Gene Symbol | BPIFB3 |
Entrez Gene ID | 359710 |
Full Name | BPI fold containing family B member 3 |
Synonyms | C20orf185,LPLUNC3,RYA3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » BPIFB3 cDNA ORF clone
gRNAs
Gene Symbol | BPIFB3 |
Entrez Gene ID | 359710 |
Full Name | BPI fold containing family B member 3 |
Synonyms | C20orf185,LPLUNC3,RYA3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_182658.2 | NP_872599.1 | BPI fold-containing family B member 3 precursor |
NM_001376932.1 | NP_001363861.1 | BPI fold-containing family B member 3 precursor |
NM_182658.3 | NP_872599.1 | BPI fold-containing family B member 3 precursor |
Homo sapiens (human) | BPIFB3 | NP_872599.1 |
Mus musculus (house mouse) | Bpifb3 | NP_919338.2 |
Bos taurus (cattle) | BPIFB3 | NP_001231194.1 |
Rattus norvegicus (Norway rat) | Bpifb3 | NP_001102678.1 |
Gallus gallus (chicken) | BPIL3 | XP_004947239.1 |
Pan troglodytes (chimpanzee) | BPIFB3 | XP_001154813.1 |
BPIFB3 | XP_002798215.1 | |
Canis lupus familiaris (dog) | BPIFB3 | XP_542959.4 |
BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery.
Delorme-Axford E, Morosky S, Bomberger J, Stolz DB, Jackson WT, Coyne CB
mBio5(6)e02147(2014 Dec)
Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.
Bingle CD, Seal RL, Craven CJ
Biochemical Society transactions39(4)977-83(2011 Aug)
Phylogenetic and evolutionary analysis of the PLUNC gene family.
Bingle CD, LeClair EE, Havard S, Bingle L, Gillingham P, Craven CJ
Protein science : a publication of the Protein Society13(2)422-30(2004 Feb)
Expansion of the BPI family by duplication on human chromosome 20: characterization of the RY gene cluster in 20q11.21 encoding olfactory transporters/antimicrobial-like peptides.
Andrault JB, Gaillard I, Giorgi D, Rouquier S
Genomics82(2)172-84(2003 Aug)
PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx.
Bingle CD, Craven CJ
Human molecular genetics11(8)937-43(2002 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Overexpression of BPIFB3 inhibits coxsackievirus B replication, dramatically alters the morphology of LC3B-positive vesicles, and suppresses autophagy in response to rapamycin.
Title: BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery.
Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.
The following BPIFB3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BPIFB3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu79579 | |
Clone ID Related Accession (Same CDS sequence) | NM_182658.2 , NM_001376932.1 , NM_182658.3 | |
Accession Version | NM_182658.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-07 | |
Organism | Homo sapiens(human) | |
Product | BPI fold-containing family B member 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC113398.1 and AF549189.1. On Jan 7, 2015 this sequence version replaced NM_182658.1. ##Evidence-Data-START## Transcript exon combination :: BC113398.1, AF549189.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968832, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## |
1 | ATGCAGCCAG TCATGCTGGC CCTGTGGTCC CTGCTTCTGC TCTGGGGCCT GGCGACTCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_872599.1 |
CDS | 94..1524 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCAGCCAG TCATGCTGGC CCTGTGGTCC CTGCTTCTGC TCTGGGGCCT GGCGACTCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu79579 | |
Clone ID Related Accession (Same CDS sequence) | NM_182658.2 , NM_001376932.1 , NM_182658.3 | |
Accession Version | NM_001376932.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-04 | |
Organism | Homo sapiens(human) | |
Product | BPI fold-containing family B member 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL121756.14. ##Evidence-Data-START## CDS exon combination :: AF549189.1 [ECO:0000331] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## |
1 | ATGCAGCCAG TCATGCTGGC CCTGTGGTCC CTGCTTCTGC TCTGGGGCCT GGCGACTCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001363861.1 |
CDS | 66..1496 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCAGCCAG TCATGCTGGC CCTGTGGTCC CTGCTTCTGC TCTGGGGCCT GGCGACTCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu79579 | |
Clone ID Related Accession (Same CDS sequence) | NM_182658.2 , NM_001376932.1 , NM_182658.3 | |
Accession Version | NM_182658.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-04 | |
Organism | Homo sapiens(human) | |
Product | BPI fold-containing family B member 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL121756.14. On Dec 2, 2019 this sequence version replaced NM_182658.2. ##Evidence-Data-START## Transcript exon combination :: BC113398.1, AF549189.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGCAGCCAG TCATGCTGGC CCTGTGGTCC CTGCTTCTGC TCTGGGGCCT GGCGACTCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_872599.1 |
CDS | 94..1524 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCAGCCAG TCATGCTGGC CCTGTGGTCC CTGCTTCTGC TCTGGGGCCT GGCGACTCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery. |
Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. |
Phylogenetic and evolutionary analysis of the PLUNC gene family. |
Expansion of the BPI family by duplication on human chromosome 20: characterization of the RY gene cluster in 20q11.21 encoding olfactory transporters/antimicrobial-like peptides. |
PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx. |