Dyrk2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Dyrk2
Entrez Gene ID	314862
Full Name	dual specificity tyrosine phosphorylation regulated kinase 2
General protein information	Preferred Names dual specificity tyrosine phosphorylation regulated kinase 2 Names dual specificity tyrosine-phosphorylation-regulated kinase 2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q22

mRNA and Protein(s)

mRNA	Protein	Name
XM_017594853.1	XP_017450342.1	dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2
NM_001108100.1	NP_001101570.1	dual specificity tyrosine-phosphorylation-regulated kinase 2
XM_006241389.3	XP_006241451.1	dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1
XM_006241391.3	XP_006241453.1	dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DYRK2	XP_001161394.2
Canis lupus familiaris (dog)	DYRK2	XP_005625654.1
Mus musculus (house mouse)	Dyrk2	NP_001014412.1
Xenopus tropicalis (tropical clawed frog)	dyrk2	XP_002937581.2
Drosophila melanogaster (fruit fly)	Dyrk3	NP_001033810.1
Caenorhabditis elegans (roundworm)	mbk-2	NP_001040950.1
Neurospora crassa	NCU06638	XP_960871.1
Rattus norvegicus (Norway rat)	Dyrk2	NP_001101570.1
Gallus gallus (chicken)	DYRK2	NP_001026651.1
Magnaporthe oryzae (rice blast fungus)	MGG_00760	XP_003718240.1
Homo sapiens (human)	DYRK2	NP_006473.2
	DYRK2	XP_001117146.1
Bos taurus (cattle)	DYRK2	XP_002687443.1
Danio rerio (zebrafish)	dyrk2	NP_001038298.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008241	XP_317229.4

Gene Ontology
Bibliography

Related articles in PubMed

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex.
Sharma S, Findlay GM, Bandukwala HS, Oberdoerffer S, Baust B, Li Z, Schmidt V, Hogan PG, Sacks DB, Rao A
Proceedings of the National Academy of Sciences of the United States of America108(28)11381-6(2011 Jul)

ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.
Taira N, Yamamoto H, Yamaguchi T, Miki Y, Yoshida K
The Journal of biological chemistry285(7)4909-19(2010 Feb)

Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.
Maddika S, Chen J
Nature cell biology11(4)409-19(2009 Apr)

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling.
Varjosalo M, Bj?rklund M, Cheng F, Syv?nen H, Kivioja T, Kilpinen S, Sun Z, Kallioniemi O, Stunnenberg HG, He WW, Ojala P, Taipale J
Cell133(3)537-48(2008 May)

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.
Taira N, Nihira K, Yamaguchi T, Miki Y, Yoshida K
Molecular cell25(5)725-38(2007 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dyrk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dyrk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06680	NM_001108100.1 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa06680	XM_006241391.3 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa06680	XM_017594853.1 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa30149	XM_006241389.3 Latest version!	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dyrk2 ( NM_001108100.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101570.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), mRNA.

Price & Availability↑

CloneID	ORa06680
Clone ID Related Accession (Same CDS sequence)	XM_017594853.1 , NM_001108100.1 , XM_006241391.3
Accession Version	NM_001108100.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473960.2. On or before Oct 4, 2007 this sequence version replaced XM_001081013.1, XM_235179.4. ##Evidence-Data-START## CDS exon combination :: EV777972.1, DN931003.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAATGACC ACCTCCACAT CAGCCACAGC CACGGACAGA TCCAGGTTCA GCAGCTGTTC 
GAGGACAACA GTAACAAAAG GACAGTGCTC ACAACCCAAC CCAATGGGCT TACGACGGTG 
GGCAAGACGG GCTTGCCTGT GGTGCCTGAG CGGCAGCTGG AGAGCATTCA CAGACGGCAG 
GGGAGTTCCA CCTCTCTGAA GTCCATGGAA GGCATGGGGA AGGTAAAAGC CAGCCCCATG 
ACACCTGAAC AAGCGATGAA GCAATACATT CAAAAACTCA CAGCCTTCGA ACACCACGAG 
ATTTTCAGCT ACCCCGAAAT CTACTTCTTG GGTCCAAATG CAAAGAAGCG CCAAGGCATG 
ACAGGTGGAC CCAACAATGG CGGTTATGAT GACGACCAGG GATCATACGT GCAGGTGCCC 
CACGATCACG TGGCTTACAG GTACGAGGTC CTCAAAGTCA TCGGGAAGGG GAGCTTTGGG 
CAGGTGGTCA AGGCCTATGA CCACAAAGTC CACCAGCACG TGGCCCTGAA GATGGTGCGG 
AACGAGAAGC GCTTCCACCG GCAGGCGGCA GAGGAGATCC GGATCTTGGA ACACCTACGG 
AAGCAGGACA AGGACAACAC CATGAACGTC ATTCACATGC TGGAGAACTT CACCTTCCGC 
AACCATATCT GCATGACGTT CGAGCTGCTG AGCATGAACC TCTATGAGCT CATCAAGAAG 
AATAAGTTCC AAGGCTTCAG CCTGCCTCTG GTGCGCAAGT TCGCCCACTC CATTCTGCAG 
TGCTTGGATG CTTTGCACAA AAACAGAATA ATCCACTGTG ACCTTAAGCC CGAGAACATT 
TTGTTAAAGC AGCAGGGTCG GAGCAGTATT AAAGTGATTG ACTTTGGCTC CAGTTGTTAT 
GAGCACCAGC GCGTCTACAC GTACATCCAG TCGCGCTTTT ACCGGGCTCC GGAAGTGATC 
CTTGGAGCCA GGTATGGCAT GCCCATTGAC ATGTGGAGCC TGGGTTGCAT CCTCGCGGAA 
CTTCTGACGG GTTACCCCCT CTTGCCTGGG GAGGATGAAG GGGACCAGCT AGCTTGTATG 
ATCGAGCTTT TGGGCATGCC CTCTCAAAAA CTCCTGGATG CTTCCAAACG AGCCAAAAAT 
TTCGTGAGCT CTAAGGGTTA CCCCCGATAC TGCACTGTTA CAACTCTTTC GGATGGCTCT 
GTGGTACTCA ACGGAGGCAG ATCCCGGAGA GGGAAACTGA GGGGTCCGCC AGAGAGCAGA 
GAGTGGGGGA ATGCACTGAA GGGATGTGAT GATCCTCTTT TCCTTGACTT CTTAAAACAG 
TGTTTGGAGT GGGATCCCGC GGTCCGAATG ACCCCGGGAC AGGCTCTACG GCACCCGTGG 
CTTAGGAGGC GTTTGCCAAA GCCTCCGACC GGGGAGAAGA CTGCGGTGAA GAGGGTCACA 
GAGAGTACTG GTGCTATCAC CTCCATTTCC AAGTTACCTC CACCTTCCAG CTCAGCTTCC 
AAGCTGAGGA CTAATTTGGC ACAGATGACA GATGCCAATG GGAATATTCA GCAGAGGACA 
GTGTTGCCGA AACTCGTTAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101570.1
CDS	81..1664
Translation	MNDHLHISHSHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLESIHRRQGSSTSLKSMEGMGKVKASPMTPEQAMKQYIQKLTAFEHHEIFSYPEIYFLGPNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSSIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTAVKRVTESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS

Target ORF information:

RefSeq Version	NM_001108100.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108100.1

ORF Insert Sequence:

ATGAATGACC ACCTCCACAT CAGCCACAGC CACGGACAGA TCCAGGTTCA GCAGCTGTTC 
GAGGACAACA GTAACAAAAG GACAGTGCTC ACAACCCAAC CCAATGGGCT TACGACGGTG 
GGCAAGACGG GCTTGCCTGT GGTGCCTGAG CGGCAGCTGG AGAGCATTCA CAGACGGCAG 
GGGAGTTCCA CCTCTCTGAA GTCCATGGAA GGCATGGGGA AGGTAAAAGC CAGCCCCATG 
ACACCTGAAC AAGCGATGAA GCAATACATT CAAAAACTCA CAGCCTTCGA ACACCACGAG 
ATTTTCAGCT ACCCCGAAAT CTACTTCTTG GGTCCAAATG CAAAGAAGCG CCAAGGCATG 
ACAGGTGGAC CCAACAATGG CGGTTATGAT GACGACCAGG GATCATACGT GCAGGTGCCC 
CACGATCACG TGGCTTACAG GTACGAGGTC CTCAAAGTCA TCGGGAAGGG GAGCTTTGGG 
CAGGTGGTCA AGGCCTATGA CCACAAAGTC CACCAGCACG TGGCCCTGAA GATGGTGCGG 
AACGAGAAGC GCTTCCACCG GCAGGCGGCA GAGGAGATCC GGATCTTGGA ACACCTACGG 
AAGCAGGACA AGGACAACAC CATGAACGTC ATTCACATGC TGGAGAACTT CACCTTCCGC 
AACCATATCT GCATGACGTT CGAGCTGCTG AGCATGAACC TCTATGAGCT CATCAAGAAG 
AATAAGTTCC AAGGCTTCAG CCTGCCTCTG GTGCGCAAGT TCGCCCACTC CATTCTGCAG 
TGCTTGGATG CTTTGCACAA AAACAGAATA ATCCACTGTG ACCTTAAGCC CGAGAACATT 
TTGTTAAAGC AGCAGGGTCG GAGCAGTATT AAAGTGATTG ACTTTGGCTC CAGTTGTTAT 
GAGCACCAGC GCGTCTACAC GTACATCCAG TCGCGCTTTT ACCGGGCTCC GGAAGTGATC 
CTTGGAGCCA GGTATGGCAT GCCCATTGAC ATGTGGAGCC TGGGTTGCAT CCTCGCGGAA 
CTTCTGACGG GTTACCCCCT CTTGCCTGGG GAGGATGAAG GGGACCAGCT AGCTTGTATG 
ATCGAGCTTT TGGGCATGCC CTCTCAAAAA CTCCTGGATG CTTCCAAACG AGCCAAAAAT 
TTCGTGAGCT CTAAGGGTTA CCCCCGATAC TGCACTGTTA CAACTCTTTC GGATGGCTCT 
GTGGTACTCA ACGGAGGCAG ATCCCGGAGA GGGAAACTGA GGGGTCCGCC AGAGAGCAGA 
GAGTGGGGGA ATGCACTGAA GGGATGTGAT GATCCTCTTT TCCTTGACTT CTTAAAACAG 
TGTTTGGAGT GGGATCCCGC GGTCCGAATG ACCCCGGGAC AGGCTCTACG GCACCCGTGG 
CTTAGGAGGC GTTTGCCAAA GCCTCCGACC GGGGAGAAGA CTGCGGTGAA GAGGGTCACA 
GAGAGTACTG GTGCTATCAC CTCCATTTCC AAGTTACCTC CACCTTCCAG CTCAGCTTCC 
AAGCTGAGGA CTAATTTGGC ACAGATGACA GATGCCAATG GGAATATTCA GCAGAGGACA 
GTGTTGCCGA AACTCGTTAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk2 ( XM_017594853.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450342.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa06680
Clone ID Related Accession (Same CDS sequence)	XM_017594853.1 , NM_001108100.1 , XM_006241391.3
Accession Version	XM_017594853.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGACC ACCTCCACAT CAGCCACAGC CACGGACAGA TCCAGGTTCA GCAGCTGTTC 
GAGGACAACA GTAACAAAAG GACAGTGCTC ACAACCCAAC CCAATGGGCT TACGACGGTG 
GGCAAGACGG GCTTGCCTGT GGTGCCTGAG CGGCAGCTGG AGAGCATTCA CAGACGGCAG 
GGGAGTTCCA CCTCTCTGAA GTCCATGGAA GGCATGGGGA AGGTAAAAGC CAGCCCCATG 
ACACCTGAAC AAGCGATGAA GCAATACATT CAAAAACTCA CAGCCTTCGA ACACCACGAG 
ATTTTCAGCT ACCCCGAAAT CTACTTCTTG GGTCCAAATG CAAAGAAGCG CCAAGGCATG 
ACAGGTGGAC CCAACAATGG CGGTTATGAT GACGACCAGG GATCATACGT GCAGGTGCCC 
CACGATCACG TGGCTTACAG GTACGAGGTC CTCAAAGTCA TCGGGAAGGG GAGCTTTGGG 
CAGGTGGTCA AGGCCTATGA CCACAAAGTC CACCAGCACG TGGCCCTGAA GATGGTGCGG 
AACGAGAAGC GCTTCCACCG GCAGGCGGCA GAGGAGATCC GGATCTTGGA ACACCTACGG 
AAGCAGGACA AGGACAACAC CATGAACGTC ATTCACATGC TGGAGAACTT CACCTTCCGC 
AACCATATCT GCATGACGTT CGAGCTGCTG AGCATGAACC TCTATGAGCT CATCAAGAAG 
AATAAGTTCC AAGGCTTCAG CCTGCCTCTG GTGCGCAAGT TCGCCCACTC CATTCTGCAG 
TGCTTGGATG CTTTGCACAA AAACAGAATA ATCCACTGTG ACCTTAAGCC CGAGAACATT 
TTGTTAAAGC AGCAGGGTCG GAGCAGTATT AAAGTGATTG ACTTTGGCTC CAGTTGTTAT 
GAGCACCAGC GCGTCTACAC GTACATCCAG TCGCGCTTTT ACCGGGCTCC GGAAGTGATC 
CTTGGAGCCA GGTATGGCAT GCCCATTGAC ATGTGGAGCC TGGGTTGCAT CCTCGCGGAA 
CTTCTGACGG GTTACCCCCT CTTGCCTGGG GAGGATGAAG GGGACCAGCT AGCTTGTATG 
ATCGAGCTTT TGGGCATGCC CTCTCAAAAA CTCCTGGATG CTTCCAAACG AGCCAAAAAT 
TTCGTGAGCT CTAAGGGTTA CCCCCGATAC TGCACTGTTA CAACTCTTTC GGATGGCTCT 
GTGGTACTCA ACGGAGGCAG ATCCCGGAGA GGGAAACTGA GGGGTCCGCC AGAGAGCAGA 
GAGTGGGGGA ATGCACTGAA GGGATGTGAT GATCCTCTTT TCCTTGACTT CTTAAAACAG 
TGTTTGGAGT GGGATCCCGC GGTCCGAATG ACCCCGGGAC AGGCTCTACG GCACCCGTGG 
CTTAGGAGGC GTTTGCCAAA GCCTCCGACC GGGGAGAAGA CTGCGGTGAA GAGGGTCACA 
GAGAGTACTG GTGCTATCAC CTCCATTTCC AAGTTACCTC CACCTTCCAG CTCAGCTTCC 
AAGCTGAGGA CTAATTTGGC ACAGATGACA GATGCCAATG GGAATATTCA GCAGAGGACA 
GTGTTGCCGA AACTCGTTAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450342.1
CDS	455..2038
Translation	MNDHLHISHSHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLESIHRRQGSSTSLKSMEGMGKVKASPMTPEQAMKQYIQKLTAFEHHEIFSYPEIYFLGPNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSSIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTAVKRVTESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS

Target ORF information:

RefSeq Version	XM_017594853.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594853.1

ORF Insert Sequence:

ATGAATGACC ACCTCCACAT CAGCCACAGC CACGGACAGA TCCAGGTTCA GCAGCTGTTC 
GAGGACAACA GTAACAAAAG GACAGTGCTC ACAACCCAAC CCAATGGGCT TACGACGGTG 
GGCAAGACGG GCTTGCCTGT GGTGCCTGAG CGGCAGCTGG AGAGCATTCA CAGACGGCAG 
GGGAGTTCCA CCTCTCTGAA GTCCATGGAA GGCATGGGGA AGGTAAAAGC CAGCCCCATG 
ACACCTGAAC AAGCGATGAA GCAATACATT CAAAAACTCA CAGCCTTCGA ACACCACGAG 
ATTTTCAGCT ACCCCGAAAT CTACTTCTTG GGTCCAAATG CAAAGAAGCG CCAAGGCATG 
ACAGGTGGAC CCAACAATGG CGGTTATGAT GACGACCAGG GATCATACGT GCAGGTGCCC 
CACGATCACG TGGCTTACAG GTACGAGGTC CTCAAAGTCA TCGGGAAGGG GAGCTTTGGG 
CAGGTGGTCA AGGCCTATGA CCACAAAGTC CACCAGCACG TGGCCCTGAA GATGGTGCGG 
AACGAGAAGC GCTTCCACCG GCAGGCGGCA GAGGAGATCC GGATCTTGGA ACACCTACGG 
AAGCAGGACA AGGACAACAC CATGAACGTC ATTCACATGC TGGAGAACTT CACCTTCCGC 
AACCATATCT GCATGACGTT CGAGCTGCTG AGCATGAACC TCTATGAGCT CATCAAGAAG 
AATAAGTTCC AAGGCTTCAG CCTGCCTCTG GTGCGCAAGT TCGCCCACTC CATTCTGCAG 
TGCTTGGATG CTTTGCACAA AAACAGAATA ATCCACTGTG ACCTTAAGCC CGAGAACATT 
TTGTTAAAGC AGCAGGGTCG GAGCAGTATT AAAGTGATTG ACTTTGGCTC CAGTTGTTAT 
GAGCACCAGC GCGTCTACAC GTACATCCAG TCGCGCTTTT ACCGGGCTCC GGAAGTGATC 
CTTGGAGCCA GGTATGGCAT GCCCATTGAC ATGTGGAGCC TGGGTTGCAT CCTCGCGGAA 
CTTCTGACGG GTTACCCCCT CTTGCCTGGG GAGGATGAAG GGGACCAGCT AGCTTGTATG 
ATCGAGCTTT TGGGCATGCC CTCTCAAAAA CTCCTGGATG CTTCCAAACG AGCCAAAAAT 
TTCGTGAGCT CTAAGGGTTA CCCCCGATAC TGCACTGTTA CAACTCTTTC GGATGGCTCT 
GTGGTACTCA ACGGAGGCAG ATCCCGGAGA GGGAAACTGA GGGGTCCGCC AGAGAGCAGA 
GAGTGGGGGA ATGCACTGAA GGGATGTGAT GATCCTCTTT TCCTTGACTT CTTAAAACAG 
TGTTTGGAGT GGGATCCCGC GGTCCGAATG ACCCCGGGAC AGGCTCTACG GCACCCGTGG 
CTTAGGAGGC GTTTGCCAAA GCCTCCGACC GGGGAGAAGA CTGCGGTGAA GAGGGTCACA 
GAGAGTACTG GTGCTATCAC CTCCATTTCC AAGTTACCTC CACCTTCCAG CTCAGCTTCC 
AAGCTGAGGA CTAATTTGGC ACAGATGACA GATGCCAATG GGAATATTCA GCAGAGGACA 
GTGTTGCCGA AACTCGTTAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk2 ( XM_006241391.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241453.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa06680
Clone ID Related Accession (Same CDS sequence)	XM_017594853.1 , NM_001108100.1 , XM_006241391.3
Accession Version	XM_006241391.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006241391.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGACC ACCTCCACAT CAGCCACAGC CACGGACAGA TCCAGGTTCA GCAGCTGTTC 
GAGGACAACA GTAACAAAAG GACAGTGCTC ACAACCCAAC CCAATGGGCT TACGACGGTG 
GGCAAGACGG GCTTGCCTGT GGTGCCTGAG CGGCAGCTGG AGAGCATTCA CAGACGGCAG 
GGGAGTTCCA CCTCTCTGAA GTCCATGGAA GGCATGGGGA AGGTAAAAGC CAGCCCCATG 
ACACCTGAAC AAGCGATGAA GCAATACATT CAAAAACTCA CAGCCTTCGA ACACCACGAG 
ATTTTCAGCT ACCCCGAAAT CTACTTCTTG GGTCCAAATG CAAAGAAGCG CCAAGGCATG 
ACAGGTGGAC CCAACAATGG CGGTTATGAT GACGACCAGG GATCATACGT GCAGGTGCCC 
CACGATCACG TGGCTTACAG GTACGAGGTC CTCAAAGTCA TCGGGAAGGG GAGCTTTGGG 
CAGGTGGTCA AGGCCTATGA CCACAAAGTC CACCAGCACG TGGCCCTGAA GATGGTGCGG 
AACGAGAAGC GCTTCCACCG GCAGGCGGCA GAGGAGATCC GGATCTTGGA ACACCTACGG 
AAGCAGGACA AGGACAACAC CATGAACGTC ATTCACATGC TGGAGAACTT CACCTTCCGC 
AACCATATCT GCATGACGTT CGAGCTGCTG AGCATGAACC TCTATGAGCT CATCAAGAAG 
AATAAGTTCC AAGGCTTCAG CCTGCCTCTG GTGCGCAAGT TCGCCCACTC CATTCTGCAG 
TGCTTGGATG CTTTGCACAA AAACAGAATA ATCCACTGTG ACCTTAAGCC CGAGAACATT 
TTGTTAAAGC AGCAGGGTCG GAGCAGTATT AAAGTGATTG ACTTTGGCTC CAGTTGTTAT 
GAGCACCAGC GCGTCTACAC GTACATCCAG TCGCGCTTTT ACCGGGCTCC GGAAGTGATC 
CTTGGAGCCA GGTATGGCAT GCCCATTGAC ATGTGGAGCC TGGGTTGCAT CCTCGCGGAA 
CTTCTGACGG GTTACCCCCT CTTGCCTGGG GAGGATGAAG GGGACCAGCT AGCTTGTATG 
ATCGAGCTTT TGGGCATGCC CTCTCAAAAA CTCCTGGATG CTTCCAAACG AGCCAAAAAT 
TTCGTGAGCT CTAAGGGTTA CCCCCGATAC TGCACTGTTA CAACTCTTTC GGATGGCTCT 
GTGGTACTCA ACGGAGGCAG ATCCCGGAGA GGGAAACTGA GGGGTCCGCC AGAGAGCAGA 
GAGTGGGGGA ATGCACTGAA GGGATGTGAT GATCCTCTTT TCCTTGACTT CTTAAAACAG 
TGTTTGGAGT GGGATCCCGC GGTCCGAATG ACCCCGGGAC AGGCTCTACG GCACCCGTGG 
CTTAGGAGGC GTTTGCCAAA GCCTCCGACC GGGGAGAAGA CTGCGGTGAA GAGGGTCACA 
GAGAGTACTG GTGCTATCAC CTCCATTTCC AAGTTACCTC CACCTTCCAG CTCAGCTTCC 
AAGCTGAGGA CTAATTTGGC ACAGATGACA GATGCCAATG GGAATATTCA GCAGAGGACA 
GTGTTGCCGA AACTCGTTAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241453.1
CDS	638..2221
Translation	MNDHLHISHSHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLESIHRRQGSSTSLKSMEGMGKVKASPMTPEQAMKQYIQKLTAFEHHEIFSYPEIYFLGPNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSSIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTAVKRVTESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS

Target ORF information:

RefSeq Version	XM_006241391.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006241391.3

ORF Insert Sequence:

ATGAATGACC ACCTCCACAT CAGCCACAGC CACGGACAGA TCCAGGTTCA GCAGCTGTTC 
GAGGACAACA GTAACAAAAG GACAGTGCTC ACAACCCAAC CCAATGGGCT TACGACGGTG 
GGCAAGACGG GCTTGCCTGT GGTGCCTGAG CGGCAGCTGG AGAGCATTCA CAGACGGCAG 
GGGAGTTCCA CCTCTCTGAA GTCCATGGAA GGCATGGGGA AGGTAAAAGC CAGCCCCATG 
ACACCTGAAC AAGCGATGAA GCAATACATT CAAAAACTCA CAGCCTTCGA ACACCACGAG 
ATTTTCAGCT ACCCCGAAAT CTACTTCTTG GGTCCAAATG CAAAGAAGCG CCAAGGCATG 
ACAGGTGGAC CCAACAATGG CGGTTATGAT GACGACCAGG GATCATACGT GCAGGTGCCC 
CACGATCACG TGGCTTACAG GTACGAGGTC CTCAAAGTCA TCGGGAAGGG GAGCTTTGGG 
CAGGTGGTCA AGGCCTATGA CCACAAAGTC CACCAGCACG TGGCCCTGAA GATGGTGCGG 
AACGAGAAGC GCTTCCACCG GCAGGCGGCA GAGGAGATCC GGATCTTGGA ACACCTACGG 
AAGCAGGACA AGGACAACAC CATGAACGTC ATTCACATGC TGGAGAACTT CACCTTCCGC 
AACCATATCT GCATGACGTT CGAGCTGCTG AGCATGAACC TCTATGAGCT CATCAAGAAG 
AATAAGTTCC AAGGCTTCAG CCTGCCTCTG GTGCGCAAGT TCGCCCACTC CATTCTGCAG 
TGCTTGGATG CTTTGCACAA AAACAGAATA ATCCACTGTG ACCTTAAGCC CGAGAACATT 
TTGTTAAAGC AGCAGGGTCG GAGCAGTATT AAAGTGATTG ACTTTGGCTC CAGTTGTTAT 
GAGCACCAGC GCGTCTACAC GTACATCCAG TCGCGCTTTT ACCGGGCTCC GGAAGTGATC 
CTTGGAGCCA GGTATGGCAT GCCCATTGAC ATGTGGAGCC TGGGTTGCAT CCTCGCGGAA 
CTTCTGACGG GTTACCCCCT CTTGCCTGGG GAGGATGAAG GGGACCAGCT AGCTTGTATG 
ATCGAGCTTT TGGGCATGCC CTCTCAAAAA CTCCTGGATG CTTCCAAACG AGCCAAAAAT 
TTCGTGAGCT CTAAGGGTTA CCCCCGATAC TGCACTGTTA CAACTCTTTC GGATGGCTCT 
GTGGTACTCA ACGGAGGCAG ATCCCGGAGA GGGAAACTGA GGGGTCCGCC AGAGAGCAGA 
GAGTGGGGGA ATGCACTGAA GGGATGTGAT GATCCTCTTT TCCTTGACTT CTTAAAACAG 
TGTTTGGAGT GGGATCCCGC GGTCCGAATG ACCCCGGGAC AGGCTCTACG GCACCCGTGG 
CTTAGGAGGC GTTTGCCAAA GCCTCCGACC GGGGAGAAGA CTGCGGTGAA GAGGGTCACA 
GAGAGTACTG GTGCTATCAC CTCCATTTCC AAGTTACCTC CACCTTCCAG CTCAGCTTCC 
AAGCTGAGGA CTAATTTGGC ACAGATGACA GATGCCAATG GGAATATTCA GCAGAGGACA 
GTGTTGCCGA AACTCGTTAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dyrk2 ( XM_006241389.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241451.1 Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X1, mRNA.

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CloneID	ORa30149
Clone ID Related Accession (Same CDS sequence)	XM_006241389.3
Accession Version	XM_006241389.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006241389.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTTCGA GGCAACAACA GATTGGCGGC GGTAAGCACA CCATGAATGA CCACCTCCAC 
ATCAGCCACA GCCACGGACA GATCCAGGTT CAGCAGCTGT TCGAGGACAA CAGTAACAAA 
AGGACAGTGC TCACAACCCA ACCCAATGGG CTTACGACGG TGGGCAAGAC GGGCTTGCCT 
GTGGTGCCTG AGCGGCAGCT GGAGAGCATT CACAGACGGC AGGGGAGTTC CACCTCTCTG 
AAGTCCATGG AAGGCATGGG GAAGGTAAAA GCCAGCCCCA TGACACCTGA ACAAGCGATG 
AAGCAATACA TTCAAAAACT CACAGCCTTC GAACACCACG AGATTTTCAG CTACCCCGAA 
ATCTACTTCT TGGGTCCAAA TGCAAAGAAG CGCCAAGGCA TGACAGGTGG ACCCAACAAT 
GGCGGTTATG ATGACGACCA GGGATCATAC GTGCAGGTGC CCCACGATCA CGTGGCTTAC 
AGGTACGAGG TCCTCAAAGT CATCGGGAAG GGGAGCTTTG GGCAGGTGGT CAAGGCCTAT 
GACCACAAAG TCCACCAGCA CGTGGCCCTG AAGATGGTGC GGAACGAGAA GCGCTTCCAC 
CGGCAGGCGG CAGAGGAGAT CCGGATCTTG GAACACCTAC GGAAGCAGGA CAAGGACAAC 
ACCATGAACG TCATTCACAT GCTGGAGAAC TTCACCTTCC GCAACCATAT CTGCATGACG 
TTCGAGCTGC TGAGCATGAA CCTCTATGAG CTCATCAAGA AGAATAAGTT CCAAGGCTTC 
AGCCTGCCTC TGGTGCGCAA GTTCGCCCAC TCCATTCTGC AGTGCTTGGA TGCTTTGCAC 
AAAAACAGAA TAATCCACTG TGACCTTAAG CCCGAGAACA TTTTGTTAAA GCAGCAGGGT 
CGGAGCAGTA TTAAAGTGAT TGACTTTGGC TCCAGTTGTT ATGAGCACCA GCGCGTCTAC 
ACGTACATCC AGTCGCGCTT TTACCGGGCT CCGGAAGTGA TCCTTGGAGC CAGGTATGGC 
ATGCCCATTG ACATGTGGAG CCTGGGTTGC ATCCTCGCGG AACTTCTGAC GGGTTACCCC 
CTCTTGCCTG GGGAGGATGA AGGGGACCAG CTAGCTTGTA TGATCGAGCT TTTGGGCATG 
CCCTCTCAAA AACTCCTGGA TGCTTCCAAA CGAGCCAAAA ATTTCGTGAG CTCTAAGGGT 
TACCCCCGAT ACTGCACTGT TACAACTCTT TCGGATGGCT CTGTGGTACT CAACGGAGGC 
AGATCCCGGA GAGGGAAACT GAGGGGTCCG CCAGAGAGCA GAGAGTGGGG GAATGCACTG 
AAGGGATGTG ATGATCCTCT TTTCCTTGAC TTCTTAAAAC AGTGTTTGGA GTGGGATCCC 
GCGGTCCGAA TGACCCCGGG ACAGGCTCTA CGGCACCCGT GGCTTAGGAG GCGTTTGCCA 
AAGCCTCCGA CCGGGGAGAA GACTGCGGTG AAGAGGGTCA CAGAGAGTAC TGGTGCTATC 
ACCTCCATTT CCAAGTTACC TCCACCTTCC AGCTCAGCTT CCAAGCTGAG GACTAATTTG 
GCACAGATGA CAGATGCCAA TGGGAATATT CAGCAGAGGA CAGTGTTGCC GAAACTCGTT 
AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241451.1
CDS	264..1889
Translation	MFSRQQQIGGGKHTMNDHLHISHSHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLESIHRRQGSSTSLKSMEGMGKVKASPMTPEQAMKQYIQKLTAFEHHEIFSYPEIYFLGPNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSSIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTAVKRVTESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS

Target ORF information:

RefSeq Version	XM_006241389.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006241389.3

ORF Insert Sequence:

ATGTTTTCGA GGCAACAACA GATTGGCGGC GGTAAGCACA CCATGAATGA CCACCTCCAC 
ATCAGCCACA GCCACGGACA GATCCAGGTT CAGCAGCTGT TCGAGGACAA CAGTAACAAA 
AGGACAGTGC TCACAACCCA ACCCAATGGG CTTACGACGG TGGGCAAGAC GGGCTTGCCT 
GTGGTGCCTG AGCGGCAGCT GGAGAGCATT CACAGACGGC AGGGGAGTTC CACCTCTCTG 
AAGTCCATGG AAGGCATGGG GAAGGTAAAA GCCAGCCCCA TGACACCTGA ACAAGCGATG 
AAGCAATACA TTCAAAAACT CACAGCCTTC GAACACCACG AGATTTTCAG CTACCCCGAA 
ATCTACTTCT TGGGTCCAAA TGCAAAGAAG CGCCAAGGCA TGACAGGTGG ACCCAACAAT 
GGCGGTTATG ATGACGACCA GGGATCATAC GTGCAGGTGC CCCACGATCA CGTGGCTTAC 
AGGTACGAGG TCCTCAAAGT CATCGGGAAG GGGAGCTTTG GGCAGGTGGT CAAGGCCTAT 
GACCACAAAG TCCACCAGCA CGTGGCCCTG AAGATGGTGC GGAACGAGAA GCGCTTCCAC 
CGGCAGGCGG CAGAGGAGAT CCGGATCTTG GAACACCTAC GGAAGCAGGA CAAGGACAAC 
ACCATGAACG TCATTCACAT GCTGGAGAAC TTCACCTTCC GCAACCATAT CTGCATGACG 
TTCGAGCTGC TGAGCATGAA CCTCTATGAG CTCATCAAGA AGAATAAGTT CCAAGGCTTC 
AGCCTGCCTC TGGTGCGCAA GTTCGCCCAC TCCATTCTGC AGTGCTTGGA TGCTTTGCAC 
AAAAACAGAA TAATCCACTG TGACCTTAAG CCCGAGAACA TTTTGTTAAA GCAGCAGGGT 
CGGAGCAGTA TTAAAGTGAT TGACTTTGGC TCCAGTTGTT ATGAGCACCA GCGCGTCTAC 
ACGTACATCC AGTCGCGCTT TTACCGGGCT CCGGAAGTGA TCCTTGGAGC CAGGTATGGC 
ATGCCCATTG ACATGTGGAG CCTGGGTTGC ATCCTCGCGG AACTTCTGAC GGGTTACCCC 
CTCTTGCCTG GGGAGGATGA AGGGGACCAG CTAGCTTGTA TGATCGAGCT TTTGGGCATG 
CCCTCTCAAA AACTCCTGGA TGCTTCCAAA CGAGCCAAAA ATTTCGTGAG CTCTAAGGGT 
TACCCCCGAT ACTGCACTGT TACAACTCTT TCGGATGGCT CTGTGGTACT CAACGGAGGC 
AGATCCCGGA GAGGGAAACT GAGGGGTCCG CCAGAGAGCA GAGAGTGGGG GAATGCACTG 
AAGGGATGTG ATGATCCTCT TTTCCTTGAC TTCTTAAAAC AGTGTTTGGA GTGGGATCCC 
GCGGTCCGAA TGACCCCGGG ACAGGCTCTA CGGCACCCGT GGCTTAGGAG GCGTTTGCCA 
AAGCCTCCGA CCGGGGAGAA GACTGCGGTG AAGAGGGTCA CAGAGAGTAC TGGTGCTATC 
ACCTCCATTT CCAAGTTACC TCCACCTTCC AGCTCAGCTT CCAAGCTGAG GACTAATTTG 
GCACAGATGA CAGATGCCAA TGGGAATATT CAGCAGAGGA CAGTGTTGCC GAAACTCGTT 
AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex.
Proceedings of the National Academy of Sciences of the United States of America108(28)11381-6(2011 Jul)
Sharma S,Findlay GM,Bandukwala HS,Oberdoerffer S,Baust B,Li Z,Schmidt V,Hogan PG,Sacks DB,Rao A

ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.
The Journal of biological chemistry285(7)4909-19(2010 Feb)
Taira N,Yamamoto H,Yamaguchi T,Miki Y,Yoshida K

Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.
Nature cell biology11(4)409-19(2009 Apr)
Maddika S,Chen J

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling.
Cell133(3)537-48(2008 May)
Varjosalo M,Bj?rklund M,Cheng F,Syv?nen H,Kivioja T,Kilpinen S,Sun Z,Kallioniemi O,Stunnenberg HG,He WW,Ojala P,Taipale J

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.
Molecular cell25(5)725-38(2007 Mar)
Taira N,Nihira K,Yamaguchi T,Miki Y,Yoshida K

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Dyrk2 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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