Nectin3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Nectin3
Entrez Gene ID	288124
Full Name	nectin cell adhesion molecule 3
Synonyms	Pvrl3
General protein information	Preferred Names nectin cell adhesion molecule 3 Names nectin-3 poliovirus receptor-related 3 poliovirus receptor-related protein 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q21

mRNA and Protein(s)

mRNA Protein Name

XM_006248338.3 XP_006248400.1 nectin-3 isoform X2

XM_006248335.2 XP_006248397.1 nectin-3 isoform X1

NM_001105883.1 NP_001099353.1 nectin-3
Pathways from BioSystems

mRNA	Protein	Name
XM_006248338.3	XP_006248400.1	nectin-3 isoform X2
XM_006248335.2	XP_006248397.1	nectin-3 isoform X1
NM_001105883.1	NP_001099353.1	nectin-3

Homologies

Bos taurus (cattle)	PVRL3	XP_002684791.3
Gallus gallus (chicken)	PVRL3	XP_416630.3
Homo sapiens (human)	PVRL3	NP_001230217.1
Canis lupus familiaris (dog)	PVRL3	XP_005639698.1
	PVRL3	XP_001102320.1
Mus musculus (house mouse)	Pvrl3	NP_067471.1
Rattus norvegicus (Norway rat)	Pvrl3	NP_001099353.1

Gene Ontology
Bibliography

Related articles in PubMed

High Resolution Localization of Rab5, EEA1, and Nectin-3 to Tubulobulbar Complexes in the Rat Testis.
Adams A, Wayne Vogl A
Anatomical record (Hoboken, N.J. : 2007)300(6)1160-1170(2017 Jun)

Nectin-3 Is Increased in the Cell Junctions of the Uterine Epithelium at Implantation.
Poon CE, Madawala RJ, Dowland SN, Murphy CR
Reproductive sciences (Thousand Oaks, Calif.)23(11)1580-1592(2016 11)

PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.
Guerrera D, Shah J, Vasileva E, Sluysmans S, M?an I, Jond L, Poser I, Mann M, Hyman AA, Citi S
The Journal of biological chemistry291(21)11016-29(2016 May)

Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations.
van der Kooij MA, Fantin M, Rejmak E, Grosse J, Zanoletti O, Fournier C, Ganguly K, Kalita K, Kaczmarek L, Sandi C
Nature communications54995(2014 Sep)

Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.
Kurita S, Yamada T, Rikitsu E, Ikeda W, Takai Y
The Journal of biological chemistry288(41)29356-68(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Nectin-3 is increased in the cell junctions of the uterine epithelium at implantation. Results suggest that at the time of implantation, nectin-3 may contribute to the formation of the tight junction in a protein complex independent from occludin and l-afadin.
Title: Nectin-3 Is Increased in the Cell Junctions of the Uterine Epithelium at Implantation.

PDZD11 forms a complex with nectin-1 and nectin-3, and its PDZ domain interacts directly with the PDZ-binding motif of nectin-1.
Title: PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.

MMP-9 has a role in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioral alterations
Title: Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations.

critical role of sFRP1 in regulating spermiation via its effects on the FAK signaling and retention of nectin-3 adhesion complex at the apical ectoplasmic specialization
Title: Secreted Frizzled-related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin-3 adhesion protein complex.

The following Nectin3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nectin3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11607	NM_001105883.1 Latest version!	Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa34271	XM_006248335.2 Latest version!	Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
ORa34274	XM_006248338.3 Latest version!	Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nectin3 ( NM_001105883.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099353.1 Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), mRNA.

Price & Availability↑

CloneID	ORa11607
Clone ID Related Accession (Same CDS sequence)	NM_001105883.1
Accession Version	NM_001105883.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	nectin-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473967.1. On or before Oct 3, 2007 this sequence version replaced XM_001059227.1, XM_213626.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCGGA CCCCGGGCCC GGCCCTGTTG TGTCCTGGAG GCGGCAAAGC ACAACTTTCC 
TCGGCGTCTC CTCCCGCGGC CGGACTCCTG CTGCCGGCCC CGACGCCGCC GCCGCTGCTG 
CTGCTGCTCA TTCCCCTGCT TCTCTTCTCC CGGCTCTGTG GTGCCTTAGC TGGATCAATT 
ATTGTGGAGC CGCATGTCAC AGCAGTGTGG GGAAAGAATG TGTCCTTGAA GTGTTTAATT 
GAAGTGAATG AGACTATCAC ACAGATCTCA TGGGAGAAGA TACACGGCAA GAGCACACAG 
ACCGTTGCGG TGCATCATCC TCAGTATGGA TTCTCTGTTC AGGGAGAGTA TCAGGGAAGA 
ATCTTGTTTA AAAACTATTC ACTTAATGAT GCAACAATTA CTCTGCATAA CATAGGCTTC 
TCAGATTCTG GAAAATACAT ATGCAAAGCT GTCACATTCC CACTTGGAAA TGCCCAGTCC 
TCTACAACTG TGACTGTGCT AGTTGAACCC ACCGTGAGCC TGATGAAAGG GCCAGACTCT 
TTAATTGATG GAGGAAATGA GACCGTAGCA GCCGTTTGTA TAGCGGCCAC TGGAAAACCA 
GTTGCACGTA TTGACTGGGA AGGGGATCTC GGCGAAATGG AATCTACTAT AACTTCTTTT 
CCCAATGAAA CAGCAACGAT TATCAGCCAA TACAAGCTGT TTCCCACAAG ATTTGCTAGA 
GGAAGGCGAA TTACTTGTGT TGTAAAACAT CCAGCCTTAG AAAAGGACAT TCGATACTCT 
TTCATACTCG ACATCCAGTA TGCTCCTGAA GTCTCAGTGA CAGGATATGA TGGAAATTGG 
TTTGTGGGAA GAAAAGGTGT TAACCTCAAG TGTAATGCTG ACGCAAATCC TCCACCCTTC 
AAGTCTGTGT GGAGCAGGTT GGATGGAGAA TGGCCTGATG GTTTATTGGC GTCAGACAAT 
ACTCTTCATT TTGTTCATCC ACTGACTTTC AATTATTCTG GTGTTTATGT CTGTAAAGTG 
ACAAATTCCC TTGGTCAAAG AAGTGATCAA AAGGTCATCT ACATTTCAGA CATCCCGCTT 
AAGCAGACCT CATCCATAGC AGTGGCTGGA GCTGTGATTG GAGCTGTCCT GGCCCTCTTC 
ATCATCGCTG TCTTTGTGAC TGTGTTGCTG ACACCTCGGA AAAAGAGACC ATCCTATCTT 
GACAAAGTAA TCGACCTTCC ACCTACACAT AAGCCACCCC CTGTATATGA AGAACGAATT 
CCTTCTCTCC CTCAGAAAAA CCGTCTGTTC CAGACTGAAC GCTTGCCTTT GCAGACTCAG 
TTCAAAGAGA AAGGAGCTGG TGGTCTTCAG CCCCCTAATG GACCAATTAG GAGACTTGAC 
TATGAGGATG AGAACACAGT GCAAGAAGAT GGGACTCAGC AGATGTGCCC CCTTTATAAC 
CAGATGTGCC ACCAAGACCG AAGCCCTCAC CAACATCGCC CACGCAACCC CGAGAGACTC 
TACATCAACC CAAGAGAACA TTATGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099353.1
CDS	12..1541
Translation	MARTPGPALLCPGGGKAQLSSASPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCGALAGSIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGEYQGRILFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLMKGPDSLIDGGNETVAAVCIAATGKPVARIDWEGDLGEMESTITSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGEWPDGLLASDNTLHFVHPLTFNYSGVYVCKVTNSLGQRSDQKVIYISDIPLKQTSSIAVAGAVIGAVLALFIIAVFVTVLLTPRKKRPSYLDKVIDLPPTHKPPPVYEERIPSLPQKNRLFQTERLPLQTQFKEKGAGGLQPPNGPIRRLDYEDENTVQEDGTQQMCPLYNQMCHQDRSPHQHRPRNPERLYINPREHYV

Target ORF information:

RefSeq Version	NM_001105883.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105883.1

ORF Insert Sequence:

ATGGCGCGGA CCCCGGGCCC GGCCCTGTTG TGTCCTGGAG GCGGCAAAGC ACAACTTTCC 
TCGGCGTCTC CTCCCGCGGC CGGACTCCTG CTGCCGGCCC CGACGCCGCC GCCGCTGCTG 
CTGCTGCTCA TTCCCCTGCT TCTCTTCTCC CGGCTCTGTG GTGCCTTAGC TGGATCAATT 
ATTGTGGAGC CGCATGTCAC AGCAGTGTGG GGAAAGAATG TGTCCTTGAA GTGTTTAATT 
GAAGTGAATG AGACTATCAC ACAGATCTCA TGGGAGAAGA TACACGGCAA GAGCACACAG 
ACCGTTGCGG TGCATCATCC TCAGTATGGA TTCTCTGTTC AGGGAGAGTA TCAGGGAAGA 
ATCTTGTTTA AAAACTATTC ACTTAATGAT GCAACAATTA CTCTGCATAA CATAGGCTTC 
TCAGATTCTG GAAAATACAT ATGCAAAGCT GTCACATTCC CACTTGGAAA TGCCCAGTCC 
TCTACAACTG TGACTGTGCT AGTTGAACCC ACCGTGAGCC TGATGAAAGG GCCAGACTCT 
TTAATTGATG GAGGAAATGA GACCGTAGCA GCCGTTTGTA TAGCGGCCAC TGGAAAACCA 
GTTGCACGTA TTGACTGGGA AGGGGATCTC GGCGAAATGG AATCTACTAT AACTTCTTTT 
CCCAATGAAA CAGCAACGAT TATCAGCCAA TACAAGCTGT TTCCCACAAG ATTTGCTAGA 
GGAAGGCGAA TTACTTGTGT TGTAAAACAT CCAGCCTTAG AAAAGGACAT TCGATACTCT 
TTCATACTCG ACATCCAGTA TGCTCCTGAA GTCTCAGTGA CAGGATATGA TGGAAATTGG 
TTTGTGGGAA GAAAAGGTGT TAACCTCAAG TGTAATGCTG ACGCAAATCC TCCACCCTTC 
AAGTCTGTGT GGAGCAGGTT GGATGGAGAA TGGCCTGATG GTTTATTGGC GTCAGACAAT 
ACTCTTCATT TTGTTCATCC ACTGACTTTC AATTATTCTG GTGTTTATGT CTGTAAAGTG 
ACAAATTCCC TTGGTCAAAG AAGTGATCAA AAGGTCATCT ACATTTCAGA CATCCCGCTT 
AAGCAGACCT CATCCATAGC AGTGGCTGGA GCTGTGATTG GAGCTGTCCT GGCCCTCTTC 
ATCATCGCTG TCTTTGTGAC TGTGTTGCTG ACACCTCGGA AAAAGAGACC ATCCTATCTT 
GACAAAGTAA TCGACCTTCC ACCTACACAT AAGCCACCCC CTGTATATGA AGAACGAATT 
CCTTCTCTCC CTCAGAAAAA CCGTCTGTTC CAGACTGAAC GCTTGCCTTT GCAGACTCAG 
TTCAAAGAGA AAGGAGCTGG TGGTCTTCAG CCCCCTAATG GACCAATTAG GAGACTTGAC 
TATGAGGATG AGAACACAGT GCAAGAAGAT GGGACTCAGC AGATGTGCCC CCTTTATAAC 
CAGATGTGCC ACCAAGACCG AAGCCCTCAC CAACATCGCC CACGCAACCC CGAGAGACTC 
TACATCAACC CAAGAGAACA TTATGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nectin3 ( XM_006248335.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248397.1 Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa34271
Clone ID Related Accession (Same CDS sequence)	XM_006248335.2
Accession Version	XM_006248335.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	nectin-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006248335.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTCCT GGGGCGCGGG CGAGCGGATG GACCGGGGCA AGGCGGGCAT GGCGCGGACC 
CCGGGCCCGG CCCTGTTGTG TCCTGGAGGC GGCAAAGCAC AACTTTCCTC GGCGTCTCCT 
CCCGCGGCCG GACTCCTGCT GCCGGCCCCG ACGCCGCCGC CGCTGCTGCT GCTGCTCATT 
CCCCTGCTTC TCTTCTCCCG GCTCTGTGGT GCCTTAGCTG GATCAATTAT TGTGGAGCCG 
CATGTCACAG CAGTGTGGGG AAAGAATGTG TCCTTGAAGT GTTTAATTGA AGTGAATGAG 
ACTATCACAC AGATCTCATG GGAGAAGATA CACGGCAAGA GCACACAGAC CGTTGCGGTG 
CATCATCCTC AGTATGGATT CTCTGTTCAG GGAGAGTATC AGGGAAGAAT CTTGTTTAAA 
AACTATTCAC TTAATGATGC AACAATTACT CTGCATAACA TAGGCTTCTC AGATTCTGGA 
AAATACATAT GCAAAGCTGT CACATTCCCA CTTGGAAATG CCCAGTCCTC TACAACTGTG 
ACTGTGCTAG TTGAACCCAC CGTGAGCCTG ATGAAAGGGC CAGACTCTTT AATTGATGGA 
GGAAATGAGA CCGTAGCAGC CGTTTGTATA GCGGCCACTG GAAAACCAGT TGCACGTATT 
GACTGGGAAG GGGATCTCGG CGAAATGGAA TCTACTATAA CTTCTTTTCC CAATGAAACA 
GCAACGATTA TCAGCCAATA CAAGCTGTTT CCCACAAGAT TTGCTAGAGG AAGGCGAATT 
ACTTGTGTTG TAAAACATCC AGCCTTAGAA AAGGACATTC GATACTCTTT CATACTCGAC 
ATCCAGTATG CTCCTGAAGT CTCAGTGACA GGATATGATG GAAATTGGTT TGTGGGAAGA 
AAAGGTGTTA ACCTCAAGTG TAATGCTGAC GCAAATCCTC CACCCTTCAA GTCTGTGTGG 
AGCAGGTTGG ATGGAGAATG GCCTGATGGT TTATTGGCGT CAGACAATAC TCTTCATTTT 
GTTCATCCAC TGACTTTCAA TTATTCTGGT GTTTATGTCT GTAAAGTGAC AAATTCCCTT 
GGTCAAAGAA GTGATCAAAA GGTCATCTAC ATTTCAGATC CTCCCACTAC CACCACCCTT 
CAGCCTACAG TTCAGTGGCG TTCCTCAACT GCTGACGTCC AGGATCTAGC AACAGAACAT 
AAAAAGTTGC CCTTCCCATT GTCAACTTTG GCAACACTTA AGGATGACAC AATTGGCACC 
ATCATTGCTA GCGTAGTGGG TGGGGCTCTC TTCGTAGTGC TTGTGAGCAT TTTGGCTGGA 
GTATTCTGCT ATAGGAGACG ACGGACGTTT CGTGGAGACT ACTTTGCCAA AAACTACATT 
CCACCATCAG ACATGCAAAA AGAGTCGCAG ATCGATGTTC TTCAACACGA TGAGCATGAT 
TCTTACCCAG ACAGTGTGAA AAAGGAAAAC AAAGCCCCAG TGAACAACCT AATACGTAAA 
GACTACTTAG AAGAGCCCGA GAAAACTCAG TGGAATAATG TAGAGAATCT CACTAGGTTT 
GAAAGACCGA TGGATTATTA CGAAGATCTA AAAATGGGAA TGAAGTTCGT CAGTGATGAA 
CGGTATAATG AAAATGAAGA TGATTTAGTT TCCCATGTAG ATGGTTCCGT AATTTCCAGG 
AGGGAGTGGT ATGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248397.1
CDS	2..1699
Translation	MMSWGAGERMDRGKAGMARTPGPALLCPGGGKAQLSSASPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCGALAGSIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGEYQGRILFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLMKGPDSLIDGGNETVAAVCIAATGKPVARIDWEGDLGEMESTITSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGEWPDGLLASDNTLHFVHPLTFNYSGVYVCKVTNSLGQRSDQKVIYISDPPTTTTLQPTVQWRSSTADVQDLATEHKKLPFPLSTLATLKDDTIGTIIASVVGGALFVVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQHDEHDSYPDSVKKENKAPVNNLIRKDYLEEPEKTQWNNVENLTRFERPMDYYEDLKMGMKFVSDERYNENEDDLVSHVDGSVISRREWYV

Target ORF information:

RefSeq Version	XM_006248335.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248335.2

ORF Insert Sequence:

ATGATGTCCT GGGGCGCGGG CGAGCGGATG GACCGGGGCA AGGCGGGCAT GGCGCGGACC 
CCGGGCCCGG CCCTGTTGTG TCCTGGAGGC GGCAAAGCAC AACTTTCCTC GGCGTCTCCT 
CCCGCGGCCG GACTCCTGCT GCCGGCCCCG ACGCCGCCGC CGCTGCTGCT GCTGCTCATT 
CCCCTGCTTC TCTTCTCCCG GCTCTGTGGT GCCTTAGCTG GATCAATTAT TGTGGAGCCG 
CATGTCACAG CAGTGTGGGG AAAGAATGTG TCCTTGAAGT GTTTAATTGA AGTGAATGAG 
ACTATCACAC AGATCTCATG GGAGAAGATA CACGGCAAGA GCACACAGAC CGTTGCGGTG 
CATCATCCTC AGTATGGATT CTCTGTTCAG GGAGAGTATC AGGGAAGAAT CTTGTTTAAA 
AACTATTCAC TTAATGATGC AACAATTACT CTGCATAACA TAGGCTTCTC AGATTCTGGA 
AAATACATAT GCAAAGCTGT CACATTCCCA CTTGGAAATG CCCAGTCCTC TACAACTGTG 
ACTGTGCTAG TTGAACCCAC CGTGAGCCTG ATGAAAGGGC CAGACTCTTT AATTGATGGA 
GGAAATGAGA CCGTAGCAGC CGTTTGTATA GCGGCCACTG GAAAACCAGT TGCACGTATT 
GACTGGGAAG GGGATCTCGG CGAAATGGAA TCTACTATAA CTTCTTTTCC CAATGAAACA 
GCAACGATTA TCAGCCAATA CAAGCTGTTT CCCACAAGAT TTGCTAGAGG AAGGCGAATT 
ACTTGTGTTG TAAAACATCC AGCCTTAGAA AAGGACATTC GATACTCTTT CATACTCGAC 
ATCCAGTATG CTCCTGAAGT CTCAGTGACA GGATATGATG GAAATTGGTT TGTGGGAAGA 
AAAGGTGTTA ACCTCAAGTG TAATGCTGAC GCAAATCCTC CACCCTTCAA GTCTGTGTGG 
AGCAGGTTGG ATGGAGAATG GCCTGATGGT TTATTGGCGT CAGACAATAC TCTTCATTTT 
GTTCATCCAC TGACTTTCAA TTATTCTGGT GTTTATGTCT GTAAAGTGAC AAATTCCCTT 
GGTCAAAGAA GTGATCAAAA GGTCATCTAC ATTTCAGATC CTCCCACTAC CACCACCCTT 
CAGCCTACAG TTCAGTGGCG TTCCTCAACT GCTGACGTCC AGGATCTAGC AACAGAACAT 
AAAAAGTTGC CCTTCCCATT GTCAACTTTG GCAACACTTA AGGATGACAC AATTGGCACC 
ATCATTGCTA GCGTAGTGGG TGGGGCTCTC TTCGTAGTGC TTGTGAGCAT TTTGGCTGGA 
GTATTCTGCT ATAGGAGACG ACGGACGTTT CGTGGAGACT ACTTTGCCAA AAACTACATT 
CCACCATCAG ACATGCAAAA AGAGTCGCAG ATCGATGTTC TTCAACACGA TGAGCATGAT 
TCTTACCCAG ACAGTGTGAA AAAGGAAAAC AAAGCCCCAG TGAACAACCT AATACGTAAA 
GACTACTTAG AAGAGCCCGA GAAAACTCAG TGGAATAATG TAGAGAATCT CACTAGGTTT 
GAAAGACCGA TGGATTATTA CGAAGATCTA AAAATGGGAA TGAAGTTCGT CAGTGATGAA 
CGGTATAATG AAAATGAAGA TGATTTAGTT TCCCATGTAG ATGGTTCCGT AATTTCCAGG 
AGGGAGTGGT ATGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nectin3 ( XM_006248338.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248400.1 Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa34274
Clone ID Related Accession (Same CDS sequence)	XM_006248338.3
Accession Version	XM_006248338.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	nectin-3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248338.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTCCT GGGGCGCGGG CGAGCGGATG GACCGGGGCA AGGCGGGCAT GGCGCGGACC 
CCGGGCCCGG CCCTGTTGTG TCCTGGAGGC GGCAAAGCAC AACTTTCCTC GGCGTCTCCT 
CCCGCGGCCG GACTCCTGCT GCCGGCCCCG ACGCCGCCGC CGCTGCTGCT GCTGCTCATT 
CCCCTGCTTC TCTTCTCCCG GCTCTGTGGT GCCTTAGCTG GATCAATTAT TGTGGAGCCG 
CATGTCACAG CAGTGTGGGG AAAGAATGTG TCCTTGAAGT GTTTAATTGA AGTGAATGAG 
ACTATCACAC AGATCTCATG GGAGAAGATA CACGGCAAGA GCACACAGAC CGTTGCGGTG 
CATCATCCTC AGTATGGATT CTCTGTTCAG GGAGAGTATC AGGGAAGAAT CTTGTTTAAA 
AACTATTCAC TTAATGATGC AACAATTACT CTGCATAACA TAGGCTTCTC AGATTCTGGA 
AAATACATAT GCAAAGCTGT CACATTCCCA CTTGGAAATG CCCAGTCCTC TACAACTGTG 
ACTGTGCTAG TTGAACCCAC CGTGAGCCTG ATGAAAGGGC CAGACTCTTT AATTGATGGA 
GGAAATGAGA CCGTAGCAGC CGTTTGTATA GCGGCCACTG GAAAACCAGT TGCACGTATT 
GACTGGGAAG GGGATCTCGG CGAAATGGAA TCTACTATAA CTTCTTTTCC CAATGAAACA 
GCAACGATTA TCAGCCAATA CAAGCTGTTT CCCACAAGAT TTGCTAGAGG AAGGCGAATT 
ACTTGTGTTG TAAAACATCC AGCCTTAGAA AAGGACATTC GATACTCTTT CATACTCGAC 
ATCCAGTATG CTCCTGAAGT CTCAGTGACA GGATATGATG GAAATTGGTT TGTGGGAAGA 
AAAGGTGTTA ACCTCAAGTG TAATGCTGAC GCAAATCCTC CACCCTTCAA GTCTGTGTGG 
AGCAGGTTGG ATGGAGAATG GCCTGATGGT TTATTGGCGT CAGACAATAC TCTTCATTTT 
GTTCATCCAC TGACTTTCAA TTATTCTGGT GTTTATGTCT GTAAAGTGAC AAATTCCCTT 
GGTCAAAGAA GTGATCAAAA GGTCATCTAC ATTTCAGACA TCCCGCTTAA GCAGACCTCA 
TCCATAGCAG TGGCTGGAGC TGTGATTGGA GCTGTCCTGG CCCTCTTCAT CATCGCTGTC 
TTTGTGACTG TGTTGCTGAC ACCTCGGAAA AAGAGACCAT CCTATCTTGA CAAAGTGTAT 
GTGTTCCTGA AGACACTTAA ATCACCTGAA CTAGCTTCTA AACGTCTGCC CAGCTGTGGC 
GGCGCACATC TACCTGAGAG GCTGGAGCAG GACCAGAAGC TTAAAGTCGG CCTTGGCTAC 
ACAGTGAGTT CGAGGCCTGC CTGGGCTACT GGAAACCCCA CTGCAAAATT TGAAGTGAAT 
AAATTTTTTA AAAATCCTAT GCCATTTGTA TTAATTTTTC AAAGCTTTGT CATCATTTGC 
AACAACCTAA GATTCTTAAC ATGTTCAAGT GTTCCTCTGA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248400.1
CDS	2..1546
Translation	MMSWGAGERMDRGKAGMARTPGPALLCPGGGKAQLSSASPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCGALAGSIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGEYQGRILFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLMKGPDSLIDGGNETVAAVCIAATGKPVARIDWEGDLGEMESTITSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGEWPDGLLASDNTLHFVHPLTFNYSGVYVCKVTNSLGQRSDQKVIYISDIPLKQTSSIAVAGAVIGAVLALFIIAVFVTVLLTPRKKRPSYLDKVYVFLKTLKSPELASKRLPSCGGAHLPERLEQDQKLKVGLGYTVSSRPAWATGNPTAKFEVNKFFKNPMPFVLIFQSFVIICNNLRFLTCSSVPLK

Target ORF information:

RefSeq Version	XM_006248338.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nectin cell adhesion molecule 3 (Nectin3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248338.3

ORF Insert Sequence:

ATGATGTCCT GGGGCGCGGG CGAGCGGATG GACCGGGGCA AGGCGGGCAT GGCGCGGACC 
CCGGGCCCGG CCCTGTTGTG TCCTGGAGGC GGCAAAGCAC AACTTTCCTC GGCGTCTCCT 
CCCGCGGCCG GACTCCTGCT GCCGGCCCCG ACGCCGCCGC CGCTGCTGCT GCTGCTCATT 
CCCCTGCTTC TCTTCTCCCG GCTCTGTGGT GCCTTAGCTG GATCAATTAT TGTGGAGCCG 
CATGTCACAG CAGTGTGGGG AAAGAATGTG TCCTTGAAGT GTTTAATTGA AGTGAATGAG 
ACTATCACAC AGATCTCATG GGAGAAGATA CACGGCAAGA GCACACAGAC CGTTGCGGTG 
CATCATCCTC AGTATGGATT CTCTGTTCAG GGAGAGTATC AGGGAAGAAT CTTGTTTAAA 
AACTATTCAC TTAATGATGC AACAATTACT CTGCATAACA TAGGCTTCTC AGATTCTGGA 
AAATACATAT GCAAAGCTGT CACATTCCCA CTTGGAAATG CCCAGTCCTC TACAACTGTG 
ACTGTGCTAG TTGAACCCAC CGTGAGCCTG ATGAAAGGGC CAGACTCTTT AATTGATGGA 
GGAAATGAGA CCGTAGCAGC CGTTTGTATA GCGGCCACTG GAAAACCAGT TGCACGTATT 
GACTGGGAAG GGGATCTCGG CGAAATGGAA TCTACTATAA CTTCTTTTCC CAATGAAACA 
GCAACGATTA TCAGCCAATA CAAGCTGTTT CCCACAAGAT TTGCTAGAGG AAGGCGAATT 
ACTTGTGTTG TAAAACATCC AGCCTTAGAA AAGGACATTC GATACTCTTT CATACTCGAC 
ATCCAGTATG CTCCTGAAGT CTCAGTGACA GGATATGATG GAAATTGGTT TGTGGGAAGA 
AAAGGTGTTA ACCTCAAGTG TAATGCTGAC GCAAATCCTC CACCCTTCAA GTCTGTGTGG 
AGCAGGTTGG ATGGAGAATG GCCTGATGGT TTATTGGCGT CAGACAATAC TCTTCATTTT 
GTTCATCCAC TGACTTTCAA TTATTCTGGT GTTTATGTCT GTAAAGTGAC AAATTCCCTT 
GGTCAAAGAA GTGATCAAAA GGTCATCTAC ATTTCAGACA TCCCGCTTAA GCAGACCTCA 
TCCATAGCAG TGGCTGGAGC TGTGATTGGA GCTGTCCTGG CCCTCTTCAT CATCGCTGTC 
TTTGTGACTG TGTTGCTGAC ACCTCGGAAA AAGAGACCAT CCTATCTTGA CAAAGTGTAT 
GTGTTCCTGA AGACACTTAA ATCACCTGAA CTAGCTTCTA AACGTCTGCC CAGCTGTGGC 
GGCGCACATC TACCTGAGAG GCTGGAGCAG GACCAGAAGC TTAAAGTCGG CCTTGGCTAC 
ACAGTGAGTT CGAGGCCTGC CTGGGCTACT GGAAACCCCA CTGCAAAATT TGAAGTGAAT 
AAATTTTTTA AAAATCCTAT GCCATTTGTA TTAATTTTTC AAAGCTTTGT CATCATTTGC 
AACAACCTAA GATTCTTAAC ATGTTCAAGT GTTCCTCTGA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High Resolution Localization of Rab5, EEA1, and Nectin-3 to Tubulobulbar Complexes in the Rat Testis.
Anatomical record (Hoboken, N.J. : 2007)300(6)1160-1170(2017 Jun)
Adams A,Wayne Vogl A

Nectin-3 Is Increased in the Cell Junctions of the Uterine Epithelium at Implantation.
Reproductive sciences (Thousand Oaks, Calif.)23(11)1580-1592(2016 11)
Poon CE,Madawala RJ,Dowland SN,Murphy CR

PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.
The Journal of biological chemistry291(21)11016-29(2016 May)
Guerrera D,Shah J,Vasileva E,Sluysmans S,M?an I,Jond L,Poser I,Mann M,Hyman AA,Citi S

Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations.
Nature communications54995(2014 Sep)
van der Kooij MA,Fantin M,Rejmak E,Grosse J,Zanoletti O,Fournier C,Ganguly K,Kalita K,Kaczmarek L,Sandi C

Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.
The Journal of biological chemistry288(41)29356-68(2013 Oct)
Kurita S,Yamada T,Rikitsu E,Ikeda W,Takai Y

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Nectin3 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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