PRNP cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	PRNP
Entrez Gene ID	396452
Full Name	prion protein
Synonyms	Prn-p,prp
General protein information	Preferred Names prion protein Names major prion protein homolog 65-21 protein ARIA PR-LP acetylcholine receptor-inducing activity prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) prion-like-protein
Gene Type	protein-coding
Organism	Gallus gallus(chicken)
Summary	This gene encodes a membrane glycosylphosphatidylinositol-anchored glycoprotein found in the central nervous system. In human and other vertebrates, the homologous protein is associated with neurodegenerative diseases that result from improper protein metabolism. [provided by RefSeq, Nov 2012].

mRNA and Protein(s)

mRNA	Protein	Name
NM_205465.2	NP_990796.2	major prion protein homolog preproprotein
XM_015297300.1	XP_015152786.1	major prion protein homolog isoform X1
XM_015297300.2	XP_015152786.1	major prion protein homolog isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PRNP	NP_990796.2
Xenopus tropicalis (tropical clawed frog)	prnp	NP_001121414.1

Gene Ontology
Bibliography

Related articles in PubMed

An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein.
Vanderperre B, Staskevicius AB, Tremblay G, McCoy M, O'Neill MA, Cashman NR, Roucou X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(7)2373-86(2011 Jul)

Distribution of the cellular prion protein in the central nervous system of the chicken.
Atoji Y, Ishiguro N
Journal of chemical neuroanatomy38(4)292-301(2009 Dec)

A comparative molecular dynamics study on thermostability of human and chicken prion proteins.
Ji HF, Zhang HY
Biochemical and biophysical research communications359(3)790-4(2007 Aug)

Comparative genomic analysis of prion genes.
Premzl M, Gamulin V
BMC genomics81(2007 Jan)

Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index.
Carre W, Wang X, Porter TE, Nys Y, Tang J, Bernberg E, Morgan R, Burnside J, Aggrey SE, Simon J, Cogburn LA
Physiological genomics25(3)514-24(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings suggest that PrP in the chicken CNS is localized in the dendrites and axons of neurons and that it is associated with certain sensory systems.
Title: Distribution of the cellular prion protein in the central nervous system of the chicken.

thermostability of Human PrP(C) is comparable with that of chicken PrP(C)
Title: A comparative molecular dynamics study on thermostability of human and chicken prion proteins.

PrP was found to be very similar to the mammalian protein, although there is only 30% homology in the secondary structure; hexapeptide repeats might bind copper ions in two different ways, depending on the number of repeats and metal/ligand molar ratio
Title: Structure and stability of the CuII complexes with tandem repeats of the chicken prion.

Data show that structure and coordination of human prion protein (PrP) copper binding sites are conserved in the pH 6.5-7.4 range, and that chicken PrP hexarepeat motifs display homologous Cu(II) coordination at sub-stoichiometric copper concentrations.
Title: Comparative analysis of the human and chicken prion protein copper binding regions at pH 6.5.

Similar to human octapeptide fragments, chicken tandem repeats exhibit a cooperative effect in binding Cu(2+) ions, although chicken peptides are much less effective in metal ion coordination
Title: Interactions of Cu2+ ions with chicken prion tandem repeats.

The following PRNP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRNP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OGa24922	NM_205465.2 Latest version!	Gallus gallus prion protein (PRNP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00
OGa24922	XM_015297300.2 Latest version!	Gallus gallus prion protein (PRNP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00
View Old Accession Versions >>
OGa24922	XM_015297300.1	Gallus gallus prion protein (PRNP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PRNP ( NM_205465.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990796.2 Gallus gallus prion protein (PRNP), mRNA.

Price & Availability↑

CloneID	OGa24922
Clone ID Related Accession (Same CDS sequence)	NM_205465.2 , XM_015297300.1 , XM_015297300.2
Accession Version	NM_205465.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Gallus gallus(chicken)
Product	major prion protein homolog preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ450048.1, M61145.1, BU137735.1 and BI067124.1. On Nov 22, 2012 this sequence version replaced NM_205465.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M61145.1, CN226000.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCTAGGC TCCTCACCAC CTGCTGCCTG CTGGCCCTGC TGCTCGCCGC CTGCACCGAC 
GTCGCCCTCT CCAAGAAGGG CAAAGGCAAA CCCAGTGGTG GGGGTTGGGG CGCCGGGAGC 
CATCGCCAGC CCAGCTACCC CCGCCAGCCG GGCTACCCTC ATAACCCAGG GTACCCCCAT 
AACCCAGGGT ACCCCCATAA CCCAGGGTAC CCCCACAACC CTGGCTATCC CCATAACCCC 
GGCTACCCCC AGAACCCTGG CTACCCCCAT AACCCAGGTT ACCCAGGCTG GGGTCAAGGC 
TACAACCCAT CCAGCGGAGG AAGTTACCAC AACCAGAAGC CATGGAAACC CCCCAAAACC 
AACTTCAAGC ACGTGGCGGG GGCAGCAGCG GCGGGTGCTG TGGTGGGGGG CTTGGGGGGC 
TACGCCATGG GGCGCGTTAT GTCAGGGATG AACTACCACT TCGATAGCCC CGATGAGTAC 
CGATGGTGGA GTGAGAACTC GGCGCGTTAT CCCAACCGGG TTTACTACCG GGATTACAGC 
AGCCCCGTGC CACAGGACGT CTTCGTGGCC GATTGCTTTA ACATCACAGT GACTGAGTAC 
AGCATTGGCC CTGCTGCCAA GAAGAACACC TCCGAGGCTG TGGCGGCAGC AAACCAAACG 
GAGGTGGAGA TGGAGAACAA AGTGGTGACG AAGGTGATCC GCGAGATGTG CGTGCAGCAG 
TACCGCGAGT ACCGCCTGGC CTCGGGCATC CAGCTGCACC CTGCTGACAC CTGGCTCGCC 
GTCCTCCTCC TCCTCCTCAC CACCCTTTTT GCCATGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990796.2
CDS	216..1037
Translation	MARLLTTCCLLALLLAACTDVALSKKGKGKPSGGGWGAGSHRQPSYPRQPGYPHNPGYPHNPGYPHNPGYPHNPGYPHNPGYPQNPGYPHNPGYPGWGQGYNPSSGGSYHNQKPWKPPKTNFKHVAGAAAAGAVVGGLGGYAMGRVMSGMNYHFDSPDEYRWWSENSARYPNRVYYRDYSSPVPQDVFVADCFNITVTEYSIGPAAKKNTSEAVAAANQTEVEMENKVVTKVIREMCVQQYREYRLASGIQLHPADTWLAVLLLLLTTLFAMH

Target ORF information:

RefSeq Version	NM_205465.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus prion protein (PRNP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205465.2

ORF Insert Sequence:

ATGGCTAGGC TCCTCACCAC CTGCTGCCTG CTGGCCCTGC TGCTCGCCGC CTGCACCGAC 
GTCGCCCTCT CCAAGAAGGG CAAAGGCAAA CCCAGTGGTG GGGGTTGGGG CGCCGGGAGC 
CATCGCCAGC CCAGCTACCC CCGCCAGCCG GGCTACCCTC ATAACCCAGG GTACCCCCAT 
AACCCAGGGT ACCCCCATAA CCCAGGGTAC CCCCACAACC CTGGCTATCC CCATAACCCC 
GGCTACCCCC AGAACCCTGG CTACCCCCAT AACCCAGGTT ACCCAGGCTG GGGTCAAGGC 
TACAACCCAT CCAGCGGAGG AAGTTACCAC AACCAGAAGC CATGGAAACC CCCCAAAACC 
AACTTCAAGC ACGTGGCGGG GGCAGCAGCG GCGGGTGCTG TGGTGGGGGG CTTGGGGGGC 
TACGCCATGG GGCGCGTTAT GTCAGGGATG AACTACCACT TCGATAGCCC CGATGAGTAC 
CGATGGTGGA GTGAGAACTC GGCGCGTTAT CCCAACCGGG TTTACTACCG GGATTACAGC 
AGCCCCGTGC CACAGGACGT CTTCGTGGCC GATTGCTTTA ACATCACAGT GACTGAGTAC 
AGCATTGGCC CTGCTGCCAA GAAGAACACC TCCGAGGCTG TGGCGGCAGC AAACCAAACG 
GAGGTGGAGA TGGAGAACAA AGTGGTGACG AAGGTGATCC GCGAGATGTG CGTGCAGCAG 
TACCGCGAGT ACCGCCTGGC CTCGGGCATC CAGCTGCACC CTGCTGACAC CTGGCTCGCC 
GTCCTCCTCC TCCTCCTCAC CACCCTTTTT GCCATGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( XM_015297300.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015152786.1 Gallus gallus prion protein (PRNP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa24922
Clone ID Related Accession (Same CDS sequence)	NM_205465.2 , XM_015297300.1 , XM_015297300.2
Accession Version	XM_015297300.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-03
Organism	Gallus gallus(chicken)
Product	major prion protein homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_455997.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTAGGC TCCTCACCAC CTGCTGCCTG CTGGCCCTGC TGCTCGCCGC CTGCACCGAC 
GTCGCCCTCT CCAAGAAGGG CAAAGGCAAA CCCAGTGGTG GGGGTTGGGG CGCCGGGAGC 
CATCGCCAGC CCAGCTACCC CCGCCAGCCG GGCTACCCTC ATAACCCAGG GTACCCCCAT 
AACCCAGGGT ACCCCCATAA CCCAGGGTAC CCCCACAACC CTGGCTATCC CCATAACCCC 
GGCTACCCCC AGAACCCTGG CTACCCCCAT AACCCAGGTT ACCCAGGCTG GGGTCAAGGC 
TACAACCCAT CCAGCGGAGG AAGTTACCAC AACCAGAAGC CATGGAAACC CCCCAAAACC 
AACTTCAAGC ACGTGGCGGG GGCAGCAGCG GCGGGTGCTG TGGTGGGGGG CTTGGGGGGC 
TACGCCATGG GGCGCGTTAT GTCAGGGATG AACTACCACT TCGATAGCCC CGATGAGTAC 
CGATGGTGGA GTGAGAACTC GGCGCGTTAT CCCAACCGGG TTTACTACCG GGATTACAGC 
AGCCCCGTGC CACAGGACGT CTTCGTGGCC GATTGCTTTA ACATCACAGT GACTGAGTAC 
AGCATTGGCC CTGCTGCCAA GAAGAACACC TCCGAGGCTG TGGCGGCAGC AAACCAAACG 
GAGGTGGAGA TGGAGAACAA AGTGGTGACG AAGGTGATCC GCGAGATGTG CGTGCAGCAG 
TACCGCGAGT ACCGCCTGGC CTCGGGCATC CAGCTGCACC CTGCTGACAC CTGGCTCGCC 
GTCCTCCTCC TCCTCCTCAC CACCCTTTTT GCCATGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015152786.1
CDS	274..1095
Translation	MARLLTTCCLLALLLAACTDVALSKKGKGKPSGGGWGAGSHRQPSYPRQPGYPHNPGYPHNPGYPHNPGYPHNPGYPHNPGYPQNPGYPHNPGYPGWGQGYNPSSGGSYHNQKPWKPPKTNFKHVAGAAAAGAVVGGLGGYAMGRVMSGMNYHFDSPDEYRWWSENSARYPNRVYYRDYSSPVPQDVFVADCFNITVTEYSIGPAAKKNTSEAVAAANQTEVEMENKVVTKVIREMCVQQYREYRLASGIQLHPADTWLAVLLLLLTTLFAMH

Target ORF information:

RefSeq Version	XM_015297300.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus prion protein (PRNP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015297300.1

ORF Insert Sequence:

ATGGCTAGGC TCCTCACCAC CTGCTGCCTG CTGGCCCTGC TGCTCGCCGC CTGCACCGAC 
GTCGCCCTCT CCAAGAAGGG CAAAGGCAAA CCCAGTGGTG GGGGTTGGGG CGCCGGGAGC 
CATCGCCAGC CCAGCTACCC CCGCCAGCCG GGCTACCCTC ATAACCCAGG GTACCCCCAT 
AACCCAGGGT ACCCCCATAA CCCAGGGTAC CCCCACAACC CTGGCTATCC CCATAACCCC 
GGCTACCCCC AGAACCCTGG CTACCCCCAT AACCCAGGTT ACCCAGGCTG GGGTCAAGGC 
TACAACCCAT CCAGCGGAGG AAGTTACCAC AACCAGAAGC CATGGAAACC CCCCAAAACC 
AACTTCAAGC ACGTGGCGGG GGCAGCAGCG GCGGGTGCTG TGGTGGGGGG CTTGGGGGGC 
TACGCCATGG GGCGCGTTAT GTCAGGGATG AACTACCACT TCGATAGCCC CGATGAGTAC 
CGATGGTGGA GTGAGAACTC GGCGCGTTAT CCCAACCGGG TTTACTACCG GGATTACAGC 
AGCCCCGTGC CACAGGACGT CTTCGTGGCC GATTGCTTTA ACATCACAGT GACTGAGTAC 
AGCATTGGCC CTGCTGCCAA GAAGAACACC TCCGAGGCTG TGGCGGCAGC AAACCAAACG 
GAGGTGGAGA TGGAGAACAA AGTGGTGACG AAGGTGATCC GCGAGATGTG CGTGCAGCAG 
TACCGCGAGT ACCGCCTGGC CTCGGGCATC CAGCTGCACC CTGCTGACAC CTGGCTCGCC 
GTCCTCCTCC TCCTCCTCAC CACCCTTTTT GCCATGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( XM_015297300.2 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015152786.1 Gallus gallus prion protein (PRNP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa24922
Clone ID Related Accession (Same CDS sequence)	NM_205465.2 , XM_015297300.1 , XM_015297300.2
Accession Version	XM_015297300.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-16
Organism	Gallus gallus(chicken)
Product	major prion protein homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006109.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015297300.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTAGGC TCCTCACCAC CTGCTGCCTG CTGGCCCTGC TGCTCGCCGC CTGCACCGAC 
GTCGCCCTCT CCAAGAAGGG CAAAGGCAAA CCCAGTGGTG GGGGTTGGGG CGCCGGGAGC 
CATCGCCAGC CCAGCTACCC CCGCCAGCCG GGCTACCCTC ATAACCCAGG GTACCCCCAT 
AACCCAGGGT ACCCCCATAA CCCAGGGTAC CCCCACAACC CTGGCTATCC CCATAACCCC 
GGCTACCCCC AGAACCCTGG CTACCCCCAT AACCCAGGTT ACCCAGGCTG GGGTCAAGGC 
TACAACCCAT CCAGCGGAGG AAGTTACCAC AACCAGAAGC CATGGAAACC CCCCAAAACC 
AACTTCAAGC ACGTGGCGGG GGCAGCAGCG GCGGGTGCTG TGGTGGGGGG CTTGGGGGGC 
TACGCCATGG GGCGCGTTAT GTCAGGGATG AACTACCACT TCGATAGCCC CGATGAGTAC 
CGATGGTGGA GTGAGAACTC GGCGCGTTAT CCCAACCGGG TTTACTACCG GGATTACAGC 
AGCCCCGTGC CACAGGACGT CTTCGTGGCC GATTGCTTTA ACATCACAGT GACTGAGTAC 
AGCATTGGCC CTGCTGCCAA GAAGAACACC TCCGAGGCTG TGGCGGCAGC AAACCAAACG 
GAGGTGGAGA TGGAGAACAA AGTGGTGACG AAGGTGATCC GCGAGATGTG CGTGCAGCAG 
TACCGCGAGT ACCGCCTGGC CTCGGGCATC CAGCTGCACC CTGCTGACAC CTGGCTCGCC 
GTCCTCCTCC TCCTCCTCAC CACCCTTTTT GCCATGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015152786.1
CDS	283..1104
Translation	MARLLTTCCLLALLLAACTDVALSKKGKGKPSGGGWGAGSHRQPSYPRQPGYPHNPGYPHNPGYPHNPGYPHNPGYPHNPGYPQNPGYPHNPGYPGWGQGYNPSSGGSYHNQKPWKPPKTNFKHVAGAAAAGAVVGGLGGYAMGRVMSGMNYHFDSPDEYRWWSENSARYPNRVYYRDYSSPVPQDVFVADCFNITVTEYSIGPAAKKNTSEAVAAANQTEVEMENKVVTKVIREMCVQQYREYRLASGIQLHPADTWLAVLLLLLTTLFAMH

Target ORF information:

RefSeq Version	XM_015297300.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus prion protein (PRNP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015297300.2

ORF Insert Sequence:

ATGGCTAGGC TCCTCACCAC CTGCTGCCTG CTGGCCCTGC TGCTCGCCGC CTGCACCGAC 
GTCGCCCTCT CCAAGAAGGG CAAAGGCAAA CCCAGTGGTG GGGGTTGGGG CGCCGGGAGC 
CATCGCCAGC CCAGCTACCC CCGCCAGCCG GGCTACCCTC ATAACCCAGG GTACCCCCAT 
AACCCAGGGT ACCCCCATAA CCCAGGGTAC CCCCACAACC CTGGCTATCC CCATAACCCC 
GGCTACCCCC AGAACCCTGG CTACCCCCAT AACCCAGGTT ACCCAGGCTG GGGTCAAGGC 
TACAACCCAT CCAGCGGAGG AAGTTACCAC AACCAGAAGC CATGGAAACC CCCCAAAACC 
AACTTCAAGC ACGTGGCGGG GGCAGCAGCG GCGGGTGCTG TGGTGGGGGG CTTGGGGGGC 
TACGCCATGG GGCGCGTTAT GTCAGGGATG AACTACCACT TCGATAGCCC CGATGAGTAC 
CGATGGTGGA GTGAGAACTC GGCGCGTTAT CCCAACCGGG TTTACTACCG GGATTACAGC 
AGCCCCGTGC CACAGGACGT CTTCGTGGCC GATTGCTTTA ACATCACAGT GACTGAGTAC 
AGCATTGGCC CTGCTGCCAA GAAGAACACC TCCGAGGCTG TGGCGGCAGC AAACCAAACG 
GAGGTGGAGA TGGAGAACAA AGTGGTGACG AAGGTGATCC GCGAGATGTG CGTGCAGCAG 
TACCGCGAGT ACCGCCTGGC CTCGGGCATC CAGCTGCACC CTGCTGACAC CTGGCTCGCC 
GTCCTCCTCC TCCTCCTCAC CACCCTTTTT GCCATGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(7)2373-86(2011 Jul)
Vanderperre B,Staskevicius AB,Tremblay G,McCoy M,O'Neill MA,Cashman NR,Roucou X

Distribution of the cellular prion protein in the central nervous system of the chicken.
Journal of chemical neuroanatomy38(4)292-301(2009 Dec)
Atoji Y,Ishiguro N

A comparative molecular dynamics study on thermostability of human and chicken prion proteins.
Biochemical and biophysical research communications359(3)790-4(2007 Aug)
Ji HF,Zhang HY

Comparative genomic analysis of prion genes.
BMC genomics81(2007 Jan)
Premzl M,Gamulin V

Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index.
Physiological genomics25(3)514-24(2006 May)
Carre W,Wang X,Porter TE,Nys Y,Tang J,Bernberg E,Morgan R,Burnside J,Aggrey SE,Simon J,Cogburn LA