fabp3 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	fabp3
Entrez Gene ID	171478
Full Name	fatty acid binding protein 3, muscle and heart
Synonyms	H-FABP,O-FABP,cb889,fabp11
General protein information	Preferred Names fatty acid binding protein 3, muscle and heart Names fatty acid-binding protein, heart fatty acid binding protein 11, oocyte
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_152961.3	NP_694493.1	fatty acid-binding protein, heart

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	fabp3	NP_694493.1
Xenopus tropicalis (tropical clawed frog)	fabp3	NP_001015823.1
Canis lupus familiaris (dog)	FABP3	XP_005617722.1
Mus musculus (house mouse)	Fabp3	NP_034304.1
Gallus gallus (chicken)	FABP3	NP_001026060.1
Bos taurus (cattle)	FABP3	NP_776738.1
Homo sapiens (human)	FABP3	NP_004093.1
Pan troglodytes (chimpanzee)	FABP3	XP_003307987.1
Rattus norvegicus (Norway rat)	Fabp3	NP_077076.1

Gene Ontology
Bibliography

Related articles in PubMed

Exposure to cocaine and its main metabolites altered the protein profile of zebrafish embryos.
Parolini M, Bini L, Magni S, Rizzo A, Ghilardi A, Landi C, Armini A, Del Giacco L, Binelli A
Environmental pollution (Barking, Essex : 1987)232603-614(2018 Jan)

Comparison of proteomic profiles in the zebrafish retina during experimental degeneration and regeneration.
Eastlake K, Heywood WE, Tracey-White D, Aquino E, Bliss E, Vasta GR, Mills K, Khaw PT, Moosajee M, Limb GA
Scientific reports744601(2017 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FABP3 knockdown exhibited significant toxic effects on cardiac development and mitochondrial function, which may be responsible for the knockdown of FABP3-induced apoptosis.
Title: Silencing of FABP3 leads to apoptosis-induced mitochondrial dysfunction and stimulates Wnt signaling in zebrafish.

results indicated that FABP3 knockdown had significant effects on cardiac development, and that dysregulated RA signaling was one of the mechanisms underlying this effect.
Title: Knockdown of FABP3 impairs cardiac development in Zebra?sh through the retinoic acid signaling pathway.

transcription of single copy fabp3 is modulated by dietary fatty acids and clofibrate in a tissue specific fashion.
Title: Tissue-specific transcriptional modulation of fatty acid-binding protein genes, fabp2, fabp3 and fabp6, by fatty acids and the peroxisome proliferator, clofibrate, in zebrafish (Danio rerio).

Differentiation in developmental regulation of zebrafish fabp4 and fabp3 gene transcription suggests distinct functions for these two paralogous genes in vertebrate development
Title: The fabp4 gene of zebrafish (Danio rerio)--genomic homology with the mammalian FABP4 and divergence from the zebrafish fabp3 in developmental expression.

determined the cDNA nucleotide sequence, deduced the amino acid sequence and defined the gene structure for FABP3
Title: Structure, linkage mapping and expression of the heart-type fatty acid-binding protein gene (fabp3 ) from zebrafish (Danio rerio).

The following fabp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the fabp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01064	NM_152961.3 Latest version!	Danio rerio fatty acid binding protein 3, muscle and heart (fabp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

fabp3 ( NM_152961.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_694493.1 Danio rerio fatty acid binding protein 3, muscle and heart (fabp3), mRNA.

Price & Availability↑

CloneID	ODa01064
Clone ID Related Accession (Same CDS sequence)	NM_152961.3
Accession Version	NM_152961.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Danio rerio(zebrafish)
Product	fatty acid-binding protein, heart
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH456910.1 and CT725749.2. On Mar 13, 2014 this sequence version replaced NM_152961.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC049060.1, CK396801.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGACG CTTTTATCGG CACGTGGAAC TTGAAGGAGA GCAAGAATTT CGATGAGTAC 
ATGAAAGGAA TTGGTGTTGG CTTTGCCACG CGCCAAGTTG CCAATATGAC CAAACCCACA 
ACCATCATCT CCAAGGAGGG CGACGTTTTC ACACTTAAAA CCGTCAGCAC TTTCAAATCC 
ACAGAAATCA ATTTCAAACT GGGAGAGGAG TTCGATGAGA CCACTGCAGA TGACCGAAAA 
GTCAAGTCTG TTATAACTTT AGATGGAGGG AAGTTGTTGC ATGTTCAGAA ATGGGACGGT 
AAAGAGACGA CCCTGCTGCG AGAAGTCAGT GACAATAACC TCACTCTGAC GTTGACACTT 
GGCGACATCG TCTCCACACG ACACTACGTG AAAGCAGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694493.1
CDS	115..516
Translation	MADAFIGTWNLKESKNFDEYMKGIGVGFATRQVANMTKPTTIISKEGDVFTLKTVSTFKSTEINFKLGEEFDETTADDRKVKSVITLDGGKLLHVQKWDGKETTLLREVSDNNLTLTLTLGDIVSTRHYVKAE

Target ORF information:

RefSeq Version	NM_152961.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio fatty acid binding protein 3, muscle and heart (fabp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152961.3

ORF Insert Sequence:

ATGGCAGACG CTTTTATCGG CACGTGGAAC TTGAAGGAGA GCAAGAATTT CGATGAGTAC 
ATGAAAGGAA TTGGTGTTGG CTTTGCCACG CGCCAAGTTG CCAATATGAC CAAACCCACA 
ACCATCATCT CCAAGGAGGG CGACGTTTTC ACACTTAAAA CCGTCAGCAC TTTCAAATCC 
ACAGAAATCA ATTTCAAACT GGGAGAGGAG TTCGATGAGA CCACTGCAGA TGACCGAAAA 
GTCAAGTCTG TTATAACTTT AGATGGAGGG AAGTTGTTGC ATGTTCAGAA ATGGGACGGT 
AAAGAGACGA CCCTGCTGCG AGAAGTCAGT GACAATAACC TCACTCTGAC GTTGACACTT 
GGCGACATCG TCTCCACACG ACACTACGTG AAAGCAGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exposure to cocaine and its main metabolites altered the protein profile of zebrafish embryos.
Environmental pollution (Barking, Essex : 1987)232603-614(2018 Jan)
Parolini M,Bini L,Magni S,Rizzo A,Ghilardi A,Landi C,Armini A,Del Giacco L,Binelli A

Comparison of proteomic profiles in the zebrafish retina during experimental degeneration and regeneration.
Scientific reports744601(2017 Mar)
Eastlake K,Heywood WE,Tracey-White D,Aquino E,Bliss E,Vasta GR,Mills K,Khaw PT,Moosajee M,Limb GA

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fabp3 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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