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Pdcd4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Pdcd4
Entrez Gene ID 64031
Full Name programmed cell death 4
Synonyms Dug
General protein information
Preferred Names

programmed cell death 4

Names

programmed cell death protein 4
death up-regulated gene protein
death-upregulated
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

1

1q55
Summary acts as an inhibitor of apoptosis; has similarity to eukaryotic translation initiation factor (eIF)4G [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_017589648.1 XP_017445137.1 programmed cell death protein 4 isoform X1
XM_006231614.3 XP_006231676.1 programmed cell death protein 4 isoform X1
XM_006231615.3 XP_006231677.1 programmed cell death protein 4 isoform X1
NM_022265.2 NP_071601.2 programmed cell death protein 4
XM_006231616.3 XP_006231678.1 programmed cell death protein 4 isoform X1
XM_006231613.3 XP_006231675.1 programmed cell death protein 4 isoform X1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) PDCD4 XP_001143772.1
PDCD4 XP_001086788.1
Canis lupus familiaris (dog) PDCD4 XP_005637778.1
Bos taurus (cattle) PDCD4 NP_001077116.1
Mus musculus (house mouse) Pdcd4 NP_001161964.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP000378 XP_310731.4
Rattus norvegicus (Norway rat) Pdcd4 NP_071601.2
Gallus gallus (chicken) PDCD4 NP_989635.1
Oryza sativa (rice) Os08g0120500 NP_001060879.1
Xenopus tropicalis (tropical clawed frog) pdcd4 NP_998871.1
Drosophila melanogaster (fruit fly) Pdcd4 NP_001096977.1
Arabidopsis thaliana (thale cress) AT4G24800 NP_001031708.1
Homo sapiens (human) PDCD4 NP_055271.2
Danio rerio (zebrafish) pdcd4b NP_945329.1
Arabidopsis thaliana (thale cress) AT5G63190 NP_568968.1

Gene Ontology


Bibliography

Related articles in PubMed

MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Wang L, Ye N, Lian X, Peng F, Zhang H, Gong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie981-8(2017 Dec)

Depletion of the mRNA translation initiation inhibitor, programmed cell death protein 4 (PDCD4), impairs L6 myotube formation.
Maeda N, Abdullahi A, Beatty B, Dhanani Z, Adegoke OAJ
Physiological reports5(17)(2017 Sep)

Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis.
Fu X, He Y, Wang X, Peng D, Chen X, Li X, Wang Q
Stem cell research & therapy8(1)187(2017 Aug)

The role of tumour suppressor PDCD4 in beta cell death in hypoxia.
Kumar S, Marriott CE, Alhasawi NF, Bone AJ, Macfarlane WM
PloS one12(7)e0181235(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

-induced expression of PDCD4 is associated with increased beta cell death.
Title: The role of tumour suppressor PDCD4 in beta cell death in hypoxia.

cardiac progenitor cell-derived exosomal miR-21 had an inhibiting role in the apoptosis pathway through downregulating PDCD4.
Title: Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4.

Findings revealed the role of miR-499-5p in protecting the cardiomyocytes against apoptosis induced by acute myocardial infarction (AMI) via its direct target PDCD4, which providing evidence for the miR-499-5p/PDCD4 pathway as a potential therapeutic target for patients with AMI.
Title: MiR-499-5p protects cardiomyocytes against ischaemic injury via anti-apoptosis by targeting PDCD4.

The apoptosis process enhanced by overexpression of SOX6 or PDCD4, was rescued by the cardiac-abundant miR-499 in rat cardiomyocytes.
Title: SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition.

Ischemic postconditioning (IPC)-regulated miR-499 plays an important role in IPC-mediated cardiac protection against myocardial ischemia/reperfusion injury by targeting PDCD4.
Title: Ischemic Postconditioning-Regulated miR-499 Protects the Rat Heart Against Ischemia/Reperfusion Injury by Inhibiting Apoptosis through PDCD4.

The following Pdcd4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pdcd4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa05578 NM_022265.2
Latest version!		 Rattus norvegicus programmed cell death 4 (Pdcd4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
ORa05578 XM_006231614.3
Latest version!		 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
ORa05578 XM_006231615.3
Latest version!		 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
ORa05578 XM_017589648.1
Latest version!		 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
ORa05578 XM_006231616.3
Latest version!		 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
ORa05578 XM_006231613.3
Latest version!		 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
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All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa05578
Clone ID Related Accession (Same CDS sequence) XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version NM_022265.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-26
Organism Rattus norvegicus(Norway rat)
Product programmed cell death protein 4
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF239739.2. On Jul 22, 2002 this sequence version replaced NM_022265.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF239739.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_071601.2
CDS1..1410
Translation

Target ORF information:

RefSeq Version NM_022265.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus programmed cell death 4 (Pdcd4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_022265.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa05578
Clone ID Related Accession (Same CDS sequence) XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version XM_017589648.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product programmed cell death protein 4 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017445137.1
CDS88..1497
Translation

Target ORF information:

RefSeq Version XM_017589648.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017589648.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa05578
Clone ID Related Accession (Same CDS sequence) XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version XM_006231614.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product programmed cell death protein 4 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231614.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006231676.1
CDS333..1742
Translation

Target ORF information:

RefSeq Version XM_006231614.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006231614.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa05578
Clone ID Related Accession (Same CDS sequence) XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version XM_006231615.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product programmed cell death protein 4 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231615.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006231677.1
CDS173..1582
Translation

Target ORF information:

RefSeq Version XM_006231615.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006231615.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa05578
Clone ID Related Accession (Same CDS sequence) XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version XM_006231616.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product programmed cell death protein 4 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231616.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006231678.1
CDS156..1565
Translation

Target ORF information:

RefSeq Version XM_006231616.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006231616.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa05578
Clone ID Related Accession (Same CDS sequence) XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version XM_006231613.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product programmed cell death protein 4 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231613.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006231675.1
CDS282..1691
Translation

Target ORF information:

RefSeq Version XM_006231613.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006231613.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie981-8(2017 Dec)
Wang L,Ye N,Lian X,Peng F,Zhang H,Gong H


book

Depletion of the mRNA translation initiation inhibitor, programmed cell death protein 4 (PDCD4), impairs L6 myotube formation.
Physiological reports5(17)(2017 Sep)
Maeda N,Abdullahi A,Beatty B,Dhanani Z,Adegoke OAJ


book

Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis.
Stem cell research & therapy8(1)187(2017 Aug)
Fu X,He Y,Wang X,Peng D,Chen X,Li X,Wang Q


book

The role of tumour suppressor PDCD4 in beta cell death in hypoxia.
PloS one12(7)e0181235(2017)
Kumar S,Marriott CE,Alhasawi NF,Bone AJ,Macfarlane WM