| Gene Symbol | RGS16 |
| Entrez Gene ID | 397544 |
| Full Name | regulator of G protein signaling 16 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
IVD Raw Materials
ORF » Species Summary » Sus scrofa » RGS16 cDNA ORF clone
| Gene Symbol | RGS16 |
| Entrez Gene ID | 397544 |
| Full Name | regulator of G protein signaling 16 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
| mRNA | Protein | Name |
|---|---|---|
| XM_021063763.1 | XP_020919422.1 | regulator of G-protein signaling 16 |
| NM_001113017.1 | NP_001106488.1 | regulator of G-protein signaling 16 |
The ORF3 protein of porcine circovirus type 2 promotes secretion of IL-6 and IL-8 in porcine epithelial cells by facilitating proteasomal degradation of regulator of G protein signalling 16 through physical interaction.
Choi CY, Rho SB, Kim HS, Han J, Bae J, Lee SJ, Jung WW, Chun T
The Journal of general virology96(Pt 5)1098-108(2015 May)
Regulator of G protein signalling 16 is a target for a porcine circovirus type 2 protein.
Timmusk S, Merlot E, L?vgren T, J?rvek?lg L, Berg M, Fossum C
The Journal of general virology90(Pt 10)2425-36(2009 Oct)
PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D, Hamasima N, Awata T
Nucleic acids research35(Database issue)D650-3(2007 Jan)
PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Uenishi H, Eguchi T, Suzuki K, Sawazaki T, Toki D, Shinkai H, Okumura N, Hamasima N, Awata T
Nucleic acids research32(Database issue)D484-8(2004 Jan)
Regulators of G-protein signaling (RGS) 1 and 16 are induced in response to bacterial lipopolysaccharide and stimulate c-fos promoter expression.
Panetta R, Guo Y, Magder S, Greenwood MT
Biochemical and biophysical research communications259(3)550-6(1999 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Facilitated degradation of the RGS16 by porcine circovirus type 2 ORF3 further enhances NFkappaB translocation into the nucleus through the ERK1/2 signalling pathway and increased IL-6 and IL-8 mRNA transcripts.
Title: The ORF3 protein of porcine circovirus type 2 promotes secretion of IL-6 and IL-8 in porcine epithelial cells by facilitating proteasomal degradation of regulator of G protein signalling 16 through physical interaction.
The role of RGS16 in porcine circovirus infections via its binding with a nonstructural protein encoded by open reading frame 3 is reported.
Title: Regulator of G protein signalling 16 is a target for a porcine circovirus type 2 protein.
The following RGS16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RGS16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe29233 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001113017.1 | |
| Accession Version | NM_001113017.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-19 | |
| Organism | Sus scrofa(pig) | |
| Product | regulator of G-protein signaling 16 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EU271873.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EU271873.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02584787, SAMN02584789 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTGCCGGA CCCTGGCTGC CTTCCCCACC ACCTGCCTGG AGAGAGCCAA AGAGTTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001106488.1 |
| CDS | 14..622 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001113017.1 |
1 | ATGTGCCGGA CCCTGGCTGC CTTCCCCACC ACCTGCCTGG AGAGAGCCAA AGAGTTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe40049 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021063763.1 | |
| Accession Version | XM_021063763.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | regulator of G-protein signaling 16 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010451.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGCCGGA CCCTGGCTGC CTTCCCCACC ACCTGCCTGG AGAGAGCCAA AGAGTTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020919422.1 |
| CDS | 370..972 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021063763.1 |
1 | ATGTGCCGGA CCCTGGCTGC CTTCCCCACC ACCTGCCTGG AGAGAGCCAA AGAGTTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The ORF3 protein of porcine circovirus type 2 promotes secretion of IL-6 and IL-8 in porcine epithelial cells by facilitating proteasomal degradation of regulator of G protein signalling 16 through physical interaction. |
Regulator of G protein signalling 16 is a target for a porcine circovirus type 2 protein. |
PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. |
PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. |
Regulators of G-protein signaling (RGS) 1 and 16 are induced in response to bacterial lipopolysaccharide and stimulate c-fos promoter expression. |