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Fbxw5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Fbxw5
Entrez Gene ID 362081
Full Name F-box and WD repeat domain containing 5
General protein information
Preferred Names

F-box and WD repeat domain containing 5

Names

F-box/WD repeat-containing protein 5
F-box and WD-40 domain protein 5
F-box and WD-40 domain-containing protein 5
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

3

3p13

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006233623.2 XP_006233685.1 F-box/WD repeat-containing protein 5 isoform X1
XM_006233626.3 XP_006233688.1 F-box/WD repeat-containing protein 5 isoform X2
XM_006233628.3 XP_006233690.1 F-box/WD repeat-containing protein 5 isoform X3
NM_001025730.2 NP_001020901.1 F-box/WD repeat-containing protein 5
XM_006233624.3 XP_006233686.1 F-box/WD repeat-containing protein 5 isoform X2
XM_006233625.2 XP_006233687.1 F-box/WD repeat-containing protein 5 isoform X2
XM_006233627.2 XP_006233689.1 F-box/WD repeat-containing protein 5 isoform X2

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) FBXW5 XP_005625126.1
Rattus norvegicus (Norway rat) Fbxw5 NP_001020901.1
Pan troglodytes (chimpanzee) FBXW5 XP_003312463.1
Gallus gallus (chicken) FBXW5 NP_001025865.1
Mus musculus (house mouse) Fbxw5 NP_038936.1
Danio rerio (zebrafish) fbxw5 NP_998484.1
Drosophila melanogaster (fruit fly) Fbw5 NP_608989.1
Homo sapiens (human) FBXW5 NP_061871.1
Bos taurus (cattle) FBXW5 NP_001179398.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP010041 XP_319186.4

Gene Ontology


Bibliography

Related articles in PubMed

Tnfaip8?l1/Oxi-? binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.
Ha JY, Kim JS, Kang YH, Bok E, Kim YS, Son JH
Journal of neurochemistry129(3)527-38(2014 May)

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression.
Werner A, Disanza A, Reifenberger N, Habeck G, Becker J, Calabrese M, Urlaub H, Lorenz H, Schulman B, Scita G, Melchior F
Nature cell biology15(2)179-88(2013 Feb)

The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication.
Puklowski A, Homsi Y, Keller D, May M, Chauhan S, Kossatz U, Gr?nwald V, Kubicka S, Pich A, Manns MP, Hoffmann I, G?nczy P, Malek NP
Nature cell biology13(8)1004-9(2011 Jul)

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
Ebstein F, Lange N, Urban S, Seifert U, Kr?ger E, Kloetzel PM
The international journal of biochemistry & cell biology41(5)1205-15(2009 May)

WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y
Genes & development22(7)866-71(2008 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

oxidative stress induces Tnfaip8 l1/Oxi-beta, which results in increased autophagy by its exclusive binding with FBXW5 to stabilize TSC2
Title: Tnfaip8?l1/Oxi-? binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.

The following Fbxw5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbxw5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa07624 NM_001025730.2
Latest version!		 Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
ORa07624 XM_006233627.2
Latest version!		 Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
ORa07624 XM_006233626.3
Latest version!		 Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
ORa07624 XM_006233625.2
Latest version!		 Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
ORa07624 XM_006233624.3
Latest version!		 Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $307.30
$439.00
ORa25467 XM_006233628.3
Latest version!		 Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
ORa25466 XM_006233623.2
Latest version!		 Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone 40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa07624
Clone ID Related Accession (Same CDS sequence) XM_006233626.3 , NM_001025730.2 , XM_006233624.3 , XM_006233625.2 , XM_006233627.2
Accession Version NM_001025730.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1710bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-26
Organism Rattus norvegicus(Norway rat)
Product F-box/WD repeat-containing protein 5
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099179.1. On Aug 31, 2012 this sequence version replaced NM_001025730.1. ##Evidence-Data-START## Transcript exon combination :: BC099179.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001020901.1
CDS129..1838
Translation

Target ORF information:

RefSeq Version NM_001025730.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001025730.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa07624
Clone ID Related Accession (Same CDS sequence) XM_006233626.3 , NM_001025730.2 , XM_006233624.3 , XM_006233625.2 , XM_006233627.2
Accession Version XM_006233626.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1710bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product F-box/WD repeat-containing protein 5 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233626.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006233688.1
CDS112..1821
Translation

Target ORF information:

RefSeq Version XM_006233626.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006233626.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa07624
Clone ID Related Accession (Same CDS sequence) XM_006233626.3 , NM_001025730.2 , XM_006233624.3 , XM_006233625.2 , XM_006233627.2
Accession Version XM_006233624.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1710bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product F-box/WD repeat-containing protein 5 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233624.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006233686.1
CDS221..1930
Translation

Target ORF information:

RefSeq Version XM_006233624.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006233624.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa07624
Clone ID Related Accession (Same CDS sequence) XM_006233626.3 , NM_001025730.2 , XM_006233624.3 , XM_006233625.2 , XM_006233627.2
Accession Version XM_006233625.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1710bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product F-box/WD repeat-containing protein 5 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006233625.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006233687.1
CDS433..2142
Translation

Target ORF information:

RefSeq Version XM_006233625.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006233625.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa07624
Clone ID Related Accession (Same CDS sequence) XM_006233626.3 , NM_001025730.2 , XM_006233624.3 , XM_006233625.2 , XM_006233627.2
Accession Version XM_006233627.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1710bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product F-box/WD repeat-containing protein 5 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006233627.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006233689.1
CDS329..2038
Translation

Target ORF information:

RefSeq Version XM_006233627.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006233627.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGATGAGG GGGGCATGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
TTGGGCCCTG CAGATGTGCT GGCTGCTGGG CTGGTGTGCC GCCAGTGGCA GGCTGTCTCC 
CGGGACGAGT TCCTATGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC TCGCGATGTG 
CCCCGCCACC CAGCGGCCAC ATCCTGGTAT GAGGAGTTCC GGCGGCTCTA TGACATGGTG 
CCCTGTGTGG AGGTGCAGAC ACTGAAGGAG CACACCGACC AGGTCCTGCA CCTCAGCTTC 
TCCCACTCGG GGTACCAGTT TGCCTCCTGC TCCAAGGACT GCACAGTGAA GATCTGGAAC 
AATGACCTGA CCATCTCTCT GCTGCACAGT GCAGATATGA GGCCATACAA CTGGAGTTAC 
ACCCAGTTCT CCCAGTTCAA CCAGGATGAC TCACTGTTGC TGGCCTCGGG GGTGTTCCTA 
GGGCCACATA ACTCCTCCTC AGGCGAGATA GCTGTCATCA GCTTAGACTC CTTCGCCCTG 
CTGTCGCGTG TGCGAAACAA GCCCTATGAT GTGTTTGGCT GCTGGCTCAC AGAAACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATTGGA GATGTCACCT CCTGCTCAGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTAAAGCG GCTCTTTAAG 
ATCCAGAACC TCAATGCCAG CACCATCCGC ACCGTGATGG TGGCTGACTG CAGCCGCTTT 
GATAGCCCGG ACCTCCTGCT GGATGCTGGT GACCAGGCTG GGCTCCCCTG CCGAGTCTTT 
GACCTAGGTG GGGACACTGA AGAAGAGGCC ACTGACCCAG GTTTGCACAC CTCTGGTTCT 
GGCCATGTCA AGGAAGGTTT ACGGCGTGTG TTTGATAGCG TCCTGGATGG ACATGGACAG 
CTGTCAGATT GTGCACTGGA GACCAAGGTG GCTGAGCTGC TGGCCCAGGG CCACACCAAG 
CCCCCAGAGT GTCCTGACGC TGACAGCAGG AACAAGTACC TCATCTTCAC CACTGGCTGC 
CTCACGTACT CACCTCATCA GATCGGCATC AAGCAGATCC TGCCGCACCA GATGACAACT 
GCAGGGCCCG TGCTGGGCGA GGGCCGGGGC TCTGATGCCT TCTTTGATGC CCTGGACCAT 
GTCATTGATG TGCATGGGCA CATCATTGGC ATGGGCCTGT CTCCCGATAA CAGGTACCTG 
TATGTGAATA GCCGTGCCTG GCCCCCTGGC TCAGTGGTCG CCGACCCCAT GCAGCCACCA 
CCCATTGCAG AGGAGATTGA CTTGCTGGTG TTTGATCTGA AGACCATGCG GGAGGTGAAG 
CGAGCTCTGC GAGCACACCG TGCCTACACA CCCAATGATG AGTGCTTCTT CATCTTTCTG 
GATGTCAGCA GGGATTTTGT GGCCAGTGGG GCTGAAGATC GGCATGGCTA TATCTGGGAC 
CGCCACTACA ACATCTGCCT AGCCAAGCTG CGGCATGAGG ATGTGGTCAA CTCAGTGGCC 
TTTAGCCCCC AGGAGCAGGA GCTCTTGTTG ACAGCCAGCG ATGATGCCAC TATCAAAGCC 
TGGCGCTCAC CACGCATTGT TCGTGTCCTG CAGGCTCCAC ACCCACGCCC ACGCCCCTTC 
TTCTCCTGGT TTGCCAGCCA TAGGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa25467
Clone ID Related Accession (Same CDS sequence) XM_006233628.3
Accession Version XM_006233628.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1476bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product F-box/WD repeat-containing protein 5 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233628.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGTGCCCT GTGTGGAGGT GCAGACACTG AAGGAGCACA CCGACCAGGT CCTGCACCTC 
AGCTTCTCCC ACTCGGGGTA CCAGTTTGCC TCCTGCTCCA AGGACTGCAC AGTGAAGATC 
TGGAACAATG ACCTGACCAT CTCTCTGCTG CACAGTGCAG ATATGAGGCC ATACAACTGG 
AGTTACACCC AGTTCTCCCA GTTCAACCAG GATGACTCAC TGTTGCTGGC CTCGGGGGTG 
TTCCTAGGGC CACATAACTC CTCCTCAGGC GAGATAGCTG TCATCAGCTT AGACTCCTTC 
GCCCTGCTGT CGCGTGTGCG AAACAAGCCC TATGATGTGT TTGGCTGCTG GCTCACAGAA 
ACCAGCCTCA TCTCGGGGAA CCTGCACCGC ATTGGAGATG TCACCTCCTG CTCAGTGCTG 
TGGCTCAACA ATGCCTTCCA GGATGTGGAG TCAGAGAACG TCAACGTGGT AAAGCGGCTC 
TTTAAGATCC AGAACCTCAA TGCCAGCACC ATCCGCACCG TGATGGTGGC TGACTGCAGC 
CGCTTTGATA GCCCGGACCT CCTGCTGGAT GCTGGTGACC AGGCTGGGCT CCCCTGCCGA 
GTCTTTGACC TAGGTGGGGA CACTGAAGAA GAGGCCACTG ACCCAGGTTT GCACACCTCT 
GGTTCTGGCC ATGTCAAGGA AGGTTTACGG CGTGTGTTTG ATAGCGTCCT GGATGGACAT 
GGACAGCTGT CAGATTGTGC ACTGGAGACC AAGGTGGCTG AGCTGCTGGC CCAGGGCCAC 
ACCAAGCCCC CAGAGTGTCC TGACGCTGAC AGCAGGAACA AGTACCTCAT CTTCACCACT 
GGCTGCCTCA CGTACTCACC TCATCAGATC GGCATCAAGC AGATCCTGCC GCACCAGATG 
ACAACTGCAG GGCCCGTGCT GGGCGAGGGC CGGGGCTCTG ATGCCTTCTT TGATGCCCTG 
GACCATGTCA TTGATGTGCA TGGGCACATC ATTGGCATGG GCCTGTCTCC CGATAACAGG 
TACCTGTATG TGAATAGCCG TGCCTGGCCC CCTGGCTCAG TGGTCGCCGA CCCCATGCAG 
CCACCACCCA TTGCAGAGGA GATTGACTTG CTGGTGTTTG ATCTGAAGAC CATGCGGGAG 
GTGAAGCGAG CTCTGCGAGC ACACCGTGCC TACACACCCA ATGATGAGTG CTTCTTCATC 
TTTCTGGATG TCAGCAGGGA TTTTGTGGCC AGTGGGGCTG AAGATCGGCA TGGCTATATC 
TGGGACCGCC ACTACAACAT CTGCCTAGCC AAGCTGCGGC ATGAGGATGT GGTCAACTCA 
GTGGCCTTTA GCCCCCAGGA GCAGGAGCTC TTGTTGACAG CCAGCGATGA TGCCACTATC 
AAAGCCTGGC GCTCACCACG CATTGTTCGT GTCCTGCAGG CTCCACACCC ACGCCCACGC 
CCCTTCTTCT CCTGGTTTGC CAGCCATAGG CGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006233690.1
CDS131..1606
Translation

Target ORF information:

RefSeq Version XM_006233628.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006233628.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGTGCCCT GTGTGGAGGT GCAGACACTG AAGGAGCACA CCGACCAGGT CCTGCACCTC 
AGCTTCTCCC ACTCGGGGTA CCAGTTTGCC TCCTGCTCCA AGGACTGCAC AGTGAAGATC 
TGGAACAATG ACCTGACCAT CTCTCTGCTG CACAGTGCAG ATATGAGGCC ATACAACTGG 
AGTTACACCC AGTTCTCCCA GTTCAACCAG GATGACTCAC TGTTGCTGGC CTCGGGGGTG 
TTCCTAGGGC CACATAACTC CTCCTCAGGC GAGATAGCTG TCATCAGCTT AGACTCCTTC 
GCCCTGCTGT CGCGTGTGCG AAACAAGCCC TATGATGTGT TTGGCTGCTG GCTCACAGAA 
ACCAGCCTCA TCTCGGGGAA CCTGCACCGC ATTGGAGATG TCACCTCCTG CTCAGTGCTG 
TGGCTCAACA ATGCCTTCCA GGATGTGGAG TCAGAGAACG TCAACGTGGT AAAGCGGCTC 
TTTAAGATCC AGAACCTCAA TGCCAGCACC ATCCGCACCG TGATGGTGGC TGACTGCAGC 
CGCTTTGATA GCCCGGACCT CCTGCTGGAT GCTGGTGACC AGGCTGGGCT CCCCTGCCGA 
GTCTTTGACC TAGGTGGGGA CACTGAAGAA GAGGCCACTG ACCCAGGTTT GCACACCTCT 
GGTTCTGGCC ATGTCAAGGA AGGTTTACGG CGTGTGTTTG ATAGCGTCCT GGATGGACAT 
GGACAGCTGT CAGATTGTGC ACTGGAGACC AAGGTGGCTG AGCTGCTGGC CCAGGGCCAC 
ACCAAGCCCC CAGAGTGTCC TGACGCTGAC AGCAGGAACA AGTACCTCAT CTTCACCACT 
GGCTGCCTCA CGTACTCACC TCATCAGATC GGCATCAAGC AGATCCTGCC GCACCAGATG 
ACAACTGCAG GGCCCGTGCT GGGCGAGGGC CGGGGCTCTG ATGCCTTCTT TGATGCCCTG 
GACCATGTCA TTGATGTGCA TGGGCACATC ATTGGCATGG GCCTGTCTCC CGATAACAGG 
TACCTGTATG TGAATAGCCG TGCCTGGCCC CCTGGCTCAG TGGTCGCCGA CCCCATGCAG 
CCACCACCCA TTGCAGAGGA GATTGACTTG CTGGTGTTTG ATCTGAAGAC CATGCGGGAG 
GTGAAGCGAG CTCTGCGAGC ACACCGTGCC TACACACCCA ATGATGAGTG CTTCTTCATC 
TTTCTGGATG TCAGCAGGGA TTTTGTGGCC AGTGGGGCTG AAGATCGGCA TGGCTATATC 
TGGGACCGCC ACTACAACAT CTGCCTAGCC AAGCTGCGGC ATGAGGATGT GGTCAACTCA 
GTGGCCTTTA GCCCCCAGGA GCAGGAGCTC TTGTTGACAG CCAGCGATGA TGCCACTATC 
AAAGCCTGGC GCTCACCACG CATTGTTCGT GTCCTGCAGG CTCCACACCC ACGCCCACGC 
CCCTTCTTCT CCTGGTTTGC CAGCCATAGG CGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa25466
Clone ID Related Accession (Same CDS sequence) XM_006233623.2
Accession Version XM_006233623.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1875bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product F-box/WD repeat-containing protein 5 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006233623.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGCTCAGTG CAATGGAATT CTCGGCTGGG CAGTTGGTGG GGCTGGCTAG GACTGCCATG 
TCTGGAACCC CAGACCATCA GTCTCTCCCT GGGGTTGGGG GTGAGGAGGC CTGGGTTGAG 
AGCAGCCACT GGTGGGTTTC AGGACCGTCT GGGCAGAATG TCACGATGGA TGAGGGGGGC 
ATGCCCCTGC TCCCCGACAG CCTGGTCTAC CAGATCTTCC TGAGCTTGGG CCCTGCAGAT 
GTGCTGGCTG CTGGGCTGGT GTGCCGCCAG TGGCAGGCTG TCTCCCGGGA CGAGTTCCTA 
TGGAGGGAGC AGTTCTACCG CTACTACCAG GTGGCTCGCG ATGTGCCCCG CCACCCAGCG 
GCCACATCCT GGTATGAGGA GTTCCGGCGG CTCTATGACA TGGTGCCCTG TGTGGAGGTG 
CAGACACTGA AGGAGCACAC CGACCAGGTC CTGCACCTCA GCTTCTCCCA CTCGGGGTAC 
CAGTTTGCCT CCTGCTCCAA GGACTGCACA GTGAAGATCT GGAACAATGA CCTGACCATC 
TCTCTGCTGC ACAGTGCAGA TATGAGGCCA TACAACTGGA GTTACACCCA GTTCTCCCAG 
TTCAACCAGG ATGACTCACT GTTGCTGGCC TCGGGGGTGT TCCTAGGGCC ACATAACTCC 
TCCTCAGGCG AGATAGCTGT CATCAGCTTA GACTCCTTCG CCCTGCTGTC GCGTGTGCGA 
AACAAGCCCT ATGATGTGTT TGGCTGCTGG CTCACAGAAA CCAGCCTCAT CTCGGGGAAC 
CTGCACCGCA TTGGAGATGT CACCTCCTGC TCAGTGCTGT GGCTCAACAA TGCCTTCCAG 
GATGTGGAGT CAGAGAACGT CAACGTGGTA AAGCGGCTCT TTAAGATCCA GAACCTCAAT 
GCCAGCACCA TCCGCACCGT GATGGTGGCT GACTGCAGCC GCTTTGATAG CCCGGACCTC 
CTGCTGGATG CTGGTGACCA GGCTGGGCTC CCCTGCCGAG TCTTTGACCT AGGTGGGGAC 
ACTGAAGAAG AGGCCACTGA CCCAGGTTTG CACACCTCTG GTTCTGGCCA TGTCAAGGAA 
GGTTTACGGC GTGTGTTTGA TAGCGTCCTG GATGGACATG GACAGCTGTC AGATTGTGCA 
CTGGAGACCA AGGTGGCTGA GCTGCTGGCC CAGGGCCACA CCAAGCCCCC AGAGTGTCCT 
GACGCTGACA GCAGGAACAA GTACCTCATC TTCACCACTG GCTGCCTCAC GTACTCACCT 
CATCAGATCG GCATCAAGCA GATCCTGCCG CACCAGATGA CAACTGCAGG GCCCGTGCTG 
GGCGAGGGCC GGGGCTCTGA TGCCTTCTTT GATGCCCTGG ACCATGTCAT TGATGTGCAT 
GGGCACATCA TTGGCATGGG CCTGTCTCCC GATAACAGGT ACCTGTATGT GAATAGCCGT 
GCCTGGCCCC CTGGCTCAGT GGTCGCCGAC CCCATGCAGC CACCACCCAT TGCAGAGGAG 
ATTGACTTGC TGGTGTTTGA TCTGAAGACC ATGCGGGAGG TGAAGCGAGC TCTGCGAGCA 
CACCGTGCCT ACACACCCAA TGATGAGTGC TTCTTCATCT TTCTGGATGT CAGCAGGGAT 
TTTGTGGCCA GTGGGGCTGA AGATCGGCAT GGCTATATCT GGGACCGCCA CTACAACATC 
TGCCTAGCCA AGCTGCGGCA TGAGGATGTG GTCAACTCAG TGGCCTTTAG CCCCCAGGAG 
CAGGAGCTCT TGTTGACAGC CAGCGATGAT GCCACTATCA AAGCCTGGCG CTCACCACGC 
ATTGTTCGTG TCCTGCAGGC TCCACACCCA CGCCCACGCC CCTTCTTCTC CTGGTTTGCC 
AGCCATAGGC GCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006233685.1
CDS323..2197
Translation

Target ORF information:

RefSeq Version XM_006233623.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus F-box and WD repeat domain containing 5 (Fbxw5), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006233623.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGCTCAGTG CAATGGAATT CTCGGCTGGG CAGTTGGTGG GGCTGGCTAG GACTGCCATG 
TCTGGAACCC CAGACCATCA GTCTCTCCCT GGGGTTGGGG GTGAGGAGGC CTGGGTTGAG 
AGCAGCCACT GGTGGGTTTC AGGACCGTCT GGGCAGAATG TCACGATGGA TGAGGGGGGC 
ATGCCCCTGC TCCCCGACAG CCTGGTCTAC CAGATCTTCC TGAGCTTGGG CCCTGCAGAT 
GTGCTGGCTG CTGGGCTGGT GTGCCGCCAG TGGCAGGCTG TCTCCCGGGA CGAGTTCCTA 
TGGAGGGAGC AGTTCTACCG CTACTACCAG GTGGCTCGCG ATGTGCCCCG CCACCCAGCG 
GCCACATCCT GGTATGAGGA GTTCCGGCGG CTCTATGACA TGGTGCCCTG TGTGGAGGTG 
CAGACACTGA AGGAGCACAC CGACCAGGTC CTGCACCTCA GCTTCTCCCA CTCGGGGTAC 
CAGTTTGCCT CCTGCTCCAA GGACTGCACA GTGAAGATCT GGAACAATGA CCTGACCATC 
TCTCTGCTGC ACAGTGCAGA TATGAGGCCA TACAACTGGA GTTACACCCA GTTCTCCCAG 
TTCAACCAGG ATGACTCACT GTTGCTGGCC TCGGGGGTGT TCCTAGGGCC ACATAACTCC 
TCCTCAGGCG AGATAGCTGT CATCAGCTTA GACTCCTTCG CCCTGCTGTC GCGTGTGCGA 
AACAAGCCCT ATGATGTGTT TGGCTGCTGG CTCACAGAAA CCAGCCTCAT CTCGGGGAAC 
CTGCACCGCA TTGGAGATGT CACCTCCTGC TCAGTGCTGT GGCTCAACAA TGCCTTCCAG 
GATGTGGAGT CAGAGAACGT CAACGTGGTA AAGCGGCTCT TTAAGATCCA GAACCTCAAT 
GCCAGCACCA TCCGCACCGT GATGGTGGCT GACTGCAGCC GCTTTGATAG CCCGGACCTC 
CTGCTGGATG CTGGTGACCA GGCTGGGCTC CCCTGCCGAG TCTTTGACCT AGGTGGGGAC 
ACTGAAGAAG AGGCCACTGA CCCAGGTTTG CACACCTCTG GTTCTGGCCA TGTCAAGGAA 
GGTTTACGGC GTGTGTTTGA TAGCGTCCTG GATGGACATG GACAGCTGTC AGATTGTGCA 
CTGGAGACCA AGGTGGCTGA GCTGCTGGCC CAGGGCCACA CCAAGCCCCC AGAGTGTCCT 
GACGCTGACA GCAGGAACAA GTACCTCATC TTCACCACTG GCTGCCTCAC GTACTCACCT 
CATCAGATCG GCATCAAGCA GATCCTGCCG CACCAGATGA CAACTGCAGG GCCCGTGCTG 
GGCGAGGGCC GGGGCTCTGA TGCCTTCTTT GATGCCCTGG ACCATGTCAT TGATGTGCAT 
GGGCACATCA TTGGCATGGG CCTGTCTCCC GATAACAGGT ACCTGTATGT GAATAGCCGT 
GCCTGGCCCC CTGGCTCAGT GGTCGCCGAC CCCATGCAGC CACCACCCAT TGCAGAGGAG 
ATTGACTTGC TGGTGTTTGA TCTGAAGACC ATGCGGGAGG TGAAGCGAGC TCTGCGAGCA 
CACCGTGCCT ACACACCCAA TGATGAGTGC TTCTTCATCT TTCTGGATGT CAGCAGGGAT 
TTTGTGGCCA GTGGGGCTGA AGATCGGCAT GGCTATATCT GGGACCGCCA CTACAACATC 
TGCCTAGCCA AGCTGCGGCA TGAGGATGTG GTCAACTCAG TGGCCTTTAG CCCCCAGGAG 
CAGGAGCTCT TGTTGACAGC CAGCGATGAT GCCACTATCA AAGCCTGGCG CTCACCACGC 
ATTGTTCGTG TCCTGCAGGC TCCACACCCA CGCCCACGCC CCTTCTTCTC CTGGTTTGCC 
AGCCATAGGC GCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Tnfaip8?l1/Oxi-? binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.
Journal of neurochemistry129(3)527-38(2014 May)
Ha JY,Kim JS,Kang YH,Bok E,Kim YS,Son JH


book

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression.
Nature cell biology15(2)179-88(2013 Feb)
Werner A,Disanza A,Reifenberger N,Habeck G,Becker J,Calabrese M,Urlaub H,Lorenz H,Schulman B,Scita G,Melchior F


book

The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication.
Nature cell biology13(8)1004-9(2011 Jul)
Puklowski A,Homsi Y,Keller D,May M,Chauhan S,Kossatz U,Gr?nwald V,Kubicka S,Pich A,Manns MP,Hoffmann I,G?nczy P,Malek NP


book

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
The international journal of biochemistry & cell biology41(5)1205-15(2009 May)
Ebstein F,Lange N,Urban S,Seifert U,Kr?ger E,Kloetzel PM


book

WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
Genes & development22(7)866-71(2008 Apr)
Hu J,Zacharek S,He YJ,Lee H,Shumway S,Duronio RJ,Xiong Y