Gene Symbol | ak2 |
Entrez Gene ID | 321793 |
Full Name | adenylate kinase 2 |
Synonyms | wu:fb34f05,wu:fj80e03 |
General protein information |
|
Gene Type | protein-coding |
Organism | Danio rerio(zebrafish) |
ORF » Species Summary » Danio rerio » ak2 cDNA ORF clone
gRNAs
Gene Symbol | ak2 |
Entrez Gene ID | 321793 |
Full Name | adenylate kinase 2 |
Synonyms | wu:fb34f05,wu:fj80e03 |
General protein information |
|
Gene Type | protein-coding |
Organism | Danio rerio(zebrafish) |
mRNA | Protein | Name |
---|---|---|
NM_212596.1 | NP_997761.1 | adenylate kinase 2, mitochondrial |
XM_005159648.3 | XP_005159705.1 | adenylate kinase 2, mitochondrial isoform X1 |
Homo sapiens (human) | AK2 | NP_001616.1 |
Gallus gallus (chicken) | AK2 | XP_004947909.1 |
Danio rerio (zebrafish) | ak2 | NP_997761.1 |
Oryza sativa (rice) | Os11g0312400 | NP_001067759.1 |
Xenopus tropicalis (tropical clawed frog) | ak2 | NP_001004791.1 |
Canis lupus familiaris (dog) | AK2 | XP_005617670.1 |
Bos taurus (cattle) | AK2 | NP_776314.1 |
Caenorhabditis elegans (roundworm) | let-754 | NP_498730.1 |
Arabidopsis thaliana (thale cress) | ADK1 | NP_201145.1 |
Mus musculus (house mouse) | Ak2 | NP_001029138.1 |
Kluyveromyces lactis | KLLA0F13376g | XP_455682.1 |
Eremothecium gossypii | AGOS_AGR187W | NP_986853.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01058 | XP_003717881.1 |
Arabidopsis thaliana (thale cress) | AT5G50370 | NP_199848.1 |
Oryza sativa (rice) | Os12g0236400 | NP_001066462.1 |
AK2 | XP_001105613.2 | |
Pan troglodytes (chimpanzee) | AK2 | XP_513289.2 |
Rattus norvegicus (Norway rat) | Ak2 | NP_112248.2 |
Drosophila melanogaster (fruit fly) | Adk2 | NP_523836.2 |
Anopheles gambiae (African malaria mosquito) | KAD2_ANOGA | XP_308155.2 |
Saccharomyces cerevisiae (baker's yeast) | ADK1 | NP_010512.1 |
Schizosaccharomyces pombe (fission yeast) | adk1 | NP_593685.1 |
Neurospora crassa | NCU01550 | XP_956253.2 |
Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)
Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)
RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)
Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress.
Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F
The Journal of experimental medicine212(8)1185-202(2015 Jul)
Zebrafish as a model for understanding the evolution of the vertebrate immune system and human primary immunodeficiency.
Iwanami N
Experimental hematology42(8)697-706(2014 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress.
Title: Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress.
Knockdown of zebrafish ak2 also leads to aberrant leukocyte development, stressing the evolutionarily conserved role of AK2.
Title: Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.
The following ak2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ak2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ODa37316 | |
Clone ID Related Accession (Same CDS sequence) | NM_212596.1 | |
Accession Version | NM_212596.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Danio rerio(zebrafish) | |
Product | adenylate kinase 2, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC053160.1. ##Evidence-Data-START## Transcript exon combination :: BC053160.1, EL646213.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGCCCCTA GCACACAAGA GGACGATACC GTCTCCGGTA TACGGAAAGG CATACGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_997761.1 |
CDS | 59..784 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCCCTA GCACACAAGA GGACGATACC GTCTCCGGTA TACGGAAAGG CATACGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ODa24309 | |
Clone ID Related Accession (Same CDS sequence) | XM_005159648.3 | |
Accession Version | XM_005159648.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-06-14 | |
Organism | Danio rerio(zebrafish) | |
Product | adenylate kinase 2, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007130.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005159648.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCCCTA GCACACAAGA GGACGATACC GTCTCCGGTA TACGGAAAGG CATACGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005159705.1 |
CDS | 93..800 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCCCTA GCACACAAGA GGACGATACC GTCTCCGGTA TACGGAAAGG CATACGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Evolution of complexity in the zebrafish synapse proteome. |
Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. |
RFX transcription factors are essential for hearing in mice. |
Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress. |
Zebrafish as a model for understanding the evolution of the vertebrate immune system and human primary immunodeficiency. |