Resources

List by Alphabet: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

transmethylation

Transmethylation is a biologically crucial organic chemical reaction in which a methyl group is transferred from one compound to another.

Transmethylation can also be regarded as a transfer of a methyl group from one compound to another; e.g., l-homocysteine is converted to l-methionine by the transfer to the latter of a methyl group.

The mechanism of transmethylation was then examined. A series of deuterium-labeled methylated compounds were synthesized by du Vigneaud's group, including arsenocholine, trimethylamine, dimethylglycine, and dimethylthetin. Of these, only betaine and dimethylthetin served as methyl donors. In 1949, Dubnoff found that choline could only act as a donor under aerobic conditions when it was oxidized to betaine.

A vital metabolite for most transmethylation reactions of the body is SAM. It is generated directly from methionine by a reaction catalyzed by MAT.

Related Biology Tools

  • GenSmart™ Codon Optimization

    GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.

    Learn More

  • DNA Construct Design Tool

    GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.

    Learn More

  • Codon Frequency Tables

    This online tool shows commonly used genetic codon frequency table in expression host organisms including Escherichia coli and other common host organisms.

    Learn More

Service and Products

Gene Synthesis

Offer gene synthesis of 100% sequence guarantee, free codon optimization, DNA synthesis in as fast as 4 days.

ORF cDNA Clones and Custom Clones

Largest commercial ORF clones database, 70,000 next-day shipping ORF clones.

Plasmid DNA Preparation

High quality plasmids supported by fully-automated platform, 100% full insert sequence accuracy guaranteed.

Express Cloning & Subcloning

$49 and 2 day turnaround, choose from over 150 IP FREE vectors.

Mutation and Library Services

Mutagenesis Portfolio offers several mutation and library services to meet various customers’ needs.

Oligo Synthesis

Bridge the gap between chemically synthesized oligos and bological applications.

If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]

If your term is adopted, we will send 1,000 EzCoupon points to your GenScript account.