| Gene Symbol | Dyrk2 |
| Entrez Gene ID | 69181 |
| Full Name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| Synonyms | 1810038L18Rik |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
The following Dyrk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dyrk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu11398 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001014390.2 | |
| Accession Version | NM_001014390.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1800bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-02 | |
| Organism | Mus musculus(house mouse) | |
| Product | dual specificity tyrosine-phosphorylation-regulated kinase 2 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC154039.17. On Nov 17, 2006 this sequence version replaced NM_001014390.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC085145.1, AK149371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTTAACCA GGAAACCTTC GGCCGCCGCT CCCGCCGCCT ACCCGACCGG CCGAGGAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001014412.1 |
| CDS | 135..1934 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001014390.2 |
1 | ATGTTAACCA GGAAACCTTC GGCCGCCGCT CCCGCCGCCT ACCCGACCGG CCGAGGAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu44764 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006514046.3 | |
| Accession Version | XM_006514046.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006514046.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGAGGTG TCTCTGATGT TTATTTTTGC CTAGCAACCC ACAGCCAACT GCTACCTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006514109.1 |
| CDS | 166..2163 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006514046.3 |
1 | ATGGGAGGTG TCTCTGATGT TTATTTTTGC CTAGCAACCC ACAGCCAACT GCTACCTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu70397 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011243552.2 | |
| Accession Version | XM_011243552.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011243552.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAATGACC ACCTCCACCT CAACAGCCAC GGACAGATCC AGGTTCAGCA GCTGTTCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011241854.1 |
| CDS | 157..1737 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011243552.2 |
1 | ATGAATGACC ACCTCCACCT CAACAGCCAC GGACAGATCC AGGTTCAGCA GCTGTTCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu85507 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006514046.4 | |
| Accession Version | XM_006514046.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1839bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006514046.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAAGGTGG AAGGGCAGCC CCTTCCTTCG TCCATGCTTG GGTCACCAGG CTCAGCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006514109.2 |
| CDS | 104..1942 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006514046.4 |
1 | ATGAAGGTGG AAGGGCAGCC CCTTCCTTCG TCCATGCTTG GGTCACCAGG CTCAGCCGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Dual-specificity tyrosine phosphorylation-regulated kinase 2 regulates osteoclast fusion in a cell heterotypic manner. |
DYRK2 negatively regulates cardiomyocyte growth by mediating repressor function of GSK-3? on eIF2B?. |
DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells. |
Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. |
DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1. |
