• English
  • Sign In
    Please Sign In
    Sign In
    New to GenScript?
    Register
  • Contact Us
×
Contact us now: +1-877-436-7274

AASS cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol AASS
Entrez Gene ID 10157
Full Name aminoadipate-semialdehyde synthase
Synonyms LKR/SDH,LKRSDH,LORSDH
General protein information
Preferred Names

aminoadipate-semialdehyde synthase

Names

alpha-aminoadipic semialdehyde synthase, mitochondrial
alpha-aminoadipate semialdehyde synthase
aminoadipic semialdehyde synthase
lysine-2-oxoglutarate reductase
lysine-ketoglutarate reductase /saccharopine dehydrogenase
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

7

7q31.32
Summary This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008].
Disorder MIM:

605113

Disorder Html: Hyperlysinemia, 238700 (3); Saccharopinuria, 268700 (1)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_005763.3 NP_005754.2 alpha-aminoadipic semialdehyde synthase, mitochondrial
XM_011515725.2 XP_011514027.1 alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1
NM_005763.4 NP_005754.2 alpha-aminoadipic semialdehyde synthase, mitochondrial

Pathways from BioSystems


Homologies


AASS XP_002803495.1
Canis lupus familiaris (dog) AASS XP_005628825.1
Bos taurus (cattle) AASS NP_001103267.1
Rattus norvegicus (Norway rat) Aass NP_001094433.1
Magnaporthe oryzae (rice blast fungus) MGG_17041 XP_003716085.1
Arabidopsis thaliana (thale cress) AT4G33150 NP_567914.1
Homo sapiens (human) AASS NP_005754.2
Gallus gallus (chicken) AASS XP_416001.2
Schizosaccharomyces pombe (fission yeast) SPBC3B8.03 NP_596411.1
Oryza sativa (rice) Os02g0783700 NP_001048324.1
Pan troglodytes (chimpanzee) AASS XP_001145257.1
Caenorhabditis elegans (roundworm) CELE_R02D3.1 NP_499884.1
Neurospora crassa NCU03748 XP_961095.2
Xenopus tropicalis (tropical clawed frog) aass NP_001011437.1
Mus musculus (house mouse) Aass NP_038958.2
Danio rerio (zebrafish) aass NP_001167456.1
Drosophila melanogaster (fruit fly) LKR NP_609150.2
Anopheles gambiae (African malaria mosquito) AgaP_AGAP008632 XP_314728.3
Saccharomyces cerevisiae (baker's yeast) LYS9 NP_014448.1
Kluyveromyces lactis KLLA0C18744g XP_453035.1

Gene Ontology


Bibliography

Related articles in PubMed

Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops.
Sasse SK, Zuo Z, Kadiyala V, Zhang L, Pufall MA, Jain MK, Phang TL, Stormo GD, Gerber AN
The Journal of biological chemistry290(32)19756-69(2015 Aug)

Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia.
Houten SM, Denis S, Te Brinke H, Jongejan A, van Kampen AH, Bradley EJ, Baas F, Hennekam RC, Millington DS, Young SP, Frazier DM, Gucsavas-Calikoglu M, Wanders RJ
Human molecular genetics23(18)5009-16(2014 Sep)

Genetic basis of hyperlysinemia.
Houten SM, Te Brinke H, Denis S, Ruiter JP, Knegt AC, de Klerk JB, Augoustides-Savvopoulou P, H?berle J, Baumgartner MR, Co?kun T, Zschocke J, Sass JO, Poll-The BT, Wanders RJ, Duran M
Orphanet journal of rare diseases857(2013 Apr)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia.
Sacksteder KA, Biery BJ, Morrell JC, Goodman BK, Geisbrecht BV, Cox RP, Gould SJ, Geraghty MT
American journal of human genetics66(6)1736-43(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GR and KLF15 physically interact via low affinity GR binding sites within glucocorticoid response elements (GREs) for PRODH and AASS that contribute to combinatorial regulation with KLF15.
Title: Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops.

Mitochondrial NADPH is crucial for AASS function
Title: Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia.

Hyperlysinemia is caused by mutations in AASS
Title: Genetic basis of hyperlysinemia.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Isolation and characterization of the mouse ortholog.
Title: Lysine degradation through the saccharopine pathway in mammals: involvement of both bifunctional and monofunctional lysine-degrading enzymes in mouse.

The following AASS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AASS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu17831 NM_005763.4
Latest version!		 Homo sapiens aminoadipate-semialdehyde synthase (AASS), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $657.30
$939.00
OHu63737 XM_011515725.2
Latest version!		 Homo sapiens aminoadipate-semialdehyde synthase (AASS), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
View Old Accession Versions >>
OHu17831 NM_005763.3 Homo sapiens aminoadipate-semialdehyde synthase (AASS), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $657.30
$939.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu17831
Clone ID Related Accession (Same CDS sequence) NM_005763.3 , NM_005763.4
Accession Version NM_005763.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2781bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-11-27
Organism Homo sapiens(human)
Product alpha-aminoadipic semialdehyde synthase, mitochondrial
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA995180.1, AF229180.1, AC006020.2 and BM669241.1. This sequence is a reference standard in the RefSeqGene project. On Sep 4, 2008 this sequence version replaced NM_005763.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.21373.1, SRR1660809.102574.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
ATGCTGCAAG TACATAGGAC TGGACTGGGC AGGCTGGGGG TCAGCCTCTC CAAGGGTCTT 
CACCACAAAG CTGTGTTGGC CGTCCGGAGG GAGGATGTGA ACGCCTGGGA GAGAAGGGCC 
CCGCTAGCTC CCAAGCACAT CAAAGGCATC ACCAATCTGG GATACAAGGT CTTGATACAG 
CCTTCGAATC GGCGGGCCAT TCATGATAAG GACTATGTCA AAGCTGGTGG CATTCTTCAG 
GAGGATATTT CTGAAGCTTG TCTAATTTTA GGAGTTAAAA GACCTCCAGA GGAAAAATTA 
ATGTCCAGGA AGACTTATGC ATTTTTCTCC CACACAATAA AAGCTCAGGA GGCCAATATG 
GGCTTGTTGG ATGAGATTCT AAAACAGGAA ATTCGCCTTA TTGATTATGA GAAAATGGTG 
GATCATAGAG GAGTACGGGT AGTGGCATTT GGACAGTGGG CTGGTGTGGC AGGAATGATC 
AACATTTTAC ATGGAATGGG TTTAAGGCTC CTTGCTTTGG GACATCACAC ACCTTTTATG 
CACATTGGCA TGGCTCATAA CTACAGGAAT AGCAGTCAGG CTGTGCAAGC TGTCCGTGAT 
GCTGGCTATG AAATATCTTT GGGTTTGATG CCTAAGTCAA TAGGACCCTT AACATTTGTG 
TTCACAGGAA CTGGTAATGT TTCTAAGGGA GCCCAAGCAA TCTTTAATGA GCTACCTTGT 
GAATATGTGG AGCCCCATGA ATTAAAAGAA GTTTCCCAAA CTGGAGACCT CAGAAAAGTG 
TATGGGACGG TGTTAAGTCG TCATCATCAT CTTGTCAGGA AAACAGATGC TGTGTATGAT 
CCTGCAGAGT ATGACAAACA TCCGGAGCGC TACATAAGTC GTTTTAATAC TGATATTGCA 
CCCTATACAA CTTGCTTAAT TAATGGAATC TACTGGGAAC AAAACACTCC TCGCCTCCTA 
ACCCGCCAAG ATGCTCAGAG TCTCCTGGCT CCGGGCAAGT TCTCACCTGC TGGTGTGGAA 
GGCTGCCCTG CATTACCACA CAAACTCGTG GCAATATGTG ACATTTCAGC TGACACAGGA 
GGGTCTATAG AGTTTATGAC TGAGTGTACA ACAATAGAGC ATCCCTTTTG CATGTATGAT 
GCAGACCAGC ATATTATTCA TGACAGTGTT GAAGGCTCGG GGATCCTGAT GTGTTCCATT 
GACAATTTGC CGGCACAGCT CCCAATTGAA GCTACAGAAT GCTTTGGAGA CATGCTTTAC 
CCTTATGTTG AAGAAATGAT ATTATCAGAC GCGACACAGC CTCTTGAAAG TCAGAATTTT 
TCTCCTGTGG TGAGAGATGC AGTGATTACA TCCAACGGTA CATTACCTGA TAAATATAAA 
TATATCCAGA CACTCCGGGA GAGCAGGGAA CGTGCTCAGT CACTTTCAAT GGGCACCAGG 
AGAAAGGTTT TGGTTCTTGG ATCTGGCTAC ATATCTGAGC CTGTATTAGA ATATTTATCA 
AGAGATGGCA ATATAGAAAT AACAGTAGGA TCTGACATGA AGAATCAAAT TGAACAGTTA 
GGCAAGAAAT ATAATATTAA TCCTGTTAGC ATGGACATTT GTAAACAAGA AGAGAAGCTG 
GGCTTCTTGG TGGCAAAACA GGATCTTGTC ATCAGCTTGT TGCCTTATGT ATTGCACCCT 
CTTGTGGCCA AGGCCTGCAT CACAAACAAA GTTAACATGG TCACTGCAAG CTACATCACA 
CCAGCACTAA AAGAATTGGA AAAGAGTGTG GAAGATGCTG GCATCACAAT CATTGGTGAA 
TTGGGATTGG ACCCTGGTCT GGATCACATG TTAGCAATGG AAACAATAGA TAAAGCCAAG 
GAAGTGGGAG CCACGATTGA ATCATATATT TCCTACTGTG GTGGGCTTCC AGCCCCTGAA 
CATTCAAACA ATCCATTGAG ATATAAATTT AGCTGGAGTC CAGTGGGAGT TTTGATGAAT 
GTAATGCAGT CTGCCACCTA TCTGCTCGAT GGAAAGGTTG TGAATGTTGC AGGAGGCATC 
TCCTTTCTTG ATGCCGTTAC GTCCATGGAT TTTTTTCCAG GATTAAATTT GGAAGGCTAT 
CCTAACAGAG ACAGTACGAA ATATGCTGAG ATTTATGGCA TTTCTTCTGC TCACACTTTG 
TTGCGGGGGA CACTGAGATA TAAGGGATAT ATGAAAGCTT TGAATGGATT TGTAAAATTA 
GGTCTTATAA ACAGAGAAGC GCTTCCTGCC TTTAGACCTG AGGCCAACCC TCTCACCTGG 
AAACAACTCC TCTGTGACCT AGTTGGGATT TCACCCTCCT CTGAGCATGA TGTGTTGAAG 
GAAGCTGTTC TTAAGAAACT AGGAGGAGAC AATACCCAGT TGGAGGCTGC TGAATGGTTG 
GGCTTACTTG GGGATGAACA AGTTCCTCAG GCAGAGTCCA TTCTGGATGC CCTCTCCAAG 
CATTTGGTCA TGAAGCTTTC CTATGGTCCT GAAGAAAAAG ATATGATTGT GATGAGAGAC 
AGCTTTGGAA TCAGACATCC TTCTGGACAT TTAGAACATA AAACGATTGA TCTTGTGGCT 
TATGGGGACA TCAATGGCTT TTCAGCCATG GCTAAAACCG TGGGGTTACC CACCGCCATG 
GCAGCCAAAA TGTTGCTTGA TGGTGAAATT GGAGCCAAAG GCCTAATGGG GCCCTTTTCA 
AAGGAGATCT ATGGACCAAT ATTGGAGCGA ATTAAAGCAG AAGGCATTAT ATATACTACA 
CAGAGTACAA TTAAACCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_005754.2
CDS146..2926
Translation

Target ORF information:

RefSeq Version NM_005763.3
Organism Homo sapiens(human)
Definition Homo sapiens aminoadipate-semialdehyde synthase (AASS), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_005763.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
ATGCTGCAAG TACATAGGAC TGGACTGGGC AGGCTGGGGG TCAGCCTCTC CAAGGGTCTT 
CACCACAAAG CTGTGTTGGC CGTCCGGAGG GAGGATGTGA ACGCCTGGGA GAGAAGGGCC 
CCGCTAGCTC CCAAGCACAT CAAAGGCATC ACCAATCTGG GATACAAGGT CTTGATACAG 
CCTTCGAATC GGCGGGCCAT TCATGATAAG GACTATGTCA AAGCTGGTGG CATTCTTCAG 
GAGGATATTT CTGAAGCTTG TCTAATTTTA GGAGTTAAAA GACCTCCAGA GGAAAAATTA 
ATGTCCAGGA AGACTTATGC ATTTTTCTCC CACACAATAA AAGCTCAGGA GGCCAATATG 
GGCTTGTTGG ATGAGATTCT AAAACAGGAA ATTCGCCTTA TTGATTATGA GAAAATGGTG 
GATCATAGAG GAGTACGGGT AGTGGCATTT GGACAGTGGG CTGGTGTGGC AGGAATGATC 
AACATTTTAC ATGGAATGGG TTTAAGGCTC CTTGCTTTGG GACATCACAC ACCTTTTATG 
CACATTGGCA TGGCTCATAA CTACAGGAAT AGCAGTCAGG CTGTGCAAGC TGTCCGTGAT 
GCTGGCTATG AAATATCTTT GGGTTTGATG CCTAAGTCAA TAGGACCCTT AACATTTGTG 
TTCACAGGAA CTGGTAATGT TTCTAAGGGA GCCCAAGCAA TCTTTAATGA GCTACCTTGT 
GAATATGTGG AGCCCCATGA ATTAAAAGAA GTTTCCCAAA CTGGAGACCT CAGAAAAGTG 
TATGGGACGG TGTTAAGTCG TCATCATCAT CTTGTCAGGA AAACAGATGC TGTGTATGAT 
CCTGCAGAGT ATGACAAACA TCCGGAGCGC TACATAAGTC GTTTTAATAC TGATATTGCA 
CCCTATACAA CTTGCTTAAT TAATGGAATC TACTGGGAAC AAAACACTCC TCGCCTCCTA 
ACCCGCCAAG ATGCTCAGAG TCTCCTGGCT CCGGGCAAGT TCTCACCTGC TGGTGTGGAA 
GGCTGCCCTG CATTACCACA CAAACTCGTG GCAATATGTG ACATTTCAGC TGACACAGGA 
GGGTCTATAG AGTTTATGAC TGAGTGTACA ACAATAGAGC ATCCCTTTTG CATGTATGAT 
GCAGACCAGC ATATTATTCA TGACAGTGTT GAAGGCTCGG GGATCCTGAT GTGTTCCATT 
GACAATTTGC CGGCACAGCT CCCAATTGAA GCTACAGAAT GCTTTGGAGA CATGCTTTAC 
CCTTATGTTG AAGAAATGAT ATTATCAGAC GCGACACAGC CTCTTGAAAG TCAGAATTTT 
TCTCCTGTGG TGAGAGATGC AGTGATTACA TCCAACGGTA CATTACCTGA TAAATATAAA 
TATATCCAGA CACTCCGGGA GAGCAGGGAA CGTGCTCAGT CACTTTCAAT GGGCACCAGG 
AGAAAGGTTT TGGTTCTTGG ATCTGGCTAC ATATCTGAGC CTGTATTAGA ATATTTATCA 
AGAGATGGCA ATATAGAAAT AACAGTAGGA TCTGACATGA AGAATCAAAT TGAACAGTTA 
GGCAAGAAAT ATAATATTAA TCCTGTTAGC ATGGACATTT GTAAACAAGA AGAGAAGCTG 
GGCTTCTTGG TGGCAAAACA GGATCTTGTC ATCAGCTTGT TGCCTTATGT ATTGCACCCT 
CTTGTGGCCA AGGCCTGCAT CACAAACAAA GTTAACATGG TCACTGCAAG CTACATCACA 
CCAGCACTAA AAGAATTGGA AAAGAGTGTG GAAGATGCTG GCATCACAAT CATTGGTGAA 
TTGGGATTGG ACCCTGGTCT GGATCACATG TTAGCAATGG AAACAATAGA TAAAGCCAAG 
GAAGTGGGAG CCACGATTGA ATCATATATT TCCTACTGTG GTGGGCTTCC AGCCCCTGAA 
CATTCAAACA ATCCATTGAG ATATAAATTT AGCTGGAGTC CAGTGGGAGT TTTGATGAAT 
GTAATGCAGT CTGCCACCTA TCTGCTCGAT GGAAAGGTTG TGAATGTTGC AGGAGGCATC 
TCCTTTCTTG ATGCCGTTAC GTCCATGGAT TTTTTTCCAG GATTAAATTT GGAAGGCTAT 
CCTAACAGAG ACAGTACGAA ATATGCTGAG ATTTATGGCA TTTCTTCTGC TCACACTTTG 
TTGCGGGGGA CACTGAGATA TAAGGGATAT ATGAAAGCTT TGAATGGATT TGTAAAATTA 
GGTCTTATAA ACAGAGAAGC GCTTCCTGCC TTTAGACCTG AGGCCAACCC TCTCACCTGG 
AAACAACTCC TCTGTGACCT AGTTGGGATT TCACCCTCCT CTGAGCATGA TGTGTTGAAG 
GAAGCTGTTC TTAAGAAACT AGGAGGAGAC AATACCCAGT TGGAGGCTGC TGAATGGTTG 
GGCTTACTTG GGGATGAACA AGTTCCTCAG GCAGAGTCCA TTCTGGATGC CCTCTCCAAG 
CATTTGGTCA TGAAGCTTTC CTATGGTCCT GAAGAAAAAG ATATGATTGT GATGAGAGAC 
AGCTTTGGAA TCAGACATCC TTCTGGACAT TTAGAACATA AAACGATTGA TCTTGTGGCT 
TATGGGGACA TCAATGGCTT TTCAGCCATG GCTAAAACCG TGGGGTTACC CACCGCCATG 
GCAGCCAAAA TGTTGCTTGA TGGTGAAATT GGAGCCAAAG GCCTAATGGG GCCCTTTTCA 
AAGGAGATCT ATGGACCAAT ATTGGAGCGA ATTAAAGCAG AAGGCATTAT ATATACTACA 
CAGAGTACAA TTAAACCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17831
Clone ID Related Accession (Same CDS sequence) NM_005763.3 , NM_005763.4
Accession Version NM_005763.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2781bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-05-01
Organism Homo sapiens(human)
Product alpha-aminoadipic semialdehyde synthase, mitochondrial
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA995180.1, AF229180.1, AC006020.2 and BM669241.1. On Nov 22, 2018 this sequence version replaced NM_005763.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.21373.1, SRR1660809.102574.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000417368.7/ ENSP00000403768.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
ATGCTGCAAG TACATAGGAC TGGACTGGGC AGGCTGGGGG TCAGCCTCTC CAAGGGTCTT 
CACCACAAAG CTGTGTTGGC CGTCCGGAGG GAGGATGTGA ACGCCTGGGA GAGAAGGGCC 
CCGCTAGCTC CCAAGCACAT CAAAGGCATC ACCAATCTGG GATACAAGGT CTTGATACAG 
CCTTCGAATC GGCGGGCCAT TCATGATAAG GACTATGTCA AAGCTGGTGG CATTCTTCAG 
GAGGATATTT CTGAAGCTTG TCTAATTTTA GGAGTTAAAA GACCTCCAGA GGAAAAATTA 
ATGTCCAGGA AGACTTATGC ATTTTTCTCC CACACAATAA AAGCTCAGGA GGCCAATATG 
GGCTTGTTGG ATGAGATTCT AAAACAGGAA ATTCGCCTTA TTGATTATGA GAAAATGGTG 
GATCATAGAG GAGTACGGGT AGTGGCATTT GGACAGTGGG CTGGTGTGGC AGGAATGATC 
AACATTTTAC ATGGAATGGG TTTAAGGCTC CTTGCTTTGG GACATCACAC ACCTTTTATG 
CACATTGGCA TGGCTCATAA CTACAGGAAT AGCAGTCAGG CTGTGCAAGC TGTCCGTGAT 
GCTGGCTATG AAATATCTTT GGGTTTGATG CCTAAGTCAA TAGGACCCTT AACATTTGTG 
TTCACAGGAA CTGGTAATGT TTCTAAGGGA GCCCAAGCAA TCTTTAATGA GCTACCTTGT 
GAATATGTGG AGCCCCATGA ATTAAAAGAA GTTTCCCAAA CTGGAGACCT CAGAAAAGTG 
TATGGGACGG TGTTAAGTCG TCATCATCAT CTTGTCAGGA AAACAGATGC TGTGTATGAT 
CCTGCAGAGT ATGACAAACA TCCGGAGCGC TACATAAGTC GTTTTAATAC TGATATTGCA 
CCCTATACAA CTTGCTTAAT TAATGGAATC TACTGGGAAC AAAACACTCC TCGCCTCCTA 
ACCCGCCAAG ATGCTCAGAG TCTCCTGGCT CCGGGCAAGT TCTCACCTGC TGGTGTGGAA 
GGCTGCCCTG CATTACCACA CAAACTCGTG GCAATATGTG ACATTTCAGC TGACACAGGA 
GGGTCTATAG AGTTTATGAC TGAGTGTACA ACAATAGAGC ATCCCTTTTG CATGTATGAT 
GCAGACCAGC ATATTATTCA TGACAGTGTT GAAGGCTCGG GGATCCTGAT GTGTTCCATT 
GACAATTTGC CGGCACAGCT CCCAATTGAA GCTACAGAAT GCTTTGGAGA CATGCTTTAC 
CCTTATGTTG AAGAAATGAT ATTATCAGAC GCGACACAGC CTCTTGAAAG TCAGAATTTT 
TCTCCTGTGG TGAGAGATGC AGTGATTACA TCCAACGGTA CATTACCTGA TAAATATAAA 
TATATCCAGA CACTCCGGGA GAGCAGGGAA CGTGCTCAGT CACTTTCAAT GGGCACCAGG 
AGAAAGGTTT TGGTTCTTGG ATCTGGCTAC ATATCTGAGC CTGTATTAGA ATATTTATCA 
AGAGATGGCA ATATAGAAAT AACAGTAGGA TCTGACATGA AGAATCAAAT TGAACAGTTA 
GGCAAGAAAT ATAATATTAA TCCTGTTAGC ATGGACATTT GTAAACAAGA AGAGAAGCTG 
GGCTTCTTGG TGGCAAAACA GGATCTTGTC ATCAGCTTGT TGCCTTATGT ATTGCACCCT 
CTTGTGGCCA AGGCCTGCAT CACAAACAAA GTTAACATGG TCACTGCAAG CTACATCACA 
CCAGCACTAA AAGAATTGGA AAAGAGTGTG GAAGATGCTG GCATCACAAT CATTGGTGAA 
TTGGGATTGG ACCCTGGTCT GGATCACATG TTAGCAATGG AAACAATAGA TAAAGCCAAG 
GAAGTGGGAG CCACGATTGA ATCATATATT TCCTACTGTG GTGGGCTTCC AGCCCCTGAA 
CATTCAAACA ATCCATTGAG ATATAAATTT AGCTGGAGTC CAGTGGGAGT TTTGATGAAT 
GTAATGCAGT CTGCCACCTA TCTGCTCGAT GGAAAGGTTG TGAATGTTGC AGGAGGCATC 
TCCTTTCTTG ATGCCGTTAC GTCCATGGAT TTTTTTCCAG GATTAAATTT GGAAGGCTAT 
CCTAACAGAG ACAGTACGAA ATATGCTGAG ATTTATGGCA TTTCTTCTGC TCACACTTTG 
TTGCGGGGGA CACTGAGATA TAAGGGATAT ATGAAAGCTT TGAATGGATT TGTAAAATTA 
GGTCTTATAA ACAGAGAAGC GCTTCCTGCC TTTAGACCTG AGGCCAACCC TCTCACCTGG 
AAACAACTCC TCTGTGACCT AGTTGGGATT TCACCCTCCT CTGAGCATGA TGTGTTGAAG 
GAAGCTGTTC TTAAGAAACT AGGAGGAGAC AATACCCAGT TGGAGGCTGC TGAATGGTTG 
GGCTTACTTG GGGATGAACA AGTTCCTCAG GCAGAGTCCA TTCTGGATGC CCTCTCCAAG 
CATTTGGTCA TGAAGCTTTC CTATGGTCCT GAAGAAAAAG ATATGATTGT GATGAGAGAC 
AGCTTTGGAA TCAGACATCC TTCTGGACAT TTAGAACATA AAACGATTGA TCTTGTGGCT 
TATGGGGACA TCAATGGCTT TTCAGCCATG GCTAAAACCG TGGGGTTACC CACCGCCATG 
GCAGCCAAAA TGTTGCTTGA TGGTGAAATT GGAGCCAAAG GCCTAATGGG GCCCTTTTCA 
AAGGAGATCT ATGGACCAAT ATTGGAGCGA ATTAAAGCAG AAGGCATTAT ATATACTACA 
CAGAGTACAA TTAAACCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_005754.2
CDS105..2885
Translation

Target ORF information:

RefSeq Version NM_005763.4
Organism Homo sapiens(human)
Definition Homo sapiens aminoadipate-semialdehyde synthase (AASS), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_005763.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
ATGCTGCAAG TACATAGGAC TGGACTGGGC AGGCTGGGGG TCAGCCTCTC CAAGGGTCTT 
CACCACAAAG CTGTGTTGGC CGTCCGGAGG GAGGATGTGA ACGCCTGGGA GAGAAGGGCC 
CCGCTAGCTC CCAAGCACAT CAAAGGCATC ACCAATCTGG GATACAAGGT CTTGATACAG 
CCTTCGAATC GGCGGGCCAT TCATGATAAG GACTATGTCA AAGCTGGTGG CATTCTTCAG 
GAGGATATTT CTGAAGCTTG TCTAATTTTA GGAGTTAAAA GACCTCCAGA GGAAAAATTA 
ATGTCCAGGA AGACTTATGC ATTTTTCTCC CACACAATAA AAGCTCAGGA GGCCAATATG 
GGCTTGTTGG ATGAGATTCT AAAACAGGAA ATTCGCCTTA TTGATTATGA GAAAATGGTG 
GATCATAGAG GAGTACGGGT AGTGGCATTT GGACAGTGGG CTGGTGTGGC AGGAATGATC 
AACATTTTAC ATGGAATGGG TTTAAGGCTC CTTGCTTTGG GACATCACAC ACCTTTTATG 
CACATTGGCA TGGCTCATAA CTACAGGAAT AGCAGTCAGG CTGTGCAAGC TGTCCGTGAT 
GCTGGCTATG AAATATCTTT GGGTTTGATG CCTAAGTCAA TAGGACCCTT AACATTTGTG 
TTCACAGGAA CTGGTAATGT TTCTAAGGGA GCCCAAGCAA TCTTTAATGA GCTACCTTGT 
GAATATGTGG AGCCCCATGA ATTAAAAGAA GTTTCCCAAA CTGGAGACCT CAGAAAAGTG 
TATGGGACGG TGTTAAGTCG TCATCATCAT CTTGTCAGGA AAACAGATGC TGTGTATGAT 
CCTGCAGAGT ATGACAAACA TCCGGAGCGC TACATAAGTC GTTTTAATAC TGATATTGCA 
CCCTATACAA CTTGCTTAAT TAATGGAATC TACTGGGAAC AAAACACTCC TCGCCTCCTA 
ACCCGCCAAG ATGCTCAGAG TCTCCTGGCT CCGGGCAAGT TCTCACCTGC TGGTGTGGAA 
GGCTGCCCTG CATTACCACA CAAACTCGTG GCAATATGTG ACATTTCAGC TGACACAGGA 
GGGTCTATAG AGTTTATGAC TGAGTGTACA ACAATAGAGC ATCCCTTTTG CATGTATGAT 
GCAGACCAGC ATATTATTCA TGACAGTGTT GAAGGCTCGG GGATCCTGAT GTGTTCCATT 
GACAATTTGC CGGCACAGCT CCCAATTGAA GCTACAGAAT GCTTTGGAGA CATGCTTTAC 
CCTTATGTTG AAGAAATGAT ATTATCAGAC GCGACACAGC CTCTTGAAAG TCAGAATTTT 
TCTCCTGTGG TGAGAGATGC AGTGATTACA TCCAACGGTA CATTACCTGA TAAATATAAA 
TATATCCAGA CACTCCGGGA GAGCAGGGAA CGTGCTCAGT CACTTTCAAT GGGCACCAGG 
AGAAAGGTTT TGGTTCTTGG ATCTGGCTAC ATATCTGAGC CTGTATTAGA ATATTTATCA 
AGAGATGGCA ATATAGAAAT AACAGTAGGA TCTGACATGA AGAATCAAAT TGAACAGTTA 
GGCAAGAAAT ATAATATTAA TCCTGTTAGC ATGGACATTT GTAAACAAGA AGAGAAGCTG 
GGCTTCTTGG TGGCAAAACA GGATCTTGTC ATCAGCTTGT TGCCTTATGT ATTGCACCCT 
CTTGTGGCCA AGGCCTGCAT CACAAACAAA GTTAACATGG TCACTGCAAG CTACATCACA 
CCAGCACTAA AAGAATTGGA AAAGAGTGTG GAAGATGCTG GCATCACAAT CATTGGTGAA 
TTGGGATTGG ACCCTGGTCT GGATCACATG TTAGCAATGG AAACAATAGA TAAAGCCAAG 
GAAGTGGGAG CCACGATTGA ATCATATATT TCCTACTGTG GTGGGCTTCC AGCCCCTGAA 
CATTCAAACA ATCCATTGAG ATATAAATTT AGCTGGAGTC CAGTGGGAGT TTTGATGAAT 
GTAATGCAGT CTGCCACCTA TCTGCTCGAT GGAAAGGTTG TGAATGTTGC AGGAGGCATC 
TCCTTTCTTG ATGCCGTTAC GTCCATGGAT TTTTTTCCAG GATTAAATTT GGAAGGCTAT 
CCTAACAGAG ACAGTACGAA ATATGCTGAG ATTTATGGCA TTTCTTCTGC TCACACTTTG 
TTGCGGGGGA CACTGAGATA TAAGGGATAT ATGAAAGCTT TGAATGGATT TGTAAAATTA 
GGTCTTATAA ACAGAGAAGC GCTTCCTGCC TTTAGACCTG AGGCCAACCC TCTCACCTGG 
AAACAACTCC TCTGTGACCT AGTTGGGATT TCACCCTCCT CTGAGCATGA TGTGTTGAAG 
GAAGCTGTTC TTAAGAAACT AGGAGGAGAC AATACCCAGT TGGAGGCTGC TGAATGGTTG 
GGCTTACTTG GGGATGAACA AGTTCCTCAG GCAGAGTCCA TTCTGGATGC CCTCTCCAAG 
CATTTGGTCA TGAAGCTTTC CTATGGTCCT GAAGAAAAAG ATATGATTGT GATGAGAGAC 
AGCTTTGGAA TCAGACATCC TTCTGGACAT TTAGAACATA AAACGATTGA TCTTGTGGCT 
TATGGGGACA TCAATGGCTT TTCAGCCATG GCTAAAACCG TGGGGTTACC CACCGCCATG 
GCAGCCAAAA TGTTGCTTGA TGGTGAAATT GGAGCCAAAG GCCTAATGGG GCCCTTTTCA 
AAGGAGATCT ATGGACCAAT ATTGGAGCGA ATTAAAGCAG AAGGCATTAT ATATACTACA 
CAGAGTACAA TTAAACCATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu63737
Clone ID Related Accession (Same CDS sequence) XM_011515725.2
Accession Version XM_011515725.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2685bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-12
Organism Homo sapiens(human)
Product alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515725.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGCTGCAAG TACATAGGAC TGGACTGGGC AGGCTGGGGG TCAGCCTCTC CAAGGGTCTT 
CACCACAAAG CTGTGTTGGC CGTCCGGAGG GAGGATGTGA ACGCCTGGGA GAGAAGGGCC 
CCGCTAGCTC CCAAGCACAT CAAAGGCATC ACCAATCTGG GATACAAGGT CTTGATACAG 
CCTTCGAATC GGCGGGCCAT TCATGATAAG GACTATGTCA AAGCTGGTGG CATTCTTCAG 
GAGGATATTT CTGAAGCTTG TCTAATTTTA GGAGTTAAAA GACCTCCAGA GGAAAAATTA 
ATGTCCAGGA AGACTTATGC ATTTTTCTCC CACACAATAA AAGCTCAGGA GGCCAATATG 
GGCTTGTTGG ATGAGATTCT AAAACAGGAA ATTCGCCTTA TTGATTATGA GAAAATGGTG 
GATCATAGAG GAGTACGGGT AGTGGCATTT GGACAGTGGG CTGGTGTGGC AGGAATGATC 
AACATTTTAC ATGGAATGGG TTTAAGGCTC CTTGCTTTGG GACATCACAC ACCTTTTATG 
CACATTGGCA TGGCTCATAA CTACAGGAAT AGCAGTCAGG CTGTGCAAGC TGTCCGTGAT 
GCTGGCTATG AAATATCTTT GGGTTTGATG CCTAAGTCAA TAGGACCCTT AACATTTGTG 
TTCACAGGAA CTGGTAATGT TTCTAAGGGA GCCCAAGCAA TCTTTAATGA GCTACCTTGT 
GAATATGTGG AGCCCCATGA ATTAAAAGAA GTTTCCCAAA CTGGAGACCT CAGAAAAGTG 
TATGGGACGG TGTTAAGTCG TCATCATCAT CTTGTCAGGA AAACAGATGC TGTGTATGAT 
CCTGCAGAGT ATGACAAACA TCCGGAGCGC TACATAAGTC GTTTTAATAC TGATATTGCA 
CCCTATACAA CTTGCTTAAT TAATGGAATC TACTGGGAAC AAAACACTCC TCGCCTCCTA 
ACCCGCCAAG ATGCTCAGAG TCTCCTGGCT CCGGGCAAGT TCTCACCTGC TGGTGTGGAA 
GGCTGCCCTG CATTACCACA CAAACTCGTG GCAATATGTG ACATTTCAGC TGACACAGGA 
GGGTCTATAG AGTTTATGAC TGAGTGTACA ACAATAGAGC ATCCCTTTTG CATGTATGAT 
GCAGACCAGC ATATTATTCA TGACAGTGTT GAAGGCTCGG GGATCCTGAT GTGTTCCATT 
GACAATTTGC CGGCACAGCT CCCAATTGAA GCTACAGAAT GCTTTGGAGA CATGCTTTAC 
CCTTATGTTG AAGAAATGAT ATTATCAGAC GCGACACAGC CTCTTGAAAG TCAGAATTTT 
TCTCCTGTGG TGAGAGATGC AGTGATTACA TCCAACGGTA CATTACCTGA TAAATATAAA 
TATATCCAGA CACTCCGGGA GAGCAGGGAA CGTGCTCAGT CACTTTCAAT GGGCACCAGG 
AGAAAGGTTT TGGTTCTTGG ATCTGGCTAC ATATCTGAGC CTGTATTAGA ATATTTATCA 
AGAGATGGCA ATATAGAAAT AACAGTAGGA TCTGACATGA AGAATCAAAT TGAACAGTTA 
GGCAAGAAAT ATAATATTAA TCCTGTTAGC ATGGACATTT GTAAACAAGA AGAGAAGCTG 
GGCTTCTTGG TGGCAAAACA GGATCTTGTC ATCAGCTTGT TGCCTTATGT ATTGCACCCT 
CTTGTGGCCA AGGCCTGCAT CACAAACAAA GTTAACATGG TCACTGCAAG CTACATCACA 
CCAGCACTAA AAGAATTGGA AAAGAGTGTG GAAGATGCTG GCATCACAAT CATTGGTGAA 
TTGGGATTGG ACCCTGGTCT GGATCACATG TTAGCAATGG AAACAATAGA TAAAGCCAAG 
GAAGTGGGAG CCACGATTGA ATCATATATT TCCTACTGTG GTGGGCTTCC AGCCCCTGAA 
CATTCAAACA ATCCATTGAG ATATAAATTT AGCTGGAGTC CAGTGGGAGT TTTGATGAAT 
GTAATGCAGT CTGCCACCTA TCTGCTCGAT GGAAAGGTTG TGAATGTTGC AGGAGGCATC 
TCCTTTCTTG ATGCCGTTAC GTCCATGGAT TTTTTTCCAG GATTAAATTT GGAAGGCTAT 
CCTAACAGAG ACAGTACGAA ATATGCTGAG ATTTATGGCA TTTCTTCTGC TCACACTTTG 
TTGCGGGGGA CACTGAGATA TAAGAAACAA CTCCTCTGTG ACCTAGTTGG GATTTCACCC 
TCCTCTGAGC ATGATGTGTT GAAGGAAGCT GTTCTTAAGA AACTAGGAGG AGACAATACC 
CAGTTGGAGG CTGCTGAATG GTTGGGCTTA CTTGGGGATG AACAAGTTCC TCAGGCAGAG 
TCCATTCTGG ATGCCCTCTC CAAGCATTTG GTCATGAAGC TTTCCTATGG TCCTGAAGAA 
AAAGATATGA TTGTGATGAG AGACAGCTTT GGAATCAGAC ATCCTTCTGG ACATTTAGAA 
CATAAAACGA TTGATCTTGT GGCTTATGGG GACATCAATG GCTTTTCAGC CATGGCTAAA 
ACCGTGGGGT TACCCACCGC CATGGCAGCC AAAATGTTGC TTGATGGTGA AATTGGAGCC 
AAAGGCCTAA TGGGGCCCTT TTCAAAGGAG ATCTATGGAC CAATATTGGA GCGAATTAAA 
GCAGAAGGCA TTATATATAC TACACAGAGT ACAATTAAAC CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011514027.1
CDS125..2809
Translation

Target ORF information:

RefSeq Version XM_011515725.2
Organism Homo sapiens(human)
Definition Homo sapiens aminoadipate-semialdehyde synthase (AASS), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011515725.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGCTGCAAG TACATAGGAC TGGACTGGGC AGGCTGGGGG TCAGCCTCTC CAAGGGTCTT 
CACCACAAAG CTGTGTTGGC CGTCCGGAGG GAGGATGTGA ACGCCTGGGA GAGAAGGGCC 
CCGCTAGCTC CCAAGCACAT CAAAGGCATC ACCAATCTGG GATACAAGGT CTTGATACAG 
CCTTCGAATC GGCGGGCCAT TCATGATAAG GACTATGTCA AAGCTGGTGG CATTCTTCAG 
GAGGATATTT CTGAAGCTTG TCTAATTTTA GGAGTTAAAA GACCTCCAGA GGAAAAATTA 
ATGTCCAGGA AGACTTATGC ATTTTTCTCC CACACAATAA AAGCTCAGGA GGCCAATATG 
GGCTTGTTGG ATGAGATTCT AAAACAGGAA ATTCGCCTTA TTGATTATGA GAAAATGGTG 
GATCATAGAG GAGTACGGGT AGTGGCATTT GGACAGTGGG CTGGTGTGGC AGGAATGATC 
AACATTTTAC ATGGAATGGG TTTAAGGCTC CTTGCTTTGG GACATCACAC ACCTTTTATG 
CACATTGGCA TGGCTCATAA CTACAGGAAT AGCAGTCAGG CTGTGCAAGC TGTCCGTGAT 
GCTGGCTATG AAATATCTTT GGGTTTGATG CCTAAGTCAA TAGGACCCTT AACATTTGTG 
TTCACAGGAA CTGGTAATGT TTCTAAGGGA GCCCAAGCAA TCTTTAATGA GCTACCTTGT 
GAATATGTGG AGCCCCATGA ATTAAAAGAA GTTTCCCAAA CTGGAGACCT CAGAAAAGTG 
TATGGGACGG TGTTAAGTCG TCATCATCAT CTTGTCAGGA AAACAGATGC TGTGTATGAT 
CCTGCAGAGT ATGACAAACA TCCGGAGCGC TACATAAGTC GTTTTAATAC TGATATTGCA 
CCCTATACAA CTTGCTTAAT TAATGGAATC TACTGGGAAC AAAACACTCC TCGCCTCCTA 
ACCCGCCAAG ATGCTCAGAG TCTCCTGGCT CCGGGCAAGT TCTCACCTGC TGGTGTGGAA 
GGCTGCCCTG CATTACCACA CAAACTCGTG GCAATATGTG ACATTTCAGC TGACACAGGA 
GGGTCTATAG AGTTTATGAC TGAGTGTACA ACAATAGAGC ATCCCTTTTG CATGTATGAT 
GCAGACCAGC ATATTATTCA TGACAGTGTT GAAGGCTCGG GGATCCTGAT GTGTTCCATT 
GACAATTTGC CGGCACAGCT CCCAATTGAA GCTACAGAAT GCTTTGGAGA CATGCTTTAC 
CCTTATGTTG AAGAAATGAT ATTATCAGAC GCGACACAGC CTCTTGAAAG TCAGAATTTT 
TCTCCTGTGG TGAGAGATGC AGTGATTACA TCCAACGGTA CATTACCTGA TAAATATAAA 
TATATCCAGA CACTCCGGGA GAGCAGGGAA CGTGCTCAGT CACTTTCAAT GGGCACCAGG 
AGAAAGGTTT TGGTTCTTGG ATCTGGCTAC ATATCTGAGC CTGTATTAGA ATATTTATCA 
AGAGATGGCA ATATAGAAAT AACAGTAGGA TCTGACATGA AGAATCAAAT TGAACAGTTA 
GGCAAGAAAT ATAATATTAA TCCTGTTAGC ATGGACATTT GTAAACAAGA AGAGAAGCTG 
GGCTTCTTGG TGGCAAAACA GGATCTTGTC ATCAGCTTGT TGCCTTATGT ATTGCACCCT 
CTTGTGGCCA AGGCCTGCAT CACAAACAAA GTTAACATGG TCACTGCAAG CTACATCACA 
CCAGCACTAA AAGAATTGGA AAAGAGTGTG GAAGATGCTG GCATCACAAT CATTGGTGAA 
TTGGGATTGG ACCCTGGTCT GGATCACATG TTAGCAATGG AAACAATAGA TAAAGCCAAG 
GAAGTGGGAG CCACGATTGA ATCATATATT TCCTACTGTG GTGGGCTTCC AGCCCCTGAA 
CATTCAAACA ATCCATTGAG ATATAAATTT AGCTGGAGTC CAGTGGGAGT TTTGATGAAT 
GTAATGCAGT CTGCCACCTA TCTGCTCGAT GGAAAGGTTG TGAATGTTGC AGGAGGCATC 
TCCTTTCTTG ATGCCGTTAC GTCCATGGAT TTTTTTCCAG GATTAAATTT GGAAGGCTAT 
CCTAACAGAG ACAGTACGAA ATATGCTGAG ATTTATGGCA TTTCTTCTGC TCACACTTTG 
TTGCGGGGGA CACTGAGATA TAAGAAACAA CTCCTCTGTG ACCTAGTTGG GATTTCACCC 
TCCTCTGAGC ATGATGTGTT GAAGGAAGCT GTTCTTAAGA AACTAGGAGG AGACAATACC 
CAGTTGGAGG CTGCTGAATG GTTGGGCTTA CTTGGGGATG AACAAGTTCC TCAGGCAGAG 
TCCATTCTGG ATGCCCTCTC CAAGCATTTG GTCATGAAGC TTTCCTATGG TCCTGAAGAA 
AAAGATATGA TTGTGATGAG AGACAGCTTT GGAATCAGAC ATCCTTCTGG ACATTTAGAA 
CATAAAACGA TTGATCTTGT GGCTTATGGG GACATCAATG GCTTTTCAGC CATGGCTAAA 
ACCGTGGGGT TACCCACCGC CATGGCAGCC AAAATGTTGC TTGATGGTGA AATTGGAGCC 
AAAGGCCTAA TGGGGCCCTT TTCAAAGGAG ATCTATGGAC CAATATTGGA GCGAATTAAA 
GCAGAAGGCA TTATATATAC TACACAGAGT ACAATTAAAC CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops.
The Journal of biological chemistry290(32)19756-69(2015 Aug)
Sasse SK,Zuo Z,Kadiyala V,Zhang L,Pufall MA,Jain MK,Phang TL,Stormo GD,Gerber AN


book

Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia.
Human molecular genetics23(18)5009-16(2014 Sep)
Houten SM,Denis S,Te Brinke H,Jongejan A,van Kampen AH,Bradley EJ,Baas F,Hennekam RC,Millington DS,Young SP,Frazier DM,Gucsavas-Calikoglu M,Wanders RJ


book

Genetic basis of hyperlysinemia.
Orphanet journal of rare diseases857(2013 Apr)
Houten SM,Te Brinke H,Denis S,Ruiter JP,Knegt AC,de Klerk JB,Augoustides-Savvopoulou P,H?berle J,Baumgartner MR,Co?kun T,Zschocke J,Sass JO,Poll-The BT,Wanders RJ,Duran M


book

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ


book

Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia.
American journal of human genetics66(6)1736-43(2000 Jun)
Sacksteder KA,Biery BJ,Morrell JC,Goodman BK,Geisbrecht BV,Cox RP,Gould SJ,Geraghty MT