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AEBP1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol AEBP1
Entrez Gene ID 165
Full Name AE binding protein 1
Synonyms ACLP
General protein information
Preferred Names

AE binding protein 1

Names

adipocyte enhancer-binding protein 1
aortic carboxypeptidase-like protein

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

7

7p13

Summary This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013].
Disorder MIM:

602981


mRNA and Protein(s)

mRNA Protein Name
XM_011515162.1 XP_011513464.1 adipocyte enhancer-binding protein 1 isoform X1
NM_001129.4 NP_001120.3 adipocyte enhancer-binding protein 1 precursor



Xenopus tropicalis (tropical clawed frog) aebp1 XP_002932623.2
Pan troglodytes (chimpanzee) AEBP1 XP_003318438.1
Bos taurus (cattle) AEBP1 NP_777264.2
Canis lupus familiaris (dog) AEBP1 XP_005642251.1
Mus musculus (house mouse) Aebp1 NP_033766.2
Rattus norvegicus (Norway rat) Aebp1 NP_001094440.1
Homo sapiens (human) AEBP1 NP_001120.3


Related articles in PubMed

Aortic carboxypeptidase-like protein (ACLP) enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways.
Tumelty KE, Smith BD, Nugent MA, Layne MD
The Journal of biological chemistry289(5)2526-36(2014 Jan)

Berberine-induced inhibition of adipocyte enhancer-binding protein 1 attenuates oxidized low-density lipoprotein accumulation and foam cell formation in phorbol 12-myristate 13-acetate-induced macrophages.
Huang Z, Dong F, Li S, Chu M, Zhou H, Lu Z, Huang W
European journal of pharmacology690(1-3)164-9(2012 Sep)

AEBP1 gene variants in infants with gastroschisis.
Feldkamp ML, Bowles NE, Botto LD
Birth defects research. Part A, Clinical and molecular teratology94(9)738-42(2012 Sep)

Identification of genomic targets of transcription factor AEBP1 and its role in survival of glioma cells.
Ladha J, Sinha S, Bhat V, Donakonda S, Rao SM
Molecular cancer research : MCR10(8)1039-51(2012 Aug)

Proteomics characterization of extracellular space components in the human aorta.
Didangelos A, Yin X, Mandal K, Baumert M, Jahangiri M, Mayr M
Molecular & cellular proteomics : MCP9(9)2048-62(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ACLP stimulates the fibroblast-to-myofibroblast transition by promoting SMA expression via TGFbeta signaling and promoting collagen expression through a TGFbeta receptor-independent pathway.
Title: Aortic carboxypeptidase-like protein (ACLP) enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways.

There is no statistically significant differences in the frequency of variants in AEBP1 among the gastroschisis case group compared to a Caucasian control group.
Title: AEBP1 gene variants in infants with gastroschisis.

Both cellular proliferation and survival were affected in AEBP1-silenced U87MG and U138MG cell lines and a significant percentage of these cells were directed towards apoptosis.
Title: Identification of genomic targets of transcription factor AEBP1 and its role in survival of glioma cells.

This review focuses on the recently reported regulatory functions that adipocyte enhancer-binding protein 1 (AEBP1) exerts on PPARgamma1 and LXRalpha transcriptional activity in the context of macrophage cholesterol homeostasis and inflammation.
Title: PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1.

ACLP and its discoidin-like domain may be novel targets for anti-myofibroblast-based therapies for the treatment of pulmonary fibrosis.
Title: Aortic carboxypeptidase-like protein is expressed in fibrotic human lung and its absence protects against bleomycin-induced lung fibrosis.

The following AEBP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AEBP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu15686 NM_001129.4
Latest version!
Homo sapiens AE binding protein 1 (AEBP1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $559.30
$799.00
OHu56213 XM_011515162.1
Latest version!
Homo sapiens AE binding protein 1 (AEBP1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $559.30
$799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu15686
Clone ID Related Accession (Same CDS sequence) NM_001129.4
Accession Version NM_001129.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3477bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-09-10
Organism Homo sapiens(Human)
Product adipocyte enhancer-binding protein 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC038588.1, DB213495.1 and BM672693.1. On May 10, 2013 this sequence version replaced NM_001129.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC038588.1, AB209744.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCGGCCG TGCGCGGGGC GCCCCTGCTC AGCTGCCTCC TGGCGTTGCT GGCCCTGTGC 
CCTGGAGGGC GCCCGCAGAC GGTGCTGACC GACGACGAGA TCGAGGAGTT CCTCGAGGGC
TTCCTGTCAG AGCTAGAACC TGAGCCCCGG GAGGACGACG TGGAGGCCCC GCCGCCTCCC
GAGCCCACCC CGCGGGTCCG AAAAGCCCAG GCGGGGGGCA AGCCAGGGAA GCGGCCAGGG
ACGGCCGCAG AAGTGCCTCC GGAAAAGACC AAAGACAAAG GGAAGAAAGG CAAGAAAGAC
AAAGGCCCCA AGGTGCCCAA GGAGTCCTTG GAGGGGTCCC CCAGGCCGCC CAAGAAGGGG
AAGGAGAAGC CACCCAAGGC CACCAAGAAG CCCAAGGAGA AGCCACCTAA GGCCACCAAG
AAGCCCAAGG AGAAGCCACC CAAGGCCACC AAGAAGCCCA AAGAGAAGCC ACCCAAGGCC
ACCAAGAAGC CCCCGTCAGG GAAGAGGCCC CCCATTCTGG CTCCCTCAGA AACCCTGGAG
TGGCCACTGC CCCCACCCCC CAGCCCTGGC CCCGAGGAGC TACCCCAGGA GGGAGGGGCG
CCCCTCTCAA ATAACTGGCA GAATCCAGGA GAGGAGACCC ATGTGGAGGC ACGGGAGCAC
CAGCCTGAGC CGGAGGAGGA GACCGAGCAA CCCACACTGG ACTACAATGA CCAGATCGAG
AGGGAGGACT ATGAGGACTT TGAGTACATT CGGCGCCAGA AGCAACCCAG GCCACCCCCA
AGCAGAAGGA GGAGGCCCGA GCGGGTCTGG CCAGAGCCCC CTGAGGAGAA GGCCCCGGCC
CCAGCCCCGG AGGAGAGGAT TGAGCCTCCT GTGAAGCCTC TGCTGCCCCC GCTGCCCCCT
GACTATGGTG ATGGTTACGT GATCCCCAAC TACGATGACA TGGACTATTA CTTTGGGCCT
CCTCCGCCCC AGAAGCCCGA TGCTGAGCGC CAGACAGACG AAGAGAAGGA GGAGCTGAAG
AAACCCAAAA AGGAGGACAG CAGCCCCAAG GAGGAGACCG ACAAGTGGGC AGTGGAGAAG
GGCAAGGACC ACAAAGAGCC CCGAAAGGGC GAGGAGTTGG AGGAGGAGTG GACGCCTACG
GAGAAAGTCA AGTGTCCCCC CATTGGGATG GAGTCACACC GTATTGAGGA CAACCAGATC
CGAGCCTCCT CCATGCTGCG CCACGGCCTG GGGGCACAGC GCGGCCGGCT CAACATGCAG
ACCGGTGCCA CTGAGGACGA CTACTATGAT GGTGCGTGGT GTGCCGAGGA CGATGCCAGG
ACCCAGTGGA TAGAGGTGGA CACCAGGAGG ACTACCCGGT TCACAGGCGT CATCACCCAG
GGCAGAGACT CCAGCATCCA TGACGATTTT GTGACCACCT TCTTCGTGGG CTTCAGCAAT
GACAGCCAGA CATGGGTGAT GTACACCAAC GGCTATGAGG AAATGACCTT TCATGGGAAC
GTGGACAAGG ACACACCCGT GCTGAGTGAG CTCCCAGAGC CGGTGGTGGC TCGTTTCATC
CGCATCTACC CACTCACCTG GAATGGCAGC CTGTGCATGC GCCTGGAGGT GCTGGGGTGC
TCTGTGGCCC CTGTCTACAG CTACTACGCA CAGAATGAGG TGGTGGCCAC CGATGACCTG
GATTTCCGGC ACCACAGCTA CAAGGACATG CGCCAGCTCA TGAAGGTGGT GAACGAGGAG
TGCCCCACCA TCACCCGCAC TTACAGCCTG GGCAAGAGCT CACGAGGCCT CAAGATCTAT
GCCATGGAGA TCTCAGACAA CCCTGGGGAG CATGAACTGG GGGAGCCCGA GTTCCGCTAC
ACTGCTGGGA TCCATGGCAA CGAGGTGCTG GGCCGAGAGC TGTTGCTGCT GCTCATGCAG
TACCTGTGCC GAGAGTACCG CGATGGGAAC CCACGTGTGC GCAGCCTGGT GCAGGACACA
CGCATCCACC TGGTGCCCTC ACTGAACCCT GATGGCTACG AGGTGGCAGC GCAGATGGGC
TCAGAGTTTG GGAACTGGGC GCTGGGACTG TGGACTGAGG AGGGCTTTGA CATCTTTGAA
GATTTCCCGG ATCTCAACTC TGTGCTCTGG GGAGCTGAGG AGAGGAAATG GGTCCCCTAC
CGGGTCCCCA ACAATAACTT GCCCATCCCT GAACGCTACC TTTCGCCAGA TGCCACGGTA
TCCACGGAGG TCCGGGCCAT CATTGCCTGG ATGGAGAAGA ACCCCTTCGT GCTGGGAGCA
AATCTGAACG GCGGCGAGCG GCTAGTATCC TACCCCTACG ATATGGCCCG CACGCCTACC
CAGGAGCAGC TGCTGGCCGC AGCCATGGCA GCAGCCCGGG GGGAGGATGA GGACGAGGTC
TCCGAGGCCC AGGAGACTCC AGACCACGCC ATCTTCCGGT GGCTTGCCAT CTCCTTCGCC
TCCGCACACC TCACCTTGAC CGAGCCCTAC CGCGGAGGCT GCCAAGCCCA GGACTACACC
GGCGGCATGG GCATCGTCAA CGGGGCCAAG TGGAACCCCC GGACCGGGAC TATCAATGAC
TTCAGTTACC TGCATACCAA CTGCCTGGAG CTCTCCTTCT ACCTGGGCTG TGACAAGTTC
CCTCATGAGA GTGAGCTGCC CCGCGAGTGG GAGAACAACA AGGAGGCGCT GCTCACCTTC
ATGGAGCAGG TGCACCGCGG CATTAAGGGG GTGGTGACGG ACGAGCAAGG CATCCCCATT
GCCAACGCCA CCATCTCTGT GAGTGGCATT AATCACGGCG TGAAGACAGC CAGTGGTGGT
GATTACTGGC GAATCTTGAA CCCGGGTGAG TACCGCGTGA CAGCCCACGC GGAGGGCTAC
ACCCCGAGCG CCAAGACCTG CAATGTTGAC TATGACATCG GGGCCACTCA GTGCAACTTC
ATCCTGGCTC GCTCCAACTG GAAGCGCATC CGGGAGATCA TGGCCATGAA CGGGAACCGG
CCTATCCCAC ACATAGACCC ATCGCGCCCT ATGACCCCCC AACAGCGACG CCTGCAGCAG
CGACGCCTAC AACACCGCCT GCGGCTTCGG GCACAGATGC GGCTGCGGCG CCTCAACGCC
ACCACCACCC TAGGCCCCCA CACTGTGCCT CCCACGCTGC CCCCTGCCCC TGCCACCACC
CTGAGCACTA CCATAGAGCC CTGGGGCCTC ATACCGCCAA CCACCGCTGG CTGGGAGGAG
TCGGAGACTG AGACCTACAC AGAGGTGGTG ACAGAGTTTG GGACCGAGGT GGAGCCCGAG
TTTGGGACCA AGGTGGAGCC CGAGTTTGAG ACCCAGTTGG AGCCTGAGTT TGAGACCCAG
CTGGAACCCG AGTTTGAGGA AGAGGAGGAG GAGGAGAAAG AGGAGGAGAT AGCCACTGGC
CAGGCATTCC CCTTCACAAC AGTAGAGACC TACACAGTGA ACTTTGGGGA CTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001120.3
CDS306..3782
Misc Feature(1)261..263
Misc Feature(2)1455..1925
Misc Feature(3)1461..1922
Misc Feature(4)1473..1970
Misc Feature(5)1566..2177
Misc Feature(6)order(1605..1607,1689..1691,1710..1712)
Misc Feature(7)1968..3260
Misc Feature(8)1983..3014
Misc Feature(9)order(2178..2180,2187..2189,2373..2375,2400..2405,2592..2597,2613..2615,2625..2627,2847..2849,2859..2861,2865..2867,2925..2927)
Misc Feature(10)order(2178..2180,2187..2189,2592..2594)
Misc Feature(11)3024..3251
Misc Feature(12)3126..3779
Misc Feature(13)3321..3779
Exon (1)1..558
Exon (2)559..900
Exon (3)901..972
Exon (4)973..1044
Exon (5)1045..1167
Exon (6)1168..1245
Exon (7)1246..1323
Exon (8)1324..1401
Exon (9)1402..1455
Exon (10)1456..1565
Exon (11)1566..1705
Exon (12)1706..1790
Exon (13)1791..1935
Exon (14)1936..2021
Exon (15)2022..2145
Exon (16)2146..2342
Exon (17)2343..2522
Exon (18)2523..2874
Exon (19)2875..3014
Exon (20)3015..3114
Exon (21)3115..4086
Translation

Target ORF information:

RefSeq Version NM_001129.4
Organism Homo sapiens(Human)
Definition Homo sapiens AE binding protein 1 (AEBP1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001129.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCGGCCG TGCGCGGGGC GCCCCTGCTC AGCTGCCTCC TGGCGTTGCT GGCCCTGTGC 
CCTGGAGGGC GCCCGCAGAC GGTGCTGACC GACGACGAGA TCGAGGAGTT CCTCGAGGGC
TTCCTGTCAG AGCTAGAACC TGAGCCCCGG GAGGACGACG TGGAGGCCCC GCCGCCTCCC
GAGCCCACCC CGCGGGTCCG AAAAGCCCAG GCGGGGGGCA AGCCAGGGAA GCGGCCAGGG
ACGGCCGCAG AAGTGCCTCC GGAAAAGACC AAAGACAAAG GGAAGAAAGG CAAGAAAGAC
AAAGGCCCCA AGGTGCCCAA GGAGTCCTTG GAGGGGTCCC CCAGGCCGCC CAAGAAGGGG
AAGGAGAAGC CACCCAAGGC CACCAAGAAG CCCAAGGAGA AGCCACCTAA GGCCACCAAG
AAGCCCAAGG AGAAGCCACC CAAGGCCACC AAGAAGCCCA AAGAGAAGCC ACCCAAGGCC
ACCAAGAAGC CCCCGTCAGG GAAGAGGCCC CCCATTCTGG CTCCCTCAGA AACCCTGGAG
TGGCCACTGC CCCCACCCCC CAGCCCTGGC CCCGAGGAGC TACCCCAGGA GGGAGGGGCG
CCCCTCTCAA ATAACTGGCA GAATCCAGGA GAGGAGACCC ATGTGGAGGC ACGGGAGCAC
CAGCCTGAGC CGGAGGAGGA GACCGAGCAA CCCACACTGG ACTACAATGA CCAGATCGAG
AGGGAGGACT ATGAGGACTT TGAGTACATT CGGCGCCAGA AGCAACCCAG GCCACCCCCA
AGCAGAAGGA GGAGGCCCGA GCGGGTCTGG CCAGAGCCCC CTGAGGAGAA GGCCCCGGCC
CCAGCCCCGG AGGAGAGGAT TGAGCCTCCT GTGAAGCCTC TGCTGCCCCC GCTGCCCCCT
GACTATGGTG ATGGTTACGT GATCCCCAAC TACGATGACA TGGACTATTA CTTTGGGCCT
CCTCCGCCCC AGAAGCCCGA TGCTGAGCGC CAGACAGACG AAGAGAAGGA GGAGCTGAAG
AAACCCAAAA AGGAGGACAG CAGCCCCAAG GAGGAGACCG ACAAGTGGGC AGTGGAGAAG
GGCAAGGACC ACAAAGAGCC CCGAAAGGGC GAGGAGTTGG AGGAGGAGTG GACGCCTACG
GAGAAAGTCA AGTGTCCCCC CATTGGGATG GAGTCACACC GTATTGAGGA CAACCAGATC
CGAGCCTCCT CCATGCTGCG CCACGGCCTG GGGGCACAGC GCGGCCGGCT CAACATGCAG
ACCGGTGCCA CTGAGGACGA CTACTATGAT GGTGCGTGGT GTGCCGAGGA CGATGCCAGG
ACCCAGTGGA TAGAGGTGGA CACCAGGAGG ACTACCCGGT TCACAGGCGT CATCACCCAG
GGCAGAGACT CCAGCATCCA TGACGATTTT GTGACCACCT TCTTCGTGGG CTTCAGCAAT
GACAGCCAGA CATGGGTGAT GTACACCAAC GGCTATGAGG AAATGACCTT TCATGGGAAC
GTGGACAAGG ACACACCCGT GCTGAGTGAG CTCCCAGAGC CGGTGGTGGC TCGTTTCATC
CGCATCTACC CACTCACCTG GAATGGCAGC CTGTGCATGC GCCTGGAGGT GCTGGGGTGC
TCTGTGGCCC CTGTCTACAG CTACTACGCA CAGAATGAGG TGGTGGCCAC CGATGACCTG
GATTTCCGGC ACCACAGCTA CAAGGACATG CGCCAGCTCA TGAAGGTGGT GAACGAGGAG
TGCCCCACCA TCACCCGCAC TTACAGCCTG GGCAAGAGCT CACGAGGCCT CAAGATCTAT
GCCATGGAGA TCTCAGACAA CCCTGGGGAG CATGAACTGG GGGAGCCCGA GTTCCGCTAC
ACTGCTGGGA TCCATGGCAA CGAGGTGCTG GGCCGAGAGC TGTTGCTGCT GCTCATGCAG
TACCTGTGCC GAGAGTACCG CGATGGGAAC CCACGTGTGC GCAGCCTGGT GCAGGACACA
CGCATCCACC TGGTGCCCTC ACTGAACCCT GATGGCTACG AGGTGGCAGC GCAGATGGGC
TCAGAGTTTG GGAACTGGGC GCTGGGACTG TGGACTGAGG AGGGCTTTGA CATCTTTGAA
GATTTCCCGG ATCTCAACTC TGTGCTCTGG GGAGCTGAGG AGAGGAAATG GGTCCCCTAC
CGGGTCCCCA ACAATAACTT GCCCATCCCT GAACGCTACC TTTCGCCAGA TGCCACGGTA
TCCACGGAGG TCCGGGCCAT CATTGCCTGG ATGGAGAAGA ACCCCTTCGT GCTGGGAGCA
AATCTGAACG GCGGCGAGCG GCTAGTATCC TACCCCTACG ATATGGCCCG CACGCCTACC
CAGGAGCAGC TGCTGGCCGC AGCCATGGCA GCAGCCCGGG GGGAGGATGA GGACGAGGTC
TCCGAGGCCC AGGAGACTCC AGACCACGCC ATCTTCCGGT GGCTTGCCAT CTCCTTCGCC
TCCGCACACC TCACCTTGAC CGAGCCCTAC CGCGGAGGCT GCCAAGCCCA GGACTACACC
GGCGGCATGG GCATCGTCAA CGGGGCCAAG TGGAACCCCC GGACCGGGAC TATCAATGAC
TTCAGTTACC TGCATACCAA CTGCCTGGAG CTCTCCTTCT ACCTGGGCTG TGACAAGTTC
CCTCATGAGA GTGAGCTGCC CCGCGAGTGG GAGAACAACA AGGAGGCGCT GCTCACCTTC
ATGGAGCAGG TGCACCGCGG CATTAAGGGG GTGGTGACGG ACGAGCAAGG CATCCCCATT
GCCAACGCCA CCATCTCTGT GAGTGGCATT AATCACGGCG TGAAGACAGC CAGTGGTGGT
GATTACTGGC GAATCTTGAA CCCGGGTGAG TACCGCGTGA CAGCCCACGC GGAGGGCTAC
ACCCCGAGCG CCAAGACCTG CAATGTTGAC TATGACATCG GGGCCACTCA GTGCAACTTC
ATCCTGGCTC GCTCCAACTG GAAGCGCATC CGGGAGATCA TGGCCATGAA CGGGAACCGG
CCTATCCCAC ACATAGACCC ATCGCGCCCT ATGACCCCCC AACAGCGACG CCTGCAGCAG
CGACGCCTAC AACACCGCCT GCGGCTTCGG GCACAGATGC GGCTGCGGCG CCTCAACGCC
ACCACCACCC TAGGCCCCCA CACTGTGCCT CCCACGCTGC CCCCTGCCCC TGCCACCACC
CTGAGCACTA CCATAGAGCC CTGGGGCCTC ATACCGCCAA CCACCGCTGG CTGGGAGGAG
TCGGAGACTG AGACCTACAC AGAGGTGGTG ACAGAGTTTG GGACCGAGGT GGAGCCCGAG
TTTGGGACCA AGGTGGAGCC CGAGTTTGAG ACCCAGTTGG AGCCTGAGTT TGAGACCCAG
CTGGAACCCG AGTTTGAGGA AGAGGAGGAG GAGGAGAAAG AGGAGGAGAT AGCCACTGGC
CAGGCATTCC CCTTCACAAC AGTAGAGACC TACACAGTGA ACTTTGGGGA CTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu56213
Clone ID Related Accession (Same CDS sequence) XM_011515162.1
Accession Version XM_011515162.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3399bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product adipocyte enhancer-binding protein 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGGCGGCCG TGCGCGGGGC GCCCCTGCTC AGCTGCCTCC TGGCGTTGCT GGCCCTGTGC 
CCTGGAGGGC GCCCGCAGAC GGTGCTGACC GACGACGAGA TCGAGGAGTT CCTCGAGGGC
TTCCTGTCAG AGCTAGAACC TGAGCCCCGG GAGGACGACG TGGAGGCCCC GCCGCCTCCC
GAGCCCACCC CGCGGGTCCG AAAAGCCCAG GCGGGGGGCA AGCCAGGGAA GCGGCCAGGG
ACGGCCGCAG AAGTGCCTCC GGAAAAGACC AAAGACAAAG GGAAGAAAGG CAAGAAAGAC
AAAGGCCCCA AGGTGCCCAA GGAGTCCTTG GAGGGGTCCC CCAGGCCGCC CAAGAAGGGG
AAGGAGAAGC CACCCAAGGC CACCAAGAAG CCCAAGGAGA AGCCACCTAA GGCCACCAAG
AAGCCCAAGG AGAAGCCACC CAAGGCCACC AAGAAGCCCA AAGAGAAGCC ACCCAAGGCC
ACCAAGAAGC CCCCGTCAGG GAAGAGGCCC CCCATTCTGG CTCCCTCAGA AACCCTGGAG
TGGCCACTGC CCCCACCCCC CAGCCCTGGC CCCGAGGAGC TACCCCAGGA GGGAGGGGCG
CCCCTCTCAA ATAACTGGCA GAATCCAGGA GAGGAGACCC ATGTGGAGGC ACGGGAGCAC
CAGCCTGAGC CGGAGGAGGA GACCGAGCAA CCCACACTGG ACTACAATGA CCAGATCGAG
AGGGAGGACT ATGAGGACTT TGAGTACATT CGGCGCCAGA AGCAACCCAG GCCACCCCCA
AGCAGAAGGA GGAGGCCCGA GCGGGTCTGG CCAGAGCCCC CTGAGGAGAA GGCCCCGGCC
CCAGCCCCGG AGGAGAGGAT TGAGCCTCCT GTGAAGCCTC TGCTGCCCCC GCTGCCCCCT
GACTATGGTG ATGGTTACGT GATCCCCAAC TACGATGACA AGAAACCCAA AAAGGAGGAC
AGCAGCCCCA AGGAGGAGAC CGACAAGTGG GCAGTGGAGA AGGGCAAGGA CCACAAAGAG
CCCCGAAAGG GCGAGGAGTT GGAGGAGGAG TGGACGCCTA CGGAGAAAGT CAAGTGTCCC
CCCATTGGGA TGGAGTCACA CCGTATTGAG GACAACCAGA TCCGAGCCTC CTCCATGCTG
CGCCACGGCC TGGGGGCACA GCGCGGCCGG CTCAACATGC AGACCGGTGC CACTGAGGAC
GACTACTATG ATGGTGCGTG GTGTGCCGAG GACGATGCCA GGACCCAGTG GATAGAGGTG
GACACCAGGA GGACTACCCG GTTCACAGGC GTCATCACCC AGGGCAGAGA CTCCAGCATC
CATGACGATT TTGTGACCAC CTTCTTCGTG GGCTTCAGCA ATGACAGCCA GACATGGGTG
ATGTACACCA ACGGCTATGA GGAAATGACC TTTCATGGGA ACGTGGACAA GGACACACCC
GTGCTGAGTG AGCTCCCAGA GCCGGTGGTG GCTCGTTTCA TCCGCATCTA CCCACTCACC
TGGAATGGCA GCCTGTGCAT GCGCCTGGAG GTGCTGGGGT GCTCTGTGGC CCCTGTCTAC
AGCTACTACG CACAGAATGA GGTGGTGGCC ACCGATGACC TGGATTTCCG GCACCACAGC
TACAAGGACA TGCGCCAGCT CATGAAGGTG GTGAACGAGG AGTGCCCCAC CATCACCCGC
ACTTACAGCC TGGGCAAGAG CTCACGAGGC CTCAAGATCT ATGCCATGGA GATCTCAGAC
AACCCTGGGG AGCATGAACT GGGGGAGCCC GAGTTCCGCT ACACTGCTGG GATCCATGGC
AACGAGGTGC TGGGCCGAGA GCTGTTGCTG CTGCTCATGC AGTACCTGTG CCGAGAGTAC
CGCGATGGGA ACCCACGTGT GCGCAGCCTG GTGCAGGACA CACGCATCCA CCTGGTGCCC
TCACTGAACC CTGATGGCTA CGAGGTGGCA GCGCAGATGG GCTCAGAGTT TGGGAACTGG
GCGCTGGGAC TGTGGACTGA GGAGGGCTTT GACATCTTTG AAGATTTCCC GGATCTCAAC
TCTGTGCTCT GGGGAGCTGA GGAGAGGAAA TGGGTCCCCT ACCGGGTCCC CAACAATAAC
TTGCCCATCC CTGAACGCTA CCTTTCGCCA GATGCCACGG TATCCACGGA GGTCCGGGCC
ATCATTGCCT GGATGGAGAA GAACCCCTTC GTGCTGGGAG CAAATCTGAA CGGCGGCGAG
CGGCTAGTAT CCTACCCCTA CGATATGGCC CGCACGCCTA CCCAGGAGCA GCTGCTGGCC
GCAGCCATGG CAGCAGCCCG GGGGGAGGAT GAGGACGAGG TCTCCGAGGC CCAGGAGACT
CCAGACCACG CCATCTTCCG GTGGCTTGCC ATCTCCTTCG CCTCCGCACA CCTCACCTTG
ACCGAGCCCT ACCGCGGAGG CTGCCAAGCC CAGGACTACA CCGGCGGCAT GGGCATCGTC
AACGGGGCCA AGTGGAACCC CCGGACCGGG ACTATCAATG ACTTCAGTTA CCTGCATACC
AACTGCCTGG AGCTCTCCTT CTACCTGGGC TGTGACAAGT TCCCTCATGA GAGTGAGCTG
CCCCGCGAGT GGGAGAACAA CAAGGAGGCG CTGCTCACCT TCATGGAGCA GGTGCACCGC
GGCATTAAGG GGGTGGTGAC GGACGAGCAA GGCATCCCCA TTGCCAACGC CACCATCTCT
GTGAGTGGCA TTAATCACGG CGTGAAGACA GCCAGTGGTG GTGATTACTG GCGAATCTTG
AACCCGGGTG AGTACCGCGT GACAGCCCAC GCGGAGGGCT ACACCCCGAG CGCCAAGACC
TGCAATGTTG ACTATGACAT CGGGGCCACT CAGTGCAACT TCATCCTGGC TCGCTCCAAC
TGGAAGCGCA TCCGGGAGAT CATGGCCATG AACGGGAACC GGCCTATCCC ACACATAGAC
CCATCGCGCC CTATGACCCC CCAACAGCGA CGCCTGCAGC AGCGACGCCT ACAACACCGC
CTGCGGCTTC GGGCACAGAT GCGGCTGCGG CGCCTCAACG CCACCACCAC CCTAGGCCCC
CACACTGTGC CTCCCACGCT GCCCCCTGCC CCTGCCACCA CCCTGAGCAC TACCATAGAG
CCCTGGGGCC TCATACCGCC AACCACCGCT GGCTGGGAGG AGTCGGAGAC TGAGACCTAC
ACAGAGGTGG TGACAGAGTT TGGGACCGAG GTGGAGCCCG AGTTTGGGAC CAAGGTGGAG
CCCGAGTTTG AGACCCAGTT GGAGCCTGAG TTTGAGACCC AGCTGGAACC CGAGTTTGAG
GAAGAGGAGG AGGAGGAGAA AGAGGAGGAG ATAGCCACTG GCCAGGCATT CCCCTTCACA
ACAGTAGAGA CCTACACAGT GAACTTTGGG GACTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011513464.1
CDS347..3745
Misc Feature(1)1418..1888
Misc Feature(2)1424..1885
Misc Feature(3)order(1568..1570,1652..1654,1673..1675)
Misc Feature(4)1946..2977
Misc Feature(5)order(2141..2143,2150..2152,2336..2338,2363..2368,2555..2560,2576..2578,2588..2590,2810..2812,2822..2824,2828..2830,2888..2890)
Misc Feature(6)order(2141..2143,2150..2152,2555..2557)
Misc Feature(7)2987..3214
Translation

Target ORF information:

RefSeq Version XM_011515162.1
Organism Homo sapiens(Human)
Definition Homo sapiens AE binding protein 1 (AEBP1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011515162.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGGCGGCCG TGCGCGGGGC GCCCCTGCTC AGCTGCCTCC TGGCGTTGCT GGCCCTGTGC 
CCTGGAGGGC GCCCGCAGAC GGTGCTGACC GACGACGAGA TCGAGGAGTT CCTCGAGGGC
TTCCTGTCAG AGCTAGAACC TGAGCCCCGG GAGGACGACG TGGAGGCCCC GCCGCCTCCC
GAGCCCACCC CGCGGGTCCG AAAAGCCCAG GCGGGGGGCA AGCCAGGGAA GCGGCCAGGG
ACGGCCGCAG AAGTGCCTCC GGAAAAGACC AAAGACAAAG GGAAGAAAGG CAAGAAAGAC
AAAGGCCCCA AGGTGCCCAA GGAGTCCTTG GAGGGGTCCC CCAGGCCGCC CAAGAAGGGG
AAGGAGAAGC CACCCAAGGC CACCAAGAAG CCCAAGGAGA AGCCACCTAA GGCCACCAAG
AAGCCCAAGG AGAAGCCACC CAAGGCCACC AAGAAGCCCA AAGAGAAGCC ACCCAAGGCC
ACCAAGAAGC CCCCGTCAGG GAAGAGGCCC CCCATTCTGG CTCCCTCAGA AACCCTGGAG
TGGCCACTGC CCCCACCCCC CAGCCCTGGC CCCGAGGAGC TACCCCAGGA GGGAGGGGCG
CCCCTCTCAA ATAACTGGCA GAATCCAGGA GAGGAGACCC ATGTGGAGGC ACGGGAGCAC
CAGCCTGAGC CGGAGGAGGA GACCGAGCAA CCCACACTGG ACTACAATGA CCAGATCGAG
AGGGAGGACT ATGAGGACTT TGAGTACATT CGGCGCCAGA AGCAACCCAG GCCACCCCCA
AGCAGAAGGA GGAGGCCCGA GCGGGTCTGG CCAGAGCCCC CTGAGGAGAA GGCCCCGGCC
CCAGCCCCGG AGGAGAGGAT TGAGCCTCCT GTGAAGCCTC TGCTGCCCCC GCTGCCCCCT
GACTATGGTG ATGGTTACGT GATCCCCAAC TACGATGACA AGAAACCCAA AAAGGAGGAC
AGCAGCCCCA AGGAGGAGAC CGACAAGTGG GCAGTGGAGA AGGGCAAGGA CCACAAAGAG
CCCCGAAAGG GCGAGGAGTT GGAGGAGGAG TGGACGCCTA CGGAGAAAGT CAAGTGTCCC
CCCATTGGGA TGGAGTCACA CCGTATTGAG GACAACCAGA TCCGAGCCTC CTCCATGCTG
CGCCACGGCC TGGGGGCACA GCGCGGCCGG CTCAACATGC AGACCGGTGC CACTGAGGAC
GACTACTATG ATGGTGCGTG GTGTGCCGAG GACGATGCCA GGACCCAGTG GATAGAGGTG
GACACCAGGA GGACTACCCG GTTCACAGGC GTCATCACCC AGGGCAGAGA CTCCAGCATC
CATGACGATT TTGTGACCAC CTTCTTCGTG GGCTTCAGCA ATGACAGCCA GACATGGGTG
ATGTACACCA ACGGCTATGA GGAAATGACC TTTCATGGGA ACGTGGACAA GGACACACCC
GTGCTGAGTG AGCTCCCAGA GCCGGTGGTG GCTCGTTTCA TCCGCATCTA CCCACTCACC
TGGAATGGCA GCCTGTGCAT GCGCCTGGAG GTGCTGGGGT GCTCTGTGGC CCCTGTCTAC
AGCTACTACG CACAGAATGA GGTGGTGGCC ACCGATGACC TGGATTTCCG GCACCACAGC
TACAAGGACA TGCGCCAGCT CATGAAGGTG GTGAACGAGG AGTGCCCCAC CATCACCCGC
ACTTACAGCC TGGGCAAGAG CTCACGAGGC CTCAAGATCT ATGCCATGGA GATCTCAGAC
AACCCTGGGG AGCATGAACT GGGGGAGCCC GAGTTCCGCT ACACTGCTGG GATCCATGGC
AACGAGGTGC TGGGCCGAGA GCTGTTGCTG CTGCTCATGC AGTACCTGTG CCGAGAGTAC
CGCGATGGGA ACCCACGTGT GCGCAGCCTG GTGCAGGACA CACGCATCCA CCTGGTGCCC
TCACTGAACC CTGATGGCTA CGAGGTGGCA GCGCAGATGG GCTCAGAGTT TGGGAACTGG
GCGCTGGGAC TGTGGACTGA GGAGGGCTTT GACATCTTTG AAGATTTCCC GGATCTCAAC
TCTGTGCTCT GGGGAGCTGA GGAGAGGAAA TGGGTCCCCT ACCGGGTCCC CAACAATAAC
TTGCCCATCC CTGAACGCTA CCTTTCGCCA GATGCCACGG TATCCACGGA GGTCCGGGCC
ATCATTGCCT GGATGGAGAA GAACCCCTTC GTGCTGGGAG CAAATCTGAA CGGCGGCGAG
CGGCTAGTAT CCTACCCCTA CGATATGGCC CGCACGCCTA CCCAGGAGCA GCTGCTGGCC
GCAGCCATGG CAGCAGCCCG GGGGGAGGAT GAGGACGAGG TCTCCGAGGC CCAGGAGACT
CCAGACCACG CCATCTTCCG GTGGCTTGCC ATCTCCTTCG CCTCCGCACA CCTCACCTTG
ACCGAGCCCT ACCGCGGAGG CTGCCAAGCC CAGGACTACA CCGGCGGCAT GGGCATCGTC
AACGGGGCCA AGTGGAACCC CCGGACCGGG ACTATCAATG ACTTCAGTTA CCTGCATACC
AACTGCCTGG AGCTCTCCTT CTACCTGGGC TGTGACAAGT TCCCTCATGA GAGTGAGCTG
CCCCGCGAGT GGGAGAACAA CAAGGAGGCG CTGCTCACCT TCATGGAGCA GGTGCACCGC
GGCATTAAGG GGGTGGTGAC GGACGAGCAA GGCATCCCCA TTGCCAACGC CACCATCTCT
GTGAGTGGCA TTAATCACGG CGTGAAGACA GCCAGTGGTG GTGATTACTG GCGAATCTTG
AACCCGGGTG AGTACCGCGT GACAGCCCAC GCGGAGGGCT ACACCCCGAG CGCCAAGACC
TGCAATGTTG ACTATGACAT CGGGGCCACT CAGTGCAACT TCATCCTGGC TCGCTCCAAC
TGGAAGCGCA TCCGGGAGAT CATGGCCATG AACGGGAACC GGCCTATCCC ACACATAGAC
CCATCGCGCC CTATGACCCC CCAACAGCGA CGCCTGCAGC AGCGACGCCT ACAACACCGC
CTGCGGCTTC GGGCACAGAT GCGGCTGCGG CGCCTCAACG CCACCACCAC CCTAGGCCCC
CACACTGTGC CTCCCACGCT GCCCCCTGCC CCTGCCACCA CCCTGAGCAC TACCATAGAG
CCCTGGGGCC TCATACCGCC AACCACCGCT GGCTGGGAGG AGTCGGAGAC TGAGACCTAC
ACAGAGGTGG TGACAGAGTT TGGGACCGAG GTGGAGCCCG AGTTTGGGAC CAAGGTGGAG
CCCGAGTTTG AGACCCAGTT GGAGCCTGAG TTTGAGACCC AGCTGGAACC CGAGTTTGAG
GAAGAGGAGG AGGAGGAGAA AGAGGAGGAG ATAGCCACTG GCCAGGCATT CCCCTTCACA
ACAGTAGAGA CCTACACAGT GAACTTTGGG GACTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Aortic carboxypeptidase-like protein (ACLP) enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways.
The Journal of biological chemistry289(5)2526-36(2014 Jan)
Tumelty KE,Smith BD,Nugent MA,Layne MD


book

Berberine-induced inhibition of adipocyte enhancer-binding protein 1 attenuates oxidized low-density lipoprotein accumulation and foam cell formation in phorbol 12-myristate 13-acetate-induced macrophages.
European journal of pharmacology690(1-3)164-9(2012 Sep)
Huang Z,Dong F,Li S,Chu M,Zhou H,Lu Z,Huang W


book

AEBP1 gene variants in infants with gastroschisis.
Birth defects research. Part A, Clinical and molecular teratology94(9)738-42(2012 Sep)
Feldkamp ML,Bowles NE,Botto LD


book

Identification of genomic targets of transcription factor AEBP1 and its role in survival of glioma cells.
Molecular cancer research : MCR10(8)1039-51(2012 Aug)
Ladha J,Sinha S,Bhat V,Donakonda S,Rao SM


book

Proteomics characterization of extracellular space components in the human aorta.
Molecular & cellular proteomics : MCP9(9)2048-62(2010 Sep)
Didangelos A,Yin X,Mandal K,Baumert M,Jahangiri M,Mayr M


 
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