Gene Symbol | BCL6 |
Entrez Gene ID | 424912 |
Full Name | B-cell CLL/lymphoma 6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Gallus gallus(chicken) |
ORF » Species Summary » Gallus gallus » BCL6 cDNA ORF clone
gRNAs
Gene Symbol | BCL6 |
Entrez Gene ID | 424912 |
Full Name | B-cell CLL/lymphoma 6 |
General protein information |
|
Gene Type | protein-coding |
Organism | Gallus gallus(chicken) |
mRNA | Protein | Name |
---|---|---|
XM_015291406.2 | XP_015146892.1 | B-cell lymphoma 6 protein homolog isoform X1 |
XM_015291406.1 | XP_015146892.1 | B-cell lymphoma 6 protein homolog isoform X1 |
XM_025153369.1 | XP_025009137.1 | B-cell lymphoma 6 protein homolog isoform X1 |
NM_001012930.1 | NP_001012948.1 | B-cell lymphoma 6 protein homolog |
Bos taurus (cattle) | BCL6 | NP_001193379.1 |
Pan troglodytes (chimpanzee) | BCL6 | XP_001158812.1 |
Canis lupus familiaris (dog) | BCL6 | NP_001182333.1 |
Danio rerio (zebrafish) | bcl6a | NP_957028.1 |
Gallus gallus (chicken) | BCL6 | NP_001012948.1 |
Homo sapiens (human) | BCL6 | NP_001124317.1 |
BCL6 | XP_001103860.1 | |
Mus musculus (house mouse) | Bcl6 | NP_033874.1 |
Rattus norvegicus (Norway rat) | Bcl6 | NP_001100554.1 |
Xenopus tropicalis (tropical clawed frog) | bcl6 | NP_001116278.1 |
Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation.
Alinikula J, Nera KP, Junttila S, Lassila O
European journal of immunology41(8)2404-13(2011 Aug)
STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas.
Walker SR, Nelson EA, Frank DA
Oncogene26(2)224-33(2007 Jan)
Bcl6 regulates Th2 type cytokine productions by mast cells activated by FcepsilonRI/IgE cross-linking.
Ohtsuka Y, Arima M, Fujimura L, Li H, Sakamoto A, Okamoto Y, Tokuhisa T
Molecular immunology42(12)1453-9(2005 Aug)
BCL6 suppresses RhoA activity to alter macrophage morphology and motility.
Pixley FJ, Xiong Y, Yu RY, Sahai EA, Stanley ER, Ye BH
Journal of cell science118(Pt 9)1873-83(2005 May)
Abnormal erythroid differentiation in neonatal bcl-6-deficient mice.
Asari S, Sakamoto A, Okada S, Ohkubo Y, Arima M, Hatano M, Kuroda Y, Tokuhisa T
Experimental hematology33(1)26-34(2005 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Findings reveal a complex regulatory network in which Bcl6 acts as a key element dictating the transition of DT40 B cells to plasma cells.
Title: Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation.
The following BCL6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BCL6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OGa27851 | |
Clone ID Related Accession (Same CDS sequence) | NM_001012930.1 | |
Accession Version | NM_001012930.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-21 | |
Organism | Gallus gallus(chicken) | |
Product | B-cell lymphoma 6 protein homolog | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ719545.1. On Mar 14, 2005 this sequence version replaced XM_422722.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ719545.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001012948.1 |
CDS | 108..2234 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OGa39894 | |
Clone ID Related Accession (Same CDS sequence) | XM_015291406.2 , XM_015291406.1 , XM_025153369.1 | |
Accession Version | XM_015291406.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-16 | |
Organism | Gallus gallus(chicken) | |
Product | B-cell lymphoma 6 protein homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006096.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015291406.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015146892.1 |
CDS | 127..2253 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OGa39894 | |
Clone ID Related Accession (Same CDS sequence) | XM_015291406.2 , XM_015291406.1 , XM_025153369.1 | |
Accession Version | XM_015291406.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-03 | |
Organism | Gallus gallus(chicken) | |
Product | B-cell lymphoma 6 protein homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_455915.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015146892.1 |
CDS | 119..2245 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OGa39894 | |
Clone ID Related Accession (Same CDS sequence) | XM_015291406.2 , XM_015291406.1 , XM_025153369.1 | |
Accession Version | XM_025153369.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-16 | |
Organism | Gallus gallus(chicken) | |
Product | B-cell lymphoma 6 protein homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006096.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_025009137.1 |
CDS | 129..2255 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTCAC CGGCAGACAG CTGCATCCAG TTCACCCGCC ACGCAAGCGA TGTCCTCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation. |
STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. |
Bcl6 regulates Th2 type cytokine productions by mast cells activated by FcepsilonRI/IgE cross-linking. |
BCL6 suppresses RhoA activity to alter macrophage morphology and motility. |
Abnormal erythroid differentiation in neonatal bcl-6-deficient mice. |