ort cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	ort
Entrez Gene ID	45910
Full Name	ora transientless
Synonyms	CG7411,CT22815,DMHisClalpha1,Dm-hclA,DmHisCl2,Dmel\CG7411,GluCI,HA-CI I,HclA,HisC12,HisCI2,HisCl,HisCl-alpha1,HisCl2,Hist1,ORT,Ort,hclA,hisCl2,ora
General protein information	Preferred Names ora transientless Names CG7411 gene product from transcript CG7411-RA CG7411-PA Histamine-gated chloride channel subunit 2 glycine receptor alpha2-like histamine-gated chloride channel subunit 1 indefinite ort-PA outer rhabdomere absent outer rhabdomeres absent outer rhabdomeres transientless outer-rhabdomeres-absent
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 92A13-92A13\|3-66.4 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_079682.3	NP_524406.1	ora transientless

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	ort	NP_524406.1
Xenopus tropicalis (tropical clawed frog)	glrb	NP_001072255.1
Homo sapiens (human)	GLRB	NP_000815.1
Pan troglodytes (chimpanzee)	GLRB	XP_517504.1
	GLRB	XP_001093832.1
Bos taurus (cattle)	GLRB	NP_776496.1
Canis lupus familiaris (dog)	GLRB	XP_532701.1
Danio rerio (zebrafish)	glrbb	NP_001003587.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001913	XP_321152.5
Mus musculus (house mouse)	Glrb	NP_034428.2
Rattus norvegicus (Norway rat)	Glrb	NP_445748.1
Gallus gallus (chicken)	GLRB	XP_420379.2
Danio rerio (zebrafish)	glrba	NP_571856.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The native receptor at the synapse of large monopolar cells (LMC) is an hclA homomer that alone is necessary and sufficient to account for the native histamine receptors at the Drosophila photoreceptor-LMC synapse.
Title: Distinct roles for two histamine receptors (hclA and hclB) at the Drosophila photoreceptor synapse.

identified ort as a candidate gene encoding a histamine receptor subunit on laminar neurons, L1/L2
Title: The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA).

The following ort gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ort cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa06905	NM_079682.3 Latest version!	Drosophila melanogaster ora transientless (ort), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ort ( NM_079682.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524406.1 Drosophila melanogaster ora transientless (ort), mRNA.

Price & Availability↑

CloneID	OFa06905
Clone ID Related Accession (Same CDS sequence)	NM_079682.3
Accession Version	NM_079682.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	ora transientless
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_079682.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTGTTCC AAATAATAAT CCTGGTGATC TGCACCATCT GCATGAAGCA CTACGCCAAA 
GGGGAGTTTC AACAAAGTCT GGCCATAACC GACATCCTGC CCGAGGACAT CAAGCGTTAC 
GACAAGATGA GACCGCCGAA GAAAGAGGGT CAGCCGACGA TAGTCTACTT CCATGTGACG 
GTGATGGGTC TGGACTCCAT TGATGAGAAC TCGATGACTT ATGTGGCGGA TGTGTTCTTT 
GCACAGACGT GGAAGGATCA TCGCCTGCGA TTGCCGGAGA ATATGACACA GGAATACCGC 
CTGCTCGAGG TGGACTGGCT AAAAAATATG TGGCGGCCGG ATTCGTTTTT CAAAAACGCC 
AAATCGGTGA CCTTTCAGAC CATGACAATA CCCAATCACT ATATGTGGCT GTACAAGGAT 
AAGACCATTC TGTACATGGT CAAACTAACA CTGAAGCTGT CCTGCATCAT GAACTTCGCC 
ATTTATCCTC ATGATACACA GGAGTGCAAG CTGCAAATGG AAAGCCTGTC CCACACCACG 
GATGACTTGA TATTCCAGTG GGATCCAACA ACGCCCCTTG TGGTTGATGA AAACATCGAA 
CTGCCGCAGG TGGCCCTCAT CCGAAATGAA ACGGCGGACT GTACCCAAGT TTATTCCACT 
GGCAACTTCA CATGCCTGGA GGTGGTGTTC ACCCTTAAGC GTCGTTTGGT TTACTACGTT 
TTCAACACCT ACATTCCCAC CTGCATGATA GTGATCATGT CATGGGTATC CTTCTGGATC 
AAACCGGAGG CGGCACCAGC CCGTGTGACT CTGGGTGTCA CCTCCTTGCT AACGCTTTCC 
ACGCAACACG CCAAATCGCA GTCGTCTTTG CCACCTGTTT CCTATCTCAA GGCAGTGGAC 
GCCTTTATGT CCGTTTGCAC GGTGTTCGTG TTTATGGCCC TCATGGAGTA TTGTCTAATA 
AACATCGTCC TGAGCGACAC GCCCATTCCC AAGCCGATGG CCTATCCACC CAAACCTGTG 
GCGGGAGATG GGCCCAAGAA AGAGGGCGAG GGTGCTCCTC CTGGGGGCAG CAACTCGACG 
GCCAGCAAGC AACAAGCCAC CATGTTGCCA CTGGCCGATG AAAAGATCGA GAAAATTGAG 
AAGATCTTTG ACGAGATGAC CAAGAATAGA AGGATTGTAA CCACCACACG CCGCGTGGTG 
CGTCCGCCAT TGGACGCCGA TGGTCCGTGG ATTCCGCGAC AGGAGTCGCG GATAATACTG 
ACCCCGACTA TCGCTCCGCC GCCACCGCCC CCTCAGCCAG CGGCACCGGA ACCGGAACTG 
CCCAAGCCGA AACTCACACC CGCCCAGGAG CGGCTCAAGC GGGCTATATA TATAGATCGG 
TCCTCGCGCG TCCTTTTCCC CGCCCTCTTC GCCAGTCTGA ATGGCATCTA CTGGTGTGTG 
TTCTACGAGT ATCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524406.1
CDS	349..1806
Translation	MVFQIIILVICTICMKHYAKGEFQQSLAITDILPEDIKRYDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVFYEYL

Target ORF information:

RefSeq Version	NM_079682.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster ora transientless (ort), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079682.3

ORF Insert Sequence:

ATGGTGTTCC AAATAATAAT CCTGGTGATC TGCACCATCT GCATGAAGCA CTACGCCAAA 
GGGGAGTTTC AACAAAGTCT GGCCATAACC GACATCCTGC CCGAGGACAT CAAGCGTTAC 
GACAAGATGA GACCGCCGAA GAAAGAGGGT CAGCCGACGA TAGTCTACTT CCATGTGACG 
GTGATGGGTC TGGACTCCAT TGATGAGAAC TCGATGACTT ATGTGGCGGA TGTGTTCTTT 
GCACAGACGT GGAAGGATCA TCGCCTGCGA TTGCCGGAGA ATATGACACA GGAATACCGC 
CTGCTCGAGG TGGACTGGCT AAAAAATATG TGGCGGCCGG ATTCGTTTTT CAAAAACGCC 
AAATCGGTGA CCTTTCAGAC CATGACAATA CCCAATCACT ATATGTGGCT GTACAAGGAT 
AAGACCATTC TGTACATGGT CAAACTAACA CTGAAGCTGT CCTGCATCAT GAACTTCGCC 
ATTTATCCTC ATGATACACA GGAGTGCAAG CTGCAAATGG AAAGCCTGTC CCACACCACG 
GATGACTTGA TATTCCAGTG GGATCCAACA ACGCCCCTTG TGGTTGATGA AAACATCGAA 
CTGCCGCAGG TGGCCCTCAT CCGAAATGAA ACGGCGGACT GTACCCAAGT TTATTCCACT 
GGCAACTTCA CATGCCTGGA GGTGGTGTTC ACCCTTAAGC GTCGTTTGGT TTACTACGTT 
TTCAACACCT ACATTCCCAC CTGCATGATA GTGATCATGT CATGGGTATC CTTCTGGATC 
AAACCGGAGG CGGCACCAGC CCGTGTGACT CTGGGTGTCA CCTCCTTGCT AACGCTTTCC 
ACGCAACACG CCAAATCGCA GTCGTCTTTG CCACCTGTTT CCTATCTCAA GGCAGTGGAC 
GCCTTTATGT CCGTTTGCAC GGTGTTCGTG TTTATGGCCC TCATGGAGTA TTGTCTAATA 
AACATCGTCC TGAGCGACAC GCCCATTCCC AAGCCGATGG CCTATCCACC CAAACCTGTG 
GCGGGAGATG GGCCCAAGAA AGAGGGCGAG GGTGCTCCTC CTGGGGGCAG CAACTCGACG 
GCCAGCAAGC AACAAGCCAC CATGTTGCCA CTGGCCGATG AAAAGATCGA GAAAATTGAG 
AAGATCTTTG ACGAGATGAC CAAGAATAGA AGGATTGTAA CCACCACACG CCGCGTGGTG 
CGTCCGCCAT TGGACGCCGA TGGTCCGTGG ATTCCGCGAC AGGAGTCGCG GATAATACTG 
ACCCCGACTA TCGCTCCGCC GCCACCGCCC CCTCAGCCAG CGGCACCGGA ACCGGAACTG 
CCCAAGCCGA AACTCACACC CGCCCAGGAG CGGCTCAAGC GGGCTATATA TATAGATCGG 
TCCTCGCGCG TCCTTTTCCC CGCCCTCTTC GCCAGTCTGA ATGGCATCTA CTGGTGTGTG 
TTCTACGAGT ATCTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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ort cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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Target ORF information:

ORF Insert Sequence:

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