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Cml2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Cml2
Entrez Gene ID 500237
Full Name camello-like 2
Synonyms RGD1561619
General protein information
Preferred Names

camello-like 2

Names

probable N-acetyltransferase CML2
camello-like protein 2
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

4

4q34

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001173449.1 NP_001166920.1 N-acetyltransferase family 8 member 2
XM_006236785.3 XP_006236847.1 probable N-acetyltransferase CML2 isoform X1

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) LOC100910829 XP_006236861.1
Rattus norvegicus (Norway rat) LOC102556148 XP_006236864.1
Rattus norvegicus (Norway rat) Cml2 NP_001166920.1
Mus musculus (house mouse) 1700019G17Rik NP_083607.3
Rattus norvegicus (Norway rat) LOC102549803 XP_006236880.1

Gene Ontology


Bibliography

Related articles in PubMed

Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces ?-secretase (BACE1) levels and A? generation.
Ding Y, Ko MH, Pehar M, Kotch F, Peters NR, Luo Y, Salamat SM, Puglielli L
The Journal of biological chemistry287(11)8424-33(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces beta-secretase (BACE1) levels and Abeta generation.
Title: Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces ?-secretase (BACE1) levels and A? generation.

The following Cml2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cml2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa27421 NM_001173449.1
Latest version!		 Rattus norvegicus camello-like 2 (Cml2), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
ORa27421 XM_006236785.3
Latest version!		 Rattus norvegicus camello-like 2 (Cml2), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa27421
Clone ID Related Accession (Same CDS sequence) NM_001173449.1 , XM_006236785.3
Accession Version NM_001173449.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 681bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-21
Organism Rattus norvegicus(Norway rat)
Product N-acetyltransferase family 8 member 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07061345.1. On or before May 13, 2010 this sequence version replaced XM_001074225.1, XM_575587.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTCCTT ATCACATCAG ACAGTTCCAG GACAGGGACC ACAGAAGAGT CCTGGACTTG 
TTCTCCAGAG GCATGGAGGA GCATGTCCCT GCTGCCTTCT ACCATGTGCT GACACTGCCT 
CATTCTCTCC TGCTCTTTCC TGGGGTGCCC GTGACCATAA TCCTAGTGTC TGGTTCTTGG 
CTCCTGGCCA CAGTGTACAG TTTCCTCTTT CTCCTTTGCC TGCGGCTCAT TTTCTGGGTT 
TCATGCAGAA ATTATGTGGC TAAATGTTTG CAGGCCGACT TGGCTGACAT CACCAAGTCT 
TACCTGAATG CACATGGCTC CTTCTGGGTG GCTGAGTCTG GGGGGCAGGT GGTGGGCATA 
GTGGCTGCTC TGCCAGTCAA GGAGCCTCCA TCAGGGAGGA AGCAGTTGCA GCTCTTCCGC 
CTGTCTGTGT CCTCACAGCA TCGAGGACAG GGGATAGCGA AAGCACTGGT CAGAATTGTG 
CTCCAGTTTG CACGGGACCA GGGCTACACG GATGTTGTCC TTGTGACTGG CAATATGCAG 
TATAGCGCTA TGTCTCTGTA CCAGGGCATG GGCTTCCAGA AGACAGGCCA TTACTTCGTC 
AGCATAGCCA AGAGGTTAAT TGGTCTTTCT ATCTTTCATT TCACCTACTC TCTCCCTTCT 
GTTTGGGAAC CAAGAATGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001166920.1
CDS1..681
Translation

Target ORF information:

RefSeq Version NM_001173449.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus camello-like 2 (Cml2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001173449.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTCCTT ATCACATCAG ACAGTTCCAG GACAGGGACC ACAGAAGAGT CCTGGACTTG 
TTCTCCAGAG GCATGGAGGA GCATGTCCCT GCTGCCTTCT ACCATGTGCT GACACTGCCT 
CATTCTCTCC TGCTCTTTCC TGGGGTGCCC GTGACCATAA TCCTAGTGTC TGGTTCTTGG 
CTCCTGGCCA CAGTGTACAG TTTCCTCTTT CTCCTTTGCC TGCGGCTCAT TTTCTGGGTT 
TCATGCAGAA ATTATGTGGC TAAATGTTTG CAGGCCGACT TGGCTGACAT CACCAAGTCT 
TACCTGAATG CACATGGCTC CTTCTGGGTG GCTGAGTCTG GGGGGCAGGT GGTGGGCATA 
GTGGCTGCTC TGCCAGTCAA GGAGCCTCCA TCAGGGAGGA AGCAGTTGCA GCTCTTCCGC 
CTGTCTGTGT CCTCACAGCA TCGAGGACAG GGGATAGCGA AAGCACTGGT CAGAATTGTG 
CTCCAGTTTG CACGGGACCA GGGCTACACG GATGTTGTCC TTGTGACTGG CAATATGCAG 
TATAGCGCTA TGTCTCTGTA CCAGGGCATG GGCTTCCAGA AGACAGGCCA TTACTTCGTC 
AGCATAGCCA AGAGGTTAAT TGGTCTTTCT ATCTTTCATT TCACCTACTC TCTCCCTTCT 
GTTTGGGAAC CAAGAATGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa27421
Clone ID Related Accession (Same CDS sequence) NM_001173449.1 , XM_006236785.3
Accession Version XM_006236785.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 681bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product probable N-acetyltransferase CML2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236785.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTCCTT ATCACATCAG ACAGTTCCAG GACAGGGACC ACAGAAGAGT CCTGGACTTG 
TTCTCCAGAG GCATGGAGGA GCATGTCCCT GCTGCCTTCT ACCATGTGCT GACACTGCCT 
CATTCTCTCC TGCTCTTTCC TGGGGTGCCC GTGACCATAA TCCTAGTGTC TGGTTCTTGG 
CTCCTGGCCA CAGTGTACAG TTTCCTCTTT CTCCTTTGCC TGCGGCTCAT TTTCTGGGTT 
TCATGCAGAA ATTATGTGGC TAAATGTTTG CAGGCCGACT TGGCTGACAT CACCAAGTCT 
TACCTGAATG CACATGGCTC CTTCTGGGTG GCTGAGTCTG GGGGGCAGGT GGTGGGCATA 
GTGGCTGCTC TGCCAGTCAA GGAGCCTCCA TCAGGGAGGA AGCAGTTGCA GCTCTTCCGC 
CTGTCTGTGT CCTCACAGCA TCGAGGACAG GGGATAGCGA AAGCACTGGT CAGAATTGTG 
CTCCAGTTTG CACGGGACCA GGGCTACACG GATGTTGTCC TTGTGACTGG CAATATGCAG 
TATAGCGCTA TGTCTCTGTA CCAGGGCATG GGCTTCCAGA AGACAGGCCA TTACTTCGTC 
AGCATAGCCA AGAGGTTAAT TGGTCTTTCT ATCTTTCATT TCACCTACTC TCTCCCTTCT 
GTTTGGGAAC CAAGAATGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006236847.1
CDS353..1033
Translation

Target ORF information:

RefSeq Version XM_006236785.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus camello-like 2 (Cml2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006236785.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTCCTT ATCACATCAG ACAGTTCCAG GACAGGGACC ACAGAAGAGT CCTGGACTTG 
TTCTCCAGAG GCATGGAGGA GCATGTCCCT GCTGCCTTCT ACCATGTGCT GACACTGCCT 
CATTCTCTCC TGCTCTTTCC TGGGGTGCCC GTGACCATAA TCCTAGTGTC TGGTTCTTGG 
CTCCTGGCCA CAGTGTACAG TTTCCTCTTT CTCCTTTGCC TGCGGCTCAT TTTCTGGGTT 
TCATGCAGAA ATTATGTGGC TAAATGTTTG CAGGCCGACT TGGCTGACAT CACCAAGTCT 
TACCTGAATG CACATGGCTC CTTCTGGGTG GCTGAGTCTG GGGGGCAGGT GGTGGGCATA 
GTGGCTGCTC TGCCAGTCAA GGAGCCTCCA TCAGGGAGGA AGCAGTTGCA GCTCTTCCGC 
CTGTCTGTGT CCTCACAGCA TCGAGGACAG GGGATAGCGA AAGCACTGGT CAGAATTGTG 
CTCCAGTTTG CACGGGACCA GGGCTACACG GATGTTGTCC TTGTGACTGG CAATATGCAG 
TATAGCGCTA TGTCTCTGTA CCAGGGCATG GGCTTCCAGA AGACAGGCCA TTACTTCGTC 
AGCATAGCCA AGAGGTTAAT TGGTCTTTCT ATCTTTCATT TCACCTACTC TCTCCCTTCT 
GTTTGGGAAC CAAGAATGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces ?-secretase (BACE1) levels and A? generation.
The Journal of biological chemistry287(11)8424-33(2012 Mar)
Ding Y,Ko MH,Pehar M,Kotch F,Peters NR,Luo Y,Salamat SM,Puglielli L