Gene Symbol | Hdac1 |
Entrez Gene ID | 297893 |
Full Name | histone deacetylase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Hdac1 cDNA ORF clone
Gene Symbol | Hdac1 |
Entrez Gene ID | 297893 |
Full Name | histone deacetylase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001025409.1 | NP_001020580.1 | histone deacetylase 1 |
LOC708441 | XP_001096929.2 | |
Canis lupus familiaris (dog) | HDAC1 | XP_544435.2 |
Kluyveromyces lactis | KLLA0E01981g | XP_454037.1 |
Oryza sativa (rice) | Os02g0214900 | NP_001046284.1 |
Xenopus tropicalis (tropical clawed frog) | hdac1 | NP_001025564.1 |
Pan troglodytes (chimpanzee) | HDAC1 | XP_519834.2 |
Pan troglodytes (chimpanzee) | HDAC1 | XP_001163573.2 |
Mus musculus (house mouse) | Hdac1 | NP_032254.1 |
Rattus norvegicus (Norway rat) | Hdac1 | NP_001020580.1 |
Caenorhabditis elegans (roundworm) | hda-3 | NP_493026.1 |
Eremothecium gossypii | AGOS_AGR395W | NP_987061.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_05857 | XP_003711681.1 |
Arabidopsis thaliana (thale cress) | HD1 | NP_195526.1 |
Homo sapiens (human) | HDAC1 | NP_004955.2 |
Neurospora crassa | NCU00824 | XP_964367.1 |
Oryza sativa (rice) | Os06g0583400 | NP_001057943.1 |
Drosophila melanogaster (fruit fly) | Rpd3 | NP_647918.2 |
Saccharomyces cerevisiae (baker's yeast) | RPD3 | NP_014069.1 |
Schizosaccharomyces pombe (fission yeast) | clr6 | NP_595333.1 |
Bos taurus (cattle) | HDAC1 | NP_001032521.1 |
Gallus gallus (chicken) | HDAC1 | NP_989487.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006511 | XP_316539.2 |
Histone Deacetylase 1 Inhibition Protects Against Hypoxia-Induced Swelling in H9c2 Cardiomyocytes Through Regulating Cell Stiffness.
Li Y, Zhang Z, Zhou X, Li R, Cheng Y, Shang B, Han Y, Liu B, Xie X
Circulation journal : official journal of the Japanese Circulation Society82(1)192-202(2017 Dec)
HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins.
Cai RL, Yan-Neale Y, Cueto MA, Xu H, Cohen D
The Journal of biological chemistry275(36)27909-16(2000 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Co-regulation of H3K9ac by HDAC1 and HDAC3 is important development of the pathophysiology of a schizophrenia-like phenotype.
Title: HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals.
Resveratrol restores the antinociceptive effect of morphine by reversing morphine infusion-induced spinal cord neuroinflammation and increase in TNFR1 expression. The reversal of the morphine-induced increase in TNFR1 expression by resveratrol is partially due to reversal of the morphine infusion-induced increase in HDAC1 expression.
Title: Resveratrol reverses morphine-induced neuroinflammation in morphine-tolerant rats by reversal HDAC1 expression.
In conclusion, this study demonstrates that HDAC inhibitors affect oval cells by suppressing AKT/mTOR signaling.
Title: Histone deacetylase inhibitors reduce WB-F344 oval cell viability and migration capability by suppressing AKT/mTOR signaling in?vitro.
nuclear Hdac1 may control intestinal epithelial cell metabolism by regulating the supply of acetyl groups
Title: Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells.
Suggest that HDAC1 played an important role in carcinogenesis of pancreaticobiliary maljunction through the regulation of COX-2.
Title: Carcinogenic Potential of Biliary Epithelium of Congenital Choledochal Cyst Model in Rats: A Special Reference to HDAC Expression.
The following Hdac1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hdac1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13308 | |
Clone ID Related Accession (Same CDS sequence) | NM_001025409.1 | |
Accession Version | NM_001025409.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | histone deacetylase 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097943.1. On Jul 15, 2005 this sequence version replaced XM_216349.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC097943.1, BC107476.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCGCAGA CTCAGGGCAC CAAGAGGAAA GTCTGTTACT ACTACGACGG GGATGTTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001020580.1 |
CDS | 19..1467 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001025409.1 |
1 | ATGGCGCAGA CTCAGGGCAC CAAGAGGAAA GTCTGTTACT ACTACGACGG GGATGTTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Histone Deacetylase 1 Inhibition Protects Against Hypoxia-Induced Swelling in H9c2 Cardiomyocytes Through Regulating Cell Stiffness. |
HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins. |