TATAGCTTGC GTTTTAGGGG CCAGAGACAT 
ATCATCCACC TGCGAAGAAA GACACTAATT TGGCCCAGAC ACTTGTTGCT GACAACTCAG 
GATGACCAAG GAGCCTTACA GATGGATTAC CCTTTTTTCC CTGTAGATTG TTACTATTTT 
GGCTACCTAG AGGGAATCCC TCAATCCATG GTCACTGTGA ATACTTGCTA TGGAGGCCTG 
GAAGGGATCA TGATGTTGGA TGACCTTGCC TATGAAATCA AACCCCTCAA CGATTCACAG 
GGGTTTGAAC ACATTGTTTC TCAGATAGTA TCAGAGCCTG ATGTAACAGG GCCTACAAAT 
ACATGGAAAC GCTTGAACCT TAATACAGGT CCTCCCTTAT CCAGGACAGA GTATGCCAAT 
GGAACTCCCA GAATGTCTAG TAAGAACTAC GCTTCACATC CAGCTGCTAT AAAAGGCCAA 
TTCCAAGCAA CTAATTCTAT ATATAAGGAA AGCAACAATA TTGATACTGC GGCCAGGTAT 
TTGTTTGAGC TCCTTAGTAT AACGGACAGC TTTCTGATCA CTATTCATAT GCGGTACTAT 
GCTATTCTCT TAACTGTGTT TACCGAGAGC GATCCATTTG CACTAGAGTA TACGGTACCA 
GGGGGCTCTA TTTATAACTA TTATGTGTCT AACTTTTTTA ATCGGTTGAG GCCTGATGCA 
TCAACCGTAC TTAATAAAGA TGGGCCCTCG GATAACGACT TTCATCCAGT TGAACAGAGT 
TTATGTACTC CCGCAGGCCT GACGATTGTT GGTCAACACA GACGAAGTTT TCTAGCTCTA 
TCTGTTATGA TCACCAATCG TATTGCGATG TCTTTAGGTA TAAAAGCTGA TGATGAGACT 
TACTGCATCT GCCACAGAAG GACCACTTGC ATTATGTACA AAAACCCTGA AATAACAGAT 
GCTTTCAGCA ATTGCTCCCT TGTGCAGATA AACCAGATAC TGAATACCCC TGGTACAATG 
TCATGCCTTT TCTATGACCA CCATGTTTAT CATAATATAA CAAAAACCTA CAGGTTTTGT 
GGAAACTTCA AGATAGATAT CGGTGAGCAG TGTGACTGTG GCTCACATAA GGCATGTTAC 
GCAGATCCCT GCTGCGGAAG TAATTGCAAG TTAACTGCTG GTAGCATTTG TGATAAAGAA 
TTATGCTGTG CAAACTGCAC CTACAGTCCT TCTGGGACAC TCTGCAGACC GATCCAGAAC 
ATATGTGATC TTCCAGAATA CTGTAGTGGG AATAATATCT TTTGCCCTGC AGACACTTAT 
CTGCAAGATG GGACGCCATG CTCAGAAGAG GGGTACTGCT ATAAAGGCAA CTGCACAGAT 
CGCAGTGTGC AGTGCAAGGA AATCTTTGGT ATGAATGCTA AGGGTGCTAA TATCAAGTGC 
TATGACATCA ACAAACAACG GTTTCGATTT GGGCACTGCA CTAGAGCACA AGAGAGCCTC 
ATGTTTAATG CTTGCTCTGA TCATGATAAA CTGTGTGGAA GGCTGCAGTG TACCAACGTC 
ACCAATCTTC CATTCCTGCA GGAACATGTT TCATTCCATC AATCGGTTAT CTCTGGGTTT 
ACCTGCTTTG GGCTTGATGA ACATCGTGGG ACAGAAACAA CGGATGCTGG GCTGGTGAAA 
CATGGTACCC CTTGCTCCCA AACTAACTTC TGCGATCGAG GAGCTTGCAA TGGAAGTTTA 
TCTCGGTTGG ATTATGACTG CACCCCAGAA AAATGCAATT TTAGAGGAGT GTGTAATAAT 
CATCGGCATT GCCATTGTCA TTTAGGTTGG AAACCTCCTC TGTGCAGAGA GGAGGGGCCT 
AGCGGGAGCA CGGACAGTGG GTCCCCTCCG AAGGAAAGGC GCACAATAAA ACAGAGCAGA 
GAACCACTGT TATATTTAAG AATGCTCTTT GGTCGTCTTT ATTTATTCAT TGTCTCGCTG 
CTCTTTGGAG TGGCCACTCG CGCAGGAGTT ATTAAGGTCT TTAAGTTTGA AGACTTGCAA 
GCTGCTCTGC GGGCTGCACA AGCCAAGGCG ACTTAA