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Next generation sequencing

Next-generation sequencing (NGS), also known as high-throughput sequencing, is a powerful and rapidly evolving technology that allows for the rapid and efficient sequencing of DNA and RNA samples. It has revolutionized the field of genomics, making it possible to sequence entire genomes, transcriptomes, and epigenomes much more quickly and cost-effectively than previous technologies

. NGS technology uses highly parallel sequencing platforms to generate massive sequence data in a single experiment. This is achieved through massively parallel sequencing methods, which allow for many thousands or even millions of sequencing reactions to be run in parallel on a single chip or flow cell.

NGS has many applications, including whole genome sequencing, targeted sequencing of specific regions of interest, transcriptome sequencing to study gene expression, metagenomic sequencing to explore microbial communities, and epigenomic sequencing to learn DNA methylation and histone modifications.

The data generated by NGS experiments is typically analyzed using bioinformatics tools and software to assemble and align the sequence reads, identify genetic variants, quantify gene expression levels, and perform other types of analysis. NGS has enabled many discoveries in genetics and has the potential to transform personalized medicine by allowing for the identification of genetic variations associated with disease susceptibility and drug response.

Related Biology Tools

  • GenSmart™ Codon Optimization

    GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.

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  • DNA Construct Design Tool

    GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.

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  • Codon Frequency Tables

    This online tool shows commonly used genetic codon frequency table in expression host organisms including Escherichia coli and other common host organisms.

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Service and Products

Gene Synthesis

Offer gene synthesis of 100% sequence guarantee, free codon optimization, DNA synthesis in as fast as 4 days.

ORF cDNA Clones and Custom Clones

Largest commercial ORF clones database, 70,000 next-day shipping ORF clones.

Plasmid DNA Preparation

High quality plasmids supported by fully-automated platform, 100% full insert sequence accuracy guaranteed.

Express Cloning & Subcloning

$49 and 2 day turnaround, choose from over 150 IP FREE vectors.

Mutation and Library Services

Mutagenesis Portfolio offers several mutation and library services to meet various customers’ needs.

Oligo Synthesis

Bridge the gap between chemically synthesized oligos and bological applications.

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