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active immunity

Active immunity is a kind of immunity generated by an organism's production of antibodies and cytokines. It is defined as immunity to a pathogen that occurs following exposure to a given pathogen.

When the body is exposed to a novel disease agent, B cells, a type of white blood cell, create antibodies that assist in destroying or neutralizing the disease agent.

Active immunization is the induction of immunity after exposure to an antigen. Antibodies are created by the recipient and may be stored permanently.

Active immunity can result from developing antibodies in response to the presence of an antigen, as from vaccination or exposure to an infectious virus. According to a recent experiment, active immunity against rotavirus infection in mice is correlated with viral replication and titers of serum rotavirus IgA following vaccination. By comparison, active immunity is longer-lasting and more effective than passive immunity due to the immunologic memory produced by the patient's own immune system.

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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]

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