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anti-inflammatory cytokines

Cytokines such as IL-10, IL-4, and IL-12 that are involved in the reduction of inflammatory reactions.

Anti-inflammatory cytokines counterbalance the chronic activation of innate and adaptive immune cells in rheumatoid arthritis (RA). The anti-inflammatory cytokines are a series of immunoregulatory molecules that control the proinflammatory cytokine response. The nature of anti-inflammatory cytokines and soluble cytokine receptors is the focus of the current study. The current and future therapeutic uses of these anti-inflammatory cytokines are also paid attention to.

Cytokines act in concert with specific cytokine inhibitors and soluble cytokine receptors to regulate the human immune response. Their physiologic role in inflammation and pathologic role in systemic inflammatory states are increasingly recognized. Major anti-inflammatory cytokines include interleukin (IL)-1 receptor antagonist, IL-4, IL-6, IL-10, IL-11, and IL-13. Specific cytokine receptors for IL-1, tumor necrosis factor-α, and IL-18 also function as proinflammatory cytokine inhibitors. And cytokines such as IL-10, IL-4, and IL-12 are involved in reducing inflammatory reactions.

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