AdSL cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	AdSL
Entrez Gene ID	42051
Full Name	Adenylosuccinate Lyase
Synonyms	CG3590,Dmel\CG3590
General protein information	Preferred Names Adenylosuccinate Lyase Names CG3590 gene product from transcript CG3590-RA AdSL-PA CG3590-PA adenylosuccinate lyase
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 89E8-89E8

mRNA and Protein(s)

mRNA	Protein	Name
NM_142329.4	NP_650586.2	adenylosuccinate lyase

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ADSL	XP_531727.4
Kluyveromyces lactis	KLLA0B13189g	XP_452119.1
Schizosaccharomyces pombe (fission yeast)	ade8	NP_596735.1
Neurospora crassa	NCU06187	XP_962999.2
Mus musculus (house mouse)	Adsl	NP_033764.2
Danio rerio (zebrafish)	adsl	NP_956193.2
Drosophila melanogaster (fruit fly)	CG3590	NP_650586.2
Saccharomyces cerevisiae (baker's yeast)	ADE13	NP_013463.1
Eremothecium gossypii	AGOS_ABL006C	NP_982941.2
Xenopus tropicalis (tropical clawed frog)	adsl	NP_001005457.1
Magnaporthe oryzae (rice blast fungus)	MGG_03645	XP_003716244.1
Homo sapiens (human)	ADSL	NP_000017.1
Pan troglodytes (chimpanzee)	ADSL	XP_003317301.1
Bos taurus (cattle)	ADSL	NP_001095847.1
Gallus gallus (chicken)	ADSL	NP_990860.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002378	XP_312577.3
Rattus norvegicus (Norway rat)	Adsl	NP_001123975.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AdSL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AdSL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa05180	NM_142329.4 Latest version!	Drosophila melanogaster adenylosuccinate lyase (AdSL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AdSL ( NM_142329.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_650586.2 Drosophila melanogaster adenylosuccinate lyase (AdSL), mRNA.

Price & Availability↑

CloneID	OFa05180
Clone ID Related Accession (Same CDS sequence)	NM_142329.4
Accession Version	NM_142329.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1446bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	adenylosuccinate lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_142329.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTAGCA ACTACGAGGG CTACAAGTCG CCGCTGAGCA CCCGGTACGC CAGCAAAGAG 
ATGCAGTTCC TCTTCAGTGA CCAGAACAAG TTCTCCACCT GGCGCCGGTT GTGGGTGTGG 
CTGGCGAAGG CGGAGAGCAG GCTGGGACTA GAGATCAGCG ATGCCCAGAT TGCCGAGATG 
GAGCTCCAGA TCAGCAACAT CGACTTTGAG GCGGCCGCCG CCGAGGAGCG ACTTACGCGC 
CACGACGTAA TGGCCCACGT CCATGTCTTT GCCAAACAGT GTCCCTCTGC TGCGCCGGTG 
ATCCATTTGG GAGCAACCTC GTGCTATGTG GGCGACAACA CTGATCTGAT TGTACTGAGG 
GACGCTCTTA AACTGCTCCT TCCACGAGTC GCCAGCGTGA TAGCTCGTCT AAGCCAGTTT 
GCCCAGAGCT ACAAGGATCA GCCCACGTTG GGATTCACCC ATCTCCAGCC TGCGCAGTTG 
ACCACGGTTG GCAAGCGGGC GTGCCTGTGG ATCCAGGATC TGATCATGGA CGAACGCGCG 
CTGTCCCGCT GTTTAGAGGA CCTGCGCTTC CGTGGAGTCA AGGGAACTAC TGGTACCCAG 
GCCTCGTTCC TGCAACTTTT CAATGGGGAT GGCGAGAAGG TGAAGCAGCT GGATCAGTTG 
GTCACCGAAC TGGCTGGCTT CAAGAAGGCC TATGCGGTAA CCGGTCAAAC ATACTCCCGA 
AAGGTGGATG TGGAGATCGT GGCCGCGCTT GCCAGTCTCG GCACCACCAT CCACAAGATG 
TGCTCCGATC TGCGCATCCT CGCTTCTCGC AAAGAGCTGG AGGAGCCCTT CGAGAGCACT 
CAGATTGGCT CCTCGGCCAT GCCGTACAAG AGGAACCCTA TGCGCTCGGA GCGTTGTTGC 
GCCCTGGCCC GTCACCTCAT CACCTTGTTC AGCAGTGCTG CTAATACACA TGCCACTCAG 
TGGCTGGAAC GCACTCTGGA TGACTCTGCC AACAGGAGGT TGACCCTATC CGAGGCCTTC 
CTGGCTGCAG ATGCCGCCCT GCTTACTCTG CTGAACATCT CGCAGGGACT GGTCGTTTAC 
CCAAAGGTGA TTGAACGGCA CATTTCCCAA GAGCTGCCGT TCATGTCCAC AGAGAACATA 
ATCATGGCCA TGGTGAAGGC GGGAGGAGAT CGCCAGGTGT GCCACGAGAA GATTCGCGTG 
CTGTCCCAGG AGGCCGGAGC CCAGGTGAAG CAGCATGGCA AGGACAACGA CCTCGTGGTT 
CGAGTGCGAA AGGATCCCTA CTTTTCGCCC ATCCTGGAGC AACTGGACAC CATACTGGAT 
GCCAAAACCT TTACTGGACG TGCCAGCGAC CAAGTGGGCG AGTTCGTCAA GGAGGAAGTG 
GAACCCGTGC TGGCACGCTA CTCCGAAGCC CTGAAGAACG TTCAAGACGT CAAACTGAAC 
ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_650586.2
CDS	127..1572
Translation	MASNYEGYKSPLSTRYASKEMQFLFSDQNKFSTWRRLWVWLAKAESRLGLEISDAQIAEMELQISNIDFEAAAAEERLTRHDVMAHVHVFAKQCPSAAPVIHLGATSCYVGDNTDLIVLRDALKLLLPRVASVIARLSQFAQSYKDQPTLGFTHLQPAQLTTVGKRACLWIQDLIMDERALSRCLEDLRFRGVKGTTGTQASFLQLFNGDGEKVKQLDQLVTELAGFKKAYAVTGQTYSRKVDVEIVAALASLGTTIHKMCSDLRILASRKELEEPFESTQIGSSAMPYKRNPMRSERCCALARHLITLFSSAANTHATQWLERTLDDSANRRLTLSEAFLAADAALLTLLNISQGLVVYPKVIERHISQELPFMSTENIIMAMVKAGGDRQVCHEKIRVLSQEAGAQVKQHGKDNDLVVRVRKDPYFSPILEQLDTILDAKTFTGRASDQVGEFVKEEVEPVLARYSEALKNVQDVKLNI

Target ORF information:

RefSeq Version	NM_142329.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster adenylosuccinate lyase (AdSL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_142329.4

ORF Insert Sequence:

ATGGCTAGCA ACTACGAGGG CTACAAGTCG CCGCTGAGCA CCCGGTACGC CAGCAAAGAG 
ATGCAGTTCC TCTTCAGTGA CCAGAACAAG TTCTCCACCT GGCGCCGGTT GTGGGTGTGG 
CTGGCGAAGG CGGAGAGCAG GCTGGGACTA GAGATCAGCG ATGCCCAGAT TGCCGAGATG 
GAGCTCCAGA TCAGCAACAT CGACTTTGAG GCGGCCGCCG CCGAGGAGCG ACTTACGCGC 
CACGACGTAA TGGCCCACGT CCATGTCTTT GCCAAACAGT GTCCCTCTGC TGCGCCGGTG 
ATCCATTTGG GAGCAACCTC GTGCTATGTG GGCGACAACA CTGATCTGAT TGTACTGAGG 
GACGCTCTTA AACTGCTCCT TCCACGAGTC GCCAGCGTGA TAGCTCGTCT AAGCCAGTTT 
GCCCAGAGCT ACAAGGATCA GCCCACGTTG GGATTCACCC ATCTCCAGCC TGCGCAGTTG 
ACCACGGTTG GCAAGCGGGC GTGCCTGTGG ATCCAGGATC TGATCATGGA CGAACGCGCG 
CTGTCCCGCT GTTTAGAGGA CCTGCGCTTC CGTGGAGTCA AGGGAACTAC TGGTACCCAG 
GCCTCGTTCC TGCAACTTTT CAATGGGGAT GGCGAGAAGG TGAAGCAGCT GGATCAGTTG 
GTCACCGAAC TGGCTGGCTT CAAGAAGGCC TATGCGGTAA CCGGTCAAAC ATACTCCCGA 
AAGGTGGATG TGGAGATCGT GGCCGCGCTT GCCAGTCTCG GCACCACCAT CCACAAGATG 
TGCTCCGATC TGCGCATCCT CGCTTCTCGC AAAGAGCTGG AGGAGCCCTT CGAGAGCACT 
CAGATTGGCT CCTCGGCCAT GCCGTACAAG AGGAACCCTA TGCGCTCGGA GCGTTGTTGC 
GCCCTGGCCC GTCACCTCAT CACCTTGTTC AGCAGTGCTG CTAATACACA TGCCACTCAG 
TGGCTGGAAC GCACTCTGGA TGACTCTGCC AACAGGAGGT TGACCCTATC CGAGGCCTTC 
CTGGCTGCAG ATGCCGCCCT GCTTACTCTG CTGAACATCT CGCAGGGACT GGTCGTTTAC 
CCAAAGGTGA TTGAACGGCA CATTTCCCAA GAGCTGCCGT TCATGTCCAC AGAGAACATA 
ATCATGGCCA TGGTGAAGGC GGGAGGAGAT CGCCAGGTGT GCCACGAGAA GATTCGCGTG 
CTGTCCCAGG AGGCCGGAGC CCAGGTGAAG CAGCATGGCA AGGACAACGA CCTCGTGGTT 
CGAGTGCGAA AGGATCCCTA CTTTTCGCCC ATCCTGGAGC AACTGGACAC CATACTGGAT 
GCCAAAACCT TTACTGGACG TGCCAGCGAC CAAGTGGGCG AGTTCGTCAA GGAGGAAGTG 
GAACCCGTGC TGGCACGCTA CTCCGAAGCC CTGAAGAACG TTCAAGACGT CAAACTGAAC 
ATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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AdSL cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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